John Dulos

Summary

Affiliation: Schering-Plough Research Institute
Country: USA

Publications

  1. pmc Suppression of the inflammatory response in experimental arthritis is mediated via estrogen receptor alpha but not estrogen receptor beta
    John Dulos
    Schering Plough Research Institute, PO Box 20, 5340 BH Oss, The Netherlands
    Arthritis Res Ther 12:R101. 2010
  2. doi Therapeutic antibody targeting of CD97 in experimental arthritis: the role of antigen expression, shedding, and internalization on the pharmacokinetics of anti-CD97 monoclonal antibody 1B2
    Dorien M de Groot
    Schering Plough Research Institute, Oss, The Netherlands
    J Immunol 183:4127-34. 2009

Collaborators

  • Jörg Hamann
  • Dorien M de Groot
  • Annemieke M Boots
  • Karin Stebbins
  • Hans Van Eenennaam
  • Ebo Bos
  • Leonie Teeuwen
  • Gerard Vogel
  • Bronwyn M Owens

Detail Information

Publications2

  1. pmc Suppression of the inflammatory response in experimental arthritis is mediated via estrogen receptor alpha but not estrogen receptor beta
    John Dulos
    Schering Plough Research Institute, PO Box 20, 5340 BH Oss, The Netherlands
    Arthritis Res Ther 12:R101. 2010
    ..Estrogens bind both estrogen receptor (ER)alpha and beta. The contribution of ERalpha and ERbeta to ER-mediated immune modulation was studied in delayed type hypersensitivity (DTH) and in experimental arthritis..
  2. doi Therapeutic antibody targeting of CD97 in experimental arthritis: the role of antigen expression, shedding, and internalization on the pharmacokinetics of anti-CD97 monoclonal antibody 1B2
    Dorien M de Groot
    Schering Plough Research Institute, Oss, The Netherlands
    J Immunol 183:4127-34. 2009
    ..The pharmacokinetic profile of the 1B2 Ab illustrates the complexity of Ab elimination from an organism and stresses the importance of understanding Ag-Ab interactions when developing therapeutic mAbs...