Research Topics
Species | Andrew F ShorrSummaryAffiliation: Southern Iron Disorders Center Country: USA Publications
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Detail Information
Publications
Comparison of platelet transfusion as fresh whole blood versus apheresis platelets for massively transfused combat trauma patients (CME)Jeremy G Perkins
Walter Reed Army Medical Center, Washington, DC 20307, USA
Transfusion 51:242-52. 2011..In massively transfused trauma patients, we compared outcomes of patients receiving FWB to those receiving aPLT...
Application of a population-based severity scoring system to individual patients results in frequent misclassificationFrank V Booth
Eli Lilly and Company, Indianapolis, IN, USA
Crit Care 9:R522-9. 2005..This study reports the AP2 scoring errors of researchers involved in a large sepsis trial and models the consequences of such an error rate for individual severe sepsis patients...
Epidemiology and economic impact of meticillin-resistant Staphylococcus aureus: review and analysis of the literatureAndrew F Shorr
Pulmonary and Critical Care Medicine, Washington Hospital Center, Washington, DC 20010, USA
Pharmacoeconomics 25:751-68. 2007..Current opinion favours rational prescribing to maximise therapeutic benefit and minimise the risk of further antibacterial resistance...- Cost-effectiveness analysis of a silver-coated endotracheal tube to reduce the incidence of ventilator-associated pneumoniaAndrew F Shorr
Washington Hospital Center, DC 20010, USA
Infect Control Hosp Epidemiol 30:759-63. 2009..To conduct a cost-effectiveness analysis of the economic outcomes of ventilator-associated pneumonia (VAP) prevention associated with silver-coated endotracheal tubes versus uncoated endotracheal tubes... - Epidemiology of staphylococcal resistanceAndrew F Shorr
Pulmonary and Critical Care Medicine and Pulmonary Clinic, Washington Hospital Center, Washington, DC 20010, USA
Clin Infect Dis 45:S171-6. 2007..Improvements in the preparation and dissemination of antibiograms, along with adequate public reporting of MRSA trends, are needed to address the challenge of choosing appropriate initial antibiotic treatment for MRSA infections... - Review of studies of the impact on Gram-negative bacterial resistance on outcomes in the intensive care unitAndrew F Shorr
Department of Pulmonary and Critical Care Medicine, Washington Hospital Center, Washington DC, USA
Crit Care Med 37:1463-9. 2009..To review studies addressing mortality, length of stay (LOS), and cost of resistant Gram-negative bacterial infections in the intensive care unit (ICU)... - Ventilator-associated pneumonia: insights from recent clinical trialsAndrew F Shorr
Pulmonary and Critical Care Medicine Service, Department of Medicine, Walter Reed Army Medical Center, Washington, DC, USA
Chest 128:583S-591S. 2005..This review highlights selected areas of new clinical research on VAP treatment and prevention in order to place their significance in context... - Linezolid versus vancomycin for Staphylococcus aureus bacteraemia: pooled analysis of randomized studiesAndrew F Shorr
Pulmonary, Critical Care and Respiratory Services, Washington Hospital Center, 110 Irving Street NW, Room 2A38 D, Washington, DC 20010, USA
J Antimicrob Chemother 56:923-9. 2005..To compare outcomes in patients with Staphylococcus aureus bacteraemia treated with linezolid with those of vancomycin-treated patients... - Bacteremia in Staphylococcus aureus pneumonia: outcomes and epidemiologyMatthew P Schreiber
Pulmonary and Critical Care Medicine, Washington Hospital Center, Washington, DC 20010, USA
J Crit Care 26:395-401. 2011..Although bacteremia may complicate S aureus pneumonia, the epidemiology of and outcomes associated with bacteremia in this syndrome are poorly described... - Severe acute hypertension among inpatients admitted from the emergency departmentAndrew F Shorr
Pulmonary and Critical Care Medicine Service, Washington Hospital Center, Washington, DC 20010, USA
J Hosp Med 7:203-10. 2012..Hospitalists often treat patients with severe acute hypertension (AH) presenting to the hospital. Little is known about the epidemiology of this syndrome... - Linezolid for treatment of ventilator-associated pneumonia: a cost-effective alternative to vancomycinAndrew F Shorr
Pulmonary and Critical Care Medicine Service, Walter Reed Army Medical Center, Washington, DC, USA
Crit Care Med 32:137-43. 2004..CONCLUSIONS: Linezolid is a cost-effective alternative to vancomycin for the treatment of ventilator-associated pneumonia... - Levofloxacin for treatment of ventilator-associated pneumonia: a subgroup analysis from a randomized trialAndrew F Shorr
Pulmonary and Critical Care Medicine Service, Walter Reed Army Medical Center, Washington, DC 20307, USA
Clin Infect Dis 40:S123-9. 2005..imipenem-cilastatin) was not predictive of outcomes, thus suggesting that the treatment regimens were equivalent. Both levofloxacin and imipenem-cilastatin regimens were well tolerated and had similar adverse event profiles... - Economic implications of an evidence-based sepsis protocol: can we improve outcomes and lower costs?Andrew F Shorr
Pulmonary and Critical Care Medicine Section, Washington Hospital Center, USA
Crit Care Med 35:1257-62. 2007..To determine the financial impact of a sepsis protocol designed for use in the emergency department... - Venous thromboembolism in critically ill patients. Observations from a randomized trial in sepsisAndrew F Shorr
Pulmonary and Critical Care Department, Room 2A 38D, Washington Hospital Center, 110 Irving St, NW, Washington, DC 20010, USA
Thromb Haemost 101:139-44. 2009..Despite multiple guidelines, physicians do not uniformly prescribe VTE prophylaxis. Nonetheless, early VTE occurs even in persons given DAA. Most VTE in critically ill patients are clinically silent... - Comparison of cost, effectiveness, and safety of injectable anticoagulants used for thromboprophylaxis after orthopedic surgeryAndrew F Shorr
Pulmonary and Critical Care, Washington Hospital Center, Washington, DC 20010, USA
Am J Health Syst Pharm 64:2349-55. 2007..The cost, effectiveness, and safety of injectable anticoagulants used for thromboprophylaxis after orthopedic surgery were compared... - Healthcare-associated bloodstream infection: A distinct entity? Insights from a large U.S. databaseAndrew F Shorr
Washington Hospital Center, Washington, DC, USA
Crit Care Med 34:2588-95. 2006..To gain a better understanding of the epidemiology, microbiology, and outcomes of early-onset, culture-positive, community-acquired, healthcare-associated, and hospital-acquired bloodstream infections... - Invasive approaches to the diagnosis of ventilator-associated pneumonia: a meta-analysisAndrew F Shorr
Walter Reed Army Medical Center, Washington, DC, USA
Crit Care Med 33:46-53. 2005..Invasive strategies do not alter mortality. Invasive approaches to ventilator-associated pneumonia affect antibiotic use and prescribing... - Inappropriate therapy for methicillin-resistant Staphylococcus aureus: resource utilization and cost implicationsAndrew F Shorr
Pulmonary and Critical Care Medicine Service, Washington Hospital Center and Georgetown University, Washington, DC, USA
Crit Care Med 36:2335-40. 2008..Initially inappropriate antibiotic therapy for methicillin-resistant S. aureus increases the risk for mortality. The impact of initially inappropriate antibiotic therapy on hospital length of stay and costs remains unknown... - Levofloxacin 750-mg for 5 days for the treatment of hospitalized Fine Risk Class III/IV community-acquired pneumonia patientsAndrew F Shorr
Department of Medicine, Pulmonary and Critical Care Medicine, Room 2A 38D, Washington Hospital Center, 110 Irving St NW, Washington, DC 20010, USA
Respir Med 100:2129-36. 2006..This subgroup analysis attempted to compare the safety and efficacy of a short-course levofloxacin regimen with traditional levofloxacin dosing for PSI Class III/IV patients... - The distance-saturation product predicts mortality in idiopathic pulmonary fibrosisChristopher J Lettieri
Pulmonary and Critical Care Medicine, Walter Reed Army Medical Center, 6900 Georgia Ave, NW, Washington, DC 20307, USA
Respir Med 100:1734-41. 2006..We compared the performance of the DSP to the individual 6MWT parameters in predicting mortality... - Resistant pathogens in nonnosocomial pneumonia and respiratory failure: is it time to refine the definition of health-care-associated pneumonia?Matthew P Schreiber
Pulmonary and Critical Care Medicine, Washington Hospital Center, Washington, DC, USA
Chest 137:1283-8. 2010..The concept of health-care-associated pneumonia (HCAP) exists to identify patients infected with highly resistant pathogens. It is unclear how precise this concept is and how well it performs as a screening tool for resistance... - Do clinical features allow for accurate prediction of fungal pathogenesis in bloodstream infections? Potential implications of the increasing prevalence of non-albicans candidemiaAndrew F Shorr
Pulmonary and Critical Care Medicine, Washington Hospital Center, Washington, DC, USA
Crit Care Med 35:1077-83. 2007..To describe the evolving epidemiology of fungal bloodstream infections in critically ill and noncritically ill patients and to identify predictors of infection with non-albicans yeast species... - Transfusion practice and blood stream infections in critically ill patientsAndrew F Shorr
Pulmonary, Critical Care, and Sleep Medicine Service, Department of Surgery, Walter Reed Army Medical Center, Washington, DC 20307, USA
Chest 127:1722-8. 2005..To examine the relationship between packed RBC (pRBC) transfusion and the development of ICU-acquired bloodstream infections (BSIs).. - Prediction of infection due to antibiotic-resistant bacteria by select risk factors for health care-associated pneumoniaAndrew F Shorr
Pulmonary and Critical Care Section, Room 2A 38D, Washington Hospital Center, 110 Irving St NW, Washington, DC 20010, USA
Arch Intern Med 168:2205-10. 2008..The concept of health care-associated pneumonia (HCAP) attempts to capture this, but its predictive value is unclear... - A multicenter, randomized, double-blind, retrospective comparison of 5- and 10-day regimens of levofloxacin in a subgroup of patients aged > or =65 years with community-acquired pneumoniaAndrew F Shorr
Pulmonary, Critical Care, and Sleep Medicine Service, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
Clin Ther 27:1251-9. 2005.... - Morbidity and cost burden of methicillin-resistant Staphylococcus aureus in early onset ventilator-associated pneumoniaAndrew F Shorr
Pulmonary and Critical Care Medicine Service, Washington Hospital Center, Washington, District of Columbia, USA
Crit Care 10:R97. 2006.... - Methicillin-resistant Staphylococcus aureus prolongs intensive care unit stay in ventilator-associated pneumonia, despite initially appropriate antibiotic therapyAndrew F Shorr
Pulmonary and Critical Care Medicine, Washington Hospital Center, Washington, DC, USA
Crit Care Med 34:700-6. 2006..Confronting the adverse impact of MRSA will require efforts that address more than the initial antibiotic prescription... - Burden of sodium abnormalities in patients hospitalized for heart failureAndrew F Shorr
Washington Hospital Center, Washington, DC, USA
Congest Heart Fail 17:1-7. 2011..0001). Sodium abnormalities were common in patients hospitalized for CHF. Adverse outcomes resulted not only from severe hyponatremia, but also from mild hyponatremia and hypernatremia... - Impact of antibiotic guideline compliance on duration of mechanical ventilation in critically ill patients with community-acquired pneumoniaAndrew F Shorr
Pulmonary and Critical Care Section, Department of Medicine, Room 2A 38D, Washington Hospital Center, Washington, DC 20010, USA
Chest 130:93-100. 2006..Our goal was to assess the impact of following these guidelines, such as those from the Infectious Disease Society of America (IDSA), on the duration of mechanical ventilation (MV)... - Inappropriate antibiotic therapy in Gram-negative sepsis increases hospital length of stayAndrew F Shorr
Washington Hospital Center, Washington, DC, USA
Crit Care Med 39:46-51. 2011..To describe the impact of initially inappropriate antibiotic therapy on hospital length of stay in Gram-negative severe sepsis and septic shock... - Low-molecular weight heparin for deep vein thrombosis prophylaxis in hospitalized medical patients: results from a cost-effectiveness analysisAndrew F Shorr
Pulmonary and Critical Care Medicine Service, Washington Hospital Center, 110 Irving Street NW, Washington, DC 20010, USA
Blood Coagul Fibrinolysis 18:309-16. 2007..We conclude that, despite their higher cost, LMWHs for thromboprophylaxis in medical patients result in savings... - Validation of a novel risk score for severity of illness in acute exacerbations of COPDAndrew F Shorr
Pulmonary and Critical Care Medicine, Washington Hospital Center, 110 Irving St, NW, Washington, DC 20010, USA
Chest 140:1177-83. 2011..Clinicians lack a validated tool for risk stratification in acute exacerbations of COPD (AECOPD). We sought to validate the BAP-65 (elevated BUN, altered mental status, pulse > 109 beats/min, age > 65 years) score for this purpose... - Prevention of venous thromboembolism in neurosurgery: a metaanalysisJacob F Collen
Department of Medicine, Walter Reed Army Medical Center, Washington, DC, USA
Chest 134:237-49. 2008..We conducted a systematic review asking, "Among patients undergoing neurosurgical procedures, how safe and effective is the prophylactic use of heparin and mechanical devices?".. - Candidemia on presentation to the hospital: development and validation of a risk scoreAndrew F Shorr
Pulmonary and Critical Care Medicine Service, Washington Hospital Center, Washington, DC 20010, USA
Crit Care 13:R156. 2009..Candidemia results in substantial morbidity and mortality, especially if initial antifungal therapy is delayed or is inappropriate; however, candidemia is difficult to diagnose because of its nonspecific presentation... - Transfusion practice and nosocomial infection: assessing the evidenceAndrew F Shorr
Pulmonary and Critical Care Medicine Section, Washington Hospital Center, Washington, DC 20010, USA
Curr Opin Crit Care 11:468-72. 2005..To evaluate recent literature describing the potential relation between transfusion practice in the intensive care unit and the subsequent risk for nosocomial infection... - Protein C: a potential biomarker in severe sepsis and a possible tool for monitoring treatment with drotrecogin alfa (activated)Andrew F Shorr
Department of Medicine, Section of Pulmonary and Critical Care Medicine, Washington Hospital Center, Irving Street, Washington, District of Columbia 20010, USA
Crit Care 12:R45. 2008..The goal of this study was to identify a dependable, sensitive measure with which to monitor disease progression and response in patients during DrotAA treatment... - Postdischarge oral versus injectable anticoagulation following major orthopedic surgeryAndrew F Shorr
Pulmonary and Critical Care, Washington Hospital Center, Georgetown University, Washington, DC 34685, USA
Ann Pharmacother 42:1222-8. 2008..Multiple clinical studies have shown postdischarge anticoagulation to be beneficial following major orthopedic surgery (MOS); however, outpatient prophylaxis is not widely practiced... - Red blood cell transfusion and ventilator-associated pneumonia: A potential link?Andrew F Shorr
Pulmonary and Critical Care Medicine Service, Walter Reed Army Medical Center, Washington, DC, USA
Crit Care Med 32:666-74. 2004..To determine the relationship between packed red blood cell transfusion practice and the development of ventilator-associated pneumonia (VAP)... - Factors associated with acute lung injury in combat casualties receiving massive blood transfusions: a retrospective analysisChee M Chan
Pulmonary and Critical Care Department, Washington Hospital Center, Georgetown University Medical Center, Washington, DC 20010, USA
J Crit Care 27:419.e7-14. 2012..We sought to determine if use of warm fresh whole blood (WFWB), rather than blood component therapy, alters rates of acute lung injury (ALI) in patients with trauma... - Randomized trial evaluating serial protein C levels in severe sepsis patients treated with variable doses of drotrecogin alfa (activated)Andrew F Shorr
Washington Hospital Center, 110 Irving Street NW, Washington DC 20010, USA
Crit Care 14:R229. 2010..The purpose of this study was to evaluate the dose and duration of drotrecogin alfa (activated) treatment using serial measurements of protein C compared to standard therapy in patients with severe sepsis... - Prevalence and outcomes of pulmonary arterial hypertension in advanced idiopathic pulmonary fibrosisChristopher J Lettieri
Walter Reed Army Medical Center, Department of Pulmonary and Critical Care, 6900 Georgia Avenue NW, Washington, DC 20307, USA
Chest 129:746-52. 2006..We sought to characterize the prevalence of PAH and its impact on survival in patients with advanced IPF... - Sarcoidosis, race, and short-term outcomes following lung transplantationAndrew F Shorr
Pulmonary and Critical Care Medicine Service, Department of Medicine, Walter Reed Army Medical Center, Washington, DC 20307, USA
Chest 125:990-6. 2004..Patients with sarcoidosis, many of whom are African American, may require lung transplantation (LT). Little is known about survival following LT for sarcoidosis... - Cost-minimization analysis of two algorithms for diagnosing acute pulmonary embolismChristopher W Humphreys
Pulmonary and Critical Care Medicine Service, Department of Medicine, Walter Reed Army Medical Center, Washington, DC 20307, USA
Thromb Res 113:275-82. 2004..We hypothesized that an algorithmic approach to diagnosis of pulmonary embolism based upon clinical risk stratification and D-dimer testing would be less costly than a standard approach... - Diagnostics and epidemiology in ventilator-associated pneumoniaAndrew F Shorr
Pulmonary and Critical Care Medicine, Room 2A 68D, Washington Hospital Center, 110 Irving Street NW, Washington, DC 20010, USA
Ther Adv Respir Dis 5:121-30. 2011..Second, select cohorts of patients are at high risk for VAP, and patient case-mix clearly influences the epidemiology of VAP. Third, rates of VAP appear higher outside the US, irrespective of the diagnostic paradigm utilized... - Quality pneumonia care: distinguishing community-acquired from health care-associated pneumoniaAndrew F Shorr
Washington Hospital Center, Washington, DC 20010, USA
Am J Health Syst Pharm 66:S8-14. 2009..Differences in the definition, demographics, risk factors, etiology, and treatment for health care-associated pneumonia (HCAP) versus community-acquired pneumonia (CAP) are discussed... - Fluconazole prophylaxis in critically ill surgical patients: a meta-analysisAndrew F Shorr
Washington Hospital Center, Medstar, Potomac, MD, USA
Crit Care Med 33:1928-35; quiz 1936. 2005..To evaluate the impact of fluconazole prophylaxis on the incidence of fungal infections and on mortality among critically ill surgical patients... - Burden of early-onset candidemia: analysis of culture-positive bloodstream infections from a large U.S. databaseAndrew F Shorr
Pulmonary Critical Care, Washington Hospital Center, Potomac, MD, USA
Crit Care Med 37:2519-26; quiz 2535. 2009..To characterize the epidemiology and burden of early-onset, nonnosocomial candidemia... - Clinical and economic outcomes for patients with health care-associated Staphylococcus aureus pneumoniaAndrew F Shorr
Washington Hospital Center, Washington, DC, USA
J Clin Microbiol 48:3258-62. 2010..aureus HCAP have evidence of MRSA infection. S. aureus HCAP, irrespective of MRSA versus MSSA status, is associated with significant mortality and high health care costs, despite appropriate initial antibiotic therapy... - Differences between low-molecular-weight and unfractionated heparin for venous thromboembolism prevention following ischemic stroke: a metaanalysisAndrew F Shorr
Pulmonary and Critical Care Medicine, Washington Hospital Center, Room 2A 39D, 110 Irving St, NW, Washington, DC 20010, USA
Chest 133:149-55. 2008..Venous thromboembolism (VTE) remains a major cause of morbidity following stroke. The optimal form of pharmacologic prophylaxis following stroke is unknown... - Outcomes with micafungin in patients with candidaemia or invasive candidiasis due to Candida glabrata and Candida kruseiAndrew F Shorr
Pulmonary and Critical Care, Washington Hospital Center, 110 Irving St NW, Washington, DC 20010, USA
J Antimicrob Chemother 66:375-80. 2011..Infection with Candida glabrata and Candida krusei represents a major challenge. We sought to describe outcomes for patients with candidaemia/invasive candidiasis (C/IC) due to these pathogens who were treated with micafungin... - Venous thromboembolism after orthopedic surgery: implications of the choice for prophylaxisAndrew F Shorr
Pulmonary and Critical Care Medicine Section, Washington Hospital Center, Washington, DC 20010, USA
Thromb Res 121:17-24. 2007..We retrospectively analyzed a large hospital discharge database to assess the occurrence of clinically detected VTE as a function of the injectable antithrombotic agent used for VTE prophylaxis in orthopedic surgery... - Practical utility of clinical prediction rules for suspected acute pulmonary embolism in a large academic institutionLisa K Moores
Pulmonary and Critical Care Medicine Service, Walter Reed Army Medical Center, Building 2, WD 77, 6900 Georgia Avenue NW, Washington, DC 20307 5001, USA
Thromb Res 113:1-6. 2004..We sought to determine the utility of these algorithms in patients with suspected PE in a large, tertiary, academic medical center... - Acute kidney injury and cardiovascular outcomes in acute severe hypertensionLynda A Szczech
Department of Medicine, Division of Nephrology, Duke University Medical Center, Box 3646, Durham, NC 27710, USA
Circulation 121:2183-91. 2010.... - Discordance between general and pulmonary pathologists in the diagnosis of interstitial lung diseaseChristopher J Lettieri
Pulmonary and Critical Care Medicine, Department of Medicine, Walter Reed Army Medical Center, 6900 Georgia Ave, NW Washington, DC 20307, USA
Respir Med 99:1425-30. 2005..However, the agreement between general and pulmonary pathologists in histopathologic diagnosis of ILD has not been established... - Outcomes for patients with sarcoidosis awaiting lung transplantationAndrew F Shorr
Pulmonary and Critical Care Medicine Service, Walter Reed Army Medical Center, Washington, DC 20307, USA
Chest 122:233-8. 2002..Nonetheless, patients with sarcoidosis are less likely to undergo OLT. Pulmonary hypertension is a major concern in patients with advanced sarcoidosis awaiting transplantation... - Guidelines and quality for community-acquired pneumonia: measures from the Joint Commission and the Centers for Medicare and Medicaid ServicesAndrew F Shorr
Department of Medicine, Washington Hospital Center, Washington, DC 20010, USA
Am J Health Syst Pharm 66:S2-7. 2009..The rationales for and recent updates on quality measures for the treatment of community-acquired pneumonia (CAP) are reviewed... - Anemia in chronic obstructive pulmonary disease: epidemiology and economic implicationsAndrew F Shorr
Washington Hospital Center, Washington, DC 20010, USA
Curr Med Res Opin 24:1123-30. 2008..Because no data studies have been performed either in a single center or a subpopulation of COPD patients, anemia's influence on the outcomes is not fully understood... - Ventilator-associated pneumonia: the clinical pulmonary infection score as a surrogate for diagnostics and outcomeMarya D Zilberberg
School of Public Health and Health Sciences, University of Massachusetts, Amherst, DC, USA
Clin Infect Dis 51:S131-5. 2010..At present, the CPIS has a limited role both clinically and as a research tool... - Quinolones for treatment of nosocomial pneumonia: a meta-analysisAndrew F Shorr
Pulmonary and Critical Care Medicine Service, Walter Reed Army Medical Center, Washington, DC 20307, USA
Clin Infect Dis 40:S115-22. 2005..12 (95% confidence interval, 0.80-1.55). Neither microbiological eradication rates nor mortality rates varied on the basis of antimicrobial selection... - Twice vs three times daily heparin dosing for thromboembolism prophylaxis in the general medical population: A metaanalysisChristopher S King
Department of Medicine, Walter Reed Army Medical Center, 6900 Georgia Ave NW, Washington, DC 20307, USA
Chest 131:507-16. 2007..While twice-daily (BID) and three-times-daily (TID) dosing regimens have been studied, the two have never been directly compared. We performed a metaanalysis to assess whether TID is superior to BID dosing in the prevention of VTE... - Update in ventilator-associated pneumoniaWilliam L Jackson
Critical Care Medicine Service, Department of Surgery, Walter Reed Army Medical Center, Washington, DC 20010, USA
Curr Opin Anaesthesiol 19:117-21. 2006..Hopefully, additional work will aid in eventual development of effective preventive, diagnostic and therapeutic strategies that can reliably improve patient outcomes... - Minimizing costs for treating deep vein thrombosis: the role for fondaparinuxAndrew F Shorr
Pulmonary and Critical Care Medicine, Washington Hospital Center, 110 Irving St, NW, Washington, DC 20010, USA
J Thromb Thrombolysis 23:229-36. 2007.... - The pharmacoeconomics of deep vein thrombosis treatmentAndrew F Shorr
Pulmonary and Critical Care Medicine Service, Washington Hospital Center, Washington, DC 20010, USA
Am J Med 120:S35-41. 2007..A recent cost-effective analysis demonstrated that fondaparinux use offers an attractive economic alternative to other agents for initial DVT therapy that could yield cost savings without compromising clinical outcomes or patient safety... - Depreotide scanning in sarcoidosis: a pilot studyAndrew F Shorr
Pulmonary and Critical Care Medicine Service, Walter Reed Army Medical Center, 6900 Georgia Avenue NW, Washington, DC 20307, USA
Chest 126:1337-43. 2004..To determine whether sarcoidosis results in uptake on (99m)Tc-labeled depreotide (DP) scintigraphy and to generate preliminary data to guide the development of future trials exploring this imaging modality in sarcoidosis patients... - D-dimer correlates with proinflammatory cytokine levels and outcomes in critically ill patientsAndrew F Shorr
Pulmonary and Critical Care Medicine Service, Walter Reed Army Medical Center, Washington, DC, USA
Chest 121:1262-8. 2002..To determine the relationship between d-dimer (DD) and both proinflammatory and anti-inflammatory cytokine levels, and to confirm the association between DD status and outcomes in critically ill patients... - Preventing pneumonia: the role for pneumococcal and influenza vaccinesAndrew F Shorr
Pulmonary and Critical Care Medicine, Walter Reed Army Medical Center, 6900 Georgia Avenue, NW, Washington, DC 20307, USA
Clin Chest Med 26:123-34. 2005..The pneumococcal and influenza vaccines are considered cost-effective options for pneumonia prevention... - Predicting mortality in patients with sarcoidosis awaiting lung transplantationAndrew F Shorr
Pulmonary and Critical Care Medicine Service, Walter Reed Army Medical Center, 6900 Georgia Avenue NW, Washington, DC 20307, USA
Chest 124:922-8. 2003..To identify factors associated with mortality in patients with sarcoidosis listed for lung transplantation, and to create a model for predicting intermediate-term mortality in these individuals... - An update on cost-effectiveness analysis in critical careAndrew F Shorr
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Walter Reed Army Medical Center, Washington, DC 20307, USA
Curr Opin Crit Care 8:337-43. 2002..With a framework for evaluating these studies, clinicians can better apply their findings to their own institutions... - Protein C concentrations in severe sepsis: an early directional change in plasma levels predicts outcomeAndrew F Shorr
Department of Medicine, Section of Pulmonary and Critical Care Medicine, Washington Hospital Center, Washington, DC, USA
Crit Care 10:R92. 2006..The objective of this study was to determine whether early directional changes in protein C levels correlate with outcome... - Acute eosinophilic pneumonia among US Military personnel deployed in or near IraqAndrew F Shorr
Pulmonary, Critical Care, and Sleep Medicine Service, Walter Reed Army Medical Center, Washington, DC 20307, USA
JAMA 292:2997-3005. 2004..Acute eosinophilic pneumonia (AEP) is a rare disease of unknown etiology characterized by respiratory failure, radiographic infiltrates, and eosinophilic infiltration of the lung... - Correlates of clinical failure in ventilator-associated pneumonia: insights from a large, randomized trialAndrew F Shorr
Pulmonary and Critical Care Medicine, Washington Hospital Center, Washington, DC, USA
J Crit Care 23:64-73. 2008..Our objective was to determine clinical variables measured at baseline and day 3 that may relate to failure of resolution of ventilator-associated pneumonia (VAP)... - Health care-associated candidemia--a distinct entity?Joyti Gulia
Pulmonary and Critical Care Medicine Service, Department of Medicine, Washington Hospital Center, Washington, DC 20010, USA
J Hosp Med 5:298-301. 2010..Although epidemiologic studies document the clear existence of health care-associated pneumonia, little is known about fungal pathogens and their role in HCAIs... - New choices for central venous catheters: potential financial implicationsAndrew F Shorr
Pulmonary and Critical Care Medicine Service, Department of Medicine, Walter Reed Army Medical Center, Washington, DC, USA
Chest 124:275-84. 2003..To determine the cost-effectiveness of the newer antiseptic and antibiotic-impregnated central venous catheters (CVCs) relative to uncoated CVCs and to each other... - Outcomes and safety of surgical lung biopsy for interstitial lung diseaseChristopher J Lettieri
Pulmonary and Critical Care Medicine Service, Walter Reed Army Medical Center, Washington, DC 20307, USA
Chest 127:1600-5. 2005..To determine the safety of surgical lung biopsy (SLB) in patients with interstitial lung disease (ILD), and specifically in those with idiopathic pulmonary fibrosis (IPF)... - Pulmonary infiltrates in the non-HIV-infected immunocompromised patient: etiologies, diagnostic strategies, and outcomesAndrew F Shorr
Pulmonary and Critical Care Medicine Service, Walter Reed Army Medical Center, Washington, DC 20307, USA
Chest 125:260-71. 2004..With the results of invasive testing, these treatments are then narrowed. Frustratingly, outcomes for immunocompromised patients with infiltrates remain poor... - Is the implementation of research findings in the critically ill hampered by the lack of universal definitions of illness?Shannon S Carson
Pulmonary and Critical Care Medicine, University of North Carolina, Chapel Hill, North Carolina 27599 7020, USA
Curr Opin Crit Care 9:308-15. 2003..More specific identifiers of critical illnesses using specific biochemical or genetic markers are being explored. This approach may also be useful for staging disease... - Effect of standardized orders and provider education on head-of-bed positioning in mechanically ventilated patientsDonald L Helman
Pulmonary and Critical Care Medicine Service, Walter Reed Army Medical Center, Washington, DC, USA
Crit Care Med 31:2285-90. 2003..In an era of cost-conscious medicine, interventions that utilize protocols and education programs should be emphasized... - Interferon gamma-1b as therapy for idiopathic pulmonary fibrosis. An intrapatient analysisSteven D Nathan
Inova Transplant Center, Inova Fairfax Hospital, Falls Church, VA 22042, USA
Respiration 71:77-82. 2004..We report our results using this medication in a cohort of patients with a wide range of severity of IPF... - Linezolid does not increase the risk of thrombocytopenia in patients with nosocomial pneumonia: comparative analysis of linezolid and vancomycin useStanley A Nasraway
Division of Surgical Critical Care, Department of Surgery, Tufts New England Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
Clin Infect Dis 37:1609-16. 2003..Clinically significant thrombocytopenia was uncommon in our analysis, and linezolid was not associated with a greater risk of thrombocytopenia in seriously ill patients than was vancomycin... - The protein C pathway: implications for the design of the RESPOND studyBurkhard Vangerow
Eli Lilly Critical Care Europe, Air Center, 1214 Vernier Geneva, Switzerland
Crit Care 11:S4. 2007.... - Dollars and sense in the intensive care unit: the costs of ventilator-associated pneumoniaAndrew F Shorr
Crit Care Med 31:1582-3. 2003 - Not everything that can be counted counts Lee E Morrow
Chest 133:336-7. 2008 - The quick and the dead: the importance of rapid evaluation of infiltrates in the immunocompromised patientAndrew F Shorr
Chest 122:9-12. 2002 - Mortality from time of listing for transplantation as an indicator of candidate outcomesSteven D Nathan
Inova Transplant Center, Inova Fairfax Hospital, Falls Church, VA, USA
Prog Transplant 14:29-32. 2004..It may also help foster the development of an "alternate" list for transplantation and prove useful in helping determine organ prioritization... - There is no "cap" on the importance of community-acquired pneumonia in the ICUAndrew F Shorr
Chest 133:590-2. 2008 - Hyponatremia and hospital outcomes among patients with pneumonia: a retrospective cohort studyMarya D Zilberberg
Evi Med Research Group, LLC, Goshen, Massachusetts, USA
BMC Pulm Med 8:16. 2008..Hyponatremia, occurring in >1/4 of patients with CAP, is associated with greater disease severity and worsened outcomes... - Making the wrong choice: Consequences for patients with infections due to methicillin-resistant Staphylococcus aureusAndrew F Shorr
Crit Care Med 34:2239-41. 2006 - Health care-associated pneumonia: identification and initial management in the EDFredrick M Abrahamian
David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
Am J Emerg Med 26:1-11. 2008..The aim of this article is to create awareness of the entity known as HCAP and to provide knowledge of its identification and initial management in the emergency department... - Anemia, transfusions and hospital outcomes among critically ill patients on prolonged acute mechanical ventilation: a retrospective cohort studyMarya D Zilberberg
School of Public Health and Health Sciences, University of Massachusetts, North Pleasant Street, Amherst, Massachusetts 01003, USA
Crit Care 12:R60. 2008..We hypothesized that transfusions among patients receiving PAMV are common and associated with worsened clinical and economic outcomes... - Red blood cell transfusions and the risk of acute respiratory distress syndrome among the critically ill: a cohort studyMarya D Zilberberg
School of Public Health and Health Sciences, University of Massachusetts, Amherst, P, O, Box 303, Goshen, MA 01032, USA
Crit Care 11:R63. 2007..Uncertainty remains regarding the strength of this relationship... - Transfusion practice in the ICU: when will we apply the evidence?Andrew F Shorr
Chest 127:702-5. 2005 - Dynamic evolution of coagulopathy in the first day of severe sepsis: relationship with mortality and organ failureJean Francois Dhainaut
Department of Intensive Care, Cochin Hospital, AP HP, Cochin Institute, Cochin Port Royal Medical School, Paris V University, Paris, France
Crit Care Med 33:341-8. 2005..To determine whether changes in coagulation biomarkers during the first day of severe sepsis correlate with progression from single to multiple organ failure and subsequent death... - The value of pretest probability and modified clinical pulmonary infection score to diagnose ventilator-associated pneumoniaFrancois Lauzier
Department of Medicine, McMaster University, Hamilton, Ontario, Canada
J Crit Care 23:50-7. 2008..The aim of the study was to assess the utility of pretest probability and modified clinical pulmonary infection score CPIS in the diagnosis of late-onset ventilator-associated pneumonia (VAP)... - Resistance in the intensive care unit: whose problem is it and how can intensivists help?Andrew F Shorr
Crit Care Med 35:299-301. 2007 - Prolonged acute mechanical ventilation, hospital resource utilization, and mortality in the United StatesMarya D Zilberberg
University of Massachusetts, School of Public Health and Health Sciences, Amherst, MA, USA
Crit Care Med 36:724-30. 2008..We compared the prevalence, characteristics, and outcomes of MV < 96 hrs (MV < 96) and prolonged acute MV (PAMV) of > or = 96 hrs' duration in a representative sample of U.S. hospital discharges...