Research Topics
| Mitchell L SchubertSummaryCountry: USA Publications
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Publications
Gastric secretionMitchell L Schubert
Department of Medicine, Division of Gastroenterology, Virginia Commonwealth University s Medical College of Virginia, Richmond, 23249, USA
Curr Opin Gastroenterol 21:636-43. 2005..The purpose of this review is to summarize the pertinent literature published in the past year regarding the regulation of gastric exocrine and endocrine secretion...
Gastric secretionMitchell L Schubert
Department of Medicine, Division of Gastroenterology, Virginia Commonwealth University s Medical College of Virginia and McGuire Veterans Affairs Medical Center, Richmond, VA 23249, USA
Curr Opin Gastroenterol 24:659-64. 2008..This review summarizes the past year's literature regarding the regulation and assessment of gastric acid secretion...
H. pylori acutely inhibits gastric secretion by activating CGRP sensory neurons coupled to stimulation of somatostatin and inhibition of histamine secretionMuhammad Zaki
McGuire VAMC, Division of Gastroenterology code 111N, 1201 Broad Rock Blvd, Richmond, VA 23249
Am J Physiol Gastrointest Liver Physiol 304:G715-22. 2013..Activation of neural pathways provides one explanation as to how initial patchy colonization of the superficial gastric mucosa by H. pylori can acutely inhibit acid secretion...
Gastric exocrine and endocrine secretionMitchell L Schubert
Department of Medicine, Division of Gastroenterology, Virginia Commonwealth University Health System and McGuire Veterans Affairs Medical Center, Richmond, Virginia, USA
Curr Opin Gastroenterol 25:529-36. 2009..This review summarizes the last year's literature regarding the regulation and measurement of gastric exocrine and endocrine secretion...
Hormonal regulation of gastric acid secretionMitchell L Schubert
McGuire Veterans Affairs Medical Center, Code 111N, Gastroenterology Division, 1201 Broad Rock Boulevard, Richmond, VA 23249, USA
Curr Gastroenterol Rep 10:523-7. 2008..Nutrients within the intestine, mainly lipid and protein, release peptide hormones such as cholecystokinin, secretin, neurotensin, and glucagon-like peptide, which may act in concert to inhibit acid secretion...
Control of gastric acid secretion in health and diseaseMitchell L Schubert
Department of Medicine, Division of Gastroenterology, Virginia Commonwealth University s Medical College of Virginia, McGuire Veterans Affairs Medical Center, Richmond, Virginia 23249, USA
Gastroenterology 134:1842-60. 2008..We review the physiology and pathophysiology of acid secretion as well as evidence regarding its inhibition in the management of acid-related clinical conditions...
Menetrier's DiseaseNagib Toubia
Mitchell L Schubert, MD McGuire VAMC, Division of Gastroenterology 111N, 1201 Broad Rock Boulevard, Richmond, VA 23249, USA
Curr Treat Options Gastroenterol 11:103-8. 2008..More recently, therapies targeting increased signaling of the EGFR have shown promise, including somatostatin analogues and monoclonal antibodies (eg, cetuximab) directed against the EGFR. In refractory cases, gastrectomy is curative...
Gastric secretionMitchell L Schubert
Department of Medicine, Division of Gastroenterology, Virginia Commonwealth University s Medical College of Virginia and McGuire Veterans Affairs Medical Center, Richmond, Virginia 23249, USA
Curr Opin Gastroenterol 23:595-601. 2007..This review summarizes the past year's literature regarding the regulation of gastric exocrine and endocrine secretion...
Treatment of gastric carcinoidsWei Hou
Mitchell L Schubert, MD McGuire VAMC, Division of Gastroenterology 111N, 1201 Broad Rock Boulevard, Richmond, VA 23249, USA
Curr Treat Options Gastroenterol 10:123-33. 2007..Antrectomy, by eliminating the trophic effect of gastrin, can be useful for select type I carcinoids. Long-acting somatostatin analogues are excellent palliative agents...
Adrenomedullin stimulates somatostatin and thus inhibits histamine and acid secretion in the fundus of the stomachAri B Hirsch
Department of Medicine, Medical College of Virginia Virginia Commonwealth University, Richmond, VA, USA
Regul Pept 110:189-95. 2003..This represents one mechanism by which adrenomedullin might enhance mucosal defense and repair...
Gastric secretionWei Hou
Department of Medicine, Division of Gastroenterology, Virginia Commonwealth University's Medical College of Virginia and McGuire Veterans Affairs Medical Center, Richmond, Virginia 23249, USA
Curr Opin Gastroenterol 22:593-8. 2006....
Gastric secretionShijian Chu
McGuire Veterans Affairs Medical Center, Richmond, Virginia 23249, USA
Curr Opin Gastroenterol 28:587-93. 2012..This review summarizes the past year's literature regarding the regulation of gastric exocrine and endocrine secretion, both basic science and clinical...
Amylin, released from the gastric fundus, stimulates somatostatin and thus inhibits histamine and acid secretion in miceMuhammad Zaki
Department of Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia, USA
Gastroenterology 123:247-55. 2002..CONCLUSIONS: In gastric fundus, release of amylin from somatostatin cells interacts with distinct amylin receptors to enhance somatostatin secretion via an autocrine pathway that leads to inhibition of histamine and acid secretion...
