James N Mubiru

Summary

Affiliation: Southwest Foundation for Biomedical Research
Country: USA

Publications

  1. ncbi request reprint A preliminary study of the baboon prostate pathophysiology
    James N Mubiru
    Southwest National Primate Research Center, Southwest Foundation for Biomedical Research, San Antonio, Texas 78227 5301, USA
    Prostate 67:1421-31. 2007
  2. pmc Nonhuman primates as models for studies of prostate specific antigen and prostatic diseases
    James N Mubiru
    Southwest National Primate Research Center, Southwest Foundation for Biomedical Research, San Antonio, Texas 78245 0549, USA
    Prostate 68:1546-54. 2008
  3. pmc Serum prostate specific antigen changes in cynomolgus monkeys (Macaca fascicularis) on a high sugar high fat diet
    James N Mubiru
    Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX 78245 0549, USA
    Prostate 72:469-75. 2012
  4. ncbi request reprint A variant of the alpha-methyl-acyl-CoA racemase gene created by a deletion in exon 5 and its expression in prostate cancer
    James N Mubiru
    Department of Pathology, The University of Texas Health Science Center, San Antonio, 78229, USA
    Prostate 65:117-23. 2005
  5. pmc Correlation between presence of Trypanosoma cruzi DNA in heart tissue of baboons and cynomolgus monkeys, and lymphocytic myocarditis
    James N Mubiru
    Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, Texas Department of Biology, St Mary s University, San Antonio, Texas
    Am J Trop Med Hyg 90:627-33. 2014
  6. pmc Analysis of prostate-specific antigen transcripts in chimpanzees, cynomolgus monkeys, baboons, and African green monkeys
    James N Mubiru
    Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, Texas, United States of America
    PLoS ONE 9:e94522. 2014
  7. pmc Androgen receptor CAG repeat polymorphism in males of six non-human primate species
    James N Mubiru
    Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA
    J Med Primatol 41:67-70. 2012
  8. ncbi request reprint Alternative spliced variants of the alpha-methylacyl-CoA racemase gene and their expression in prostate cancer
    James N Mubiru
    Department of Pathology, Mail Code 7750, University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    Gene 327:89-98. 2004
  9. pmc A preliminary report on the feeding of cynomolgus monkeys (Macaca fascicularis) with a high-sugar high-fat diet for 33 weeks
    James N Mubiru
    Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA
    J Med Primatol 40:335-41. 2011
  10. pmc Polymerase chain reaction detection of Trypanosoma cruzi in Macaca fascicularis using archived tissues
    Jeff T Williams
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas 78245 0549, USA
    Am J Trop Med Hyg 81:228-34. 2009

Detail Information

Publications10

  1. ncbi request reprint A preliminary study of the baboon prostate pathophysiology
    James N Mubiru
    Southwest National Primate Research Center, Southwest Foundation for Biomedical Research, San Antonio, Texas 78227 5301, USA
    Prostate 67:1421-31. 2007
    ..At present there are no suitable animal models for these diseases. This study explores the potential use of the baboon as a model for prostatic diseases...
  2. pmc Nonhuman primates as models for studies of prostate specific antigen and prostatic diseases
    James N Mubiru
    Southwest National Primate Research Center, Southwest Foundation for Biomedical Research, San Antonio, Texas 78245 0549, USA
    Prostate 68:1546-54. 2008
    ..However, PSA has clinical limitations as a screen for prostatic diseases due to its low sensitivity and specificity. There is a strong need to better understand the biology of PSA and factors affecting its serum levels...
  3. pmc Serum prostate specific antigen changes in cynomolgus monkeys (Macaca fascicularis) on a high sugar high fat diet
    James N Mubiru
    Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX 78245 0549, USA
    Prostate 72:469-75. 2012
    ..An inverse relationship between serum prostate specific antigen (PSA) levels and body mass index (BMI) has been reported in men but not in any animal model...
  4. ncbi request reprint A variant of the alpha-methyl-acyl-CoA racemase gene created by a deletion in exon 5 and its expression in prostate cancer
    James N Mubiru
    Department of Pathology, The University of Texas Health Science Center, San Antonio, 78229, USA
    Prostate 65:117-23. 2005
    ..Alternatively spliced variants of AMACR have recently been reported, however, their role in prostate cancer pathogenesis is unclear...
  5. pmc Correlation between presence of Trypanosoma cruzi DNA in heart tissue of baboons and cynomolgus monkeys, and lymphocytic myocarditis
    James N Mubiru
    Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, Texas Department of Biology, St Mary s University, San Antonio, Texas
    Am J Trop Med Hyg 90:627-33. 2014
    ..A positive correlation between PCR positivity and lymphocytic myocarditis in both baboons and cynomolgus monkeys is shown. We also show epicarditis as a common finding in animals infected with T. cruzi...
  6. pmc Analysis of prostate-specific antigen transcripts in chimpanzees, cynomolgus monkeys, baboons, and African green monkeys
    James N Mubiru
    Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, Texas, United States of America
    PLoS ONE 9:e94522. 2014
    ..A codon-based analysis (dN/dS) of the PSA gene identified potential adaptive evolution at five residue sites (Arg45, Lys70, Gln144, Pro189, and Thr203). ..
  7. pmc Androgen receptor CAG repeat polymorphism in males of six non-human primate species
    James N Mubiru
    Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA
    J Med Primatol 41:67-70. 2012
    ..Androgen receptor [CAG](n) microsatellite has been linked to human diseases...
  8. ncbi request reprint Alternative spliced variants of the alpha-methylacyl-CoA racemase gene and their expression in prostate cancer
    James N Mubiru
    Department of Pathology, Mail Code 7750, University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    Gene 327:89-98. 2004
    ..These observations have implications for the cellular localization and function of these AMACR variants...
  9. pmc A preliminary report on the feeding of cynomolgus monkeys (Macaca fascicularis) with a high-sugar high-fat diet for 33 weeks
    James N Mubiru
    Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA
    J Med Primatol 40:335-41. 2011
    ..The metabolic syndrome is common in populations exposed to a typical Western diet. There is a lack of an animal model that mimics this condition...
  10. pmc Polymerase chain reaction detection of Trypanosoma cruzi in Macaca fascicularis using archived tissues
    Jeff T Williams
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas 78245 0549, USA
    Am J Trop Med Hyg 81:228-34. 2009
    ..Successful use of DNA from formalin-fixed, paraffin-embedded blocks is important because most pathology laboratories routinely archive wax blocks. This archived resource can be used for further studies on the prevalence of this disease...