Yong Kyu Chu

Summary

Affiliation: Southern Research Institute
Country: USA

Publications

  1. pmc Phylogenetic and geographical relationships of hantavirus strains in eastern and western Paraguay
    Yong Kyu Chu
    Emerging Infectious Disease Program, Department of Biochemistry and Molecular Biology, Southern Research Institute, Birmingham, AL 35205, USA
    Am J Trop Med Hyg 75:1127-34. 2006
  2. pmc Activity of ribavirin against Hantaan virus correlates with production of ribavirin-5'-triphosphate, not with inhibition of IMP dehydrogenase
    Yanjie Sun
    Southern Research Institute, 2000 Ninth Avenue South, Birmingham, AL 35205, USA
    Antimicrob Agents Chemother 51:84-8. 2007
  3. ncbi request reprint Genetic characterization and phylogeny of a hantavirus from Western Mexico
    Yong Kyu Chu
    Emerging Infectious Disease Research Program, Department of Biochemistry and Molecular Biology, Southern Research Institute, 2000 Ninth Avenue S, Birmingham, AL 35255 5305, USA
    Virus Res 131:180-8. 2008
  4. pmc Dynein-dependent transport of the hantaan virus nucleocapsid protein to the endoplasmic reticulum-Golgi intermediate compartment
    Harish N Ramanathan
    Graduate Program in Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    J Virol 81:8634-47. 2007
  5. pmc Sympatry of 2 hantavirus strains, paraguay, 2003-2007
    Yong Kyu Chu
    Southern Research Institute, Birmingham, Alabama, USA
    Emerg Infect Dis 15:1977-80. 2009
  6. pmc The SARS-CoV ferret model in an infection-challenge study
    Yong Kyu Chu
    Department of Biochemistry and Molecular Biology, Southern Research Institute, Birmingham, AL, USA
    Virology 374:151-63. 2008
  7. pmc Synthesis of 1-beta-D-ribofuranosyl-3-ethynyl-[1,2,4]triazole and its in vitro and in vivo efficacy against Hantavirus
    DONG HOON CHUNG
    Department of Biochemistry and Molecular Biology, Southern Research Institute, Birmingham, AL 35205, USA
    Antiviral Res 79:19-27. 2008

Collaborators

Detail Information

Publications7

  1. pmc Phylogenetic and geographical relationships of hantavirus strains in eastern and western Paraguay
    Yong Kyu Chu
    Emerging Infectious Disease Program, Department of Biochemistry and Molecular Biology, Southern Research Institute, Birmingham, AL 35205, USA
    Am J Trop Med Hyg 75:1127-34. 2006
    ..AAI was found in areas experiencing rapid land cover fragmentation and change within the Interior Atlantic Forest. IP37/38 did not show any strong association with any of the known hantavirus strains...
  2. pmc Activity of ribavirin against Hantaan virus correlates with production of ribavirin-5'-triphosphate, not with inhibition of IMP dehydrogenase
    Yanjie Sun
    Southern Research Institute, 2000 Ninth Avenue South, Birmingham, AL 35205, USA
    Antimicrob Agents Chemother 51:84-8. 2007
    ..These results suggest that the inhibition of IMP dehydrogenase by RBV is of secondary importance to the inhibition of vRNA replication by RBV and that the interaction of RBV-TP with the viral polymerase is the primary action of RBV...
  3. ncbi request reprint Genetic characterization and phylogeny of a hantavirus from Western Mexico
    Yong Kyu Chu
    Emerging Infectious Disease Research Program, Department of Biochemistry and Molecular Biology, Southern Research Institute, 2000 Ninth Avenue S, Birmingham, AL 35255 5305, USA
    Virus Res 131:180-8. 2008
    ..This and phylogenetic analysis of the M and S segments suggests that ORO virus is a unique genotype within Hantavirus...
  4. pmc Dynein-dependent transport of the hantaan virus nucleocapsid protein to the endoplasmic reticulum-Golgi intermediate compartment
    Harish N Ramanathan
    Graduate Program in Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    J Virol 81:8634-47. 2007
    ....
  5. pmc Sympatry of 2 hantavirus strains, paraguay, 2003-2007
    Yong Kyu Chu
    Southern Research Institute, Birmingham, Alabama, USA
    Emerg Infect Dis 15:1977-80. 2009
    ..We detected Jabora virus and Itapua37/Juquitiba-related virus in locations approximately 20 m apart in different years, which suggested sympatry of 2 distinct hantaviruses...
  6. pmc The SARS-CoV ferret model in an infection-challenge study
    Yong Kyu Chu
    Department of Biochemistry and Molecular Biology, Southern Research Institute, Birmingham, AL, USA
    Virology 374:151-63. 2008
    ..This study supports the validity of the ferret model for use in evaluating efficacy of potential therapeutics to treat SARS...
  7. pmc Synthesis of 1-beta-D-ribofuranosyl-3-ethynyl-[1,2,4]triazole and its in vitro and in vivo efficacy against Hantavirus
    DONG HOON CHUNG
    Department of Biochemistry and Molecular Biology, Southern Research Institute, Birmingham, AL 35205, USA
    Antiviral Res 79:19-27. 2008
    ..ETAR is an exciting and promising lead compound that will be elaborated in further synthetic investigations as a framework for the rational design of new antivirals for treatment of HFRS...