Sulie L Chang

Summary

Affiliation: Seton Hall University
Country: USA

Publications

  1. doi request reprint Behavioral and molecular evidence for a feedback interaction between morphine and HIV-1 viral proteins
    Sulie L Chang
    Institute of Neuroimmune Pharmacology, Seton Hall University, 400 South Orange Avenue, South Orange, NJ 07079, USA
    J Neuroimmune Pharmacol 7:332-40. 2012
  2. doi request reprint Neuroimmune pharmacology: an elective course for molecular and cellular bioscience graduate programs
    Sulie L Chang
    Institute of Neuroimmune Pharmacology, Seton Hall University, South Orange, NJ 07079, USA
    J Neuroimmune Pharmacol 6:71-5. 2011
  3. pmc Interleukin-1 beta-induced up-regulation of opioid receptors in the untreated and morphine-desensitized U87 MG human astrocytoma cells
    Linda Staikos Byrne
    Institute of Neuroimmune Pharmacology, Seton Hall University, 400 South Orange Ave, South Orange, NJ 07079, USA
    J Neuroinflammation 9:252. 2012
  4. pmc Expression of the mu opioid receptor in the human immunodeficiency virus type 1 transgenic rat model
    Sulie L Chang
    Department of Biological Sciences, Seton Hall University, 400 South Orange Avenue, South Orange, NJ 07079, USA
    J Virol 81:8406-11. 2007
  5. doi request reprint Lipopolysaccharide-induced pro-inflammatory cytokines in the brain of rats in the morphine-tolerant state
    Linda Staikos
    Institute of Neuroimmune Pharmacology, Seton Hall University, 400 South Orange Ave, South Orange, NJ 07079, USA
    J Neuroimmune Pharmacol 3:236-40. 2008
  6. pmc A role for reactive oxygen species in endotoxin-induced elevation of MOR expression in the nervous and immune systems
    Erik F Langsdorf
    Institute of Neuroimmune Pharmacology, Seton Hall University, 400 South Orange Ave, South Orange, NJ 07079, USA
    J Neuroimmunol 236:57-64. 2011
  7. ncbi request reprint Chronic morphine accelerates the progression of lipopolysaccharide-induced sepsis to septic shock
    Frank M Ocasio
    Department of Biology, Seton Hall University, 400 South Orange Avenue, South Orange, NJ 07079, USA
    J Neuroimmunol 149:90-100. 2004
  8. pmc Age- and ethanol concentration-dependent effects of acute binge drinking in the HIV-1 transgenic rat
    Sraboni Sarkar
    Institute of Neuroimmune Pharmacology, Seton Hall University, South Orange, New Jersey 07079, USA
    Alcohol Clin Exp Res 37:E70-8. 2013
  9. ncbi request reprint Expression and regulation of the mu opioid peptide receptor in TPA-differentiated HL-60 promyelocytic leukemia cells
    Jose A Beltran
    Department of Biology, Seton Hall University, McNulty Hall, Room 215, South Orange, NJ 07079, USA
    Int Immunopharmacol 6:1331-40. 2006
  10. ncbi request reprint The effects of repeated endotoxin exposure on rat brain metabolites as measured by ex vivo 1HMRS
    Sulie L Chang
    Department of Biology, Seton Hall University, 400 South Orange Avenue, South Orange, NJ 07079, USA
    J Neuroimmunol 166:39-46. 2005

Research Grants

  1. MORPHINE ACTIONS ON THE IMMUNE SYSTEM
    SULIE CHANG; Fiscal Year: 2006
  2. MORPHINE ACTIONS ON THE IMMUNE SYSTEM
    SULIE CHANG; Fiscal Year: 2009
  3. Mechanisms of Nicotine's Behavioral Effects on the HIV-1 Transgenic Rat
    SULIE CHANG; Fiscal Year: 2009
  4. MORPHINE ACTIONS ON THE IMMUNE SYSTEM
    SULIE LIN CHANG; Fiscal Year: 2010
  5. Mechanisms of Nicotine's Behavioral Effects on the HIV-1 Transgenic Rat
    Ming D Li; Fiscal Year: 2010
  6. MORPHINE ACTIONS ON THE IMMUNE SYSTEM
    SULIE CHANG; Fiscal Year: 2009
  7. MORPHINE ACTIONS ON THE IMMUNE SYSTEM
    SULIE CHANG; Fiscal Year: 2001
  8. MORPHINE ACTIONS ON THE IMMUNE SYSTEM
    SULIE LIN CHANG; Fiscal Year: 2010

Collaborators

  • Xin Mao
  • L Chang
  • Ming D Li
  • Junran Cao
  • Chuang Liu
  • Christine C Cloak
  • He Li
  • Michael Vigorito
  • Sraboni Sarkar
  • Erik F Langsdorf
  • Jinsong Peng
  • Jose A Beltran
  • Xiangqian Liu
  • Abigail L LaShomb
  • Linda Staikos Byrne
  • Natasha F Homji
  • Marley D Kass
  • Linda Staikos
  • Lorenc Malellari
  • Karolina M Kolodziejska-Akiyama
  • Ru Chen
  • Yuhui Jiang
  • Hsien Ching Liu
  • Steven D House
  • Frank M Ocasio
  • Xin Yu
  • Marley Kass
  • Anitha Pallur
  • Jennifer Peek
  • Heping Zhou
  • Jose Beltran
  • Young May Cha
  • Horace H Loh
  • Jenine K Anday
  • Allan D Blake
  • Wen Xin Li

Detail Information

Publications25

  1. doi request reprint Behavioral and molecular evidence for a feedback interaction between morphine and HIV-1 viral proteins
    Sulie L Chang
    Institute of Neuroimmune Pharmacology, Seton Hall University, 400 South Orange Avenue, South Orange, NJ 07079, USA
    J Neuroimmune Pharmacol 7:332-40. 2012
    ..Some of the mechanisms underlying the feedback interaction between morphine and HIV-1 viral proteins has been demonstrated using cell culture and the recently engineered HIV-1 transgenic (HIV-1Tg) rat models...
  2. doi request reprint Neuroimmune pharmacology: an elective course for molecular and cellular bioscience graduate programs
    Sulie L Chang
    Institute of Neuroimmune Pharmacology, Seton Hall University, South Orange, NJ 07079, USA
    J Neuroimmune Pharmacol 6:71-5. 2011
    ..The goal of this elective course is to help prepare future molecular and cellular biologists to undertake research initiatives in the field of neuroimmunity in health and disease...
  3. pmc Interleukin-1 beta-induced up-regulation of opioid receptors in the untreated and morphine-desensitized U87 MG human astrocytoma cells
    Linda Staikos Byrne
    Institute of Neuroimmune Pharmacology, Seton Hall University, 400 South Orange Ave, South Orange, NJ 07079, USA
    J Neuroinflammation 9:252. 2012
    ..We hypothesized that IL-1β up-regulates opioid receptors in human astrocytes in both untreated and morphine-desensitized states...
  4. pmc Expression of the mu opioid receptor in the human immunodeficiency virus type 1 transgenic rat model
    Sulie L Chang
    Department of Biological Sciences, Seton Hall University, 400 South Orange Avenue, South Orange, NJ 07079, USA
    J Virol 81:8406-11. 2007
    ..Furthermore, our results demonstrate that the new HIV-1Tg rat model can be a valuable tool with which to study MOR gene expression and its effects in the continuous presence of HIV viral proteins...
  5. doi request reprint Lipopolysaccharide-induced pro-inflammatory cytokines in the brain of rats in the morphine-tolerant state
    Linda Staikos
    Institute of Neuroimmune Pharmacology, Seton Hall University, 400 South Orange Ave, South Orange, NJ 07079, USA
    J Neuroimmune Pharmacol 3:236-40. 2008
    ..IL-1beta mRNA increased 2 h post-LPS treatment, whereas IL-6 decreased. At 16 h, TNF-alpha expression mRNA increased. These data suggest that the inflammatory response in the brain is heightened during morphine tolerance...
  6. pmc A role for reactive oxygen species in endotoxin-induced elevation of MOR expression in the nervous and immune systems
    Erik F Langsdorf
    Institute of Neuroimmune Pharmacology, Seton Hall University, 400 South Orange Ave, South Orange, NJ 07079, USA
    J Neuroimmunol 236:57-64. 2011
    ..These data suggest that the endotoxin, LPS, modulates MOR expression in nervous and immune cells via ROS signaling, and demonstrates the crosstalk that exists within the neuroimmune axis...
  7. ncbi request reprint Chronic morphine accelerates the progression of lipopolysaccharide-induced sepsis to septic shock
    Frank M Ocasio
    Department of Biology, Seton Hall University, 400 South Orange Avenue, South Orange, NJ 07079, USA
    J Neuroimmunol 149:90-100. 2004
    ..Our study presents both the molecular and cellular mechanisms underlying the potentiated LPS-induced inflammation and accelerated progression to septic shock seen with chronic morphine exposure...
  8. pmc Age- and ethanol concentration-dependent effects of acute binge drinking in the HIV-1 transgenic rat
    Sraboni Sarkar
    Institute of Neuroimmune Pharmacology, Seton Hall University, South Orange, New Jersey 07079, USA
    Alcohol Clin Exp Res 37:E70-8. 2013
    ..We found age-dependent expression of HIV-1 viral proteins in the HIV-1 transgenic (HIV-1Tg) rat. Thus, we hypothesized that there are age- and EtOH concentration-dependent effects of binge drinking in HIV-1-positive individuals...
  9. ncbi request reprint Expression and regulation of the mu opioid peptide receptor in TPA-differentiated HL-60 promyelocytic leukemia cells
    Jose A Beltran
    Department of Biology, Seton Hall University, McNulty Hall, Room 215, South Orange, NJ 07079, USA
    Int Immunopharmacol 6:1331-40. 2006
    ....
  10. ncbi request reprint The effects of repeated endotoxin exposure on rat brain metabolites as measured by ex vivo 1HMRS
    Sulie L Chang
    Department of Biology, Seton Hall University, 400 South Orange Avenue, South Orange, NJ 07079, USA
    J Neuroimmunol 166:39-46. 2005
    ..These findings suggest that chronic inflammation induced by LPS could lead to cell loss/dysfunction, and hence, desensitization of the HPA axis, particularly in the hypothalamus...
  11. doi request reprint Further characterization of the spatial learning deficit in the human immunodeficiency virus-1 transgenic rat
    Abigail L LaShomb
    Department of Psychology, Seton Hall University, South Orange, NJ 07079, USA
    J Neurovirol 15:14-24. 2009
    ..These results indicate that the HIV-1Tg rat is a promising model in which to study the neuropathogenic mechanisms that can cause cognitive deficits in patients with HAD as well as asymptomatic HIV-positive individuals...
  12. doi request reprint Methamphetamine-induced behavioral and physiological effects in adolescent and adult HIV-1 transgenic rats
    Marley D Kass
    Institute of Neuroimmune Pharmacology, Seton Hall University, South Orange, NJ 07079, USA
    J Neuroimmune Pharmacol 5:566-73. 2010
    ..Thus, HIV-infected individuals and adolescents may be more vulnerable to the development of METH abuse and dependence than non-infected individuals and adults...
  13. doi request reprint Methamphetamine-induced behavioral sensitization is enhanced in the HIV-1 transgenic rat
    Xiangqian Liu
    Institute of Neuroimmune Pharmacology, Seton Hall University, South Orange, NJ 07079, USA
    J Neuroimmune Pharmacol 4:309-16. 2009
    ..Our results indicate that METH-induced behavioral sensitization is greater in the presence of HIV infection and suggest that D1R expression in the prefrontal cortex may play a role in METH addiction in HIV-positive individuals...
  14. pmc Endotoxin-induced cytokine and chemokine expression in the HIV-1 transgenic rat
    Natasha F Homji
    Institute of Neuroimmune Pharmacology, Seton Hall University, South Orange, NJ 07079, USA
    J Neuroinflammation 9:3. 2012
    ..HIV-1 viral proteins are known to have an adverse effect on the immune system. However, the effects of HIV-1 viral proteins during ET have not been investigated...
  15. doi request reprint Methamphetamine-mediated modulation of MOR expression in the SH-SY5Y neuroblastoma cell line
    Erik F Langsdorf
    Institute of NeuroImmune Pharmacology and Department of Biological Sciences, Seton, Hall University, South Orange, New Jersey 07079, USA
    Synapse 65:858-65. 2011
    ..Taken together, our data show that METH's effect on MOR expression is dependent upon sublethal levels of intracellular ROS, which suggests a possible coupling of METH- and opiate-mediated intracellular signaling...
  16. pmc Acquisition and long-term retention of spatial learning in the human immunodeficiency virus-1 transgenic rat: effects of repeated nicotine treatment
    Michael Vigorito
    Institute of Neuroimmune Pharmacology, Seton Hall University, 400 South Orange Avenue, South Orange, NJ 07079, USA
    J Neurovirol 19:157-65. 2013
    ..The results, however, do not provide any evidence of the amelioration of the learning deficit observed in this behavioral model at least with the nicotine dose tested...
  17. pmc Ethanol concentration-dependent alterations in gene expression during acute binge drinking in the HIV-1 transgenic rat
    Sraboni Sarkar
    Institute of Neuroimmune Pharmacology, Seton Hall University, South Orange, NJ 07079, USA
    Alcohol Clin Exp Res 37:1082-90. 2013
    ....
  18. ncbi request reprint HIV-1 gp120 up-regulation of the mu opioid receptor in TPA-differentiated HL-60 cells
    Jose A Beltran
    Department of Biology, Seton Hall University, McNulty Hall, Room 215, South Orange, NJ 07079, USA
    Int Immunopharmacol 6:1459-67. 2006
    ..Our data suggest that one of the mechanisms by which HIV-1 gp120 up-regulates the MOR in TPA-differentiated HL-60 cells is through autocrine/paracrine actions of TNF-alpha via the TNFR-II receptor...
  19. doi request reprint Involvement of the NLRP3 inflammasome in the modulation of an LPS-induced inflammatory response during morphine tolerance
    Xin Mao
    Institute of Neuroimmune Pharmacology, Seton Hall University, 400 South Orange Avenue, South Orange, NJ 07079, USA
    Drug Alcohol Depend 132:38-46. 2013
    ..We have explored the effects of lipopolysaccharide (LPS) during morphine tolerance on expression of the NLRP3 inflammasome and related inflammatory genes...
  20. pmc Opioid receptor expression in human brain and peripheral tissues using absolute quantitative real-time RT-PCR
    Jinsong Peng
    Institute of Neuroimmune Pharmacology, Seton Hall University, 400 South Orange Avenue, South Orange, NJ 07079, USA
    Drug Alcohol Depend 124:223-8. 2012
    ..The actions of endogenous opioid peptides are mediated by 3 main classes of opioid receptors; mu (MOR), kappa (KOR), and delta (DOR)...
  21. ncbi request reprint Spatial learning and memory in HIV-1 transgenic rats
    Michael Vigorito
    Department of Psychology, Seton Hall University, South Orange, NJ 07079, USA
    J Neuroimmune Pharmacol 2:319-28. 2007
    ..These results suggest that the noninfectious HIV-1Tg rat can be a valid model for the behavioral studies of HIV-related neurological dysfunction...
  22. ncbi request reprint Morphine and endomorphins differentially regulate micro-opioid receptor mRNA in SHSY-5Y human neuroblastoma cells
    Xin Yu
    Department of Biology, Seton Hall University, 400 South Orange Ave, South Orange, NJ 07079, USA
    J Pharmacol Exp Ther 306:447-54. 2003
    ..Together, our studies indicate that the opioid alkaloid morphine and the opioid peptides endomorphin-1 and -2 differentially regulate MOR mRNA expression and MOR function in SHSY-5Y cells...
  23. ncbi request reprint Differential expression of cytokines in the brain and serum during endotoxin tolerance
    Ru Chen
    Department of Biology, Seton Hall University, 400 South Orange Avenue, South Orange, NJ 07079, USA
    J Neuroimmunol 163:53-72. 2005
    ....
  24. ncbi request reprint Dual effects of morphine on permeability and apoptosis of vascular endothelial cells: morphine potentiates lipopolysaccharide-induced permeability and apoptosis of vascular endothelial cells
    Hsien Ching Liu
    Department of Biology, Seton Hall University, 400 South Orange, NJ 07079, USA
    J Neuroimmunol 146:13-21. 2004
    ..Furthermore, RT-PCR analysis revealed that morphine and LPS up-regulated Fas expression. These data suggest potential crosstalk between the signaling pathways that mediate morphine- and LPS-triggered apoptosis in brain VEC...
  25. ncbi request reprint Ethanol-induced FOS immunoreactivity in the brain of mu-opioid receptor knockout mice
    Karolina M Kolodziejska-Akiyama
    Department of Biology, Seton Hall University, 400 South Orange Avenue, South Orange, NJ 07079, USA
    Drug Alcohol Depend 80:161-8. 2005
    ..However, the mu-opioid receptor may be significant in mediating ethanol's effects in some restricted areas of the brain...

Research Grants26

  1. MORPHINE ACTIONS ON THE IMMUNE SYSTEM
    SULIE CHANG; Fiscal Year: 2006
    ....
  2. MORPHINE ACTIONS ON THE IMMUNE SYSTEM
    SULIE CHANG; Fiscal Year: 2009
    ..Therefore, the data from the proposed studies can have substantial clinical significance in the understanding and treatment of HIV infection and AIDS. ..
  3. Mechanisms of Nicotine's Behavioral Effects on the HIV-1 Transgenic Rat
    SULIE CHANG; Fiscal Year: 2009
    ....
  4. MORPHINE ACTIONS ON THE IMMUNE SYSTEM
    SULIE LIN CHANG; Fiscal Year: 2010
    ..Therefore, the data from the proposed studies can have substantial clinical significance in the understanding and treatment of HIV infection and AIDS. ..
  5. Mechanisms of Nicotine's Behavioral Effects on the HIV-1 Transgenic Rat
    Ming D Li; Fiscal Year: 2010
    ....
  6. MORPHINE ACTIONS ON THE IMMUNE SYSTEM
    SULIE CHANG; Fiscal Year: 2009
    ..Therefore, the data from the proposed studies can have substantial clinical significance in the understanding and treatment of HIV infection and AIDS. ..
  7. MORPHINE ACTIONS ON THE IMMUNE SYSTEM
    SULIE CHANG; Fiscal Year: 2001
    ..Specifically, these will establish the mechanisms by which morphine exposure affects IL-1-mediated pathways at the molecular, cellular and system levels. ..
  8. MORPHINE ACTIONS ON THE IMMUNE SYSTEM
    SULIE LIN CHANG; Fiscal Year: 2010
    ..Therefore, the data from the proposed studies can have substantial clinical significance in the understanding and treatment of HIV infection and AIDS. ..