Paul Durham

Summary

Affiliation: Southwest Minnesota State University
Country: USA

Publications

  1. ncbi request reprint CGRP receptor antagonists: a new choice for acute treatment of migraine?
    Paul L Durham
    Southwest Missouri State University, Department of Biology, 225 Temple Hall, Springfield, MO 65804, USA
    Curr Opin Investig Drugs 5:731-5. 2004
  2. ncbi request reprint New insights into the molecular actions of serotonergic antimigraine drugs
    Paul L Durham
    Department of Biology, 225 Temple Hall, Southwest Missouri State University, Springfield, MO 65804, USA
    Pharmacol Ther 94:77-92. 2002
  3. ncbi request reprint Stimulation of the calcitonin gene-related peptide enhancer by mitogen-activated protein kinases and repression by an antimigraine drug in trigeminal ganglia neurons
    Paul L Durham
    Department of Physiology and Biophysics, University of Iowa, Iowa City, Iowa 52242, USA
    J Neurosci 23:807-15. 2003
  4. pmc Effect of carbon dioxide on calcitonin gene-related peptide secretion from trigeminal neurons
    Carrie Vause
    Missouri State University Biology, Department of Biology, Springfield, MO 65897, USA
    Headache 47:1385-97. 2007
  5. pmc Neuron-glia signaling in trigeminal ganglion: implications for migraine pathology
    Srikanth Thalakoti
    Department of Biology, Missouri State University, Springfield, MO 65897, USA
    Headache 47:1008-23; discussion 24-5. 2007
  6. ncbi request reprint Repression of stimulated calcitonin gene-related peptide secretion by topiramate
    Paul L Durham
    Department of Biology, Missouri State University, Springfield, MO, USA
    Headache 46:1291-5. 2006
  7. pmc Calcitonin gene-related peptide (CGRP) and migraine
    Paul L Durham
    Department of Biology, Missouri State University, 231 Temple Hall, Springfield, MO 65897, USA
    Headache 46:S3-8. 2006
  8. pmc Nitric oxide regulation of calcitonin gene-related peptide gene expression in rat trigeminal ganglia neurons
    Jamie Bellamy
    Department of Biology, 225 Temple Hall, Missouri State University, Springfield, MO 65897, USA
    Eur J Neurosci 23:2057-66. 2006
  9. ncbi request reprint Salivary levels of CGRP and VIP in rhinosinusitis and migraine patients
    Jaime L Bellamy
    Department of Biology, Missouri State University, MO 65804, USA
    Headache 46:24-33. 2006
  10. ncbi request reprint CGRP-receptor antagonists--a fresh approach to migraine therapy?
    Paul L Durham
    Department of Biology, Southwest Missouri State University, Springfield, USA
    N Engl J Med 350:1073-5. 2004

Collaborators

  • Elisabeth Nilsson
  • Carrie V Vause
  • Jing Li
  • Marcie J Abbey
  • Vinit V Patil
  • Carrie Vause
  • Srikanth Thalakoti
  • Jaime L Bellamy
  • Jamie Bellamy
  • Andrew F Russo
  • Silvia Mora
  • Srikanth Damodaram
  • Elizabeth Bowen
  • Lauren E Langford
  • Stacy E Freeman
  • Egilius Spierings
  • Elizabeth J Bowen
  • Roger K Cady
  • Jeffrey E Pessin
  • Andreas Jeromin
  • Jeffery R Smith

Detail Information

Publications15

  1. ncbi request reprint CGRP receptor antagonists: a new choice for acute treatment of migraine?
    Paul L Durham
    Southwest Missouri State University, Department of Biology, 225 Temple Hall, Springfield, MO 65804, USA
    Curr Opin Investig Drugs 5:731-5. 2004
    ..This review will discuss the therapeutic potential of olcegepant, the first non-peptide CGRP receptor antagonist available for human studies, within the context of current neurovascular theories on migraine pathology...
  2. ncbi request reprint New insights into the molecular actions of serotonergic antimigraine drugs
    Paul L Durham
    Department of Biology, 225 Temple Hall, Southwest Missouri State University, Springfield, MO 65804, USA
    Pharmacol Ther 94:77-92. 2002
    ....
  3. ncbi request reprint Stimulation of the calcitonin gene-related peptide enhancer by mitogen-activated protein kinases and repression by an antimigraine drug in trigeminal ganglia neurons
    Paul L Durham
    Department of Physiology and Biophysics, University of Iowa, Iowa City, Iowa 52242, USA
    J Neurosci 23:807-15. 2003
    ..We propose that activation of MAPK pathways may increase CGRP gene expression during migraine, and that sumatriptan can diametrically oppose that activation via a prolonged elevation of intracellular calcium...
  4. pmc Effect of carbon dioxide on calcitonin gene-related peptide secretion from trigeminal neurons
    Carrie Vause
    Missouri State University Biology, Department of Biology, Springfield, MO 65897, USA
    Headache 47:1385-97. 2007
    ..The goal of this study was to determine whether the physiological effects of carbon dioxide (CO(2)) involve regulation of CGRP secretion from trigeminal sensory neurons...
  5. pmc Neuron-glia signaling in trigeminal ganglion: implications for migraine pathology
    Srikanth Thalakoti
    Department of Biology, Missouri State University, Springfield, MO 65897, USA
    Headache 47:1008-23; discussion 24-5. 2007
    ..The goal of this study was to investigate neuronal-glial cell signaling in trigeminal ganglia under basal and inflammatory conditions using an in vivo model of trigeminal nerve activation...
  6. ncbi request reprint Repression of stimulated calcitonin gene-related peptide secretion by topiramate
    Paul L Durham
    Department of Biology, Missouri State University, Springfield, MO, USA
    Headache 46:1291-5. 2006
    ..The goal of the proposed research was to determine the effect of topiramate on basal and stimulated release of calcitonin gene-related peptide (CGRP) from trigeminal ganglia neurons...
  7. pmc Calcitonin gene-related peptide (CGRP) and migraine
    Paul L Durham
    Department of Biology, Missouri State University, 231 Temple Hall, Springfield, MO 65897, USA
    Headache 46:S3-8. 2006
    ....
  8. pmc Nitric oxide regulation of calcitonin gene-related peptide gene expression in rat trigeminal ganglia neurons
    Jamie Bellamy
    Department of Biology, 225 Temple Hall, Missouri State University, Springfield, MO 65897, USA
    Eur J Neurosci 23:2057-66. 2006
    ..In summary, our results provide new insight into the cellular mechanisms by which nitric oxide induces CGRP synthesis and secretion from trigeminal neurons...
  9. ncbi request reprint Salivary levels of CGRP and VIP in rhinosinusitis and migraine patients
    Jaime L Bellamy
    Department of Biology, Missouri State University, MO 65804, USA
    Headache 46:24-33. 2006
    ..Analysis of these neuropeptides in human saliva samples can be used as markers of trigeminal and parasympathetic nerve activity in patients between and during attacks as well as in response to specific treatments...
  10. ncbi request reprint CGRP-receptor antagonists--a fresh approach to migraine therapy?
    Paul L Durham
    Department of Biology, Southwest Missouri State University, Springfield, USA
    N Engl J Med 350:1073-5. 2004
  11. ncbi request reprint Regulation of calcitonin gene-related peptide secretion from trigeminal nerve cells by botulinum toxin type A: implications for migraine therapy
    Paul L Durham
    Department of Biology, Southwest Missouri State University, MO, USA
    Headache 44:35-42; discussion 42-3. 2004
    ..To determine the effect of botulinum toxin type A on calcitonin gene-related peptide secretion from cultured trigeminal ganglia neurons...
  12. ncbi request reprint Neuronal expression and regulation of CGRP promoter activity following viral gene transfer into cultured trigeminal ganglia neurons
    Paul L Durham
    Department of Biology, Southwest Missouri State University, Springfield, MO 65804, USA
    Brain Res 997:103-10. 2004
    ..Thus, adenoviral gene transfer can be used in trigeminal ganglia neurons for studying the mechanisms of triptan drug action on CGRP synthesis...
  13. pmc Repression of calcitonin gene-related peptide expression in trigeminal neurons by a Theobroma cacao extract
    Marcie J Abbey
    Department of Biology, Missouri State University, 901 S National Avenue, Springfield, MO 65897, USA
    J Ethnopharmacol 115:238-48. 2008
    ..Release of calcitonin gene-related peptide (CGRP) from trigeminal nerves promotes inflammation in peripheral tissues and nociception...
  14. ncbi request reprint NCS-1 inhibits insulin-stimulated GLUT4 translocation in 3T3L1 adipocytes through a phosphatidylinositol 4-kinase-dependent pathway
    Silvia Mora
    Department of Physiology and Biophysics, University of Iowa, 51 Newton Road, Iowa City, IA 52246, USA
    J Biol Chem 277:27494-500. 2002
    ..These data demonstrate that PI 4-kinase functions to negatively regulate GLUT4 translocation through its interaction with NCS-1...
  15. pmc Calcitonin gene-related peptide stimulation of nitric oxide synthesis and release from trigeminal ganglion glial cells
    Jing Li
    Department of Biology, Missouri State University, Springfield, Missouri 65897, USA
    Brain Res 1196:22-32. 2008
    ....