- Antithrombotic therapy for peripheral artery occlusive disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)Michael Sobel
VA Puget Sound Health Care System and University of Washihngton School of Medicine, 1660 South Columbian Way, Seattle, WA 98108 1597, USA
Chest 133:815S-843S. 2008..For all patients undergoing lower-extremity balloon angioplasty (with or without stenting), we recommend long-term aspirin, 75-100 mg/d (Grade 1C)...
- Heparin-II domain of fibronectin is a vascular endothelial growth factor-binding domain: enhancement of VEGF biological activity by a singular growth factor/matrix protein synergismErrol S Wijelath
Department of Surgery, Division of Vascular Surgery, Veterans Affairs Puget Sound Health Care System and the University of Washington School of Medicine, Seattle, USA
Circ Res 99:853-60. 2006..These data also highlight a new function for the Fn C-terminal heparin-binding domain that may have important implications for angiogenesis and tumor growth...
- Antithrombotic therapy in peripheral arterial occlusive disease: the Seventh ACCP Conference on Antithrombotic and Thrombolytic TherapyG Patrick Clagett
Division of Vascular Surgery, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75235 9157, USA
Chest 126:609S-626S. 2004..In nonoperative patients with asymptomatic or recurrent carotid stenosis, we recommend lifelong aspirin (Grade 1C+). For all patients undergoing extremity balloon angioplasty, we recommend long-term aspirin (Grade 1C+)...
- Anticoagulants: to bleed or not to bleed, that is the questionMonica S Da Silva
SUNY Upstate Medical University, Syracuse, NY, USA
Semin Vasc Surg 15:256-67. 2002..Every interference with the coagulation cascade carries a risk of minor, major, or fatal hemorrhage. To date, no drug or therapeutic strategy has succeeded fully in dissociating its antithrombotic effects from its risks of bleeding...
- Heparin modulates integrin-mediated cellular adhesion: specificity of interactions with alpha and beta integrin subunitsMonica S Da Silva
Department of Surgery, SUNY Upstate Medical University and Veteran Affairs Medical Center, Syracuse, NY, USA
Cell Commun Adhes 10:59-67. 2003..The inhibitory or stimulatory effects of heparin depend on the beta subunit type, and the potency is dictated by structural characteristics of the glycosaminoglycan...
- Immobilization and clustering of structurally defined oligosaccharides for sugar chips: an improved method for surface plasmon resonance analysis of protein-carbohydrate interactionsYasuo Suda
Department of Nanostructure and Advanced Materials, Graduate School of Science and Engineering and Venture Business Laboratory, Kagoshima University, Kohrimoto, Kagoshima 890 0065, Japan
Bioconjug Chem 17:1125-35. 2006..This novel technique for oligosaccharide immobilization in SPR studies is accurate, specific, and easily applicable to both synthetic and naturally derived oligosaccharides...
- Sugar Chips immobilized with synthetic sulfated disaccharides of heparin/heparan sulfate partial structureMasahiro Wakao
Department of Nanostructure and Advanced Materials, Graduate School of Science and Engineering, Kagoshima University, 1 21 40 Korimoto, Kagoshima 890 0065, Japan
Bioorg Med Chem Lett 18:2499-504. 2008....
- Modulating Endothelialization of Cardiovascular GraftsMichael Sobel; Fiscal Year: 2007..In an animal model of peripheral artery bypass grafting that closely resembles the human condition, we will test these constructs and cells for their ability to promote the growth of a stable endothelial lining. ..
- PLATELET/HEPARIN INTERACTIONS IN CARDIOVASCULAR SURGERYMichael Sobel; Fiscal Year: 2003..abstract_text> ..
- PLATELET/HEPARIN INTERACTIONS IN CARDIOVASCULAR SURGERYMichael Sobel; Fiscal Year: 1999..In the future, the results of this work should provide research tools and insights useful for explorations of heparin's interactions with other adhesive proteins, vascular growth factors, and smooth muscle cells. ..