Christina N Lessov-Schlaggar

Summary

Affiliation: SRI International
Country: USA

Publications

  1. ncbi Longitudinal genetic analysis of executive function in elderly men
    Christina N Lessov-Schlaggar
    Center for Health Sciences, SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025, USA
    Neurobiol Aging 28:1759-68. 2007
  2. ncbi Heritability of cigarette smoking and alcohol use in Chinese male twins: the Qingdao twin registry
    Christina N Lessov-Schlaggar
    SRI International, Center for Health Sciences, Menlo Park, CA, USA
    Int J Epidemiol 35:1278-85. 2006
  3. pmc Genetics of nicotine dependence and pharmacotherapy
    Christina N Lessov-Schlaggar
    Center for Health Sciences, SRI International, Menlo Park, CA 94025, USA
    Biochem Pharmacol 75:178-95. 2008
  4. ncbi Support for previously identified alcoholism susceptibility Loci in a cohort selected for smoking behavior
    Kirk C Wilhelmsen
    Department of Neurology, Gallo Institute, Center for Health Sciences, SRI International, Menlo Park, California, USA
    Alcohol Clin Exp Res 29:2108-15. 2005
  5. ncbi Genetic and environmental sources of variation in heart rate response to infused nicotine in twins
    Gary E Swan
    Center for Health Sciences, SRI International, Menlo Park, CA 94025, USA
    Cancer Epidemiol Biomarkers Prev 16:1057-64. 2007
  6. pmc Longitudinal genetic analysis of brain volumes in normal elderly male twins
    Christina N Lessov-Schlaggar
    Center for Health Sciences, SRI International, Menlo Park, CA, USA
    Neurobiol Aging 33:636-44. 2012
  7. pmc Validity of recall of tobacco use in two prospective cohorts
    Janet Brigham
    Center for Health Sciences, SRI International, Menlo Park, California 94025, USA
    Am J Epidemiol 172:828-35. 2010
  8. pmc Genetic and environmental influences on the ratio of 3'hydroxycotinine to cotinine in plasma and urine
    Gary E Swan
    Center for Health Sciences, SRI International, Menlo Park, CA 94025, USA
    Pharmacogenet Genomics 19:388-98. 2009
  9. doi Reliability of adult retrospective recall of lifetime tobacco use
    Janet Brigham
    SRI International, Menlo Park, CA 94043, USA
    Nicotine Tob Res 10:287-99. 2008
  10. doi The Twin Research Registry at SRI International
    Ruth E Krasnow
    Center for Health Sciences, SRI International, Menlo Park, CA, USA
    Twin Res Hum Genet 16:463-70. 2013

Detail Information

Publications24

  1. ncbi Longitudinal genetic analysis of executive function in elderly men
    Christina N Lessov-Schlaggar
    Center for Health Sciences, SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025, USA
    Neurobiol Aging 28:1759-68. 2007
    ..These results suggest that common genetic factors underlie longitudinal EF task performance. Genetic influences on EF decline, however, appear to be evident at longer time intervals between assessments...
  2. ncbi Heritability of cigarette smoking and alcohol use in Chinese male twins: the Qingdao twin registry
    Christina N Lessov-Schlaggar
    SRI International, Center for Health Sciences, Menlo Park, CA, USA
    Int J Epidemiol 35:1278-85. 2006
    ..In 2000, the Chinese National Twin Registry was established to provide a genetically informative resource for investigation of health behaviour including tobacco and alcohol use...
  3. pmc Genetics of nicotine dependence and pharmacotherapy
    Christina N Lessov-Schlaggar
    Center for Health Sciences, SRI International, Menlo Park, CA 94025, USA
    Biochem Pharmacol 75:178-95. 2008
    ....
  4. ncbi Support for previously identified alcoholism susceptibility Loci in a cohort selected for smoking behavior
    Kirk C Wilhelmsen
    Department of Neurology, Gallo Institute, Center for Health Sciences, SRI International, Menlo Park, California, USA
    Alcohol Clin Exp Res 29:2108-15. 2005
    ..In this paper we use, for the first time, linkage analysis to search for alcoholism-related phenotypes in a family sample selected for smoking behavior...
  5. ncbi Genetic and environmental sources of variation in heart rate response to infused nicotine in twins
    Gary E Swan
    Center for Health Sciences, SRI International, Menlo Park, CA 94025, USA
    Cancer Epidemiol Biomarkers Prev 16:1057-64. 2007
    ..The contribution from genetic sources to heart rate response characteristics should be investigated further as a potential endophenotype for use in genetic studies of nicotine dependence...
  6. pmc Longitudinal genetic analysis of brain volumes in normal elderly male twins
    Christina N Lessov-Schlaggar
    Center for Health Sciences, SRI International, Menlo Park, CA, USA
    Neurobiol Aging 33:636-44. 2012
    ..The results of this study are discussed in the context of the small sample size and associated limitations of statistical power...
  7. pmc Validity of recall of tobacco use in two prospective cohorts
    Janet Brigham
    Center for Health Sciences, SRI International, Menlo Park, California 94025, USA
    Am J Epidemiol 172:828-35. 2010
    ..These findings support the utility of collecting recalled self-report information for reconstructing salient lifetime health behaviors and underscore the need for careful interpretation...
  8. pmc Genetic and environmental influences on the ratio of 3'hydroxycotinine to cotinine in plasma and urine
    Gary E Swan
    Center for Health Sciences, SRI International, Menlo Park, CA 94025, USA
    Pharmacogenet Genomics 19:388-98. 2009
    ..This analysis sought to conduct a combined genetic epidemiologic and pharmacogenetic investigation of the 3HC/COT ratio in plasma and urine...
  9. doi Reliability of adult retrospective recall of lifetime tobacco use
    Janet Brigham
    SRI International, Menlo Park, CA 94043, USA
    Nicotine Tob Res 10:287-99. 2008
    ..Few differences in the reliability of recall were apparent between sexes and between age groups. These results indicate that recall of important tobacco use information can form a reliable basis for research...
  10. doi The Twin Research Registry at SRI International
    Ruth E Krasnow
    Center for Health Sciences, SRI International, Menlo Park, CA, USA
    Twin Res Hum Genet 16:463-70. 2013
    ..Twins in the TRR have participated in studies of complex, clinically relevant phenotypes that would not be feasible to measure in larger samples...
  11. pmc Association of tobacco dependence and quit attempt duration with Rasch-modeled withdrawal sensitivity using retrospective measures
    Harold S Javitz
    Center for Health Sciences, SRI International, Menlo Park, CA 94025, USA
    Addiction 104:1027-35. 2009
    ..To examine whether Rasch modeling would yield a unidimensional withdrawal sensitivity measure correlating with factors associated with successful smoking cessation...
  12. pmc Genome-wide linkage of cotinine pharmacokinetics suggests candidate regions on chromosomes 9 and 11
    Yungang He
    Center for Health Sciences, SRI International, Menlo Park, California 94025, USA
    Am J Med Genet B Neuropsychiatr Genet 150:554-9. 2009
    ..96 (P = 0.0013) and 1.94 (P = 0.0014). The confidence level of the linkage between the three genome regions and cotinine pharmacokinetics is statistically significant with a genome-wide empirical probability of P = 0.029...
  13. ncbi Tobacco addiction and pharmacogenetics of nicotine metabolism
    Gary E Swan
    Center for Health Sciences, SRI International, Menlo Park, California 94025, USA
    J Neurogenet 23:262-71. 2009
    ....
  14. ncbi Apolipoprotein E epsilon4 and change in cognitive functioning in community-dwelling older adults
    Gary E Swan
    Center for Health Sciences, SRI International, Menlo Park, California 94025, USA
    J Geriatr Psychiatry Neurol 18:196-201. 2005
    ..A significant gender x APOE epsilon4 interaction was seen for change in performance on short delay cued recall. These results suggest that APOE epsilon4 is associated with cognitive decline differently in older adult men and women...
  15. pmc Dopamine genes and nicotine dependence in treatment-seeking and community smokers
    Andrew W Bergen
    Center for Health Sciences, SRI International, Menlo Park, CA 94025, USA
    Neuropsychopharmacology 34:2252-64. 2009
    ..A community cohort of N=175 multiplex ever-smoking pedigrees (N=423 ever smokers) provided nominal evidence for association with the FTND at these top ranked SNPs, uncorrected for multiple comparisons...
  16. ncbi The effects of tobacco smoke and nicotine on cognition and the brain
    Gary E Swan
    Center for Health Sciences, SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025, USA
    Neuropsychol Rev 17:259-73. 2007
    ....
  17. pmc Test-retest reliability of web-based retrospective self-report of tobacco exposure and risk
    Janet Brigham
    Center for Health Sciences, SRI International, Menlo Park, CA, USA
    J Med Internet Res 11:e35. 2009
    ..Establishing the reliability of retrospective measures is a necessary step in determining the utility of that methodology and in studying behaviors in the context of risk and protective factors...
  18. doi Nature versus nurture in gout: a twin study
    Eswar Krishnan
    Division of Immunology and Rheumatology, Stanford University School of Medicine, Palo Alto, CA, USA
    Am J Med 125:499-504. 2012
    ..Some rare forms of gout have a known genetic basis, but the relative importance of genetic factors on the risk for the lifetime prevalence of gout is not clear...
  19. pmc A genome-wide screen for nicotine dependence susceptibility loci
    Gary E Swan
    Center for Health Sciences, SRI International, Menlo Park, California, USA
    Am J Med Genet B Neuropsychiatr Genet 141:354-60. 2006
    ..Several of the corresponding support intervals were near putative loci reported previously (on chromosomes 6, 7, and 8) while others appear to be novel (on chromosomes 5, 16, and 19)...
  20. ncbi Female sex and oral contraceptive use accelerate nicotine metabolism
    Neal L Benowitz
    Division of Clinical Pharmacology and Experimental Therapeutics, Medical Service, San Francisco General Hospital Medical Center, University of California, San Francisco, San Francisco 94143 1220, USA
    Clin Pharmacol Ther 79:480-8. 2006
    ..This study tested the hypothesis that women metabolize nicotine more rapidly than men and that, among women, oral contraceptive users metabolize nicotine more rapidly than nonusers of oral contraceptives...
  21. doi Gamma-aminobutyric acid receptor genes and nicotine dependence: evidence for association from a case-control study
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Addiction 103:1027-38. 2008
    ....
  22. ncbi Gender differences in determinants of smoking initiation and persistence in California twins
    Ann S Hamilton
    Department of Preventive Medicine, University of Southern California, Los Angeles, USA
    Cancer Epidemiol Biomarkers Prev 15:1189-97. 2006
    ..To determine the effects of genetic versus environmental influences on smoking initiation (SI) and smoking persistence (SP)...
  23. doi Adolescent smoking trajectories and nicotine dependence
    Christina N Lessov-Schlaggar
    Washington University, St Louis, MO 63110, USA
    Nicotine Tob Res 10:341-51. 2008
    ....
  24. ncbi CYP2A6 genotype and the metabolism and disposition kinetics of nicotine
    Neal L Benowitz
    Division of Clinical Pharmacology and Experimental Therapeutics, Medical Service, San Francisco General Hospital Medical Center, and Department of Medicine, University of California, San Francisco, San Francisco 94143 1220, USA
    Clin Pharmacol Ther 80:457-67. 2006
    ..Our objective was to determine the relationship between variant CYP2A6 genotypes and the disposition and metabolism of nicotine administered intravenously...