R P Huang

Summary

Affiliation: Seattle Rheumatology Associates
Country: USA

Publications

  1. ncbi request reprint Suppression of human fibrosarcoma cell growth by transcription factor, Egr-1, involves down-regulation of Bcl-2
    R P Huang
    Molecular Medicine, Northwest Hospital, Seattle, WA 98125, USA
    Int J Cancer 77:880-6. 1998
  2. ncbi request reprint Reversion of the neoplastic phenotype of human glioblastoma cells by connexin 43 (cx43)
    R P Huang
    Northwest Hospital, Seattle, Washington 98125, USA or
    Cancer Res 58:5089-96. 1998
  3. ncbi request reprint Reduced connexin43 expression in high-grade human brain glioma cells
    R P Huang
    Molecular Medicine, Northwest Hospital, Seattle, Washington 98125, USA
    J Surg Oncol 70:21-4. 1999
  4. ncbi request reprint Tumor promotion by hydrogen peroxide in rat liver epithelial cells
    R P Huang
    Molecular Medicine, Northwest Hospital, Seattle, WA 98125, USA
    Carcinogenesis 20:485-92. 1999
  5. ncbi request reprint UV irradiation upregulates Egr-1 expression at transcription level
    R P Huang
    Molecular Medicine, Northwest Hospital, Seattle, Washington 98125, USA
    J Cell Biochem 73:227-36. 1999
  6. ncbi request reprint Impaired expression and posttranslational processing of connexin43 and downregulation of gap junctional communication in neoplastic human prostate cells
    M Z Hossain
    Department of Molecular Medicine, Northwest Hospital, Seattle, Washington 98125, USA
    Prostate 38:55-9. 1999
  7. ncbi request reprint Decreased Egr-1 expression in human, mouse and rat mammary cells and tissues correlates with tumor formation
    R P Huang
    Department of Molecular Medicine, Northwest Hospital, Seattle, WA 98125, USA
    Int J Cancer 72:102-9. 1997

Detail Information

Publications7

  1. ncbi request reprint Suppression of human fibrosarcoma cell growth by transcription factor, Egr-1, involves down-regulation of Bcl-2
    R P Huang
    Molecular Medicine, Northwest Hospital, Seattle, WA 98125, USA
    Int J Cancer 77:880-6. 1998
    ..Our results suggest that suppression of tumor cell proliferation by Egr-1 may be at least partially mediated through the down-regulation of Bcl-2...
  2. ncbi request reprint Reversion of the neoplastic phenotype of human glioblastoma cells by connexin 43 (cx43)
    R P Huang
    Northwest Hospital, Seattle, Washington 98125, USA or
    Cancer Res 58:5089-96. 1998
    ..We conclude that the loss of cx43 expression may play a role in the development of human gliomas and that cx43 acts as a tumor suppressor gene to human glioblastoma...
  3. ncbi request reprint Reduced connexin43 expression in high-grade human brain glioma cells
    R P Huang
    Molecular Medicine, Northwest Hospital, Seattle, Washington 98125, USA
    J Surg Oncol 70:21-4. 1999
    ..To further investigate the role of cx43 in the development of human gliomas, we performed the present study on human glioma grades I-IV...
  4. ncbi request reprint Tumor promotion by hydrogen peroxide in rat liver epithelial cells
    R P Huang
    Molecular Medicine, Northwest Hospital, Seattle, WA 98125, USA
    Carcinogenesis 20:485-92. 1999
    ..These results suggest that H2O2 acts as a tumor promoter in rat liver non-neoplastic epithelial cells and that the induction of IE genes and disruption of GJC are two possible targets of H2O2 during the tumor promotion process...
  5. ncbi request reprint UV irradiation upregulates Egr-1 expression at transcription level
    R P Huang
    Molecular Medicine, Northwest Hospital, Seattle, Washington 98125, USA
    J Cell Biochem 73:227-36. 1999
    ..UVA and UVB also strongly induced Egr-1 expression. These results indicate that UVC regulates Egr-1 expression at transcription level. The induction pattern of Egr-1 by UV suggests the importance of Egr-1 in the UV response...
  6. ncbi request reprint Impaired expression and posttranslational processing of connexin43 and downregulation of gap junctional communication in neoplastic human prostate cells
    M Z Hossain
    Department of Molecular Medicine, Northwest Hospital, Seattle, Washington 98125, USA
    Prostate 38:55-9. 1999
    ..Lack of adequate information on the status of gap junctions during prostate neoplasia prompted us to examine this form of cancer, which comprises about 14% of male cancer deaths in America...
  7. ncbi request reprint Decreased Egr-1 expression in human, mouse and rat mammary cells and tissues correlates with tumor formation
    R P Huang
    Department of Molecular Medicine, Northwest Hospital, Seattle, WA 98125, USA
    Int J Cancer 72:102-9. 1997
    ..We concluded, therefore, that loss of Egr-1 expression may play a role in the deregulation of normal growth in the tumorigenic process and that Egr-1 acts as a tumor suppressor gene...