Research Topics
| Ian R JowseySummaryAffiliation: Smith and Nephew Country: USA Publications
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Detail Information
Publications
Proliferative responses in the local lymph node assay associated with concomitant exposure to 1,4-phenylenediamine and methyldibromo glutaronitrile: evidence for synergy?Ian R Jowsey
Unilever Safety and Environmental Assurance Centre, Colworth Park, Sharnbrook, Bedfordshire, MK44 1LQ, UK
Contact Dermatitis 59:90-5. 2008..A key consideration when undertaking risk assessments should be the potential for synergy between contact allergens. Previously, this concept has only been investigated during elicitation in contact allergic individuals...- The impact of vehicle on the relative potency of skin-sensitizing chemicals in the local lymph node assayIan R Jowsey
Unilever Safety and Environmental Assurance Centre, Colworth Park, Sharnbrook, Bedfordshire, UK
Cutan Ocul Toxicol 27:67-75. 2008..These data underscore the need to consider vehicle effects in the context of skin-sensitization risk assessments... 
Preservatives and skin sensitization quantitative risk assessmentDavid A Basketter
Unilever, Colworth House, Sharnbrook, Bedfordshire, UK
Dermatitis 19:20-7. 2008....- Elicitation response characteristics to permanent hair dye in paraphenylenediamine-allergic volunteersIan R Jowsey
Unilever Safety and Environmental Assurance Centre, Colworth Park, Sharnbrook, Bedfordshire MK44 1LQ, UK
Contact Dermatitis 55:330-4. 2006..Elicitation response characteristics to complete permanent hair dye products in paraphenylenediamine (PPD)-allergic volunteers have not previously been explored in detail... - A future approach to measuring relative skin sensitising potency: a proposalIan R Jowsey
Unilever Safety and Environmental Assurance Centre, Sharnbrook, Bedfordshire, UK
J Appl Toxicol 26:341-50. 2006.... - Evidence that two alkyl ester quaternary ammonium compounds lack substantial human skin-sensitizing potentialIan R Jowsey
Unilever Safety and Environmental Assurance Centre, Colworth Park, Sharnbrook, Bedforshire, UK
Dermatitis 18:32-9. 2007..It is important to document in the literature the outcome of historical studies that were performed to assess the risk of adverse skin effects associated with their use... - The skin sensitization potential of resorcinol: experience with the local lymph node assayDavid A Basketter
Safety and Environmental Assurance Centre, Unilever, Colworth Park, Sharnbrook, Bedfordshire MK44 1LQ, UK
Contact Dermatitis 56:196-200. 2007..These data show the importance of adherence to test guidelines and aligns the clinical experience with resorcinol with that obtained in predictive animal methods... - Proactive surveillance of contact allergies: an important component of the risk management strategy for skin sensitizersIan R Jowsey
Unilever Safety and Environmental Assurance Centre, Colworth Park, Sharnbrook, Bedfordshire MK44 1LQ, UK
Contact Dermatitis 56:305-10. 2007..It is hoped that such a framework might further improve the efficacy of future approaches to skin sensitization risk assessment... - The impact of exposure variables on the induction of skin sensitizationDavid A Basketter
Safety and Environmental Assurance Centre, Unilever Colworth, Sharnbrook, Bedfordshire MK44 1PR, UK
Contact Dermatitis 55:178-85. 2006..Detailed statistical analysis of the results indicated that the most important factor driving the induction of skin sensitization was the number of exposures... - Oral tolerance to contact allergens: a common occurrence? A reviewJonathan M L White
Department of Cutaneous Allergy, St John s Institute of Dermatology, St Thomas Hospital, London SE1 7EH, UK
Contact Dermatitis 56:247-54. 2007..Existing data on formaldehyde may conflict with this theory, though this could be explained by allergen specificity. We propose that further work in this area is needed... - The biocide polyhexamethylene biguanide remains an uncommon contact allergenAxel Schnuch
Information Network of Departments of Dermatology IVDK, University of Gottingen, Germany
Contact Dermatitis 56:235-9. 2007..Further risk factors included leg dermatitis and old age. The frequency of sensitization remains low. It is very unlikely that exposure to cosmetics or personal care products may have played a role in the few cases sensitized...