Reena Mehra

Summary

Affiliation: SBM Consulting
Country: USA

Publications

  1. pmc Sleep apnea: a proinflammatory disorder that coaggregates with obesity
    Reena Mehra
    Department of Medicine, Case Comprehensive Cancer Center, Case School of Medicine, Cleveland, OH 44106 6003, USA
    J Allergy Clin Immunol 121:1096-102. 2008
  2. ncbi request reprint Awakening India to obstructive sleep apnoea syndrome
    Reena Mehra
    Pulmonary, Critical Care, Sleep Medicine and Clinical Epidemiology Division, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH 44106, USA
    Indian J Med Res 124:231-4. 2006
  3. ncbi request reprint Soluble interleukin 6 receptor: A novel marker of moderate to severe sleep-related breathing disorder
    Reena Mehra
    Department of Medicine, Case School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Arch Intern Med 166:1725-31. 2006
  4. pmc Interpreting wrist actigraphic indices of sleep in epidemiologic studies of the elderly: the Study of Osteoporotic Fractures
    Reena Mehra
    Department of Medicine and Center of Clinical Investigation, Case School of Medicine, Cleveland, OH 44106 6003, USA
    Sleep 31:1569-76. 2008
  5. ncbi request reprint The association between marijuana smoking and lung cancer: a systematic review
    Reena Mehra
    Department of Medicine, Case Western Reserve University, Cleveland, Ohio 44106 6003, USA
    Arch Intern Med 166:1359-67. 2006
  6. pmc Association of nocturnal arrhythmias with sleep-disordered breathing: The Sleep Heart Health Study
    Reena Mehra
    Department of Medicine and Pediatrics, Case Western Reserve University, Cleveland, OH 44106, USA
    Am J Respir Crit Care Med 173:910-6. 2006
  7. pmc Incidence of serious adverse events during nocturnal polysomnography
    Reena Mehra
    Center for Sleep Disorders Research, Louis Stokes DVA Medical Center, Case Western Reserve University Cleveland, OH, USA
    Sleep 27:1379-83. 2004
  8. pmc Sleep-disordered breathing and urinary albumin excretion in older men
    Muna T Canales
    Department of Medicine, Malcolm Randall Veterans Affairs Medical Center, Gainesville, FL, USA
    Sleep Breath 15:137-44. 2011
  9. pmc Renal function and sleep-disordered breathing in older men
    Muna T Canales
    Department of Medicine, University of Florida, Division of Nephrology, Hypertension and Renal Transplantation, Gainesville, FL 32610, USA
    Nephrol Dial Transplant 23:3908-14. 2008
  10. pmc Sleep duration and biomarkers of inflammation
    Sanjay R Patel
    Division of Pulmonary, Critical Care and Sleep Medicine, University Hospital Case Medical Center and Case Western Reserve University, Cleveland, OH, USA
    Sleep 32:200-4. 2009

Research Grants

Detail Information

Publications28

  1. pmc Sleep apnea: a proinflammatory disorder that coaggregates with obesity
    Reena Mehra
    Department of Medicine, Case Comprehensive Cancer Center, Case School of Medicine, Cleveland, OH 44106 6003, USA
    J Allergy Clin Immunol 121:1096-102. 2008
    ....
  2. ncbi request reprint Awakening India to obstructive sleep apnoea syndrome
    Reena Mehra
    Pulmonary, Critical Care, Sleep Medicine and Clinical Epidemiology Division, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH 44106, USA
    Indian J Med Res 124:231-4. 2006
  3. ncbi request reprint Soluble interleukin 6 receptor: A novel marker of moderate to severe sleep-related breathing disorder
    Reena Mehra
    Department of Medicine, Case School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Arch Intern Med 166:1725-31. 2006
    ..The objectives were to explore the relationship between moderate to severe sleep apnea with IL-6 and sIL-6R levels and to examine morning and evening variability for each cytokine...
  4. pmc Interpreting wrist actigraphic indices of sleep in epidemiologic studies of the elderly: the Study of Osteoporotic Fractures
    Reena Mehra
    Department of Medicine and Center of Clinical Investigation, Case School of Medicine, Cleveland, OH 44106 6003, USA
    Sleep 31:1569-76. 2008
    ..Although wrist actigraphy-derived sleep indices correlate with adverse health outcomes, it is unclear whether these indices identify specific sleep disorders...
  5. ncbi request reprint The association between marijuana smoking and lung cancer: a systematic review
    Reena Mehra
    Department of Medicine, Case Western Reserve University, Cleveland, Ohio 44106 6003, USA
    Arch Intern Med 166:1359-67. 2006
    ..Our objective was to assess the impact of marijuana smoking on the development of premalignant lung changes and lung cancer...
  6. pmc Association of nocturnal arrhythmias with sleep-disordered breathing: The Sleep Heart Health Study
    Reena Mehra
    Department of Medicine and Pediatrics, Case Western Reserve University, Cleveland, OH 44106, USA
    Am J Respir Crit Care Med 173:910-6. 2006
    ..Sleep-disordered breathing recurrent intermittent hypoxia and sympathetic nervous system activity surges provide the milieu for cardiac arrhythmia development...
  7. pmc Incidence of serious adverse events during nocturnal polysomnography
    Reena Mehra
    Center for Sleep Disorders Research, Louis Stokes DVA Medical Center, Case Western Reserve University Cleveland, OH, USA
    Sleep 27:1379-83. 2004
    ..The purpose of the study was to verify whether minimal concern is warranted in regard to serious adverse effects in the sleep laboratory...
  8. pmc Sleep-disordered breathing and urinary albumin excretion in older men
    Muna T Canales
    Department of Medicine, Malcolm Randall Veterans Affairs Medical Center, Gainesville, FL, USA
    Sleep Breath 15:137-44. 2011
    ..Although older men are at increased risk for both kidney disease and SDB, it is unknown whether SDB is associated with higher urinary albumin excretion in this population...
  9. pmc Renal function and sleep-disordered breathing in older men
    Muna T Canales
    Department of Medicine, University of Florida, Division of Nephrology, Hypertension and Renal Transplantation, Gainesville, FL 32610, USA
    Nephrol Dial Transplant 23:3908-14. 2008
    ..Sleep-disordered breathing (SDB) is common in severe chronic kidney disease (CKD) and may contribute to morbidity and mortality in this population. However, the association between mild to moderate CKD and likelihood of SDB is uncertain...
  10. pmc Sleep duration and biomarkers of inflammation
    Sanjay R Patel
    Division of Pulmonary, Critical Care and Sleep Medicine, University Hospital Case Medical Center and Case Western Reserve University, Cleveland, OH, USA
    Sleep 32:200-4. 2009
    ..Extremes of sleep duration have been associated with adverse health outcomes. The mechanism is unclear but may be related to increased inflammation. We sought to assess the association between sleep duration and inflammatory biomarkers...
  11. pmc Association between obstructive sleep apnea severity and endothelial dysfunction in an increased background of cardiovascular burden
    Fadi Seif
    Department of Medicine, Case School of Medicine, Cleveland, OH, USA
    J Sleep Res 22:443-51. 2013
    ..No relation was noted with total sleep time <90 and F-RHI. There was evidence of a graded decline in endothelial function in association with higher levels of intermittent hypoxaemia. ..
  12. pmc Sleep-disordered breathing and prothrombotic biomarkers: cross-sectional results of the Cleveland Family Study
    Reena Mehra
    Department of Medicine, Case Comprehensive Cancer Center, Case School of Medicine, Cleveland, Ohio, USA
    Am J Respir Crit Care Med 182:826-33. 2010
    ..Individuals with sleep-disordered breathing (SDB) are at increased cardiovascular risk, possibly due to SDB-related stresses contributing to atherosclerosis...
  13. ncbi request reprint Sleep apnea in acute coronary syndrome: high prevalence but low impact on 6-month outcome
    Reena Mehra
    Louis Stokes Department of Veterans Affairs Medical Center, Cleveland, OH
    Sleep Med 7:521-8. 2006
    ....
  14. pmc A measure of ventilatory variability at wake-sleep transition predicts sleep apnea severity
    Lamia H Ibrahim
    Department of Medicine, University Hospitals Case Medical Center, 11100 Euclid Ave, Cleveland, OH 44106 6003, USA
    Chest 134:73-8. 2008
    ..We assessed the association of a measure of ventilatory variability measured at the wake-sleep transition with OSA and associated covariates...
  15. pmc Nocturnal Arrhythmias across a spectrum of obstructive and central sleep-disordered breathing in older men: outcomes of sleep disorders in older men (MrOS sleep) study
    Reena Mehra
    Departmentof Medicine, Division of Pulmonary, Case Western Reserve University School of Medicine, Center for Clinical Investigatio, Cleveland, Ohio 44106 6003, USA
    Arch Intern Med 169:1147-55. 2009
    ..We studied the association between sleep-disordered breathing (SDB) with nocturnal atrial fibrillation or flutter (AF) and complex ventricular ectopy (CVE) in older men...
  16. ncbi request reprint Obstructive sleep apnea and diurnal nondipping hemodynamic indices in patients at increased cardiovascular risk
    Fadi Seif
    aDepartment of Medicine, Case School of Medicine, Cleveland, Ohio bBrigham and Women s Hospital cBeth Israel Deaconess Medical Center dVA Boston Healthcare System, Harvard Medical School, Boston, Massachusetts eJohns Hopkins University, Baltimore, Maryland fDepartment of Epidemiology and Biostatistics, Case Western Reserve University gCleveland Clinic, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio, USA
    J Hypertens 32:267-75. 2014
    ..We hypothesized increasing obstructive sleep apnea (OSA) severity would be associated with nondipping blood pressure (BP) in increased cardiovascular disease (CVD) risk...
  17. ncbi request reprint The scoring of respiratory events in sleep: reliability and validity
    Susan Redline
    Department of Pediatrics, Case Western Reserve University, Cleveland, OH, WA 44106 6033, USA
    J Clin Sleep Med 3:169-200. 2007
    ....
  18. pmc Reduced renal function and sleep-disordered breathing in community-dwelling elderly men
    Muna T Canales
    Division of Renal Diseases and Hypertension, Department of Medicine, University of Minnesota, Minneapolis, MN, USA
    Sleep Med 9:637-45. 2008
    ..Sleep-disordered breathing (SDB) may increase the risk of cardiovascular disease (CVD) and death in chronic kidney disease (CKD). However, the association between mild reductions in renal function and SDB is uncertain...
  19. pmc A controlled trial of CPAP therapy on metabolic control in individuals with impaired glucose tolerance and sleep apnea
    Tanya G Weinstock
    Department of Medicine, Brigham and Women s Hospital and Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
    Sleep 35:617-625B. 2012
    ..To address whether treatment of sleep apnea improves glucose tolerance...
  20. pmc Effect of continuous positive airway pressure on an atrial arrhythmia in a patient with mild obstructive sleep apnea
    Harneet Walia
    Department of Family Medicine, University Hospitals Case Medical Center, Cleveland, OH 4410, USA
    J Clin Sleep Med 7:397-8. 2011
    ..This case demonstrates a dose-dependent reduction in atrial ectopy with increasing continuous positive airway pressure (CPAP) in the setting of mild sleep apnea...
  21. pmc Periodic limb movements during sleep and cardiac arrhythmia in older men (MrOS sleep)
    Brian B Koo
    Department of Neurology, Case Western Reserve University School of Medicine, Cleveland, OH
    J Clin Sleep Med 10:7-11. 2014
    ..To determine if periodic limb movements during sleep (PLMS) are associated with nocturnal cardiac arrhythmia...
  22. pmc Left ventricular morphology and systolic function in sleep-disordered breathing: the Sleep Heart Health Study
    Hassan A Chami
    Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
    Circulation 117:2599-607. 2008
    ..We assessed the relation of SDB to LV morphology and systolic function in a community-based sample of middle-aged and older adults...
  23. pmc Variations in physician interpretation of overnight pulse oximetry monitoring
    Rory Ramsey
    Department of Medicine, Case School of Medicine, University Hospitals, 11100 Euclid Ave, Cleveland, OH 44106 6003, USA
    Chest 132:852-9. 2007
    ..The aim of this study was to describe physician interpretation, use, and opinions regarding overnight pulse oximetry...
  24. pmc A man with abnormal sleep behavior
    George P Fahed
    Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University Hospitals Case Medical Center Cleveland, OH 44106 6003, USA
    J Clin Sleep Med 3:533-4. 2007
  25. pmc Fasting glycemia in sleep disordered breathing: lowering the threshold on oxyhemoglobin desaturation
    Katherine Stamatakis
    Johns Hopkins University, Baltimore, MD, USA
    Sleep 31:1018-24. 2008
    ..However, it is not known whether disordered breathing events with oxyhemoglobin desaturation less than 4% are associated with clinical sequelae such as abnormalities in fasting glycemia...
  26. pmc Prevalence and correlates of sleep-disordered breathing in older men: osteoporotic fractures in men sleep study
    Reena Mehra
    San Francisco Coordinating Center, University of California San Francisco at San Diego, USA
    J Am Geriatr Soc 55:1356-64. 2007
    ..To determine the prevalence and distribution of sleep-disordered breathing and associated correlates in a large cohort of older men using several standardized definitions...
  27. ncbi request reprint A 52-year-old man with excessive daytime sleepiness
    Bipin D Sarodia
    Department of Pulmonary and Critical Care Medicine, The Cleveland Clinic, Cleveland Clinic Foundaton, OH 44195, USA
    Cleve Clin J Med 69:193, 199-202, 207-8. 2002
  28. pmc Effects of marijuana smoking on pulmonary function and respiratory complications: a systematic review
    Jeanette M Tetrault
    Clinical Epidemiology Research Center, Department of Veterans Affairs Connecticut Healthcare System, West Haven Veterans Affairs Medical Center, 950 Campbell Avenue, West Haven, CT 06516, USA
    Arch Intern Med 167:221-8. 2007
    ....

Research Grants2

  1. Oxidative Stress in Sleep Apnea and Cardiac Disease
    Reena Mehra; Fiscal Year: 2007
    ..The proposal will provide a key training opportunity to foster my development as an independent clinical epidemiologist with commitment to patient-based research in sleep medicine and cardiopulmonary disease. ..