D J Smith

Summary

Country: USA

Publications

  1. ncbi Stereochemical composition of clenbuterol residues in edible tissues of swine
    D J Smith
    Biosciences Research Laboratory, Agricultural Research Service, U S Department of Agriculture, P O Box 5674, University Station, Fargo, North Dakota 58105, USA
    J Agric Food Chem 48:6036-43. 2000
  2. ncbi Pharmacokinetics of ruminally dosed sodium [36Cl]chlorate in beef cattle
    C E Oliver
    Department of Animal and Range Sciences, North Dakota State University, Fargo, ND, USA
    J Vet Pharmacol Ther 30:358-65. 2007
  3. ncbi Development of an immunoassay for the beta-adrenergic agonist ractopamine
    W L Shelver
    US Department of Agriculture, Biosciences Research Laboratory, University Station, Fargo, ND 58105 5674, USA
    J Immunoassay 21:1-23. 2000
  4. ncbi Effect of sodium [36Cl]chlorate dose on total radioactive residues and residues of parent chlorate in growing swine
    D J Smith
    Biosciences Research Laboratory, Agricultural Research Service, U S Department of Agriculture, Fargo, North Dakota 58105 5674, USA
    J Agric Food Chem 54:8648-53. 2006
  5. ncbi Total radioactive residues and clenbuterol residues in swine after dietary administration of [14C]clenbuterol for seven days and preslaughter withdrawal periods of zero, three, or seven days
    D J Smith
    USDA ARS, Biosciences Research Laboratory, Fargo, ND 58105 5674, USA
    J Anim Sci 78:2903-12. 2000
  6. ncbi Response of C2C12 mouse and turkey skeletal muscle cells to the beta-adrenergic agonist ractopamine
    N W Shappell
    Biosciences Research Laboratory, ARS, USDA, Fargo, NS 58105, USA
    J Anim Sci 78:699-708. 2000
  7. ncbi Evaluation of commercial immunoassays for cross-reactivity to clenbuterol stereoisomers and bovine metabolites
    W L Shelver
    USDA, ARS, Biosciences Research Laboratory, University Station, Fargo, ND 58105 5674, USA
    Food Addit Contam 17:837-45. 2000
  8. ncbi Production and characterization of a monoclonal antibody against the beta-adrenergic agonist ractopamine
    W L Shelver
    Agricultural Research Service, U S Department of Agriculture, 5674 University Station, and Department of Veterinary and Microbiological Sciences, North Dakota State University, Fargo, North Dakota 58105, USA
    J Agric Food Chem 48:4020-6. 2000
  9. ncbi Kinetics and disposition of orally dosed sodium chlorate in sheep
    D J Smith
    USDA ARS, Biosciences Research Laboratory, Fargo, ND, USA
    J Anim Sci 90:2026-34. 2012
  10. ncbi Invited review: Efficacy, metabolism, and toxic responses to chlorate salts in food and laboratory animals
    D J Smith
    USDA ARS, Biosciences Research Laboratory, Fargo, ND 58105 2765, USA
    J Anim Sci 90:4098-117. 2012

Detail Information

Publications13

  1. ncbi Stereochemical composition of clenbuterol residues in edible tissues of swine
    D J Smith
    Biosciences Research Laboratory, Agricultural Research Service, U S Department of Agriculture, P O Box 5674, University Station, Fargo, North Dakota 58105, USA
    J Agric Food Chem 48:6036-43. 2000
    ..The effect of clenbuterol dose on its stereochemical composition in edible tissues is unknown but will be an area of further investigation...
  2. ncbi Pharmacokinetics of ruminally dosed sodium [36Cl]chlorate in beef cattle
    C E Oliver
    Department of Animal and Range Sciences, North Dakota State University, Fargo, ND, USA
    J Vet Pharmacol Ther 30:358-65. 2007
    ..Further research is needed to develop a chlorate formulation that will allow passage to the lower gastrointestinal tract...
  3. ncbi Development of an immunoassay for the beta-adrenergic agonist ractopamine
    W L Shelver
    US Department of Agriculture, Biosciences Research Laboratory, University Station, Fargo, ND 58105 5674, USA
    J Immunoassay 21:1-23. 2000
    ..The system demonstrated a matrix effect similar to other enzyme immunoassays, dilution of urine decreased but did not eliminate the matrix effect...
  4. ncbi Effect of sodium [36Cl]chlorate dose on total radioactive residues and residues of parent chlorate in growing swine
    D J Smith
    Biosciences Research Laboratory, Agricultural Research Service, U S Department of Agriculture, Fargo, North Dakota 58105 5674, USA
    J Agric Food Chem 54:8648-53. 2006
    ..No evidence for the presence of chlorite was observed in excreta or in tissues. Results of this study suggest that further development of chlorate as a preharvest food safety tool in swine merits consideration...
  5. ncbi Total radioactive residues and clenbuterol residues in swine after dietary administration of [14C]clenbuterol for seven days and preslaughter withdrawal periods of zero, three, or seven days
    D J Smith
    USDA ARS, Biosciences Research Laboratory, Fargo, ND 58105 5674, USA
    J Anim Sci 78:2903-12. 2000
    ..Results from this study indicate that clenbuterol HCl is well absorbed in swine and that the use of clenbuterol in this species in an off-label manner is inconsistent with human food safety standards used in developed countries...
  6. ncbi Response of C2C12 mouse and turkey skeletal muscle cells to the beta-adrenergic agonist ractopamine
    N W Shappell
    Biosciences Research Laboratory, ARS, USDA, Fargo, NS 58105, USA
    J Anim Sci 78:699-708. 2000
    ....
  7. ncbi Evaluation of commercial immunoassays for cross-reactivity to clenbuterol stereoisomers and bovine metabolites
    W L Shelver
    USDA, ARS, Biosciences Research Laboratory, University Station, Fargo, ND 58105 5674, USA
    Food Addit Contam 17:837-45. 2000
    ..This study illustrates the inherent problems of using unvalidated immunoassays for quantitation purposes...
  8. ncbi Production and characterization of a monoclonal antibody against the beta-adrenergic agonist ractopamine
    W L Shelver
    Agricultural Research Service, U S Department of Agriculture, 5674 University Station, and Department of Veterinary and Microbiological Sciences, North Dakota State University, Fargo, North Dakota 58105, USA
    J Agric Food Chem 48:4020-6. 2000
    ..In conclusion, a highly specific monoclonal antibody to ractopamine hydrochloride was developed that could be of potential utility in screening assays...
  9. ncbi Kinetics and disposition of orally dosed sodium chlorate in sheep
    D J Smith
    USDA ARS, Biosciences Research Laboratory, Fargo, ND, USA
    J Anim Sci 90:2026-34. 2012
    ..Rapid removal of chlorate from the gastrointestinal lumen suggests that effects of chlorate on colonic and fecal gastrointestinal bacteria may occur through mechanisms other than direct luminal contact between microbe and chlorate salts...
  10. ncbi Invited review: Efficacy, metabolism, and toxic responses to chlorate salts in food and laboratory animals
    D J Smith
    USDA ARS, Biosciences Research Laboratory, Fargo, ND 58105 2765, USA
    J Anim Sci 90:4098-117. 2012
    ..Therefore, the purpose of this review is to summarize the published data regarding the efficacy, metabolism, and toxicology of chlorate salts in target (livestock) and nontarget species...
  11. ncbi Identification of turkey biliary metabolites of ractopamine hydrochloride and the metabolism and distribution of synthetic [14C]ractopamine glucuronides in the turkey
    D J Smith
    US Department of Agriculture, Agricultural Research Service, Biosciences Research Laboratory, Fargo, ND 58105 5674, USA
    Xenobiotica 30:427-40. 2000
    ..4%. 5. Bile and urine collected from the colostomized, bile-duct cannulated bird contained mainly ractopamine glucuronides. Indirect evidence suggests that the dosed ractopamine glucuronides were not absorbed intact...
  12. ncbi Tissue residues of ractopamine and urinary excretion of ractopamine and metabolites in animals treated for 7 days with dietary ractopamine
    D J Smith
    USDA ARS, Biosciences Research Laboratory, Fargo, ND 58105 5674, USA
    J Anim Sci 80:1240-9. 2002
    ..These data indicate that after the hydrolysis of conjugates, ractopamine should be detectable in urine of sheep as long as 7 d after the last exposure to ractopamine and as long as 5 d after withdrawal in cattle...
  13. ncbi Effect of sodium [36Cl]chlorate dose on total radioactive residues and residues of parent chlorate in beef cattle
    D J Smith
    United States Department of Agriculture Agricultural Research Service, Biosciences Research Laboratory, 1605 Albrecht Boulevard, Fargo, North Dakota 58105 5674, USA
    J Agric Food Chem 53:7352-60. 2005
    ..No evidence for the presence of chlorite was observed in any tissue. Results of this study suggest that further development of chlorate as a preharvest food safety tool merits consideration...