B V Manyam

Summary

Affiliation: Scott and White Memorial Hospital
Country: USA

Publications

  1. ncbi Malignant melanoma and levodopa in Parkinson's disease: causality or coincidence?
    Katherine H Fiala
    Department of Neurology, Texas A and M University System, Health Science Center College of Medicine, 2401 South 31st Street, Temple, TX 76508, USA
    Parkinsonism Relat Disord 9:321-7. 2003
  2. ncbi Neuroprotective effects of the antiparkinson drug Mucuna pruriens
    Bala V Manyam
    Department of Neurology, Health Science Center College of Medicine, Temple, TX 76508, USA
    Phytother Res 18:706-12. 2004
  3. pmc A water extract of Mucuna pruriens provides long-term amelioration of parkinsonism with reduced risk for dyskinesias
    Christopher A Lieu
    Department of Neurology, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA
    Parkinsonism Relat Disord 16:458-65. 2010
  4. ncbi Bilateral striopallidodentate calcinosis: clinical characteristics of patients seen in a registry
    B V Manyam
    Department of Neurology, Scott and White Clinic and Memorial Hospital and Texas A and M University System Health Science Center College of Medicine, Temple, Texas 76508, USA
    Mov Disord 16:258-64. 2001
  5. ncbi Effect of antiparkinson drug HP-200 (Mucuna pruriens) on the central monoaminergic neurotransmitters
    Bala V Manyam
    Department of Neurology, Scott and White Clinic and Texas A and M University System Health Science Center College of Medicine, Temple, TX 76508, USA
    Phytother Res 18:97-101. 2004
  6. ncbi What is and what is not 'Fahr's disease'
    Bala V Manyam
    Department of Neurology, Scott and White Clinic, Plummer Movement Disorders Center, The Texas A and M University System Health Science Center College of Medicine, Temple, TX 76508, USA
    Parkinsonism Relat Disord 11:73-80. 2005
  7. ncbi Anti-Parkinson botanical Mucuna pruriens prevents levodopa induced plasmid and genomic DNA damage
    Binu Tharakan
    Department of Neurology, Scott and White Clinic, Temple, Texas, USA
    Phytother Res 21:1124-6. 2007
  8. ncbi Genetic heterogeneity in familial idiopathic basal ganglia calcification (Fahr disease)
    J R M Oliveira
    Neurogenetics Program, Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1769, USA
    Neurology 63:2165-7. 2004
  9. ncbi Trichopus zeylanicus combats fatigue without amphetamine-mimetic activity
    Binu Tharakan
    Plummer Movement Disorders Center, Department of Neurology, Scott and White Clinic, Temple, TX 76508, USA
    Phytother Res 20:165-8. 2006
  10. ncbi Botanical therapies in sexual dysfunction
    Binu Tharakan
    Plummer Movement Disorders Center, Department of Neurology, Scott and White Clinic and the Texas A and M University System, Health Science Center College of Medicine, Temple, Texas 76508, USA
    Phytother Res 19:457-63. 2005

Research Grants

Collaborators

  • Muralikrishnan Dhanasekaran
  • Z K Wszolek
  • M J Sobrido
  • R J Buchanan
  • Binu Tharakan
  • Christopher A Lieu
  • Leigh A Holcomb
  • J R M Oliveira
  • Katherine H Fiala
  • Thyagarajan Subramanian
  • Allen R Kunselman
  • Kala Venkiteswaran
  • Janna Mize-Berge
  • Mark Riggs
  • Angie R Hitt
  • Holly M Brown-Borg
  • Keith A Young
  • J Gilbert
  • D B Calne
  • J Klepper
  • S Hopfer
  • F Boller
  • E Spiteri
  • M Baquero
  • A J Stoessl
  • M Hutton
  • T Voit
  • D H Geschwind
  • Jacqueline Whetteckey

Detail Information

Publications18

  1. ncbi Malignant melanoma and levodopa in Parkinson's disease: causality or coincidence?
    Katherine H Fiala
    Department of Neurology, Texas A and M University System, Health Science Center College of Medicine, 2401 South 31st Street, Temple, TX 76508, USA
    Parkinsonism Relat Disord 9:321-7. 2003
    ..It did not appear that the Parkinson's disease patients on levodopa therapy were predisposed to melanoma, nor did levodopa therapy appear to exaggerate melanoma if it were previously present...
  2. ncbi Neuroprotective effects of the antiparkinson drug Mucuna pruriens
    Bala V Manyam
    Department of Neurology, Health Science Center College of Medicine, Temple, TX 76508, USA
    Phytother Res 18:706-12. 2004
    ....
  3. pmc A water extract of Mucuna pruriens provides long-term amelioration of parkinsonism with reduced risk for dyskinesias
    Christopher A Lieu
    Department of Neurology, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA
    Parkinsonism Relat Disord 16:458-65. 2010
    ..These unique long-term anti-parkinsonian effects of a parenterally administered water extract of M. pruriens seed powder may provide a platform for future drug discoveries and novel treatment strategies in PD...
  4. ncbi Bilateral striopallidodentate calcinosis: clinical characteristics of patients seen in a registry
    B V Manyam
    Department of Neurology, Scott and White Clinic and Memorial Hospital and Texas A and M University System Health Science Center College of Medicine, Temple, Texas 76508, USA
    Mov Disord 16:258-64. 2001
    ..This study suggests that movement disorders are the most common manifestations of BSPDC, and among movement disorders, parkinsonism outnumber others...
  5. ncbi Effect of antiparkinson drug HP-200 (Mucuna pruriens) on the central monoaminergic neurotransmitters
    Bala V Manyam
    Department of Neurology, Scott and White Clinic and Texas A and M University System Health Science Center College of Medicine, Temple, TX 76508, USA
    Phytother Res 18:97-101. 2004
    ....
  6. ncbi What is and what is not 'Fahr's disease'
    Bala V Manyam
    Department of Neurology, Scott and White Clinic, Plummer Movement Disorders Center, The Texas A and M University System Health Science Center College of Medicine, Temple, TX 76508, USA
    Parkinsonism Relat Disord 11:73-80. 2005
    ..Calcium and other mineral deposits cannot be linked to a single chromosomal locus. Further genetic studies to identify the chromosomal locus for the disease are in progress...
  7. ncbi Anti-Parkinson botanical Mucuna pruriens prevents levodopa induced plasmid and genomic DNA damage
    Binu Tharakan
    Department of Neurology, Scott and White Clinic, Temple, Texas, USA
    Phytother Res 21:1124-6. 2007
    ..It exhibited chelation of divalent copper ions in a dose-dependent manner. The copper chelating property may be one of the mechanisms by which MPCP exerts its protective effects on DNA...
  8. ncbi Genetic heterogeneity in familial idiopathic basal ganglia calcification (Fahr disease)
    J R M Oliveira
    Neurogenetics Program, Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1769, USA
    Neurology 63:2165-7. 2004
    ..The authors found evidence against linkage to IBGC1 in five of the six families supporting previous preliminary studies demonstrating genetic heterogeneity in familial IBGC...
  9. ncbi Trichopus zeylanicus combats fatigue without amphetamine-mimetic activity
    Binu Tharakan
    Plummer Movement Disorders Center, Department of Neurology, Scott and White Clinic, Temple, TX 76508, USA
    Phytother Res 20:165-8. 2006
    ..These results show that Trichopus zeylanicus whole plant powder has anti-fatigue effects in young Sprague-Dawley rats and aged normal and mutant Ames dwarf mice providing scientific evidence for the Kani tribal practice in India...
  10. ncbi Botanical therapies in sexual dysfunction
    Binu Tharakan
    Plummer Movement Disorders Center, Department of Neurology, Scott and White Clinic and the Texas A and M University System, Health Science Center College of Medicine, Temple, Texas 76508, USA
    Phytother Res 19:457-63. 2005
    ..This review, while evaluating various factors that control sexual function, identifies a variety of botanicals that may be potentially useful in treating sexual dysfunction...
  11. ncbi Neuroprotective mechanisms of ayurvedic antidementia botanical Bacopa monniera
    Muralikrishnan Dhanasekaran
    Department of Neurology, Scott and White Clinic, Texas A and M University System HSC College of Medicine, Temple, Texas, USA
    Phytother Res 21:965-9. 2007
    ....
  12. doi Centella asiatica extract selectively decreases amyloid beta levels in hippocampus of Alzheimer's disease animal model
    Muralikrishnan Dhanasekaran
    Department of Neurology, Scott and White Clinic, Texas A and M University System HSC College of Medicine, Texas, USA
    Phytother Res 23:14-9. 2009
    ....
  13. ncbi Bacopa monniera extract reduces amyloid levels in PSAPP mice
    Leigh A Holcomb
    Department of Psychiatry and Behavioral Science, Texas A and M, University System HSC College of Medicine, Temple, TX 76508, USA
    J Alzheimers Dis 9:243-51. 2006
    ..The areas encompassed by Congo Red-positive fibrillar amyloid deposits, however, were not altered by BME treatment. The data suggest that BME has potential application in Alzheimer's disease therapeutics...
  14. ncbi Antioxidant and DNA protecting properties of anti-fatigue herb Trichopus zeylanicus
    Binu Tharakan
    Department of Neurology, Scott and White Clinic and Memorial Hospital, Scott, Sherwood and Brindley Foundation, Temple, TX 76508, USA
    Phytother Res 19:669-73. 2005
    ....
  15. ncbi Botanical therapies in chronic fatigue
    Binu Tharakan
    Plummer Movement Disorders Center, Department of Neurology, Scott and White Clinic and the Texas A and M University System, HSC College of Medicine, Temple, Texas, USA
    Phytother Res 20:91-5. 2006
    ..The exploration of potential alternative therapies from traditional medicine is reviewed, as there are several botanicals with experimental evidence of efficacy based on animal models and clinical studies...
  16. ncbi Antiparkinson drug--Mucuna pruriens shows antioxidant and metal chelating activity
    Muralikrishnan Dhanasekaran
    Department of Pharmacal Sciences, Harrison School of Pharmacy, Auburn, Alabama, USA
    Phytother Res 22:6-11. 2008
    ..In addition, the drug appears to be therapeutically safe in the treatment of patients with Parkinson's disease...
  17. ncbi Diabetes mellitus, Ayurveda, and yoga
    Bala V Manyam
    J Altern Complement Med 10:223-5. 2004
  18. ncbi Analyses of nursing home residents with Parkinson's disease using the minimum data set
    Robert J Buchanan
    Department of Health Policy and Management, School of Rural Public Health, The Texas A and M University System Health Science Center, College Station, TX 77843 1266, USA
    Parkinsonism Relat Disord 8:369-80. 2002
    ..To enhance the quality of life for nursing home residents with PD, appropriate and adequate rehabilitative, mental health, and cognitive care need to be implemented...

Research Grants3

  1. Alzheimre's disease antiamyloid neuroprotective tmt
    Bala Manyam; Fiscal Year: 2003
    ..abstract_text> ..
  2. PARKINSON DISEASE NEUROPROTECTION CLINICAL TRIAL CENTER
    Bala Manyam; Fiscal Year: 2005
    ..abstract_text> ..