Craig C Correll

Summary

Affiliation: Schering-Plough Research Institute
Country: USA

Publications

  1. pmc TRPV1 antagonists attenuate antigen-provoked cough in ovalbumin sensitized guinea pigs
    Robbie L McLeod
    Peripheral and Pulmonary Neurobiology Schering Plough Research Institute, Kenilworth, NJ 07033 0539, USA
    Cough 2:10. 2006
  2. ncbi request reprint Cloning and pharmacological characterization of mouse TRPV1
    Craig C Correll
    Department of Neurobiology, Schering Plough Research Institute, 2015 Galloping Hill Road, K15 1 1600 Kenilworth, NJ 07033, USA
    Neurosci Lett 370:55-60. 2004
  3. ncbi request reprint Cloning and functional characterization of dog transient receptor potential vanilloid receptor-1 (TRPV1)
    P Tara Phelps
    Neurobiology, Schering Plough Research Institute, Kenilworth, NJ 07033 0539, USA
    Eur J Pharmacol 513:57-66. 2005
  4. ncbi request reprint Characterization of adenosine receptors in the human bladder carcinoma T24 cell line
    P Tara Phelps
    Neurobiology, Schering Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ 07033 0539, USA
    Eur J Pharmacol 536:28-37. 2006
  5. doi request reprint T-type calcium channel blockers: spiro-piperidine azetidines and azetidinones-optimization, design and synthesis
    Elizabeth M Smith
    Department of Medicinal Chemistry, Merck Research Laboratory, Kenilworth, NJ 07033, USA
    Bioorg Med Chem Lett 20:4602-6. 2010
  6. ncbi request reprint Functional TRPV4 channels are expressed in human airway smooth muscle cells
    Yanlin Jia
    Neurobiology, Schering Plough Research Institute, Kenilworth, NJ 07033, USA
    Am J Physiol Lung Cell Mol Physiol 287:L272-8. 2004
  7. ncbi request reprint TRPV1 antagonists as potential antitussive agents
    Robbie L McLeod
    Department of Neurobiology, Schering Plough Research Institute, Kenilworth, NJ 07033 0539, USA
    Lung 186:S59-65. 2008
  8. doi request reprint Spiro-piperidine azetidinones as potent TRPV1 antagonists
    Dong Xiao
    Chemical Research Department, Schering Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ 07033, USA
    Bioorg Med Chem Lett 19:783-7. 2009

Detail Information

Publications8

  1. pmc TRPV1 antagonists attenuate antigen-provoked cough in ovalbumin sensitized guinea pigs
    Robbie L McLeod
    Peripheral and Pulmonary Neurobiology Schering Plough Research Institute, Kenilworth, NJ 07033 0539, USA
    Cough 2:10. 2006
    ..We conclude that TRPV1 channel activation may play role in cough mediated by antigen in sensitized guinea pigs. Our results supports increasing evidence that TRPV1 may play a role in the generation of the cough response...
  2. ncbi request reprint Cloning and pharmacological characterization of mouse TRPV1
    Craig C Correll
    Department of Neurobiology, Schering Plough Research Institute, 2015 Galloping Hill Road, K15 1 1600 Kenilworth, NJ 07033, USA
    Neurosci Lett 370:55-60. 2004
    ....
  3. ncbi request reprint Cloning and functional characterization of dog transient receptor potential vanilloid receptor-1 (TRPV1)
    P Tara Phelps
    Neurobiology, Schering Plough Research Institute, Kenilworth, NJ 07033 0539, USA
    Eur J Pharmacol 513:57-66. 2005
    ..Taken together, these data constitute the first study of the cloning, expression and pharmacological characterization of dog TRPV1...
  4. ncbi request reprint Characterization of adenosine receptors in the human bladder carcinoma T24 cell line
    P Tara Phelps
    Neurobiology, Schering Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ 07033 0539, USA
    Eur J Pharmacol 536:28-37. 2006
    ..Taken together, these data indicate that [Ca2+]i accumulation and cAMP production as well as interleukin-8 secretion is mediated through the adenosine A2B receptor in the T24 cell line...
  5. doi request reprint T-type calcium channel blockers: spiro-piperidine azetidines and azetidinones-optimization, design and synthesis
    Elizabeth M Smith
    Department of Medicinal Chemistry, Merck Research Laboratory, Kenilworth, NJ 07033, USA
    Bioorg Med Chem Lett 20:4602-6. 2010
    ..2) which is a new therapeutic target for the potential treatment of both inflammatory and neuropathic pain. Confirmation and optimization of the potency, selectivity and DMPK properties of leads will be described...
  6. ncbi request reprint Functional TRPV4 channels are expressed in human airway smooth muscle cells
    Yanlin Jia
    Neurobiology, Schering Plough Research Institute, Kenilworth, NJ 07033, USA
    Am J Physiol Lung Cell Mol Physiol 287:L272-8. 2004
    ..We conclude that functional TRPV4 is expressed in human airway smooth muscle cells and may act as an osmolarity sensor in the airway...
  7. ncbi request reprint TRPV1 antagonists as potential antitussive agents
    Robbie L McLeod
    Department of Neurobiology, Schering Plough Research Institute, Kenilworth, NJ 07033 0539, USA
    Lung 186:S59-65. 2008
    ..Current efforts in clinical validation of TRPV1 antagonists revolve around various pain indications; therefore, clinical evaluation of TRPV1 antagonists as antitussive agents will have to await those outcomes...
  8. doi request reprint Spiro-piperidine azetidinones as potent TRPV1 antagonists
    Dong Xiao
    Chemical Research Department, Schering Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ 07033, USA
    Bioorg Med Chem Lett 19:783-7. 2009
    ..An important issue of plasma stability was investigated and resolved. Further focused SAR study lead to the discovery of a potent antagonist with good oral pharmacokinetic profile in rat...