C H Jenh

Summary

Affiliation: Schering-Plough Research Institute
Country: USA

Publications

  1. ncbi Cutting edge: species specificity of the CC chemokine 6Ckine signaling through the CXC chemokine receptor CXCR3: human 6Ckine is not a ligand for the human or mouse CXCR3 receptors
    C H Jenh
    Department of Immunology, Schering Plough Research Institute, Kenilworth, NJ 07033, USA
    J Immunol 162:3765-9. 1999
  2. ncbi A highly sensitive and specific assay using a novel human growth hormone cDNA reporter gene regulated by the human interleukin-4 inducible germline epsilon transcript promoter
    C H Jenh
    Department of Immunology, Schering Plough Research Institute, Kenilworth, NJ 07033, USA
    J Immunol Methods 217:87-95. 1998
  3. ncbi Human B cell-attracting chemokine 1 (BCA-1; CXCL13) is an agonist for the human CXCR3 receptor
    C H Jenh
    Department of Immunology, Schering Plough Research Institute, Kenilworth, NJ 07033, USA
    Cytokine 15:113-21. 2001
  4. ncbi Human interferon-inducible 10-kDa protein and human interferon-inducible T cell alpha chemoattractant are allotopic ligands for human CXCR3: differential binding to receptor states
    M A Cox
    Department of Immunology, Schering-Plough Research Institute, Kenilworth, New Jersey 07033, USA
    Mol Pharmacol 59:707-15. 2001
  5. ncbi An inhibitor of CD28-CD80 interactions impairs CD28-mediated costimulation of human CD4 T cells
    J S Fine
    Department of Immunology, Schering Plough Research Institute, Kenilworth, New Jersey, 07033, USA
    Cell Immunol 191:49-59. 1999
  6. ncbi Construction and expression of mouse thymidylate synthase minigenes
    J W DeWille
    Department of Biochemistry, Ohio State University, Columbus 43210
    J Biol Chem 263:84-91. 1988

Collaborators

  • M Zhang
  • M A Cox
  • S K Narula
  • P J Zavodny
  • J S Fine
  • W Gonsiorek
  • J Fine
  • R W Hipkin
  • C C Chou
  • L Justice
  • H D Macosko
  • J W DeWille
  • T Deng
  • L F Johnson
  • C J Harendza

Detail Information

Publications6

  1. ncbi Cutting edge: species specificity of the CC chemokine 6Ckine signaling through the CXC chemokine receptor CXCR3: human 6Ckine is not a ligand for the human or mouse CXCR3 receptors
    C H Jenh
    Department of Immunology, Schering Plough Research Institute, Kenilworth, NJ 07033, USA
    J Immunol 162:3765-9. 1999
    ..In addition, radiolabeled human 6Ckine does not bind to either human CXCR3 or mouse CXCR3. Together these data suggest that human CC chemokine 6Ckine is not a ligand for the human or mouse CXC chemokine receptor CXCR3...
  2. ncbi A highly sensitive and specific assay using a novel human growth hormone cDNA reporter gene regulated by the human interleukin-4 inducible germline epsilon transcript promoter
    C H Jenh
    Department of Immunology, Schering Plough Research Institute, Kenilworth, NJ 07033, USA
    J Immunol Methods 217:87-95. 1998
    ..Y124D inhibits the induction mediated by native hIL-4. These IL-4 inducible cell lines provide a sensitive, specific assay system to study IL-4-regulated gene expression, and in particular the regulation of the germline epsilon promoter...
  3. ncbi Human B cell-attracting chemokine 1 (BCA-1; CXCL13) is an agonist for the human CXCR3 receptor
    C H Jenh
    Department of Immunology, Schering Plough Research Institute, Kenilworth, NJ 07033, USA
    Cytokine 15:113-21. 2001
    ..The biological significance of this new finding is supported by our recent observation that human BCA-1 induces chemotaxis of activated T cells and the BCA-1-induced chemotaxis is inhibited by a monoclonal antibody against human CXCR3...
  4. ncbi Human interferon-inducible 10-kDa protein and human interferon-inducible T cell alpha chemoattractant are allotopic ligands for human CXCR3: differential binding to receptor states
    M A Cox
    Department of Immunology, Schering-Plough Research Institute, Kenilworth, New Jersey 07033, USA
    Mol Pharmacol 59:707-15. 2001
    ..From these data, we conclude that the binding of IP-10 and I-TAC to the R* state of hCXCR3 is allotopic...
  5. ncbi An inhibitor of CD28-CD80 interactions impairs CD28-mediated costimulation of human CD4 T cells
    J S Fine
    Department of Immunology, Schering Plough Research Institute, Kenilworth, New Jersey, 07033, USA
    Cell Immunol 191:49-59. 1999
    ..Moreover, NP1835-2 may serve as a useful probe for investigating the mechanisms involved in T cell nonresponsiveness...
  6. ncbi Construction and expression of mouse thymidylate synthase minigenes
    J W DeWille
    Department of Biochemistry, Ohio State University, Columbus 43210
    J Biol Chem 263:84-91. 1988
    ..Thymidylate synthase enzyme level and mRNA content increased 3-5-fold as cells progressed from G1 through S phase...