Species

James A Maclean

Summary

Affiliation: Southern Illinois University School of Medicine
Country: USA

Publications

  1. Maclean J, Hayashi K, Turner T, Wilkinson M. The Rhox5 homeobox gene regulates the region-specific expression of its paralogs in the rodent epididymis. Biol Reprod. 2012;86:189 pubmed publisher
    ..Our results lead us to propose that widespread changes in the region-specific expression pattern of genes over evolutionary time can be the result of alterations of one or only a few master regulatory genes...
  2. Welborn J, Davis M, Ebers S, Stodden G, Hayashi K, Cheatwood J, et al. Rhox8 Ablation in the Sertoli Cells Using a Tissue-Specific RNAi Approach Results in Impaired Male Fertility in Mice. Biol Reprod. 2015;93:8 pubmed publisher
    ..Taken together, our study underscores the importance of Rhox genes in male fertility and suggests that Sertoli cell-specific expression of Rhox5 and Rhox8 is critical for complete male fertility. ..

Detail Information

Publications2

  1. Maclean J, Hayashi K, Turner T, Wilkinson M. The Rhox5 homeobox gene regulates the region-specific expression of its paralogs in the rodent epididymis. Biol Reprod. 2012;86:189 pubmed publisher
    ..Our results lead us to propose that widespread changes in the region-specific expression pattern of genes over evolutionary time can be the result of alterations of one or only a few master regulatory genes...
  2. Welborn J, Davis M, Ebers S, Stodden G, Hayashi K, Cheatwood J, et al. Rhox8 Ablation in the Sertoli Cells Using a Tissue-Specific RNAi Approach Results in Impaired Male Fertility in Mice. Biol Reprod. 2015;93:8 pubmed publisher
    ..Taken together, our study underscores the importance of Rhox genes in male fertility and suggests that Sertoli cell-specific expression of Rhox5 and Rhox8 is critical for complete male fertility. ..