Larisa Reyderman

Summary

Affiliation: Schering-Plough Research Institute
Country: USA

Publications

  1. ncbi request reprint Pharmacokinetic interaction between ezetimibe and lovastatin in healthy volunteers
    Larisa Reyderman
    Department of Drug Metabolism and Pharmacokinetics, Schering Plough Research Institute, Kenilworth, NJ 07033 1300, USA
    Curr Med Res Opin 20:1493-500. 2004
  2. ncbi request reprint The effect of fluvastatin on the pharmacokinetics and pharmacodynamics of ezetimibe
    Larisa Reyderman
    Drug Metabolism and Pharmacokinetics, Schering Plough Research Institute, Kenilworth, NJ 07033 1300, USA
    Curr Med Res Opin 21:1171-9. 2005
  3. ncbi request reprint Disposition and pharmacokinetics of temozolomide in rat
    L Reyderman
    Drug Metabolism and Pharmacokinetics, Schering Plough Research Institute, Kenilworth, NJ 07033 1300, USA
    Xenobiotica 34:487-500. 2004
  4. ncbi request reprint Assessment of a multiple-dose drug interaction between ezetimibe, a novel selective cholesterol absorption inhibitor and gemfibrozil
    L Reyderman
    Department of Drug Metabolism and Pharmacokinetics, Schering Plough Research Institute, Kenilworth, NJ 07033 1300, USA
    Int J Clin Pharmacol Ther 42:512-8. 2004
  5. ncbi request reprint Pharmacodynamic and pharmacokinetic interaction between fenofibrate and ezetimibe
    Teddy Kosoglou
    Department of Early Clinical Research and Experimental Medicine, Schering Plough Research Institute, Kenilworth, NJ 07033, USA
    Curr Med Res Opin 20:1197-207. 2004
  6. ncbi request reprint The toxicity of SCH 351591, a novel phosphodiesterase-4 inhibitor, in Cynomolgus monkeys
    Patricia E Losco
    Schering Plough Research Institute, Lafayette, New Jersey 07848, USA
    Toxicol Pathol 32:295-308. 2004
  7. ncbi request reprint Lack of clinically relevant interaction between desloratadine and erythromycin
    Christopher Banfield
    Department of Clinical Pharmacology, Schering Plough Research Institute, Kenilworth, New Jersey 07033 0539, USA
    Clin Pharmacokinet 41:29-35. 2002
  8. ncbi request reprint Validation of a sensitive and automated 96-well solid-phase extraction liquid chromatography-tandem mass spectrometry method for the determination of desloratadine and 3-hydroxydesloratadine in human plasma
    Liyu Yang
    Schering Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ 07033 1300, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 792:229-40. 2003
  9. ncbi request reprint Administration of an antagonist of neurokinin receptors 1, 2, and 3 results in reproductive tract changes in beagle dogs, but not rats
    Patricia E Losco
    Schering Plough Research Institute, Lafayette, NJ 07848, USA
    Toxicol Pathol 35:310-22. 2007
  10. ncbi request reprint Effects of ezetimibe on cyclosporine pharmacokinetics in healthy subjects
    Arthur J Bergman
    Merck Research Laboratories, West Point, PA 19486, USA
    J Clin Pharmacol 46:321-7. 2006

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Pharmacokinetic interaction between ezetimibe and lovastatin in healthy volunteers
    Larisa Reyderman
    Department of Drug Metabolism and Pharmacokinetics, Schering Plough Research Institute, Kenilworth, NJ 07033 1300, USA
    Curr Med Res Opin 20:1493-500. 2004
    ..The current study was designed to further investigate the potential for pharmacokinetic interaction between ezetimibe and lovastatin...
  2. ncbi request reprint The effect of fluvastatin on the pharmacokinetics and pharmacodynamics of ezetimibe
    Larisa Reyderman
    Drug Metabolism and Pharmacokinetics, Schering Plough Research Institute, Kenilworth, NJ 07033 1300, USA
    Curr Med Res Opin 21:1171-9. 2005
    ....
  3. ncbi request reprint Disposition and pharmacokinetics of temozolomide in rat
    L Reyderman
    Drug Metabolism and Pharmacokinetics, Schering Plough Research Institute, Kenilworth, NJ 07033 1300, USA
    Xenobiotica 34:487-500. 2004
    ..Temozolomide was rapidly eliminated (t(1/2) = 1.2 h) and converted to MTIC. 4. Systemic exposure to MTIC was about 2% that of temozolomide. Overall, the disposition of temozolomide in rats was similar to that observed in humans...
  4. ncbi request reprint Assessment of a multiple-dose drug interaction between ezetimibe, a novel selective cholesterol absorption inhibitor and gemfibrozil
    L Reyderman
    Department of Drug Metabolism and Pharmacokinetics, Schering Plough Research Institute, Kenilworth, NJ 07033 1300, USA
    Int J Clin Pharmacol Ther 42:512-8. 2004
    ..The objective of this study was to evaluate the potential for a pharmacokinetic (PK) interaction between ezetimibe and gemfibrozil...
  5. ncbi request reprint Pharmacodynamic and pharmacokinetic interaction between fenofibrate and ezetimibe
    Teddy Kosoglou
    Department of Early Clinical Research and Experimental Medicine, Schering Plough Research Institute, Kenilworth, NJ 07033, USA
    Curr Med Res Opin 20:1197-207. 2004
    ..The pharmacodynamic, pharmacokinetic, and safety profiles of ezetimibe and fenofibrate were evaluated alone and after co-administration in 32 subjects with primary hypercholesterolemia...
  6. ncbi request reprint The toxicity of SCH 351591, a novel phosphodiesterase-4 inhibitor, in Cynomolgus monkeys
    Patricia E Losco
    Schering Plough Research Institute, Lafayette, New Jersey 07848, USA
    Toxicol Pathol 32:295-308. 2004
    ..The findings of this study demonstrate the potential of a PDE4 inhibitor to alter immunologic response as well as to produce arteriopathy in nonhuman primates...
  7. ncbi request reprint Lack of clinically relevant interaction between desloratadine and erythromycin
    Christopher Banfield
    Department of Clinical Pharmacology, Schering Plough Research Institute, Kenilworth, New Jersey 07033 0539, USA
    Clin Pharmacokinet 41:29-35. 2002
    ..To evaluate the bioavailability, cardiac safety and tolerability of desloratadine when given in combination with the CYP3A4 inhibitor erythromycin...
  8. ncbi request reprint Validation of a sensitive and automated 96-well solid-phase extraction liquid chromatography-tandem mass spectrometry method for the determination of desloratadine and 3-hydroxydesloratadine in human plasma
    Liyu Yang
    Schering Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ 07033 1300, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 792:229-40. 2003
    ..This LC-MS-MS method for the determination of desloratadine and 3-OH desloratadine in human plasma met regulatory requirements for selectivity, sensitivity, goodness of fit, precision, accuracy and stability...
  9. ncbi request reprint Administration of an antagonist of neurokinin receptors 1, 2, and 3 results in reproductive tract changes in beagle dogs, but not rats
    Patricia E Losco
    Schering Plough Research Institute, Lafayette, NJ 07848, USA
    Toxicol Pathol 35:310-22. 2007
    ..In contrast, similar findings were not observed in the reproductive tract of male or female rats, despite overlapping systemic, hypothalamic, and pituitary gland concentrations of SCH 206272...
  10. ncbi request reprint Effects of ezetimibe on cyclosporine pharmacokinetics in healthy subjects
    Arthur J Bergman
    Merck Research Laboratories, West Point, PA 19486, USA
    J Clin Pharmacol 46:321-7. 2006
    ..CyA concentrations should be monitored in patients receiving EZE and CyA...
  11. ncbi request reprint Interaction of single-dose ezetimibe and steady-state cyclosporine in renal transplant patients
    Arthur J Bergman
    Clinical Drug Metabolism, Merck Research Laboratories, WP 75 100, Sumneytown Pike, PO Box 4, West Point, PA 19486, USA
    J Clin Pharmacol 46:328-36. 2006
    ..Because the long-term safety implications of both higher EZE exposures and undetermined effect on CyA are not yet understood, the clinical significance of this interaction is unknown...