James A Maclean
Affiliation: Southern Illinois University School of Medicine
- Maclean J, Hayashi K, Turner T, Wilkinson M. The Rhox5 homeobox gene regulates the region-specific expression of its paralogs in the rodent epididymis. Biol Reprod. 2012;86:189 pubmed publisher..Our results lead us to propose that widespread changes in the region-specific expression pattern of genes over evolutionary time can be the result of alterations of one or only a few master regulatory genes...
- Welborn J, Davis M, Ebers S, Stodden G, Hayashi K, Cheatwood J, et al. Rhox8 Ablation in the Sertoli Cells Using a Tissue-Specific RNAi Approach Results in Impaired Male Fertility in Mice. Biol Reprod. 2015;93:8 pubmed publisher..Taken together, our study underscores the importance of Rhox genes in male fertility and suggests that Sertoli cell-specific expression of Rhox5 and Rhox8 is critical for complete male fertility. ..