Hongwei Zhang

Summary

Affiliation: South Dakota State University
Country: USA

Publications

  1. ncbi Several rAAV vectors efficiently cross the blood-brain barrier and transduce neurons and astrocytes in the neonatal mouse central nervous system
    Hongwei Zhang
    Gene Therapy Center, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Mol Ther 19:1440-8. 2011
  2. ncbi MicroRNA-regulated, systemically delivered rAAV9: a step closer to CNS-restricted transgene expression
    Jun Xie
    Gene Therapy Center, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Mol Ther 19:526-35. 2011
  3. ncbi Long-term, efficient inhibition of microRNA function in mice using rAAV vectors
    Jun Xie
    Gene Therapy Center, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Nat Methods 9:403-9. 2012
  4. ncbi Adenovirus-adeno-associated virus hybrid for large-scale recombinant adeno-associated virus production
    Hongwei Zhang
    Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Hum Gene Ther 20:922-9. 2009

Collaborators

Detail Information

Publications4

  1. ncbi Several rAAV vectors efficiently cross the blood-brain barrier and transduce neurons and astrocytes in the neonatal mouse central nervous system
    Hongwei Zhang
    Gene Therapy Center, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Mol Ther 19:1440-8. 2011
    ....
  2. ncbi MicroRNA-regulated, systemically delivered rAAV9: a step closer to CNS-restricted transgene expression
    Jun Xie
    Gene Therapy Center, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Mol Ther 19:526-35. 2011
    ..Our findings promise to facilitate the development of miRNA-regulated rAAV for CNS-targeted gene delivery and other applications...
  3. ncbi Long-term, efficient inhibition of microRNA function in mice using rAAV vectors
    Jun Xie
    Gene Therapy Center, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Nat Methods 9:403-9. 2012
    ..rAAV-mediated miRNA inhibition thus provides a simple way to study miRNA function in adult mammals and a potential therapy for dyslipidemia and other diseases caused by miRNA deregulation...
  4. ncbi Adenovirus-adeno-associated virus hybrid for large-scale recombinant adeno-associated virus production
    Hongwei Zhang
    Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Hum Gene Ther 20:922-9. 2009
    ..This minireview provides an overview of this scaleable rAAV production platform, describing its basic components and biological mechanisms and process...