James K Walsh

Summary

Affiliation: Sleep Medicine and Research Center
Country: USA

Publications

  1. ncbi Zolpidem "as needed" for the treatment of primary insomnia: a double-blind, placebo-controlled study
    James K Walsh
    Sleep Medicine Research Center, St Luke s Hospital, Chesterfield, Missouri 63017, USA
    Sleep Med Rev 6:S7-10; discussion S10-1, S31-3. 2002
  2. pmc Slow wave sleep enhancement with gaboxadol reduces daytime sleepiness during sleep restriction
    James K Walsh
    Sleep Medicine and Research Center, St John s Mercy Medical Center St Luke s Hospital, St Louis, MO, USA
    Sleep 31:659-72. 2008
  3. ncbi Dose-response effects of tiagabine on the sleep of older adults
    James K Walsh
    Sleep Medicine and Research Center, St John s Mercy Medical Center, St Luke s Hospital, St Louis, MO, USA
    Sleep 28:673-6. 2005
  4. ncbi Modafinil improves alertness, vigilance, and executive function during simulated night shifts
    James K Walsh
    Sleep Medicine and Research Center, affiliated with St John s Mercy Medical Center and St Luke s Hospital, St Louis, Missouri, USA
    Sleep 27:434-9. 2004
  5. ncbi Clinical and socioeconomic correlates of insomnia
    James K Walsh
    Sleep Medicine and Research Center at St Luke s Hospital, Chesterfield, MO, USA
    J Clin Psychiatry 65:13-9. 2004
  6. ncbi Tiagabine is associated with sustained attention during sleep restriction: evidence for the value of slow-wave sleep enhancement?
    James K Walsh
    Sleep Medicine and Research Center, St John s Mercy Medical Center St Luke s Hospital, St Louis, MO, USA
    Sleep 29:433-43. 2006
  7. ncbi Laboratory and field studies of naps and caffeine as practical countermeasures for sleep-wake problems associated with night work
    Paula K Schweitzer
    Sleep Medicine and Research Center affiliated with St John s Mercy Medical Center and St Luke s Hospital, St Louis, MO 2Pacific Sleep Medicine, La Jolla, CA 63017, USA
    Sleep 29:39-50. 2006
  8. doi Treatment of elderly primary insomnia patients with EVT 201 improves sleep initiation, sleep maintenance, and daytime sleepiness
    James K Walsh
    Sleep Medicine and Research Center, St Luke s Hospital, 232 S Woods Mill Road, Chesterfield, MO 63017, United States
    Sleep Med 11:23-30. 2010
  9. ncbi The selective extrasynaptic GABAA agonist, gaboxadol, improves traditional hypnotic efficacy measures and enhances slow wave activity in a model of transient insomnia
    James K Walsh
    St Johns Hospital, St Louis, MO, USA
    Sleep 30:593-602. 2007
  10. ncbi Tiagabine enhances slow wave sleep and sleep maintenance in primary insomnia
    James K Walsh
    St John s Mercy St Luke s Hospitals, Sleep Medicine and Research Center, Chesterfield, MO 63017, and Department of Psychology, St Louis University, St Louis, MO 63130, USA
    Sleep Med 7:155-61. 2006

Detail Information

Publications43

  1. ncbi Zolpidem "as needed" for the treatment of primary insomnia: a double-blind, placebo-controlled study
    James K Walsh
    Sleep Medicine Research Center, St Luke s Hospital, Chesterfield, Missouri 63017, USA
    Sleep Med Rev 6:S7-10; discussion S10-1, S31-3. 2002
  2. pmc Slow wave sleep enhancement with gaboxadol reduces daytime sleepiness during sleep restriction
    James K Walsh
    Sleep Medicine and Research Center, St John s Mercy Medical Center St Luke s Hospital, St Louis, MO, USA
    Sleep 31:659-72. 2008
    ..To evaluate the impact of enhanced slow wave sleep (SWS) on behavioral, psychological, and physiological changes resulting from sleep restriction...
  3. ncbi Dose-response effects of tiagabine on the sleep of older adults
    James K Walsh
    Sleep Medicine and Research Center, St John s Mercy Medical Center, St Luke s Hospital, St Louis, MO, USA
    Sleep 28:673-6. 2005
    ..To evaluate the dose- response effects of tiagabine on sleep and safety measures in healthy older adults...
  4. ncbi Modafinil improves alertness, vigilance, and executive function during simulated night shifts
    James K Walsh
    Sleep Medicine and Research Center, affiliated with St John s Mercy Medical Center and St Luke s Hospital, St Louis, Missouri, USA
    Sleep 27:434-9. 2004
    ..To assess the effect of 200 mg of modafinil compared to placebo on alertness, neurobehavioral performance, and executive function during 4 consecutive simulated night shifts...
  5. ncbi Clinical and socioeconomic correlates of insomnia
    James K Walsh
    Sleep Medicine and Research Center at St Luke s Hospital, Chesterfield, MO, USA
    J Clin Psychiatry 65:13-9. 2004
    ..Chronic insomnia is a common problem, often associated with negative waking mood or function. As such, heightened clinical attention and clinical research appear warranted...
  6. ncbi Tiagabine is associated with sustained attention during sleep restriction: evidence for the value of slow-wave sleep enhancement?
    James K Walsh
    Sleep Medicine and Research Center, St John s Mercy Medical Center St Luke s Hospital, St Louis, MO, USA
    Sleep 29:433-43. 2006
    ..To evaluate the impact of enhanced slow-wave sleep (SWS) on behavioral, psychological, and physiologic changes resulting from sleep restriction..
  7. ncbi Laboratory and field studies of naps and caffeine as practical countermeasures for sleep-wake problems associated with night work
    Paula K Schweitzer
    Sleep Medicine and Research Center affiliated with St John s Mercy Medical Center and St Luke s Hospital, St Louis, MO 2Pacific Sleep Medicine, La Jolla, CA 63017, USA
    Sleep 29:39-50. 2006
    ..To evaluate the effects of napping, caffeine, and napping plus caffeine on performance and alertness in both laboratory and field settings...
  8. doi Treatment of elderly primary insomnia patients with EVT 201 improves sleep initiation, sleep maintenance, and daytime sleepiness
    James K Walsh
    Sleep Medicine and Research Center, St Luke s Hospital, 232 S Woods Mill Road, Chesterfield, MO 63017, United States
    Sleep Med 11:23-30. 2010
    ..Two doses of EVT 201, a partial positive allosteric modulator of the GABA(A) system, were evaluated in elderly primary insomnia patients with daytime sleepiness...
  9. ncbi The selective extrasynaptic GABAA agonist, gaboxadol, improves traditional hypnotic efficacy measures and enhances slow wave activity in a model of transient insomnia
    James K Walsh
    St Johns Hospital, St Louis, MO, USA
    Sleep 30:593-602. 2007
    ..Evaluate the hypnotic efficacy of gaboxadol, a selective extrasynaptic GABAA agonist (SEGA), in a phase advance model of transient insomnia...
  10. ncbi Tiagabine enhances slow wave sleep and sleep maintenance in primary insomnia
    James K Walsh
    St John s Mercy St Luke s Hospitals, Sleep Medicine and Research Center, Chesterfield, MO 63017, and Department of Psychology, St Louis University, St Louis, MO 63130, USA
    Sleep Med 7:155-61. 2006
    ..To evaluate the effect of tiagabine on sleep and next-morning alertness and performance in adult patients with primary insomnia...
  11. ncbi Tiagabine increases slow-wave sleep in a dose-dependent fashion without affecting traditional efficacy measures in adults with primary insomnia
    James K Walsh
    Sleep Medicine and Research Center, St Johnś St Lukeś Hospitals, St Louis, MO 63017, USA
    J Clin Sleep Med 2:35-41. 2006
    ..This study evaluated dose-response effects of tiagabine on sleep in adults with primary insomnia...
  12. doi A convenient expiratory positive airway pressure nasal device for the treatment of sleep apnea in patients non-adherent with continuous positive airway pressure
    James K Walsh
    Sleep Medicine and Research Center, St Luke s Hospital, 232 S Woods Mill Rd, Chesterfield, MO, USA
    Sleep Med 12:147-52. 2011
    ..The short-term efficacy of and adherence with a convenient expiratory positive airway pressure (EPAP) nasal device was evaluated in OSA patients non-adherent with CPAP...
  13. pmc Nightly treatment of primary insomnia with eszopiclone for six months: effect on sleep, quality of life, and work limitations
    James K Walsh
    Sleep Medicine and Research Center, St John s St Luke s Hospitals and the Department of Psychology, Saint Louis University, St Louis, MO 63017, USA
    Sleep 30:959-68. 2007
    ..To evaluate 6 months' eszopiclone treatment upon patient-reported sleep, fatigue and sleepiness, insomnia severity, quality of life, and work limitations...
  14. doi Efficacy and safety of zolpidem extended release in elderly primary insomnia patients
    James K Walsh
    Sleep Medicine and Research Center, St John s Mercy and St Luke s Hospitals, 232 S Woods Hill Road, Chesterfield, MO 63017, USA
    Am J Geriatr Psychiatry 16:44-57. 2008
    ..To evaluate the clinical efficacy and safety of zolpidem extended release for the treatment of primary insomnia in elderly patients...
  15. pmc Enhancing slow wave sleep with sodium oxybate reduces the behavioral and physiological impact of sleep loss
    James K Walsh
    Sleep Medicine and Research Center, St Luke s Hospital, Chesterfield, MO 63017, USA
    Sleep 33:1217-25. 2010
    ..To investigate whether enhancement of slow wave sleep (SWS) with sodium oxybate reduces the impact of sleep deprivation...
  16. ncbi Efficacy of the selective extrasynaptic GABA A agonist, gaboxadol, in a model of transient insomnia: a randomized, controlled clinical trial
    James K Walsh
    St John s Hospital, St Louis, MO, USA
    Sleep Med 9:393-402. 2008
    ..The hypnotic efficacy of gaboxadol, a selective extrasynaptic GABA A agonist (SEGA), was evaluated in a phase-advance model of transient insomnia...
  17. ncbi The partial positive allosteric GABA(A) receptor modulator EVT 201 is efficacious and safe in the treatment of adult primary insomnia patients
    James K Walsh
    Sleep Medicine and Research Center, St Luke s Hospital, 232 S Woods Mill Road, Chesterfield, MO 63017, USA
    Sleep Med 10:859-64. 2009
    ..To evaluate polysomnographic (PSG) and self-reported measures of the efficacy and safety of EVT 201 in patients with primary insomnia...
  18. ncbi Efficacy and tolerability of indiplon in older adults with primary insomnia
    James K Walsh
    Sleep Medicine and Research Center, St John s St Luke s Hospitals, 232 S Woods Mill Road, Chesterfield, St Louis, MO 63017, USA
    Sleep Med 8:753-9. 2007
    ..To evaluate the efficacy and safety of indiplon in elderly patients with primary insomnia...
  19. pmc Nighttime insomnia symptoms and perceived health in the America Insomnia Survey (AIS)
    James K Walsh
    Sleep Medicine and Research Center, St Luke s Hospital, St Louis, MO, USA
    Sleep 34:997-1011. 2011
    ....
  20. pmc The effect of two benzodiazepine receptor agonist hypnotics on sleep-dependent memory consolidation
    Janine M Hall-Porter
    Sleep Medicine and Research Center, St Luke s Hospital, Chesterfield, MO
    J Clin Sleep Med 10:27-34. 2014
    ....
  21. ncbi Understanding GABA and its relation to insomnia and therapeutics
    James K Walsh
    Sleep Medicine and Research Center, St John K St Luke s Hospitals, Department of Psychology, Saint Louis University, St Louis, MO, USA
    J Clin Sleep Med 2:S5-6. 2006
  22. ncbi Pharmacologic management of insomnia: past, present, and future
    Denise Troy Curry
    Sleep Medicine and Research Center, St John s Mercy Medical Center and St Luke s Hospital, Chesterfield, MO 63017, USA
    Psychiatr Clin North Am 29:871-93; abstract vii-viii. 2006
    ..Improvement in managing insomnia will result from systematic research with these drugs, with drugs in development, and with novel uses, such as co-therapy...
  23. ncbi Pharmacologic management of insomnia
    James K Walsh
    Sleep Medicine and Research Center, St John s Mercy and St Luke s Hospitals, Department of Psychiatry, Saint Louis University, St Louis, MO, USA
    J Clin Psychiatry 65:41-5. 2004
    ..Sedating antidepressants are also frequently prescribed to promote sleep despite inadequate data to support their efficacy for this indication and a greater potential for clinically troublesome side effects...
  24. doi Strategies for de-identification and anonymization of electronic health record data for use in multicenter research studies
    Clete A Kushida
    Stanford Sleep Medicine Center, Redwood City, CA 94063 5704, USA
    Med Care 50:S82-101. 2012
    ..The use of these strategies in multicenter research studies is paramount in importance, given the need to share electronic health record data across multiple environments and institutions while safeguarding patient privacy...
  25. ncbi Drugs used to treat insomnia in 2002: regulatory-based rather than evidence-based medicine
    James K Walsh
    Sleep 27:1441-2. 2004
  26. pmc A polysomnographic placebo-controlled evaluation of the efficacy and safety of eszopiclone relative to placebo and zolpidem in the treatment of primary insomnia
    Milton K Erman
    Pacific Sleep Medicine Services, Inc, San Diego, CA, USA
    J Clin Sleep Med 4:229-34. 2008
    ..To evaluate the polysomnographic efficacy and the safety of a range of doses of eszopiclone relative to placebo in patients with primary insomnia. Zolpidem 10 mg was included as an active control...
  27. ncbi Efficacy and safety of zolpidem-MR: a double-blind, placebo-controlled study in adults with primary insomnia
    Thomas Roth
    Henri Ford Hospital, Detroit, MI 48202, USA
    Sleep Med 7:397-406. 2006
    ..To evaluate the clinical efficacy and safety of modified-release zolpidem (zolpidem-MR 12.5mg) for the treatment of primary insomnia in adults...
  28. ncbi Shift work sleep disorder: prevalence and consequences beyond that of symptomatic day workers
    Christopher L Drake
    Henry Ford Hospital Sleep Disorders and Research Center, Detroit, MI 48202, USA
    Sleep 27:1453-62. 2004
    ..The present study was designed to determine the relative prevalence and negative consequences associated with shift work sleep disorder in a representative sample drawn from the working population of metropolitan Detroit...
  29. ncbi Long-term, non-nightly administration of zolpidem in the treatment of patients with primary insomnia
    Michael L Perlis
    Sleep and Neurophysiology Laboratory, Department of Psychiatry, University of Rochester, and the University of Rochester Medical Center, Neurosciences Program, Rochester, NY 14642, USA
    J Clin Psychiatry 65:1128-37. 2004
    ..The present study was designed to further evaluate this issue within a large scale, double-blind, placebo-controlled, long-term trial...
  30. ncbi Sustained efficacy of eszopiclone over 6 months of nightly treatment: results of a randomized, double-blind, placebo-controlled study in adults with chronic insomnia
    Andrew D Krystal
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
    Sleep 26:793-9. 2003
    ..To determine the long-term efficacy of eszopiclone in patients with chronic insomnia...
  31. ncbi Modafinil for excessive sleepiness associated with shift-work sleep disorder
    Charles A Czeisler
    Division of Sleep Medicine, Harvard Medical School, and Brigham and Women s Hospital, Boston, MA 02115, USA
    N Engl J Med 353:476-86. 2005
    ..Patients with shift-work sleep disorder chronically have excessive sleepiness during night work and insomnia when attempting to sleep during the day. We evaluated the use of modafinil for treating sleepiness in patients with this disorder...
  32. ncbi Ramelteon (TAK-375), a selective MT1/MT2-receptor agonist, reduces latency to persistent sleep in a model of transient insomnia related to a novel sleep environment
    Thomas Roth
    Sleep Disorders and Research Center, Henry Ford Hospital, Detroit, MI 48202, USA
    Sleep 28:303-7. 2005
    ..Evaluate the efficacy of ramelteon, an MT/1MT2-receptor agonist, for the treatment of transient insomnia in healthy adults...
  33. ncbi An evaluation of the efficacy and safety of eszopiclone over 12 months in patients with chronic primary insomnia
    Thomas Roth
    Henry Ford Hospital Sleep Center, 2799 West Grand Blvd, CFP 3, Detroit, MI 48202, USA
    Sleep Med 6:487-95. 2005
    ..A double-blind placebo-controlled study of eszopiclone found significant, sustained improvement in sleep and daytime function. The 6-month open-label extension phase is described herein...
  34. ncbi Frequent napping is associated with excessive daytime sleepiness, depression, pain, and nocturia in older adults: findings from the National Sleep Foundation '2003 Sleep in America' Poll
    Daniel J Foley
    Center for Mental Health Services DJF, Substance Abuse and Mental Health Services Administration, Department of Health and Human Services, Rockville, MD 20857, USA
    Am J Geriatr Psychiatry 15:344-50. 2007
    ..The objective of this study was to describe the prevalence and correlates of regular napping among older adults...
  35. ncbi The direct and indirect costs of untreated insomnia in adults in the United States
    Ronald J Ozminkowski
    Institute for Health and Productivity Studies, Cornell University, Washington, D C, USA
    Sleep 30:263-73. 2007
    ..To estimate the direct and indirect cost burden of untreated insomnia among younger adults (age 18-64), and to estimate the direct costs of untreated insomnia for elderly patients (age 65 and over)...
  36. ncbi The efficacy and safety of armodafinil as treatment for adults with excessive sleepiness associated with narcolepsy
    John R Harsh
    The University of Southern Mississippi, Hattiesburg, MS 39406, USA
    Curr Med Res Opin 22:761-74. 2006
    ..This study assessed the efficacy and safety of armodafinil, the longer half-life enantiomer of modafinil, for the treatment of excessive sleepiness in patients with narcolepsy...
  37. ncbi Insights into the public health burden of insomnia
    James K Walsh
    Sleep 29:142-3. 2006
  38. ncbi The Apnea Positive Pressure Long-term Efficacy Study (APPLES): rationale, design, methods, and procedures
    Clete A Kushida
    Stanford Universit y, Stanfbrd, CA, USA
    J Clin Sleep Med 2:288-300. 2006
    ..To assess the size, time course, and durability of the effects of long-term continuous positive airway pressure (CPAP) therapy on neurocognitive function, mood, sleepiness, and quality of life in patients with obstructive sleep apnea...
  39. ncbi Efficacy and tolerability of modified-release indiplon in elderly patients with chronic insomnia: results of a 2-week double-blind, placebo-controlled trial
    R Bruce Lydiard
    Department of Neuropsychiatny and Behavioral Science University of South Carolina, Columbia, SC, USA
    J Clin Sleep Med 2:309-15. 2006
    ..The aim of the present study was to evaluate the efficacy and safety of a 15-mg nightly dose of modified-release indiplon tablets in elderly patients with primary insomnia characterized by sleep-maintenance difficulties...
  40. ncbi The treatment of chronic insomnia: drug indications, chronic use and abuse liability. Summary of a 2001 New Clinical Drug Evaluation Unit meeting symposium
    Wallace B Mendelson
    Sleep Med Rev 8:7-17. 2004
    ..All currently available agents, while effective and safe, do not achieve this ideal. The next few years are likely to see the appearance of a variety of agents with new and promising mechanisms of action...
  41. pmc History of the development of sleep medicine in the United States
    John W Shepard
    Sleep Disorders Center, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    J Clin Sleep Med 1:61-82. 2005
    ....
  42. ncbi Panel discussion: changing how we think about insomnia
    Sonia Ancoli-Israel
    J Clin Psychiatry 65:44-6. 2004
  43. ncbi Tiredness versus sleepiness: semantics or a target for public education?
    William C Dement
    Sleep Research Center and Department of Psychiatry, Stanford University, Palo Alto, CA, USA
    Sleep 26:485-6. 2003