Michael N Alekshun

Summary

Affiliation: Schering-Plough Research Institute
Country: USA

Publications

  1. ncbi Molecular mechanisms of antibacterial multidrug resistance
    Michael N Alekshun
    Schering Plough Research Institute, Kenilworth, NJ 07033, USA
    Cell 128:1037-50. 2007
  2. ncbi New advances in antibiotic development and discovery
    Michael N Alekshun
    Paratek Pharmaceuticals, Inc, 75 Kneeland Street, Boston, MA 02111, USA
    Expert Opin Investig Drugs 14:117-34. 2005
  3. ncbi Novel anti-infection agents: small-molecule inhibitors of bacterial transcription factors
    Todd E Bowser
    Paratek Pharmaceuticals, Inc, 75 Kneeland Street, Boston, MA 02111, USA
    Bioorg Med Chem Lett 17:5652-5. 2007

Detail Information

Publications3

  1. ncbi Molecular mechanisms of antibacterial multidrug resistance
    Michael N Alekshun
    Schering Plough Research Institute, Kenilworth, NJ 07033, USA
    Cell 128:1037-50. 2007
    ..Once established, multidrug-resistant organisms persist and spread worldwide, causing clinical failures in the treatment of infections and public health crises...
  2. ncbi New advances in antibiotic development and discovery
    Michael N Alekshun
    Paratek Pharmaceuticals, Inc, 75 Kneeland Street, Boston, MA 02111, USA
    Expert Opin Investig Drugs 14:117-34. 2005
    ..Many of these antibiotics will be tailored to specific infections caused by a relatively modest number of susceptible and resistant organisms...
  3. ncbi Novel anti-infection agents: small-molecule inhibitors of bacterial transcription factors
    Todd E Bowser
    Paratek Pharmaceuticals, Inc, 75 Kneeland Street, Boston, MA 02111, USA
    Bioorg Med Chem Lett 17:5652-5. 2007
    ..These compounds lack intrinsic antibacterial activity in vitro and were able to limit a bacterial infection in a mouse model of urinary tract infection...