P M Flynn

Summary

Affiliation: St. Jude Children's Research Hospital
Country: USA

Publications

  1. ncbi request reprint Catheter design influences recurrence of catheter-related bloodstream infection in children with cancer
    Patricia M Flynn
    Department of Infectious Diseases, St Jude Children s Research Hospital, 332 N Lauderdale St, Memphis, TN 38105, USA
    J Clin Oncol 21:3520-5. 2003
  2. ncbi request reprint Virologic and immunologic outcomes after 24 weeks in HIV type 1-infected adolescents receiving highly active antiretroviral therapy
    Patricia M Flynn
    Department of Infectious Diseases, St Jude Children s Research Hospital, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    J Infect Dis 190:271-9. 2004
  3. pmc Pharmacokinetics and safety of single-dose tenofovir disoproxil fumarate and emtricitabine in HIV-1-infected pregnant women and their infants
    Patricia M Flynn
    St Jude Children s Research Hospital, Memphis, Tennessee 138105 2794, USA
    Antimicrob Agents Chemother 55:5914-22. 2011
  4. ncbi request reprint Long-term observation of adolescents initiating HAART therapy: three-year follow-up
    Patricia M Flynn
    Department of Infectious Diseases, St Jude Children s Research Hospital, University of Tennessee Health Science Center, Memphis, Tennessee 38105, USA
    AIDS Res Hum Retroviruses 23:1208-14. 2007
  5. pmc Intracellular pharmacokinetics of once versus twice daily zidovudine and lamivudine in adolescents
    Patricia M Flynn
    Department of Infectious Diseases, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Antimicrob Agents Chemother 51:3516-22. 2007
  6. pmc Hepatitis B vaccination in HIV-infected youth: a randomized trial of three regimens
    Patricia M Flynn
    Department of Infectious Diseases, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Acquir Immune Defic Syndr 56:325-32. 2011
  7. ncbi request reprint Aspergillosis in children with cancer: A 34-year experience
    S Abbasi
    Department of Infectious Diseases, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Clin Infect Dis 29:1210-9. 1999
  8. ncbi request reprint Systemic pharmacokinetics and cellular pharmacology of zidovudine in human immunodeficiency virus type 1-infected women and newborn infants
    J H Rodman
    Pharmaceutical Sciences, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Infect Dis 180:1844-50. 1999
  9. ncbi request reprint MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs
    J D Schuetz
    Department of Pharmaceutical Sciences, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Nat Med 5:1048-51. 1999
  10. ncbi request reprint Candidal meningitis in children with cancer
    J A McCullers
    Departments of Infectious Diseases and Virology and Molecular Biology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Clin Infect Dis 31:451-7. 2000

Research Grants

  1. St. Jude-Memphis Adolescent Trials Unit
    Patricia Flynn; Fiscal Year: 2007
  2. St. Jude/Memphis IMPAACT Clinical Trials Unit
    Patricia Flynn; Fiscal Year: 2007
  3. PEDIATRIC AIDS CLINICAL TRIALS GROUP
    Patricia Flynn; Fiscal Year: 2006

Detail Information

Publications48

  1. ncbi request reprint Catheter design influences recurrence of catheter-related bloodstream infection in children with cancer
    Patricia M Flynn
    Department of Infectious Diseases, St Jude Children s Research Hospital, 332 N Lauderdale St, Memphis, TN 38105, USA
    J Clin Oncol 21:3520-5. 2003
    ....
  2. ncbi request reprint Virologic and immunologic outcomes after 24 weeks in HIV type 1-infected adolescents receiving highly active antiretroviral therapy
    Patricia M Flynn
    Department of Infectious Diseases, St Jude Children s Research Hospital, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    J Infect Dis 190:271-9. 2004
    ..Adolescents represent the fastest growing demographic group of new human immunodeficiency virus (HIV) infections in the United States. At present, there is little information available about their response to therapy...
  3. pmc Pharmacokinetics and safety of single-dose tenofovir disoproxil fumarate and emtricitabine in HIV-1-infected pregnant women and their infants
    Patricia M Flynn
    St Jude Children s Research Hospital, Memphis, Tennessee 138105 2794, USA
    Antimicrob Agents Chemother 55:5914-22. 2011
    ..Rapidly decreasing TFV levels in infants suggest that multiple or higher doses of TDF will be necessary to maintain concentrations that are effective for viral suppression...
  4. ncbi request reprint Long-term observation of adolescents initiating HAART therapy: three-year follow-up
    Patricia M Flynn
    Department of Infectious Diseases, St Jude Children s Research Hospital, University of Tennessee Health Science Center, Memphis, Tennessee 38105, USA
    AIDS Res Hum Retroviruses 23:1208-14. 2007
    ..Interventions, especially those focused on adherence, are necessary to improve HAART outcomes in adolescents...
  5. pmc Intracellular pharmacokinetics of once versus twice daily zidovudine and lamivudine in adolescents
    Patricia M Flynn
    Department of Infectious Diseases, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Antimicrob Agents Chemother 51:3516-22. 2007
    ..056). Although findings were similar between the BID and QD groups, the lower concentrations of ZDV and the number of patients below the level of detection after 24 h suggests that ZDV should continue to be administered BID...
  6. pmc Hepatitis B vaccination in HIV-infected youth: a randomized trial of three regimens
    Patricia M Flynn
    Department of Infectious Diseases, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    J Acquir Immune Defic Syndr 56:325-32. 2011
    ..HIV-infected youth are at risk of hepatitis B infection and should be vaccinated. Previous reports suggest reduced response to standard hepatitis B vaccine regimens...
  7. ncbi request reprint Aspergillosis in children with cancer: A 34-year experience
    S Abbasi
    Department of Infectious Diseases, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Clin Infect Dis 29:1210-9. 1999
    ..0014). Aspergillosis continues to be associated with poor outcome. Development of improved medical and adjuvant therapies, including surgery, is warranted...
  8. ncbi request reprint Systemic pharmacokinetics and cellular pharmacology of zidovudine in human immunodeficiency virus type 1-infected women and newborn infants
    J H Rodman
    Pharmaceutical Sciences, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Infect Dis 180:1844-50. 1999
    ..Studies of simpler oral regimens of zidovudine can now be evaluated regarding the ability to achieve these pharmacologic end points associated with highly effective parenteral therapy...
  9. ncbi request reprint MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs
    J D Schuetz
    Department of Pharmaceutical Sciences, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Nat Med 5:1048-51. 1999
    ..MRP4 is the first transporter, to our knowledge, directly linked to the efflux of nucleoside monophosphate analogs from mammalian cells...
  10. ncbi request reprint Candidal meningitis in children with cancer
    J A McCullers
    Departments of Infectious Diseases and Virology and Molecular Biology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Clin Infect Dis 31:451-7. 2000
    ..The cases were invariably fatal, supporting aggressive treatment of candidal meningitis in immunocompromised patients and further study of the prevention, diagnosis, and management of C. tropicalis meningitis...
  11. ncbi request reprint Oral cefixime is similar to continued intravenous antibiotics in the empirical treatment of febrile neutropenic children with cancer
    J L Shenep
    Department of Infectious Diseases, St Jude Children s Research Hospital, University of Tennessee Health Sciences Center, Memphis, TN 38105, USA
    Clin Infect Dis 32:36-43. 2001
    ..0). Results support the safety of oral cefixime therapy for low-risk febrile neutropenic children, a therapeutic approach that would facilitate earlier outpatient management and decrease the costs of treatment...
  12. pmc Development of a directly observed therapy adherence intervention for adolescents with human immunodeficiency virus-1: application of focus group methodology to inform design, feasibility, and acceptability
    Patricia A Garvie
    Division of Behavioral Medicine, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    J Adolesc Health 44:124-32. 2009
    ..To obtain input from adolescents with human immunodeficiency virus-1 (HIV-1) infection to inform the design of a community-based modified directly observed therapy (MDOT) antiretroviral adherence intervention...
  13. pmc Etiology and clinical course of febrile neutropenia in children with cancer
    Hana Hakim
    Departments of Infectious Diseases, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Pediatr Hematol Oncol 31:623-9. 2009
    ..The etiology, clinical course, and outcome of fever and neutropenia (FN) in children with cancer using the current FN guidelines and diagnostic resources in the United States have not been well described...
  14. pmc Panton-Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus infections in children with cancer
    Ashok Srinivasan
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatr Blood Cancer 53:1216-20. 2009
    ..However, the epidemiology of PVL-positive MRSA infections has not been described in children or adults with cancer...
  15. doi request reprint Implementation of and barriers to routine HIV screening for adolescents
    Timothy D Minniear
    Department of Infectious Diseases, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Pediatrics 124:1076-84. 2009
    ..We developed and implemented a process for routine HIV screening, and we report screening practices and acceptance among adolescents at a large, urban, pediatric emergency department (ED)...
  16. doi request reprint Staphylococcus aureus bacteremia in pediatric patients with cancer
    Ashok Srinivasan
    Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Pediatr Infect Dis J 29:172-4. 2010
    ..Thirty-eight (73%) of the bacteremic episodes were catheter-related. Methicillin resistance was associated with increased catheter removal (P = 0.003), but no increase in complications or adverse outcomes was seen...
  17. doi request reprint Risk prediction in pediatric cancer patients with fever and neutropenia
    Hana Hakim
    Department of Infectious Diseases, Mail Stop 600, St Jude Children s Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105 3678, USA
    Pediatr Infect Dis J 29:53-9. 2010
    ..To identify predictors for 2 risk measures-"proven invasive bacterial infection or culture-negative sepsis (IBD)" and "clinical complications (CC)"-in pediatric cancer patients with fever and neutropenia (FN)...
  18. pmc Short communication: methicillin-resistant Staphylococcus aureus infections in children and young adults infected with HIV
    Ashok Srinivasan
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    AIDS Res Hum Retroviruses 25:1219-24. 2009
    ..PVL-positive MRSA infections were associated with more SSTI ( p=0.043) but not with increased morbidity or a higher risk of complications compared to PVL-negative MRSA infections in children and young adults with HIV...
  19. pmc Recipients of vaccine against the 1976 "swine flu" have enhanced neutralization responses to the 2009 novel H1N1 influenza virus
    Jonathan A McCullers
    Department of Infectious Diseases, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Clin Infect Dis 50:1487-92. 2010
    ..Receipt of a vaccine to a related virus significantly enhanced the neutralization capacity of these responses, suggesting homologous vaccination against the 2009 pandemic H1N1 influenza virus would have a similar effect...
  20. doi request reprint Efficacy and safety of cefepime in pediatric patients: a systematic review and meta-analysis
    Elisabeth E Adderson
    Department of Infectious Diseases, St Jude Children s Research Hospital, Department of Pediatrics, The University of Tennessee Health Sciences Center, Memphis TN 38105, USA
    J Pediatr 157:490-5, 495.e1. 2010
    ..We systematically reviewed clinical trials on the safety and efficacy of cefepime in pediatric patients in view of recent reports, which suggested that cefepime is associated with increased 30-day all-cause mortality rates...
  21. pmc Directly observed therapy (DOT) for nonadherent HIV-infected youth: lessons learned, challenges ahead
    Aditya H Gaur
    Department of Infectious Diseases, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    AIDS Res Hum Retroviruses 26:947-53. 2010
    ..Depressed youth appear to be one subgroup that would benefit from this intervention. Study findings should help inform the design of larger community-based DOT intervention studies in youth...
  22. ncbi request reprint Prophylaxis of Pneumocystis carinii pneumonia with atovaquone in children with leukemia
    Renee M Madden
    Division of Bone Marrow Transplantation, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Cancer 109:1654-8. 2007
    ..Therefore, a retrospective analysis was conducted to determine the incidence of PCP in pediatric patients who received prophylactic atovaquone during treatment for acute leukemia...
  23. ncbi request reprint In situ diagnosis of central venous catheter-related bloodstream infection without peripheral blood culture
    Jeremy A Franklin
    Department of Infectious Diseases, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    Pediatr Infect Dis J 23:614-8. 2004
    ..Comparative quantitative culture of blood obtained via the CVC and a peripheral vein (PV) is a well-accepted method of diagnosing CRBI; however, an alternative definition for use when a PV culture is not available is desirable...
  24. ncbi request reprint Optimum management of pediatric patients with fever and neutropenia
    Aditya H Gaur
    Department of Infectious Diseases, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Indian J Pediatr 71:825-35. 2004
    ..Selection of empiric antibiotics based on ongoing monitoring of antimicrobial susceptibility patterns is emphasized...
  25. ncbi request reprint Newer treatments for fungal infections
    Katherine M Knapp
    Department of Infectious Diseases, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Support Oncol 3:290-8. 2005
    ..The authors describe each of these new compounds and discuss how they fit into the overall management of fungal infections in patients with cancer...
  26. ncbi request reprint Retrospective study of the safety of caspofungin in immunocompromised pediatric patients
    Jeremy A Franklin
    Department of Infectious Diseases, St Jude Children s Research Hospital, 332 N Lauderdale Street, Memphis, TN 381205, USA
    Pediatr Infect Dis J 22:747-9. 2003
  27. ncbi request reprint Diagnosis of catheter-related bloodstream infections among pediatric oncology patients lacking a peripheral culture, using differential time to detection
    Aditya H Gaur
    Department of Infectious Diseases, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Pediatr Infect Dis J 24:445-9. 2005
    ..Both the pain and inconvenience of PV cultures are undesirable...
  28. ncbi request reprint Optimizing blood culture practices in pediatric immunocompromised patients: evaluation of media types and blood culture volume
    Aditya H Gaur
    Department of Infectious Diseases, St Jude Children s Research Hospital, University of Tennessee Health Science Center, 332 N Lauderdale Street, Memphis, TN 38105 2794, USA
    Pediatr Infect Dis J 22:545-52. 2003
    ..The optimal use of blood cultures to determine the etiology of febrile episodes in neutropenic children has not been well-defined...
  29. ncbi request reprint Manifestations of fungal cellulitis of the orbit in children with neutropenia and fever
    Melanie L McCarty
    Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Ophthal Plast Reconstr Surg 20:217-23. 2004
    ..To delineate clinical manifestations of fungal orbital cellulitis in immunocompromized patients...
  30. ncbi request reprint The effect of atovaquone on etoposide pharmacokinetics in children with acute lymphoblastic leukemia
    M E van de Poll
    Department of Pharmaceutical Sciences, St Jude Children's Research Hospital, Memphis, TN 38105, USA
    Cancer Chemother Pharmacol 47:467-72. 2001
    ....
  31. ncbi request reprint Bacillus cereus bacteremia and meningitis in immunocompromised children
    A H Gaur
    Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105, USA
    Clin Infect Dis 32:1456-62. 2001
    ..cereus toxins...
  32. ncbi request reprint Difference in time to detection: a simple method to differentiate catheter-related from non-catheter-related bloodstream infection in immunocompromised pediatric patients
    Aditya H Gaur
    Department of Infectious Diseases, St Jude Children s Research Hospital, University of Tennessee Health Science Center, Memphis, TN 38105 2794, USA
    Clin Infect Dis 37:469-75. 2003
    ....
  33. ncbi request reprint Psychosocial profile of HIV-infected adolescents in a Southern US urban cohort
    H Kadivar
    University of Tennessee Health Science Center, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    AIDS Care 18:544-9. 2006
    ..HIV-infected youth are best served in a comprehensive care environment with immediate access to medical care, social work, and psychology/psychiatry services...
  34. ncbi request reprint Accuracy of percutaneous lung biopsy for invasive pulmonary aspergillosis
    F A Hoffer
    Department of Diagnostic Imaging, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Pediatr Radiol 31:144-52. 2001
    ..Invasive pulmonary aspergillosis is fulminant and often fatal in immunosuppressed patients. Percutaneous biopsy may select patients who could benefit from surgical resection...
  35. ncbi request reprint Efavirenz liquid formulation in human immunodeficiency virus-infected children
    Stuart E Starr
    Division of Infectious and Immunologic Diseases, Abramson Research Center, The Children s Hospital of Philadelphia, PA 19104, USA
    Pediatr Infect Dis J 21:659-63. 2002
    ....
  36. pmc Pharmacokinetics and safety of single oral doses of emtricitabine in human immunodeficiency virus-infected children
    Laurene H Wang
    Triangle Pharmaceuticals, Inc, Gilead Sciences, Inc, Durham, North Carolina 27707, USA
    Antimicrob Agents Chemother 48:183-91. 2004
    ..e., median of approximately 10 h. micro g/ml). This pediatric FTC dose is being evaluated in long-term phase II therapeutic trials in HIV-infected children...
  37. ncbi request reprint Relationship of plasma HIV-1 RNA dynamics to baseline factors and virological responses to highly active antiretroviral therapy in adolescents (aged 12-22 years) infected through high-risk behavior
    Hulin Wu
    Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY 14642, USA
    J Infect Dis 189:593-601. 2004
    ....
  38. ncbi request reprint Immunologic function and virologic suppression among children with perinatally acquired HIV Infection on highly active antiretroviral therapy
    Richard M Rutstein
    Division of General Pediatrics, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Med Care 43:III15-22. 2005
    ..Limited data are available on the level of virologic suppression and immune function of pediatric patients followed in clinical settings in the HAART era...
  39. ncbi request reprint Hospital and outpatient health services utilization among HIV-infected children in care 2000-2001
    Richard M Rutstein
    Division of General Pediatrics, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    Med Care 43:III31-9. 2005
    ..The aging of the pediatric HIV cohort and advances in antiretroviral therapy for children may have resulted in recent changes in patterns of healthcare utilization...
  40. ncbi request reprint Immune reconstitution and predictors of virologic failure in adolescents infected through risk behaviors and initiating HAART: week 60 results from the PACTG 381 cohort
    Bret J Rudy
    Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    AIDS Res Hum Retroviruses 22:213-21. 2006
    ..Several T cell markers were predictive of subsequent virologic failure in subjects achieving short-term success. Further study is warranted to determine whether these predictors provide any benefit to clinical management...
  41. pmc Efficacy, safety and tolerability of tipranavir coadministered with ritonavir in HIV-1-infected children and adolescents
    Juan C Salazar
    Connecticut Children s Medical Center, University of Connecticut School of Medicine, Hartford, Connecticut 06106, USA
    AIDS 22:1789-98. 2008
    ..To evaluate the efficacy, safety and tolerability of ritonavir-boosted tipranavir (TPV/r) in HIV-1-infected pediatric patients...
  42. pmc Model for intracellular Lamivudine metabolism in peripheral blood mononuclear cells ex vivo and in human immunodeficiency virus type 1-infected adolescents
    Zexun Zhou
    Department of Biomedical Engineering, University of Southern California, Los Angeles, CA 90089, USA
    Antimicrob Agents Chemother 50:2686-94. 2006
    ....
  43. ncbi request reprint Ritonavir-based highly active antiretroviral therapy in human immunodeficiency virus type 1-infected infants younger than 24 months of age
    Ellen Gould Chadwick
    Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Pediatr Infect Dis J 24:793-800. 2005
    ..Few data are available regarding clinical outcomes or dosing requirements for the protease inhibitor ritonavir in human immunodeficiency virus (HIV)-infected children younger than under 24 months of age...
  44. pmc Pharmacokinetics of antiretroviral regimens containing tenofovir disoproxil fumarate and atazanavir-ritonavir in adolescents and young adults with human immunodeficiency virus infection
    Jennifer J Kiser
    University of Colorado at Denver and Health Sciences Center, Denver, CO, USA
    Antimicrob Agents Chemother 52:631-7. 2008
    ..Additional studies of the exposure-response relationships of this regimen in children, adolescents, and adults would advance our knowledge of its pharmacodynamic properties...
  45. pmc Analyses of HIV-1 drug-resistance profiles among infected adolescents experiencing delayed antiretroviral treatment switch after initial nonsuppressive highly active antiretroviral therapy
    Allison Agwu
    Department of Pediatrics, Division of Infectious Diseases, Johns Hopkins Medical Institution, Baltimore, Maryland, USA
    AIDS Patient Care STDS 22:545-52. 2008
    ..This finding may have implications for initial treatment regimens and transmission risk in HIV-infected youth, a group with rising infection rates...
  46. ncbi request reprint Micafungin (FK463), alone or in combination with other systemic antifungal agents, for the treatment of acute invasive aspergillosis
    David W Denning
    Education and Research Centre, Wythenshawe Hospital and University of Manchester, Academic Department of Medicine and Surgery, Southmoor Road, Manchester M23 9LT, UK
    J Infect 53:337-49. 2006
    ..This study evaluated the safety and efficacy of micafungin in patients with proven or probable invasive aspergillosis (IA)...
  47. pmc Pharmacokinetics, safety, and tolerability of caspofungin in children and adolescents
    Thomas J Walsh
    Immunocompromised Host Section, Pediatric Oncology Branch, National Cancer Institute, Bldg 10 CRC, Room 1W 5750, 10 Center Drive, Bethesda, Maryland 20892, USA
    Antimicrob Agents Chemother 49:4536-45. 2005
    ..These results demonstrate that caspofungin at 1 mg/kg/day in pediatric patients is suboptimal. Caspofungin administration at 50 mg/m2/day provides a comparable exposure to that of adult patients treated with 50 mg/day...
  48. ncbi request reprint Recruitment and retention of adolescent participants in HIV research: findings from the REACH (Reaching for Excellence in Adolescent Care and Health) Project
    Paulette D Stanford
    University of Medicine and Dentistry of New Jersey, Newark, New Jersey 07103 2714, USA stanfopd umdnj edu
    J Adolesc Health 32:192-203. 2003
    ..To evaluate the importance of 13 items in the recruitment and retention of HIV-positive and HIV-negative adolescent participants in a longitudinal study (REACH study)...

Research Grants5

  1. St. Jude-Memphis Adolescent Trials Unit
    Patricia Flynn; Fiscal Year: 2007
    ..An ATU in Memphis would offer the combined advantages of an established, productive clinical research center with the proximity of a large at-risk population to maximize realization of the research efforts in the adolescent population. ..
  2. St. Jude/Memphis IMPAACT Clinical Trials Unit
    Patricia Flynn; Fiscal Year: 2007
    ..administrative component: ..
  3. PEDIATRIC AIDS CLINICAL TRIALS GROUP
    Patricia Flynn; Fiscal Year: 2006
    ..abstract_text> ..