R Jubin

Summary

Affiliation: Schering-Plough Research Institute
Country: USA

Publications

  1. ncbi Hepatitis C IRES: translating translation into a therapeutic target
    R Jubin
    Schering Plough Research Institute, Department of Antiviral Therapy, Kenilworth, NJ 07033, USA
    Curr Opin Mol Ther 3:278-87. 2001
  2. ncbi Targeting hepatitis C virus translation: stopping HCV where it starts
    Ronald Jubin
    Schering Plough Research Institute, Department of Antiviral Therapy, 2015 Galloping Hill Road, Mailstop 4945, Kenilworth, NJ 07033, USA
    Curr Opin Investig Drugs 4:162-7. 2003
  3. ncbi Crystal structure of an RNA tertiary domain essential to HCV IRES-mediated translation initiation
    Jeffrey S Kieft
    1 Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06520 8114 USA 2 Howard Hughes Medical Institute, Yale University, New Haven, Connecticut 06520 8114 USA
    Nat Struct Biol 9:370-4. 2002
  4. ncbi Optimizing electroporation conditions for intracellular delivery of morpholino antisense oligonucleotides directed against the hepatitis C virus internal ribosome entry site
    Ronald Jubin
    Department of Antiviral Therapy, Schering Plough Research Institute, Kenilworth, NJ, USA
    Methods Mol Med 106:309-22. 2005

Detail Information

Publications4

  1. ncbi Hepatitis C IRES: translating translation into a therapeutic target
    R Jubin
    Schering Plough Research Institute, Department of Antiviral Therapy, Kenilworth, NJ 07033, USA
    Curr Opin Mol Ther 3:278-87. 2001
    ..These new advances in understanding the mechanism of HCV translation could lead to the development of novel IRES inhibitor strategies...
  2. ncbi Targeting hepatitis C virus translation: stopping HCV where it starts
    Ronald Jubin
    Schering Plough Research Institute, Department of Antiviral Therapy, 2015 Galloping Hill Road, Mailstop 4945, Kenilworth, NJ 07033, USA
    Curr Opin Investig Drugs 4:162-7. 2003
    ..Therefore, screening assays can be developed to identify specific inhibitors of HCV translation as a possible treatment for HCV...
  3. ncbi Crystal structure of an RNA tertiary domain essential to HCV IRES-mediated translation initiation
    Jeffrey S Kieft
    1 Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06520 8114 USA 2 Howard Hughes Medical Institute, Yale University, New Haven, Connecticut 06520 8114 USA
    Nat Struct Biol 9:370-4. 2002
    ..This distorted stack probably serves as an important recognition surface for the translational machinery...
  4. ncbi Optimizing electroporation conditions for intracellular delivery of morpholino antisense oligonucleotides directed against the hepatitis C virus internal ribosome entry site
    Ronald Jubin
    Department of Antiviral Therapy, Schering Plough Research Institute, Kenilworth, NJ, USA
    Methods Mol Med 106:309-22. 2005