SRINATH PALAKURTHI

Summary

Affiliation: South Dakota State University
Country: USA

Publications

  1. ncbi Screening of 14C-polyamines in the AT3B-1 rat prostate tumor model: the search for a new PET prostate imaging agent
    S Palakurthi
    College of Pharmacy, South Dakota State University, Brookings, SD, 57007 0099, USA
    In Vivo 21:823-8. 2007
  2. ncbi Target specificity of 188Re-labeled B27.1 monoclonal antibodies to ovarian cancer cells in vivo
    SRINATH PALAKURTHI
    Department of Pharmaceutical Sciences, College of Pharmacy, South Dakota State University, Brookings, SD 57007, USA
    In Vivo 22:321-6. 2008
  3. ncbi Mechanism of gene transfection by polyamidoamine (PAMAM) dendrimers modified with ornithine residues
    Ajay Kumar
    Department of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A and M Health Science Center, Kingsville, TX, USA
    J Drug Target 19:770-80. 2011
  4. ncbi Biotinylated PAMAM dendrimers for intracellular delivery of cisplatin to ovarian cancer: role of SMVT
    Venkata K Yellepeddi
    Department of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A and M Health Science Center, 1010 W Ave B, Kingsville, TX, 78363, USA
    Anticancer Res 31:897-906. 2011
  5. ncbi Transport of surface engineered polyamidoamine (PAMAM) dendrimers across IPEC-J2 cell monolayers
    Dipak S Pisal
    Department of Pharmaceutical Sciences, College of Pharmacy, South Dakota State University, Brookings, South Dakota 57007, USA
    Drug Deliv 15:515-22. 2008
  6. ncbi Enhanced gene transfection efficiency by polyamidoamine (PAMAM) dendrimers modified with ornithine residues
    Ajay Kumar
    Department of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A and M Health Science Center, Kingsville, TX 78363, USA
    Int J Pharm 392:294-303. 2010
  7. ncbi Biodisposition of PEG-coated lipid microspheres of indomethacin in arthritic rats
    S Palakurthi
    College of Pharmacy, South Dakota State University, Brookings, SD 57007, USA
    Int J Pharm 290:55-62. 2005
  8. ncbi Surface modified poly(amido)amine dendrimers as diverse nanomolecules for biomedical applications
    Venkata K Yellepeddi
    Irma Lerma Rangel College of Pharmacy, Texas A and M Health Science Center, Department of Pharmaceutical Sciences, Kingsville, TX 78363, USA
    Expert Opin Drug Deliv 6:835-50. 2009
  9. ncbi Biotinylated poly(amido)amine (PAMAM) dendrimers as carriers for drug delivery to ovarian cancer cells in vitro
    Venkata K Yellepeddi
    Department of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A and M Health Science Center, Kingsville, TX 78363, USA
    Anticancer Res 29:2933-43. 2009
  10. ncbi Permeability of surface-modified polyamidoamine (PAMAM) dendrimers across Caco-2 cell monolayers
    Dipak S Pisal
    Department of Pharmaceutical Sciences, South Dakota State University, Brookings, SD 57007, USA
    Int J Pharm 350:113-21. 2008

Research Grants

  1. Novel Polyamine-conjugated Dendrimers for Pretargeted Chemotherapy of Ovarian Can
    SRINATH PALAKURTHI; Fiscal Year: 2006

Collaborators

Detail Information

Publications10

  1. ncbi Screening of 14C-polyamines in the AT3B-1 rat prostate tumor model: the search for a new PET prostate imaging agent
    S Palakurthi
    College of Pharmacy, South Dakota State University, Brookings, SD, 57007 0099, USA
    In Vivo 21:823-8. 2007
    ..The objective of the present study was to assess their in vivo accumulation in a rat prostate tumor model...
  2. ncbi Target specificity of 188Re-labeled B27.1 monoclonal antibodies to ovarian cancer cells in vivo
    SRINATH PALAKURTHI
    Department of Pharmaceutical Sciences, College of Pharmacy, South Dakota State University, Brookings, SD 57007, USA
    In Vivo 22:321-6. 2008
    ..As a preliminary step to realize this goal, we determined the target specificity of the monoclonal antibodies (B27.1) to the ovarian cancer cells in vivo...
  3. ncbi Mechanism of gene transfection by polyamidoamine (PAMAM) dendrimers modified with ornithine residues
    Ajay Kumar
    Department of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A and M Health Science Center, Kingsville, TX, USA
    J Drug Target 19:770-80. 2011
    ..Cytotoxicity analysis (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide (MTT) assay) in human embryonic kidney cell line (HEK) 293T cells showed that the dendriplexes were non-toxic at N/P 10...
  4. ncbi Biotinylated PAMAM dendrimers for intracellular delivery of cisplatin to ovarian cancer: role of SMVT
    Venkata K Yellepeddi
    Department of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A and M Health Science Center, 1010 W Ave B, Kingsville, TX, 78363, USA
    Anticancer Res 31:897-906. 2011
    ..The aim of this study was to prepare biotinylated PAMAM dendrimers loaded with cisplatin and to evaluate the cytotoxicity in ovarian cancer cell lines...
  5. ncbi Transport of surface engineered polyamidoamine (PAMAM) dendrimers across IPEC-J2 cell monolayers
    Dipak S Pisal
    Department of Pharmaceutical Sciences, College of Pharmacy, South Dakota State University, Brookings, South Dakota 57007, USA
    Drug Deliv 15:515-22. 2008
    ....
  6. ncbi Enhanced gene transfection efficiency by polyamidoamine (PAMAM) dendrimers modified with ornithine residues
    Ajay Kumar
    Department of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A and M Health Science Center, Kingsville, TX 78363, USA
    Int J Pharm 392:294-303. 2010
    ..Cytotoxicity assay has shown that PAMAMG4-ORN60 dendriplexes at N/P 10 were safe at concentrations <or=50 microg/mL. It may be concluded that the ornithine-conjugated dendrimers possess the potential to be novel gene carrier...
  7. ncbi Biodisposition of PEG-coated lipid microspheres of indomethacin in arthritic rats
    S Palakurthi
    College of Pharmacy, South Dakota State University, Brookings, SD 57007, USA
    Int J Pharm 290:55-62. 2005
    ..The high accumulation of the drug in arthritic paw with S-LM system may be accounted for by the reduced uptake by RES cells, and thereby, availability for extravascularization in the inflammatory tissues...
  8. ncbi Surface modified poly(amido)amine dendrimers as diverse nanomolecules for biomedical applications
    Venkata K Yellepeddi
    Irma Lerma Rangel College of Pharmacy, Texas A and M Health Science Center, Department of Pharmaceutical Sciences, Kingsville, TX 78363, USA
    Expert Opin Drug Deliv 6:835-50. 2009
    ....
  9. ncbi Biotinylated poly(amido)amine (PAMAM) dendrimers as carriers for drug delivery to ovarian cancer cells in vitro
    Venkata K Yellepeddi
    Department of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A and M Health Science Center, Kingsville, TX 78363, USA
    Anticancer Res 29:2933-43. 2009
    ..We hypothesized that the synthesis of poly (amido)amine (PAMAM) dendrimers with biotin molecules might contribute to enhanced cancer cell-specific uptake...
  10. ncbi Permeability of surface-modified polyamidoamine (PAMAM) dendrimers across Caco-2 cell monolayers
    Dipak S Pisal
    Department of Pharmaceutical Sciences, South Dakota State University, Brookings, SD 57007, USA
    Int J Pharm 350:113-21. 2008
    ....

Research Grants1

  1. Novel Polyamine-conjugated Dendrimers for Pretargeted Chemotherapy of Ovarian Can
    SRINATH PALAKURTHI; Fiscal Year: 2006
    ..This novel approach reduces the toxic side effects associated with the chemotherapeutics used for the ovarian cancer treatment. ..