Research Topics
| Gregory S MerrickSummaryAffiliation: Schiffler Cancer Center Country: USA Publications
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Detail Information
Publications
Prognostic significance of perineural invasion on biochemical progression-free survival after prostate brachytherapyGregory S Merrick
Schiffler Cancer Center, USA
Urology 66:1048-53. 2005..To evaluate the influence of perineural invasion (PNI) in the biopsy specimen on biochemical progression-free survival in hormone-naive patients with prostate cancer undergoing brachytherapy...
The impact of primary Gleason grade on biochemical outcome following brachytherapy for hormone-naive Gleason score 7 prostate cancerGregory S Merrick
Schiffler Cancer Center Wheeling Jesuit University, Wheeling, West Virginia, USA
Cancer J 11:234-40. 2005..In this study, we evaluate the effect of the dominant histologic pattern in Gleason score 7 prostate cancer on biochemical progression-free survival after brachytherapy...
Prostate cryotherapy: more questions than answersGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, Wheeling, West Virginia 26003-6300, USA
Urology 66:9-15. 2005
Erectile function after prostate brachytherapyGregory S Merrick
Schiffler Cancer Center, Wheeling, WV 26003, USA
Int J Radiat Oncol Biol Phys 62:437-47. 2005..To evaluate erectile function after permanent prostate brachytherapy using a validated patient-administered questionnaire and to determine the effect of multiple clinical, treatment, and dosimetric parameters on penile erectile function...
The impact of radiation dose to the urethra on brachytherapy-related dysuriaGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, Wheeling, WV 26003 6300, USA
Brachytherapy 4:45-50. 2005..To determine the effect of urethral dose on dysuria after permanent prostate brachytherapy...
Variability of prostate brachytherapy pre-implant dosimetry: a multi-institutional analysisGregory S Merrick
Schiffler Cancer Center and Wheeling Jesuit University, Wheeling, WV 26003 6300, USA
Brachytherapy 4:241-51. 2005..To conduct a multi-institutional comparison of prostate brachytherapy pre-implant dosimetry of Pd-103 and I-125...
Risk factors for the development of prostate brachytherapy related urethral stricturesGregory S Merrick
Schiffler Cancer Center and Wheeling Jesuit University, Wheeling, West Virginia, USA
J Urol 175:1376-80; discussion 1381. 2006..We identified clinical, treatment and dosimetric parameters associated with the development of urethral strictures following permanent prostate brachytherapy...
Androgen-deprivation therapy does not impact cause-specific or overall survival after permanent prostate brachytherapyGregory S Merrick
Schiffler Cancer Center, Wheeling Jesuit University, Wheeling, WV, USA
Int J Radiat Oncol Biol Phys 65:669-77. 2006..To determine if androgen-deprivation therapy (ADT) has an impact on cause-specific, biochemical progression-free, or overall survival after prostate brachytherapy...
Influence of body mass index on biochemical outcome after permanent prostate brachytherapyGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, Wheeling, West Virginia 26003 6300, USA
Urology 65:95-100. 2005..To evaluate the impact of body mass index (BMI) on the 8-year biochemical outcome after permanent prostate brachytherapy with or without the addition of supplemental external beam radiotherapy and/or androgen deprivation therapy (ADT)...
The impact of prostate volume and neoadjuvant androgen-deprivation therapy on urinary function following prostate brachytherapyGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, 1 Medical Park, Wheeling, WV 26003 6300, USA
Cancer J 10:181-9. 2004....
Permanent prostate brachytherapy: is supplemental external-beam radiation therapy necessary?Gregory S Merrick
Schiffler Cancer Center, Wheeling Jesuit University, Wheeling, West Virginia 26003 6300, USA
Oncology (Williston Park) 20:514-22; discussion 522-5. 2006..The completion of ongoing prospective randomized trials will help define the role of XRT as a supplement to permanent prostate brachytherapy...
Efficacy of neoadjuvant bicalutamide and dutasteride as a cytoreductive regimen before prostate brachytherapyGregory S Merrick
Schiffler Cancer Center and Wheeling Jesuit University, Wheeling Hospital, Wheeling, West Virginia 26003 6300, USA
Urology 68:116-20. 2006..To evaluate the cytoreductive effectiveness of combined neoadjuvant bicalutamide and dutasteride before prostate brachytherapy for clinically localized prostate cancer...
The effect of hormonal manipulation on urinary function following permanent prostate brachytherapyGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, Wheeling, WV 26003 6300, USA
Brachytherapy 3:22-9. 2004..To evaluate the effect of hormonal manipulation on catheter dependency, the resolution of urinary symptomatology, and the need for postbrachytherapy transurethral/transincisional resection (TURP/TUIP)...
Impact of supplemental external beam radiotherapy and/or androgen deprivation therapy on biochemical outcome after permanent prostate brachytherapyGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, Wheeling, WV 26003, USA
Int J Radiat Oncol Biol Phys 61:32-43. 2005..To evaluate the impact of supplemental external beam radiotherapy (EBRT) and/or androgen deprivation therapy (ADT) on 8-year biochemical outcome after permanent prostate brachytherapy...
Temporal effect of neoadjuvant androgen deprivation therapy on PSA kinetics following permanent prostate brachytherapy with or without supplemental external beam radiationGregory S Merrick
Department of Radiation Oncology, Schiffler Cancer Center, Wheeling Hospital, 1 Medical Park, Wheeling, WV 26003 6300, USA
Brachytherapy 3:141-6. 2004....
Androgen deprivation-induced changes in prostate anatomy predict urinary morbidity after permanent interstitial brachytherapyAshley Hinerman-Mulroy
Schiffler Cancer Center, Wheeling Hospital, 1 Medical Park, Wheeling, WV 26003-6300, USA
Int J Radiat Oncol Biol Phys 59:1367-82. 2004....
Primary causes of death after permanent prostate brachytherapyNathan Bittner
Department of Radiation Oncology, University of Washington, Seattle, WA 26003 6300, USA
Int J Radiat Oncol Biol Phys 72:433-40. 2008..To evaluate the primary causes of death in low-risk (low-risk), intermediate-risk (intermediate-risk), and high-risk (high-risk) patients undergoing permanent prostate brachytherapy with or without supplemental therapies...
Permanent interstitial brachytherapy in younger patients with clinically organ-confined prostate cancerGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, Wheeling, West Virginia 26003-6300, USA
Urology 64:754-9. 2004..CONCLUSIONS: Hormone-naive patients 62 years of age or younger have a high probability of 7-year biochemical progression-free survival after permanent interstitial brachytherapy with or without supplemental external beam radiotherapy...
Severity categories of the International Prostate Symptom Score before, and urinary morbidity after, permanent prostate brachytherapySarah Gutman
Schiffler Cancer Center, Wheeling Hospital, Wheeling, WV 26003, USA
BJU Int 97:62-8. 2006..At 5 years after brachytherapy, 90.1% of patients at risk were assigned to the IPSS 0-7 category...
Permanent prostate brachytherapy-induced morbidity in patients with grade II and III obesityGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, Wheeling, West Virginia 26003-6300, USA
Urology 60:104-8. 2002..In addition, the dosimetric quality of the implants was outstanding, and the short-term biochemical outcome was encouraging...
Monotherapeutic brachytherapy for clinically organ-confined prostate cancerGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, USA
W V Med J 101:168-71. 2005..1 ng/mL. Generous periprostatic treatment margins with documented high quality day 0 postoperative dosimetry are mandatory for such outcomes...
Long-term outcome for clinically localized prostate cancer treated with permanent interstitial brachytherapyAl V Taira
Department of Radiation Oncology, University of Washington, Seattle, Washington, USA
Int J Radiat Oncol Biol Phys 79:1336-42. 2011..To present the largest series of prostate cancer brachytherapy patients treated with modern brachytherapy techniques and postimplant day 0 dosimetric evaluation...
Prophylactic versus therapeutic alpha-blockers after permanent prostate brachytherapyGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, Wheeling, West Virginia 26003-6300, USA
Urology 60:650-5. 2002..In patients receiving prophylactic alpha-blockers, the IPSS normalized significantly faster but had no impact on urinary retention or the ultimate need for postimplant surgical intervention...
Biochemical and functional outcomes following brachytherapy with or without supplemental therapies in men < or = 50 years of age with clinically organ-confined prostate cancerGregory S Merrick
Schiffler Cancer Center, Wheeling Jesuit University, Wheeling, WV 26003 6300, USA
Am J Clin Oncol 31:539-44. 2008..Herein, we report cause-specific survival, biochemical progression-free survival (bPFS), overall survival and functional outcomes in men < or =50 years of age who underwent brachytherapy with or without supplemental therapies...
Effects of the time interval between prostate brachytherapy and postimplant dosimetric evaluation in community practice: analysis of the Pro-Qura databasePeter F Orio
Department of Radiation Oncology, Brooke Army Medical Center, Ft Sam Houston, TX, USA
Am J Clin Oncol 31:523-31. 2008..To evaluate the influence of postimplant dosimetric timing on prostate brachytherapy quality in community practice...
Permanent prostate brachytherapy in prostate glands <20 cm(3)Jyoti Mayadev
Department of Radiation Oncology, University of Washington, Seattle, WA, USA
Int J Radiat Oncol Biol Phys 76:1450-5. 2010..To investigate the dosimetry, treatment-related morbidity, and biochemical outcomes for brachytherapy in patients with prostate glands <20 cm(3)...
Detailed urethral dosimetry in the evaluation of prostate brachytherapy-related urinary morbidityZachariah A Allen
Schiffler Cancer Center, Wheeling Hospital, 1 Medical Park, Wheeling, WV 26003-6300, USA
Int J Radiat Oncol Biol Phys 62:981-7. 2005..Radiation doses of 100%-140% minimum peripheral dose are well tolerated by all segments of the prostatic urethra with resultant tumoricidal doses to foci of periurethral cancer...
Obesity is not predictive of overall survival following permanent prostate brachytherapyGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, Wheeling Jesuit University, Wheeling, West Virginia 26003 6300, USA
Am J Clin Oncol 30:588-96. 2007..To evaluate the impact of obesity on cause-specific (CSS), biochemical progression-free (bPFS), and overall survival (OS) following prostate brachytherapy...
Dosimetry of an extracapsular anulus following permanent prostate brachytherapyGregory S Merrick
Schiffler Cancer Center, Wheeling Jesuit University, Wheeling, WV, USA
Am J Clin Oncol 30:228-33. 2007..It is likely that volumetric geographic dosimetric parameters will be more robust than selected radial measurements. Accordingly, we evaluated extracapsular volumetric dosimetric parameters in low-risk patients...
Isotope and patient age predict for PSA spikes after permanent prostate brachytherapyChelsea Bostancic
Schiffler Cancer Center, Wheeling Jesuit University, Wheeling, WV 26003 6300, USA
Int J Radiat Oncol Biol Phys 68:1431-7. 2007..To evaluate prostate-specific antigen (PSA) spikes after permanent prostate brachytherapy in low-risk patients...
Influence of Pro-Qura-generated plans on postimplant dosimetric quality: a review of a multi-institutional databaseZachariah Allen
Wheeling Hospital, Schiffler Cancer Center, Wheeling, WV Wheeling Jesuit University, Wheeling, WV Seattle Prostate Institute, Seattle, WA and Pro Qura, Seattle, WA
Med Dosim 33:206-14. 2008..It is possible that the Pro-Qura plan and/or the routine postimplant dosimetric evaluation may have influenced dosimetric outcomes at community-based centers...
Effect of cigarette smoking on biochemical outcome after permanent prostate brachytherapyGregory S Merrick
Schiffer Cancer Center, Wheeling Hospital, and Wheeling Jesuit University, WV 26003 6300, USA
Int J Radiat Oncol Biol Phys 58:1056-62. 2004..In this study, we evaluated the effect of cigarette smoking on the presentation and biochemical outcome after permanent prostate brachytherapy for prostate cancer...
Optimal equations for describing the relationship between prostate volume, number of sources, and total activity in permanent prostate brachytherapyJesse N Aronowitz
Department of Radiation Oncology, University of Massachusetts Medical School, Worcester, MA, USA
Am J Clin Oncol 33:164-7. 2010..To determine whether there is an optimal type of mathematical equation for predicting seed and activity requirements for permanent prostate brachytherapy...
Long-term urinary quality of life after permanent prostate brachytherapyGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, Wheeling, WV 26003, USA
Int J Radiat Oncol Biol Phys 56:454-61. 2003..To evaluate late urinary function after permanent prostate brachytherapy using a validated, patient-administered quality-of-life instrument...
Prebiopsy PSA velocity not reliable predictor of prostate cancer diagnosis, Gleason score, tumor location, or cancer volume after TTMBNathan Bittner
Department of Radiation Oncology, University of Washington, Seattle, Washington, USA
Urology 74:171-6. 2009..PSAV has been associated with greater Gleason scores and greater prostate cancer-specific mortality...
Relationship between percent positive biopsies and biochemical outcome after permanent interstitial brachytherapy for clinically organ-confined carcinoma of the prostate glandGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, WV 26003 6300, USA
Int J Radiat Oncol Biol Phys 52:664-73. 2002....
The influence of isotope and prostate volume on urinary morbidity after prostate brachytherapyAngela Niehaus
Schiffler Cancer Center and Department of Physics, Wheeling Jesuit University, Wheeling, WV 26003-6300, USA
Int J Radiat Oncol Biol Phys 64:136-43. 2006..Although prostate size did predict for short-term (<5 days) catheter dependency, it did not influence IPSS resolution or the need for surgical intervention...
High-risk prostate cancer with Gleason score 8-10 and PSA level ≤15 ng/mL treated with permanent interstitial brachytherapyL Christine Fang
Department of Radiation Oncology, University of Washington, Seattle, WA, USA
Int J Radiat Oncol Biol Phys 81:992-6. 2011....
Prognostic significance of percent positive biopsies in clinically organ-confined prostate cancer treated with permanent prostate brachytherapy with or without supplemental external-beam radiationGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, Wheeling, West Virginia 26003 6300, USA
Cancer J 10:54-60. 2004....
Erectile function after permanent prostate brachytherapyGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, Wheeling, WV 26003 6300, USA
Int J Radiat Oncol Biol Phys 52:893-902. 2002....
Biochemical outcome for hormone-naïve patients with high-risk prostate cancer managed with permanent interstitial brachytherapy and supplemental external-beam radiationGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, West Virginia 26003-6300, USA
Cancer J 8:322-7. 2002....
Biochemical outcome for hormone-naive patients with Gleason score 3+4 versus 4+3 prostate cancer undergoing permanent prostate brachytherapyGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, Wheeling, West Virginia 26003-6300, USA
Urology 60:98-103. 2002..CONCLUSIONS: Our results indicate that the 5-year biochemical outcome with a hormone-naive prostate brachytherapy approach that uses multiple periprostatic seeds is not dependent on Gleason score 3+4 versus 4+3 histologic features...
20 Gy versus 44 Gy of supplemental external beam radiotherapy with palladium-103 for patients with greater risk disease: results of a prospective randomized trialGregory S Merrick
Schiffler Cancer Center Wheeling Jesuit University, Wheeling, WV 26003, USA
Int J Radiat Oncol Biol Phys 82:e449-55. 2012..We report brachytherapy outcomes for patients with higher risk features randomized to substantially different supplemental EBRT regimens...
The importance of radiation doses to the penile bulb vs. crura in the development of postbrachytherapy erectile dysfunctionGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, 1 Medical Park, Wheeling, WV 26003 6300, USA
Int J Radiat Oncol Biol Phys 54:1055-62. 2002..In this study, we evaluated by means of a validated patient-administered questionnaire whether radiation doses to the bulb of the penis and/or the proximal corporeal bodies were predictive for the development of brachytherapy-induced ED...
Prostate cancer death is unlikely in high-risk patients following quality permanent interstitial brachytherapyGregory S Merrick
Schiffler Cancer Center, Wheeling Jesuit University, Wheeling, WV, USA
BJU Int 107:226-32. 2011..To evaluate cause-specific survival (CSS), biochemical progression-free survival (bPFS) and overall survival (OS) in high-risk prostate cancer brachytherapy patients...
The dosimetry of prostate brachytherapy-induced urethral stricturesGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, Wheeling, WV 26003 6300, USA
Int J Radiat Oncol Biol Phys 52:461-8. 2002..In this study, we evaluate multiple clinical, treatment, and dosimetric parameters to identify factors associated with the development of brachytherapy-induced urethral strictures...
Androgen deprivation therapy does not impact cause-specific or overall survival in high-risk prostate cancer managed with brachytherapy and supplemental external beamGregory S Merrick
Schiffler Cancer Center, Wheeling Jesuit University, Wheeling, WV, USA
Int J Radiat Oncol Biol Phys 68:34-40. 2007..To determine cause-specific survival (CSS), biochemical progression-free survival (bPFS), and overall survival (OS) in high-risk prostate cancer patients undergoing brachytherapy with or without supplemental therapies...
Postimplant rectal dosimetry is not dependent on 103Pd or 125I seed activityGregory S Merrick
Schiffler Cancer Center and Wheeling Jesuit University, 1 Medical Park, Wheeling, WV 26003, USA
Brachytherapy 10:35-43. 2011..In this study, the effect of prostate brachytherapy seed activity on postimplant rectal dosimetry was evaluated in Pro-Qura (Prostate Brachytherapy Quality Assurance; Seattle, WA) proctored, community-based programs...
Minimizing prostate brachytherapy-related morbidityGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, Wheeling, West Virginia 26003-6300, USA
Urology 62:786-92. 2003
Influence of hormonal therapy on late rectal function after permanent prostate brachytherapy with or without supplemental external beam radiotherapyGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, Wheeling, WV 26003 6300, USA
Int J Radiat Oncol Biol Phys 58:68-74. 2004..Using a patient-administered quality-of-life instrument, we evaluated the effect of hormonal therapy on late rectal function after permanent prostate brachytherapy with or without supplemental external beam radiotherapy...
Factors impacting all-cause mortality in prostate cancer brachytherapy patients with or without androgen deprivation therapyAl V Taira
Department of Radiation Oncology, University of Washington, Seattle, WA, USA
Brachytherapy 9:42-9. 2010..We evaluated the relationship between pretreatment serum testosterone, age, and comorbidities on survival after prostate brachytherapy in men treated with and without ADT...
Brachytherapy-related dysuriaGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, Wheeling, WV 26003 6300, USA
BJU Int 95:597-602. 2005..To evaluate the incidence and temporal resolution of dysuria after permanent prostate brachytherapy, and to identify predictors of brachytherapy-related dysuria...
Analysis of the Pro-Qura Database: rectal dose, implant quality, and brachytherapist's experienceChristopher R Loiselle
Department of Radiation Oncology, University of Washington Medical Center, Seattle, WA, USA
Brachytherapy 8:34-9. 2009....
Prostate cancer distribution in patients diagnosed by transperineal template-guided saturation biopsyGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital and Wheeling Jesuit University, Wheeling, WV 26003 6300, USA
Eur Urol 52:715-23. 2007..To determine the prostate cancer incidence, anatomic distribution, Gleason score profile, and tumor burden in patients diagnosed by transperineal template-guided saturation biopsy (TTSB)...
Long-term rectal function after permanent prostate brachytherapyGregory S Merrick
Schiffler Cancer Center, Wheeling Jesuit University, Wheeling, WV 26003 6300, USA
Cancer J 13:95-104. 2007..To evaluate the effect of prostate brachytherapy with or without supplemental therapies on long-term rectal function by means of a patient-administered quality-of-life instrument...
Prostate cancer control and survival in Vietnam veterans exposed to Agent OrangeLydia Everly
Schiffler Cancer Center and Wheeling Jesuit University, Wheeling, WV, USA
Brachytherapy 8:57-62. 2009..In this study, we evaluated the impact of Agent Orange exposure on survival in Vietnam Veterans undergoing prostate brachytherapy...
The morbidity of transperineal template-guided prostate mapping biopsyGregory S Merrick
Schiffler Cancer Center and Wheeling Jesuit University, Wheeling, WV 26003 6300, USA
BJU Int 101:1524-9. 2008..To evaluate the effect of transperineal template-guided prostate mapping biopsy (TTMB) on urinary, bowel and erectile function...
Natural history of clinically staged low- and intermediate-risk prostate cancer treated with monotherapeutic permanent interstitial brachytherapyAl V Taira
Department of Radiation Oncology, University of Washington, Seattle, WA, USA
Int J Radiat Oncol Biol Phys 76:349-54. 2010..To evaluate the natural history of clinically staged low- and intermediate-risk prostate cancer treated with permanent interstitial seed implants as monotherapy...
Androgen deprivation therapy: a survival benefit or detriment in men with high-risk prostate cancer?L Christine Fang
Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
Oncology (Williston Park) 24:790-6, 798. 2010....
Nursing considerations in brachytherapy-related erectile dysfunctionRobin Stipetich
Schiffler Cancer Center, Wheeling, WV, USA
Urol Nurs 25:249-54; quiz 259. 2005..The majority of patients with brachytherapy-induced ED respond favorably to oral erectogenic agents...
Initial analysis of Pro-Qura: a multi-institutional database of prostate brachytherapy dosimetryGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, Wheeling, WV 26003 6300, USA
Brachytherapy 6:9-15. 2007..The study aimed to analyze the Pro-Qura database in terms of patient implant sequence number for each institution to determine evidence for a dosimetric learning curve...
Brachytherapy in men aged < or = 54 years with clinically localized prostate cancerGregory S Merrick
Schiffler Cancer Center, Wheeling Jesuit University, Wheeling Hospital, Wheeling, WV 26003 6300, USA
BJU Int 98:324-8. 2006....
Dysuria after permanent prostate brachytherapyGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, Wheeling, WV 26003, USA
Int J Radiat Oncol Biol Phys 55:979-85. 2003..In this study, we evaluated the incidence and temporal resolution of dysuria, along with the influence of multiple treatment, clinical, and dosimetric parameters...
The role of hormonal therapy in prostate brachytherapy. CounterpointGregory S Merrick
Schiffler Cancer Center, Wheeling, WV, USA
Brachytherapy 2:2-4. 2003
Treatment margins predict biochemical outcomes after prostate brachytherapySeungtaek Choi
Department of Radiation Oncology, University of Washington, Seattle, WA, USA
Cancer J 10:175-80. 2004..Efforts to better identify and test geographic dosimetric parameters are theoretically appealing, and supported by the clinical data summarized here...
Late rectal function after prostate brachytherapyGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, and Wheeling Jesuit University, Wheeling, WV 26003 6300, USA
Int J Radiat Oncol Biol Phys 57:42-8. 2003..Using a patient-administered quality of life instrument, to evaluate the effect of permanent prostate brachytherapy on late rectal function...
Interstitial implant alone or in combination with external beam radiation therapy for intermediate-risk prostate cancer: a survey of practice patterns in the United StatesSteven J Frank
Department of Radiation Oncology, The University of Texas, M D Anderson Cancer Center, Houston, TX 77030, USA
Brachytherapy 6:2-8. 2007..This study is aimed at understanding and defining the current patterns of care with respect to prostate brachytherapy for patients with intermediate-risk localized disease in the combined academic and community setting...
Prostate brachytherapy in men > or =75 years of ageGregory S Merrick
Schiffler Cancer Center and Wheeling Jesuit University, Wheeling, WV 26003 6300, USA
Int J Radiat Oncol Biol Phys 72:415-20. 2008..To evaluate cause-specific survival (CSS), biochemical progression-free survival (bPFS), and overall survival (OS) in prostate cancer patients aged > or =75 years undergoing brachytherapy with or without supplemental therapies...
A detailed radiobiological and dosimetric analysis of biochemical outcomes in a case-control study of permanent prostate brachytherapy patientsWayne M Butler
Schiffier Cancer Center, Wheeling Hospital, 1 Medical Park, Wheeling, West Virginia 26003 6300, USA
Med Phys 36:776-87. 2009..This may indicate that in our approach, implant dosimetry is at or near the limits of clinically effective dose escalation...
Rectal function following brachytherapy with or without supplemental external beam radiation: results of two prospective randomized trialsGregory S Merrick
Department of Radiation Oncology, Schiffler Cancer Center, Wheeling Hospital, Wheeling, WV 26003 6300, USA
Brachytherapy 2:147-57. 2003..To evaluate the effect of isotope and supplemental external beam radiation therapy (XRT) on brachytherapy-related rectal morbidity, using prospective, patient-administered quality of life (QOL) assessments...
Rectal function following permanent prostate brachytherapyGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, Wheeling, USA
W V Med J 100:18-20. 2004..The continued elucidation of the etiology of bowel dysfunction should result in refinements in implant technique and decreased brachytherapy-related morbidity...
Effect of transurethral resection on urinary quality of life after permanent prostate brachytherapyGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, Wheeling, WV 26003 6300, USA
Int J Radiat Oncol Biol Phys 58:81-8. 2004..To determine the effect of transurethral resection on urinary function after permanent prostate brachytherapy using a validated, patient-administered, quality-of-life (QOL) instrument...
Patient selection for prostate brachytherapy: more myth than factGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, Wheeling Jesuit University, Wheeling, West Virginia 26003 6300, USA
Oncology (Williston Park) 18:445-52; discussion 452, 455-7. 2004..Refinements in patient selection may result in further improvements in biochemical and quality-of-life outcomes. Herein, we have summarized evidence-based vs unsubstantiated patient selection factors that affect outcome...
Temporal relationship between prostate brachytherapy and the diagnosis of colorectal cancerSarah A Gutman
Schiffler Cancer Center and Wheeling Jesuit University, Wheeling, WV 26003, USA
Int J Radiat Oncol Biol Phys 66:48-55. 2006..In addition, the vast majority of postbrachytherapy colorectal polyps were located beyond the confines of the rectum...
Permanent interstitial brachytherapy for clinically organ-confined high-grade prostate cancer with a pretreatment PSA < 20 ng/mLGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, Wheeling, West Virginia 26003 6300, USA
Am J Clin Oncol 27:611-5. 2004....
Myths and fallacies in permanent prostate brachytherapyWayne M Butler
Schiffler Cancer Center, Wheeling Hospital, Wheeling, WV 26003 6300, USA
Med Dosim 28:155-65. 2003..Most of the urinary morbidity and a significant part of the decrease in sexual function observed may be avoided by controlling the dosimetry along the prostatic and membranous urethra and at the penile bulb...
Factors affecting patient selection for prostate brachytherapy: what nurses should knowDebra Zeroski
Clin J Oncol Nurs 9:553-60. 2005..Clinical studies seek to further define patient selection criteria and examine optimal choices for adjuvant treatment and isotope preference. Expanding the knowledge base of nurses helps enhance patient care...
Clinical practice and quality assurance challenges in modern brachytherapy sources and dosimetryWayne M Butler
Schiffler Cancer Center, Wheeling Hospital and Wheeling Jesuit University, Wheeling, WV 26003 6300, USA
Int J Radiat Oncol Biol Phys 71:S142-6. 2008..The changing environment of brachytherapy has not changed the fact that the prime responsibility for quality assurance in brachytherapy lies with the institutional medical physicist...
Prostate-specific antigen (PSA) velocity and benign prostate hypertrophy predict for PSA spikes following prostate brachytherapyGregory S Merrick
Department of Radiation Oncology, Schiffler Cancer Center, Wheeling Hospital, Wheeling, WV 26003 6300, USA
Brachytherapy 2:181-8. 2003..To evaluate if variants of serum PSA or benign prostatic hypertrophy correlate with the development of a PSA spike following permanent prostate brachytherapy...
Nursing assessment of sexual function following permanent prostate brachytherapy for patients with early-stage prostate cancerRobin L Stipetich
Clin J Oncol Nurs 6:271-4. 2002..Fortunately, the majority of patients with brachytherapy-induced ED respond favorably to sildenafil citrate...
American Brachytherapy Society recommendations for reporting morbidity after prostate brachytherapySubir Nag
American Brachytherapy Society, Oakbrook, IL, USA
Int J Radiat Oncol Biol Phys 54:462-70. 2002..To standardize the reporting of brachytherapy-related prostate morbidity to guide ongoing clinical practice and future investigations...
Treatment outcomes and quality-of-life issues for patients treated with prostate brachytherapyLaurie Abel
Clin J Oncol Nurs 7:48-54. 2003..Armed with knowledge about prostate brachytherapy and its effect on QOL, oncology nurses can offer accurate information and evidence-based symptom management techniques to patients undergoing brachytherapy for prostate cancer...
A prospective randomized comparison of stranded vs. loose 125I seeds for prostate brachytherapyDaniel R Reed
Scottsdale Radiation Oncology, Arizona Oncology Services, Phoenix, AZ 85260, USA
Brachytherapy 6:129-34. 2007..To compare seed loss and dosimetric parameters between stranded and loose 125I seeds (LS) for prostate brachytherapy...
Extracapsular radiation dose distribution after permanent prostate brachytherapyGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, Wheeling, West Virginia 26003 6300, USA
Am J Clin Oncol 26:e178-89. 2003..The extent of the postimplant periprostatic margin (6.5 +/- 1.8 mm) satisfies the preplanning margin criterion of >5 mm...
Cholesterol, cholesterol-lowering agents/statins, and urologic disease: Part V--Statins versus aspirin for primary prevention, and the winner is...?Mark A Moyad
University of Michigan Medical Center, Department of Urology, Ann Arbor, MI, USA
Urol Nurs 27:166-8. 2007..In addition, patients should be informed about the recent observational data suggesting that statins may reduce mortality from other causes such as prostate cancer...
Statins, especially atorvastatin, may improve survival following brachytherapy for clinically localized prostate cancerMark A Moyad
University of Michigan Medical Center, Department of Urology, Ann Arbor, MI, USA
Urol Nurs 26:298-303. 2006..A prospective trial of statin medications in conjunction with definitive local treatment for prostate cancer is recommended...
American Brachytherapy Society recommends no change for prostate permanent implant dose prescriptions using iodine-125 or palladium-103Mark J Rivard
Departments of Radiation Oncology and Medical Physics, Tufts New England Medical Center, Boston, MA 02111, USA
Brachytherapy 6:34-7. 2007..Consequently, the American Brachytherapy Society (ABS) considered the nature of these changes towards issuing recommended dose prescriptions for 125I and 103Pd interstitial brachytherapy implants for monotherapy and standard boosts...
