Anthony C Soldano

..Dermatopathologists should consider OFMT in the differential diagnosis of subcutaneous neoplasms with a myxoid matrix...

..Amalgam tattoos can either be treated surgically or with a Q-switched ruby laser. In the case of our patient with the history of melanoma, her oral lesions proved not to be the more dire diagnosis of malignant melanoma...

..This case highlights the importance of considering both histopathologic and clinical criteria in diagnosing a patient with a CD30+ cutaneous lymphoma...

..Focal or diffuse mucinous deposits are seen on histopathologic examination. The usual clinical course is slow cutaneous progression without spontaneous resolution. Treatment is empiric and is usually unsuccessful...

..After 4 months of acitretin 25 mg per day, our patient experienced near complete clearance of her skin lesions...

..These include electrodesiccation, excision, trichloracetic acid, carbon-dioxide laser, and 1450-nm diode laser...

..The treatment is limited, and only a few reported cases have shown remission after stopping dialysis in transient renal failure...

....

..The physical examination and histopathologic findings are consistent with a diagnosis of hereditary papulotranslucent acrokeratoderma...

..Two additional biopsy specimens from her forehead showed one invasive and one in-situ squamous-cell carcinoma. Both biopsy specimens demonstrated histopathologic evidence of epidermodysplasia verruciformis...

..As this is a diagnosis of exclusion, other etiologies of granulomatous inflammation must be ruled out with tests and special stains. The mainstay of treatment is with oral glucocorticoids...

..Although solitary fibrous tumors in cutaneous and subcutaneous regions are extremely rare, it should be considered in the differential diagnosis of primary spindle cell neoplasms of the skin...

..Therefore, even with a biopsy-proven diagnosis, the clinician must always monitor lesions of the nail unit for appropriate response to treatment and consider an additional biopsy for recalcitrant lesions...

..Histopathologic examination demonstrated interface dermatitis with epidermal atrophy. A diagnosis of oral lichen planus was made based on clinicopathologic correlation, and treatment with topical tacrolimus ointment was initiated...