Research Topics
Genomes and Genes | Robert HarrodSummaryAffiliation: Southern Methodist University Country: USA Publications
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Detail Information
Publications
A novel chimeric Rev, Tat, and Nef (Retanef) antigen as a component of an SIV/HIV vaccineZdenek Hel
Basic Research Laboratory, National Cancer Institute, 41 D804, Bethesda, MD 20892, USA
Vaccine 20:3171-86. 2002..No adverse effects were observed in either naive or SIV-infected rhesus macaques. Thus, an analogous HIV-1-based chimeric vaccine may represent useful component of an HIV-1 vaccine...
HIV-1 Tat interactions with p300 and PCAF transcriptional coactivators inhibit histone acetylation and neurotrophin signaling through CREBKasuen Wong
Laboratory of Molecular Virology, Department of Biological Sciences, Southern Methodist University, Dallas, Texas 75275 0376, USA
J Biol Chem 280:9390-9. 2005..Importantly, these findings suggest that HIV-1 Tat-coactivator interactions may contribute to neurotrophin signaling impairments and neuronal apoptosis associated with HIV-1 infections of the CNS...
A human T-cell lymphotropic virus type 1 enhancer of Myc transforming potential stabilizes Myc-TIP60 transcriptional interactionsSoumya Awasthi
Laboratory of Molecular Virology, Department of Biological Sciences, Southern Methodist University, 334 DLS, 6501 Airline Drive, Dallas, TX 75275 0376
Mol Cell Biol 25:6178-98. 2005..Importantly, these results suggest that p30II functions as a novel retroviral modulator of Myc-TIP60-transforming interactions that may contribute to adult T-cell leukemogenesis...
Human immunodeficiency virus type-1 Tat/co-activator acetyltransferase interactions inhibit p53Lys-320 acetylation and p53-responsive transcriptionRobert Harrod
Laboratory of Molecular Virology, Department of Biological Sciences, Southern Methodist University, Dallas, Texas 75275 0376, USA
J Biol Chem 278:12310-8. 2003..Our results allude to a mechanism whereby the human immunodeficiency virus type-1 trans-activator might impair tumor suppressor functions in immune/neuronal-derived cells, thus favoring the establishment of neoplasia during AIDS...
Nerve growth factor receptor signaling induces histone acetyltransferase domain-dependent nuclear translocation of p300/CREB-binding protein-associated factor and hGCN5 acetyltransferasesKasuen Wong
Laboratory of Molecular Virology, Department of Biological Sciences, Southern Methodist University, 6501 Airline Drive, Dallas, TX 75275 0376, USA
J Biol Chem 279:55667-74. 2004....
The Werner syndrome helicase is a cofactor for HIV-1 long terminal repeat transactivation and retroviral replicationAnima Sharma
Laboratory of Molecular Virology, Department of Biological Sciences, Southern Methodist University, Dallas, Texas 75275 0376, USA
J Biol Chem 282:12048-57. 2007..WRN may be a plausible target for antiretroviral therapy...
Transcriptional regulation of the bovine leukemia virus promoter by the cyclic AMP-response element modulator tau isoformThi Lien Anh Nguyen
Institut de Biologie et de Médecine Moléculaires, Laboratoire de Virologie Moleculaire, Universite Libre de Bruxelles, Rue des Profs Jeener et Brachet 12, 6041 Gosselies, Belgium
J Biol Chem 282:20854-67. 2007....
