K Husain

Summary

Affiliation: Southern Illinois University School of Medicine
Country: USA

Publications

  1. ncbi request reprint Carboplatin-induced oxidative stress in rat cochlea
    K Husain
    Department of Pharmacology, Southern Illinois University School of Medicine, Springfield, 62794 9629, USA
    Hear Res 159:14-22. 2001
  2. ncbi request reprint Dose response of carboplatin-induced nephrotoxicity in rats
    Kazim Husai
    Department of Pharmacology, Southern Illinois University School of Medicine, Springfield 62794 9638, USA
    Pharmacol Toxicol 91:83-9. 2002
  3. ncbi request reprint Dose response of carboplatin-induced hearing loss in rats: antioxidant defense system
    K Husain
    Department of Pharmacology, Southern Illinois University School of Medicine, Springfield 62794 9629, USA
    Hear Res 151:71-78. 2001
  4. ncbi request reprint Oxidative injury due to chronic nitric oxide synthase inhibition in rat: effect of regular exercise on the heart
    Kazim Husain
    Department of Surgery, School of Medicine, Southern Illinois University, 800 North Rutledge St, Springfield, IL 62794 9638, USA
    Biochim Biophys Acta 1587:75-82. 2002
  5. ncbi request reprint Dose-dependent protection by lipoic acid against cisplatin-induced nephrotoxicity in rats: antioxidant defense system
    S M Somani
    Department of Pharmacology, Southern Illinois University School of Medicine, Springfield 62794 9629, USA
    Pharmacol Toxicol 86:234-41. 2000
  6. ncbi request reprint Interaction of pyridostigmine and physical stress on antioxidant defense system in skeletal muscle of mice
    R Jagannathan
    Department of Pharmacology, Southern Illinois University School of Medicine, Springfield, IL 62794-9269, USA
    J Appl Toxicol 21:341-8. 2001
  7. ncbi request reprint Chronic ethanol and nicotine interaction on rat tissue antioxidant defense system
    K Husain
    Department of Pharmacology, Southern Illinois University School of Medicine, Springfield, IL 62794-9629, USA
    Alcohol 25:89-97. 2001
  8. ncbi request reprint Response of the olfactory bulb antioxidant system following diethyldithiocarbamate (DDTC) administration in rats
    R G Struble
    Department of Neurology, Southern Illinois University School of Medicine, Springfield 62794, USA
    J Appl Toxicol 19:221-8. 1999
  9. ncbi request reprint Time response of carboplatin-induced hearing loss in rat
    K Husain
    Department of Surgery, Southern Illinois University School of Medicine, Springfield, IL 62794, USA
    Hear Res 191:110-8. 2004
  10. ncbi request reprint Interactive and delayed effects of pyridostigmine and physical stress on biochemical and histological changes in peripheral tissues of mice
    S M Somani
    Department of Pharmacology, Southern Illinois University School of Medicine, Springfield, IL 62794, USA
    J Appl Toxicol 20:327-34. 2000

Collaborators

  • S M Somani
  • R G Struble
  • Kazim Husai
  • R Jagannathan
  • Gary L Trammell
  • Ramesh Jagannathan
  • Zeshan Hasan
  • Stephen R Hazelrigg
  • Leonard P Rybak

Detail Information

Publications10

  1. ncbi request reprint Carboplatin-induced oxidative stress in rat cochlea
    K Husain
    Department of Pharmacology, Southern Illinois University School of Medicine, Springfield, 62794 9629, USA
    Hear Res 159:14-22. 2001
    ..The data suggest that carboplatin induced free radical generation and antioxidant depletion, and caused oxidative injury in the cochleae of rats...
  2. ncbi request reprint Dose response of carboplatin-induced nephrotoxicity in rats
    Kazim Husai
    Department of Pharmacology, Southern Illinois University School of Medicine, Springfield 62794 9638, USA
    Pharmacol Toxicol 91:83-9. 2002
    ..The data suggested that carboplatin caused dose-dependent oxidative renal injury, as evidenced by renal antioxidant depletion, enhanced lipid peroxidation, platinum content, plasma creatinine and blood urea nitrogen levels in rats...
  3. ncbi request reprint Dose response of carboplatin-induced hearing loss in rats: antioxidant defense system
    K Husain
    Department of Pharmacology, Southern Illinois University School of Medicine, Springfield 62794 9629, USA
    Hear Res 151:71-78. 2001
    ..The data suggest that higher doses of carboplatin (above 128 mg/kg) induce hearing loss as evidenced by significant changes in ABRs, lipid peroxidation and antioxidants in the cochlea of rats...
  4. ncbi request reprint Oxidative injury due to chronic nitric oxide synthase inhibition in rat: effect of regular exercise on the heart
    Kazim Husain
    Department of Surgery, School of Medicine, Southern Illinois University, 800 North Rutledge St, Springfield, IL 62794 9638, USA
    Biochim Biophys Acta 1587:75-82. 2002
    ..The data suggest that physical conditioning attenuated the oxidative injury caused by chronic NOS inhibition by up-regulating the cardiac antioxidant defense system and lowering the BP and HR in rats...
  5. ncbi request reprint Dose-dependent protection by lipoic acid against cisplatin-induced nephrotoxicity in rats: antioxidant defense system
    S M Somani
    Department of Pharmacology, Southern Illinois University School of Medicine, Springfield 62794 9629, USA
    Pharmacol Toxicol 86:234-41. 2000
    ....
  6. ncbi request reprint Interaction of pyridostigmine and physical stress on antioxidant defense system in skeletal muscle of mice
    R Jagannathan
    Department of Pharmacology, Southern Illinois University School of Medicine, Springfield, IL 62794-9269, USA
    J Appl Toxicol 21:341-8. 2001
    ..Physical stress amplified the delayed effects of PB in the skeletal muscle of mice...
  7. ncbi request reprint Chronic ethanol and nicotine interaction on rat tissue antioxidant defense system
    K Husain
    Department of Pharmacology, Southern Illinois University School of Medicine, Springfield, IL 62794-9629, USA
    Alcohol 25:89-97. 2001
    ..It is suggested that prolonged exposure to ethanol and nicotine produce similar, and in some cases additive, oxidative tissue injuries in rat...
  8. ncbi request reprint Response of the olfactory bulb antioxidant system following diethyldithiocarbamate (DDTC) administration in rats
    R G Struble
    Department of Neurology, Southern Illinois University School of Medicine, Springfield 62794, USA
    J Appl Toxicol 19:221-8. 1999
    ..These data suggest that increased ROS flux perturbs the olfactory bulb antioxidant defense system during olfactory nerve regeneration...
  9. ncbi request reprint Time response of carboplatin-induced hearing loss in rat
    K Husain
    Department of Surgery, Southern Illinois University School of Medicine, Springfield, IL 62794, USA
    Hear Res 191:110-8. 2004
    ..The data suggest that carboplatin-induced hearing loss involves oxidative injury to the cochlea of the rat in a time-dependent manner...
  10. ncbi request reprint Interactive and delayed effects of pyridostigmine and physical stress on biochemical and histological changes in peripheral tissues of mice
    S M Somani
    Department of Pharmacology, Southern Illinois University School of Medicine, Springfield, IL 62794, USA
    J Appl Toxicol 20:327-34. 2000
    ..These results indicate that physical stress enhanced the delayed toxic effects of a subchronic oral dose of pyridostigmine primarily in the skeletal muscle of mice...