- Chemotherapeutic agents circumvent emergence of dasatinib-resistant BCR-ABL kinase mutations in a precise mouse model of Philadelphia chromosome-positive acute lymphoblastic leukemiaNidal Boulos
Department of Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
Blood 117:3585-95. 2011....
- Whole-body physiologically based pharmacokinetic model for nutlin-3a in mice after intravenous and oral administrationFan Zhang
Department of Pharmaceutical Sciences, Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
Drug Metab Dispos 39:15-21. 2011..The final model was used to perform simulations of unbound tissue concentrations to determine which dosing regimens are appropriate for preclinical models of several pediatric malignancies...