S A Williams
Affiliation: Smith College
- The filarial genome project: analysis of the nuclear, mitochondrial and endosymbiont genomes of Brugia malayiS A Williams
Filarial Genome Project Resource Center, Department of Biological Sciences, Smith College, Northampton, MA 01063, USA
Int J Parasitol 30:411-9. 2000....
- Deep within the filarial genome: progress of the filarial genome projectS A Williams
Department of Biological Sciences, Clark Science Center, Smith College, Northampton, MA 01063, USA
Parasitol Today 15:219-24. 1999..In this article, the principal investigators in the laboratories behind the project describe the background to the project, the data now emerging and goals for the future. Open access to filarial genome data is emphasized...
- Development and standardization of a rapid, PCR-based method for the detection of Wuchereria bancrofti in mosquitoes, for xenomonitoring the human prevalence of bancroftian filariasisS A Williams
Clark Science Center, Smith College, Northampton, MA 01063, USA
Ann Trop Med Parasitol 96:S41-6. 2002..Two of the four methods stood out as clearly the best and these will be now optimised and evaluated in two further rounds of testing...
- Development of a quantitative, competitive polymerase chain reaction--enzyme-linked immunosorbent assay for the detection of Wuchereria bancrofti DNAP Fischer
Department of Biological Sciences, Smith College, Northampton, MA 01063, USA
Parasitol Res 85:176-83. 1999..However, we present data indicating that the W. bancrofti QC-PCR-ELISA is a powerful new tool for evaluation of parasitic loads for community-based diagnosis of bancroftian filariasis...
- A rapid DNA assay for the species-specific detection and quantification of Brugia in blood samplesC B Poole
Department of Biological Sciences, Smith College, Northampton, MA 01063
Mol Biochem Parasitol 40:129-36. 1990..The assay was evaluated in a mock field study using Brugia malayi-infected jirds and was found to be an efficient and accurate method for quantifying microfilariae in blood samples...
- Detection of the filarial parasite Mansonella streptocerca in skin biopsies by a nested polymerase chain reaction-based assayP Fischer
Department of Biological Sciences, Smith College, Northampton, Massachusetts 01063, USA
Am J Trop Med Hyg 58:816-20. 1998..Control skin samples from patients infected with O. volvulus were all negative in the nested PCR assay. This assay improves the diagnosis of M. streptocerca and will facilitate further epidemiologic studies...
- Species-specific oligonucleotide probes for the identification of human filarial parasitesS A Williams
Department of Biological Sciences, Smith College, Northampton, MA 01060
Mol Biochem Parasitol 28:163-9. 1988..The B. pahangi probe has similar specificity and sensitivity for B. pahangi DNA. A rapid lysis procedure allows the probes to detect 1-2 third stage larvae of either B. malayi or B. pahangi in a filter hybridization assay...
- Seroprevalence of dengue in Trinidad using rapid test kits: a cord blood surveyC A Campbell
Department of Biology, Smith College, Northampton, MA, USA
Acta Trop 101:153-8. 2007..The high seroprevalence rates observed in Trinidad are discussed to stimulate more research to explain this phenomenon and to prevent the Southeast Asian scenario from developing in the Americas...
- Quantification of PCR amplification products of Brugia HhaI repeat DNA using a semiautomated Q-PCR systemU R Rao
Department of Microbiology and Parasitology, School of Veterinary Medicine, Louisiana State University, Baton Rouge, USA
Mol Cell Probes 16:13-23. 2002....
- Xenomonitoring of Culex quinquefasciatus mosquitoes as a guide for detecting the presence or absence of lymphatic filariasis: a preliminary protocol for mosquito samplingD D Chadee
Insect Vector Control Division, 3 Queen Street, St Joseph, Trinidad
Ann Trop Med Parasitol 96:S47-53. 2002..Data from the pilot study indicate that this xenomonitoring protocol may be applicable worldwide, albeit with modifications to take account of variations in the vector species involved and their ecology and resting behaviour...