John W Cole
Affiliation: Southern Iron Disorders Center
- Acquired immunodeficiency syndrome and the risk of strokeJohn W Cole
Department of Neurology, University of Maryland, Baltimore 21201, USA
Stroke 35:51-6. 2004..Although acquired immunodeficiency syndrome (AIDS) is thought to increase the risk of stroke, few data exist to quantify this risk. This is the first population-based study to quantify the AIDS-associated risk of stroke...
- Factor V leiden and ischemic stroke risk: the Genetics of Early Onset Stroke (GEOS) studyAli G Hamedani
Department of Neurology, University of Maryland School of Medicine, Baltimore, Maryland 21201 1509, USA
J Stroke Cerebrovasc Dis 22:419-23. 2013..Therefore, we examined the association between FVL and ischemic stroke in participants of the Genetics of Early Onset Stroke (GEOS) study...
- Dose-response relationship between cigarette smoking and risk of ischemic stroke in young womenViveca M Bhat
Department of Neurology, Room 12 006, University of Maryland, Baltimore, 655 W Baltimore St, Baltimore, MD 21201, USA
Stroke 39:2439-43. 2008..Although cigarette smoking is known to be a risk factor for ischemic stroke, there are few data on the dose-response relationship between smoking and stroke risk in a young ethnically diverse population...
- Frequency of unrecognized Fabry disease among young European-American and African-American men with first ischemic strokeMarcella A Wozniak
Department of Neurology, 22 South Greene Street, Baltimore, MD 21201, USA
Stroke 41:78-81. 2010..A European study suggested an increased prevalence of unrecognized Fabry disease in patients with cryptogenic stroke. We hypothesized that alpha-Gal A deficiency is a rare cause of initial early-onset ischemic stroke in men...
- Familial aggregation of ischemic stroke in young women: the Stroke Prevention in Young Women StudyLeah R MacClellan
Department of Epidemiology and Preventive Medicine, School of Medicine, University of Maryland, Baltimore, MD, USA
Genet Epidemiol 30:602-8. 2006..To address this issue, we compared the frequency of stroke in relatives of stroke cases to that in relatives of controls across different ages and by stroke subtype...
- Evaluation of self-reported ethnicity in a case-control population: the stroke prevention in young women studyJesse B Mez
Department of Neurology, University of Maryland School of Medicine, Baltimore, MD, USA
BMC Res Notes 2:260. 2009..Here we apply a model-based clustering approach to our case-control study of stroke among young women to examine if self-reported ethnicity can serve as a proxy for genetic ancestry...
- Meta-analysis of factor V Leiden and ischemic stroke in young adults: the importance of case ascertainmentAli G Hamedani
Department of Neurology, University of Maryland School of Medicine, Baltimore, MD 21201 1509, USA
Stroke 41:1599-603. 2010..The factor V Leiden mutation is associated with ischemic stroke in children but not in adults. Whether it is associated with ischemic stroke in young adults, however, is uncertain...
- Smoking and stroke: the more you smoke the more you strokeReena S Shah
Department of Neurology, University of Maryland School of Medicine, 110 South Paca Street, Third Floor, Baltimore, MD 21201 1559, USA
Expert Rev Cardiovasc Ther 8:917-32. 2010..In this article, we summarize the literature regarding smoking-related stroke risk, the dose-response relationship, and the costs of this detrimental habit to both the individual and society as a whole...
- Do common infections cause stroke?Mitchell S V Elkind
Department of Neurology, Gertrude H Sergievsky Center, Columbia University, New York Presbyterian Hospital, NY 10032, USA
Semin Neurol 26:88-99. 2006....
- Thrombomodulin Ala455Val Polymorphism and the risk of cerebral infarction in a biracial population: the Stroke Prevention in Young Women StudyJohn W Cole
Department of Neurology, University of Maryland School of Medicine, Baltimore, Maryland, USA
BMC Neurol 4:21. 2004..Using data from the Stroke Prevention in Young Women Study, we sought to determine the association between the Ala455Val thrombomodulin polymorphism and the occurrence of ischemic stroke in young women...
- Promoter polymorphisms in the nitric oxide synthase 3 gene are associated with ischemic stroke susceptibility in young black womenTimothy D Howard
The Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, NC, USA
Stroke 36:1848-51. 2005..Endothelial nitric oxide exerts a variety of protective effects on endothelial cells and blood vessels, and therefore the nitric oxide synthase 3 gene (NOS3) is a logical candidate gene for stroke susceptibility...
- Preeclampsia and the risk of ischemic stroke among young women: results from the Stroke Prevention in Young Women StudyDavid W Brown
Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Stroke 37:1055-9. 2006..Although preeclampsia is known to be an important risk factor for pregnancy-associated stroke, few data exist with regard to its association with stroke not occurring during pregnancy or the postpartum period...
- Phosphodiesterase 4D polymorphisms and the risk of cerebral infarction in a biracial population: the Stroke Prevention in Young Women StudyQing Song
Morehouse School of Medicine, Atlanta, GA 30314, USA
Hum Mol Genet 15:2468-78. 2006..9, P=0.75) or former smokers (OR=1.2, P=0.66), demonstrating a gene-environment interaction (P=0.03). A strong dose-response relationship was also seen among current smokers. No specific risk haplotypes were identified...
- Neuroserpin polymorphisms and stroke risk in a biracial population: the stroke prevention in young women studyJohn W Cole
Veterans Affairs Medical Center, Baltimore, Maryland, USA
BMC Neurol 7:37. 2007..We sought to evaluate the association of neuroserpin polymorphisms with risk for ischemic stroke among young women...