A J Saxon

Summary

Country: USA

Publications

  1. doi request reprint Quetiapine for the treatment of cocaine dependence: an open-label trial
    Annette Kennedy
    Mental Illness Research, Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA
    J Clin Psychopharmacol 28:221-4. 2008
  2. ncbi request reprint Challenges in the adoption of new pharmacotherapeutics for addiction to alcohol and other drugs
    Andrew J Saxon
    Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98108, USA
    Pharmacol Ther 108:119-28. 2005
  3. ncbi request reprint Transporting efficacious treatments from academia to community: barriers and opportunities
    Andrew J Saxon
    Department of Psychiatry and Behavioral Sciences, Center of Excellence in Substance Abuse Treatment and Education, University of Washington, VA Puget Sound Health Care System, 1660 South Columbian Way, Seattle 98108 1595, USA
    Drug Alcohol Depend 70:127-9. 2003
  4. ncbi request reprint Genetic determinants of addiction to opioids and cocaine
    Andrew J Saxon
    Department of Psychiatry, University of Washington School of Medicine Center of Excellence in Substance Abuse Treatment and Education, VA Puget Sound Health Care System, Seattle, WA 98108, USA
    Harv Rev Psychiatry 13:218-32. 2005
  5. ncbi request reprint Randomized trial of onsite versus referral primary medical care for veterans in addictions treatment
    Andrew J Saxon
    VA Puget Sound Health Care System, Seattle, Washington 98108, USA
    Med Care 44:334-42. 2006
  6. ncbi request reprint Trauma, symptoms of posttraumatic stress disorder, and associated problems among incarcerated veterans
    A J Saxon
    Center of Excellence in Substance Abuse Treatment and Education in Seatle, USA
    Psychiatr Serv 52:959-64. 2001
  7. ncbi request reprint Further validation of the alcohol dependence scale as an index of severity
    Andrew J Saxon
    Department of Psychiatry and Behavioral Sciences, University of Washington, 1959 NE Pacific Street, Seattle, Washington 98195, USA
    J Stud Alcohol Drugs 68:149-56. 2007
  8. ncbi request reprint Smoking cessation treatment among dually diagnosed individuals: preliminary evaluation of different pharmacotherapies
    Andrew J Saxon
    VA Puget Sound Health Care System, University of Washington, Seattle, WA 98108, USA
    Nicotine Tob Res 5:589-96. 2003
  9. pmc Methadone medical maintenance in primary care. An implementation evaluation
    Joseph O Merrill
    Department of Medicine, University of Washington, Seattle, WA, USA
    J Gen Intern Med 20:344-9. 2005
  10. ncbi request reprint Detecting bipolar disorder among treatment-seeking substance abusers
    K L Sloan
    VA Puget Sound Health Care System Seattle Division, Washington 98108, USA
    Am J Drug Alcohol Abuse 26:13-23. 2000

Detail Information

Publications35

  1. doi request reprint Quetiapine for the treatment of cocaine dependence: an open-label trial
    Annette Kennedy
    Mental Illness Research, Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA
    J Clin Psychopharmacol 28:221-4. 2008
    ..Additional research is needed to confirm the current findings and to further delineate the role quetiapine may play in the treatment of cocaine use disorders...
  2. ncbi request reprint Challenges in the adoption of new pharmacotherapeutics for addiction to alcohol and other drugs
    Andrew J Saxon
    Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98108, USA
    Pharmacol Ther 108:119-28. 2005
    ..The paper concludes with a discussion of barriers and ways to surmount the barriers and to foster greater use of medications in alcohol and drug treatment...
  3. ncbi request reprint Transporting efficacious treatments from academia to community: barriers and opportunities
    Andrew J Saxon
    Department of Psychiatry and Behavioral Sciences, Center of Excellence in Substance Abuse Treatment and Education, University of Washington, VA Puget Sound Health Care System, 1660 South Columbian Way, Seattle 98108 1595, USA
    Drug Alcohol Depend 70:127-9. 2003
  4. ncbi request reprint Genetic determinants of addiction to opioids and cocaine
    Andrew J Saxon
    Department of Psychiatry, University of Washington School of Medicine Center of Excellence in Substance Abuse Treatment and Education, VA Puget Sound Health Care System, Seattle, WA 98108, USA
    Harv Rev Psychiatry 13:218-32. 2005
    ..In this article some of the recent scientific evidence for genetic determinants of opioid and cocaine dependence is reviewed...
  5. ncbi request reprint Randomized trial of onsite versus referral primary medical care for veterans in addictions treatment
    Andrew J Saxon
    VA Puget Sound Health Care System, Seattle, Washington 98108, USA
    Med Care 44:334-42. 2006
    ..Providing primary care within addictions clinics (onsite care) may improve medical and SUD treatment outcomes in this population...
  6. ncbi request reprint Trauma, symptoms of posttraumatic stress disorder, and associated problems among incarcerated veterans
    A J Saxon
    Center of Excellence in Substance Abuse Treatment and Education in Seatle, USA
    Psychiatr Serv 52:959-64. 2001
    ..To help improve treatment for incarcerated veterans, the study examined exposure to trauma, symptoms of posttraumatic stress disorder (PTSD), functional status, and treatment history in a group of incarcerated veterans...
  7. ncbi request reprint Further validation of the alcohol dependence scale as an index of severity
    Andrew J Saxon
    Department of Psychiatry and Behavioral Sciences, University of Washington, 1959 NE Pacific Street, Seattle, Washington 98195, USA
    J Stud Alcohol Drugs 68:149-56. 2007
    ....
  8. ncbi request reprint Smoking cessation treatment among dually diagnosed individuals: preliminary evaluation of different pharmacotherapies
    Andrew J Saxon
    VA Puget Sound Health Care System, University of Washington, Seattle, WA 98108, USA
    Nicotine Tob Res 5:589-96. 2003
    ..Additional research is needed to assess medication effects in randomized trials, to explore effects of more intensive treatments, and to assess possible harm reduction from smoking interventions within this population...
  9. pmc Methadone medical maintenance in primary care. An implementation evaluation
    Joseph O Merrill
    Department of Medicine, University of Washington, Seattle, WA, USA
    J Gen Intern Med 20:344-9. 2005
    ..Methadone is effective treatment for opioid addiction, but regulations restrict its use. Methadone medical maintenance treats stabilized methadone patients in a medical setting, but only experimental programs have been studied...
  10. ncbi request reprint Detecting bipolar disorder among treatment-seeking substance abusers
    K L Sloan
    VA Puget Sound Health Care System Seattle Division, Washington 98108, USA
    Am J Drug Alcohol Abuse 26:13-23. 2000
    ..Further work using structured interview as the diagnostic criterion is under way to validate this instrument...
  11. ncbi request reprint An open trial of transdermal nicotine replacement therapy for smoking cessation among alcohol- and drug-dependent inpatients
    A J Saxon
    VA Puget Sound Health Care System, Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, USA
    J Subst Abuse Treat 14:333-7. 1997
    ....
  12. doi request reprint The association of persistent pain with out-patient addiction treatment outcomes and service utilization
    Ryan M Caldeiro
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA 98195 6560, USA
    Addiction 103:1996-2005. 2008
    ..To estimate the prevalence of persistent pain among veterans in out-patient addiction treatment and examine associated addiction treatment outcomes and medical and psychiatric service use...
  13. ncbi request reprint Slow tapering from methadone maintenance in a program encouraging indefinite maintenance
    Donald A Calsyn
    Department of Veterans Affairs, Puget Sound Health Care System, Seattle, WA 98108, USA
    J Subst Abuse Treat 30:159-63. 2006
    ..For a few patients, a taper to a lower methadone dose and a switch to buprenorphine/naloxone are obtainable. Program policies that support both tapering attempts and indefinite maintenance are described in this article...
  14. pmc Evaluation of a minimal services treatment track for noncompliant patients in opioid substitution treatment
    Donald A Calsyn
    Addictions Treatment Center, Veterans Affairs Puget Sound Health Care System and the University of Washington School of Medicine, Seattle, 98108, USA
    Am J Public Health 93:1086-8. 2003
  15. doi request reprint A pilot trial of the alpha-1 adrenergic antagonist, prazosin, for alcohol dependence
    Tracy L Simpson
    Center of Excellence in Substance Abuse Treatment and Education, University of Washington, Seattle, WA 98108, USA
    Alcohol Clin Exp Res 33:255-63. 2009
    ..Theory and preclinical evidence suggest that noradrenergic circuits may be involved in alcohol reinforcement and relapse. We therefore tested the alpha-1 adrenergic receptor antagonist, prazosin, as a pharmacotherapy for AD...
  16. ncbi request reprint Post-traumatic stress disorder and smoking: a systematic review
    Steven S Fu
    Center for Chronic Disease Outcomes Research, Veterans Affairs Medical Center, and Department of Medicine, University of Minnesota, Minneapolis, MN, USA
    Nicotine Tob Res 9:1071-84. 2007
    ..Intervention studies that test behavioral and pharmacological interventions designed specifically for use in patients with PTSD are needed to reduce morbidity and mortality in this population...
  17. ncbi request reprint Implementation of buprenorphine in the Veterans Health Administration: results of the first 3 years
    Adam J Gordon
    VISN 4 Mental Illness, Research, Education, and Clinical Center, Center for Health Equity Research and Promotion, VA Pittsburgh Healthcare System, Mailcode 151 C, University Drive C, Pittsburgh, PA 15240, United States
    Drug Alcohol Depend 90:292-6. 2007
    ....
  18. ncbi request reprint Integrating smoking cessation into mental health care for post-traumatic stress disorder
    Miles McFall
    Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA
    Clin Trials 4:178-89. 2007
    ..Post-traumatic stress disorder (PTSD) is associated with a high prevalence of smoking, heavy cigarette consumption and low cessation rates...
  19. ncbi request reprint Integrating tobacco cessation treatment into mental health care for patients with posttraumatic stress disorder
    Miles McFall
    Northwest Network Mental Illness Research, Education and Clinical Center, Seattle, Washington, USA
    Am J Addict 15:336-44. 2006
    ..The number of IC sessions and a previous quit history greater than six months predicted RPPA. Stopping smoking was not associated with worsening PTSD or depression...
  20. doi request reprint Integrating tobacco cessation into mental health care for posttraumatic stress disorder: a randomized controlled trial
    Miles McFall
    Veterans Affairs Puget Sound Health Care System, 1660 S Columbian Way, S 116 MHC, Seattle, WA 98108, USA
    JAMA 304:2485-93. 2010
    ..Most smokers with mental illness do not receive tobacco cessation treatment...
  21. ncbi request reprint Women in addictions treatment: comparing VA and community samples
    Tania M Davis
    Center of Excellence in Substance Abuse Treatment and Education, VA Puget Sound Health Care System, Seattle Division S116ATC, 1660 S Columbian Way, Seattle, WA 98108, USA
    J Subst Abuse Treat 23:41-8. 2002
    ..The differences between and similarities among the two treatment groups have implications for design of women-specific SUD treatment programs...
  22. ncbi request reprint The Addiction Severity Index medical and psychiatric composite scores measure similar domains as the SF-36 in substance-dependent veterans: concurrent and discriminant validity
    Donald A Calsyn
    VA Puget Sound Health Care System, Center of Excellence in Substance Abuse Treatment and Education, 1660 S Columbian Way, Seattle, WA 98108, USA
    Drug Alcohol Depend 76:165-71. 2004
    ..This study examines the concurrent validity of these ASI composite scores in relation to the short form 36-item health survey (SF-36), a well-established measure of health-related quality of life/functional health status...
  23. ncbi request reprint The Alcohol Use Disorders Identification Test (AUDIT) predicts alcohol withdrawal symptoms during inpatient detoxification
    Joseph P Reoux
    Veterans Affairs Puget Sound Health Care System, Addictions Treatment Center, Seattle, WA 98108, USA
    J Addict Dis 21:81-91. 2002
    ..The AUDIT should be explored alone and in combination with other parameters to improve screening for clinically meaningful AWS in other settings...
  24. ncbi request reprint Pharmacists' and technicians' perceptions and attitudes toward dispensing buprenorphine/ naloxone to patients with opioid dependence
    Dennis W Raisch
    Veterans Affairs Cooperative Studies Program, Clinical Research Pharmacy Coordinating Center, Albuquerque, NM 87106, USA
    J Am Pharm Assoc (2003) 45:23-32. 2005
    ..To assess the perceptions and attitudes of pharmacists and pharmacy technicians involved in an office-based opioid dependence treatment program using buprenorphine/naloxone...
  25. ncbi request reprint Brief motivational feedback improves post-incarceration treatment contact among veterans with substance use disorders
    Tania M Davis
    Center of Excellence in Substance Abuse Treatment and Education, VA Puget Sound Health Care System, Seattle, WA 98108, USA
    Drug Alcohol Depend 69:197-203. 2003
    ..To test the efficacy of providing brief motivational feedback to increase post-incarceration substance use disorders (SUD) treatment contact...
  26. ncbi request reprint Improving the rates of quitting smoking for veterans with posttraumatic stress disorder
    Miles McFall
    PTSD Programs S 116 MHC, VA Puget Sound Health Care System, 1660 S Columbian Way, Seattle, WA 98108, USA
    Am J Psychiatry 162:1311-9. 2005
    ..This study aimed to improve the rate of quitting smoking for veterans with PTSD by integrating treatment for nicotine dependence into mental health care...
  27. ncbi request reprint Disulfiram use in patients with abnormal liver function test results
    A J Saxon
    Addictions Treatment Center, Department of Psychiatry and Behavioral Sciences, VA Puget Sound Health Care System, University of Washington, Seattle, USA
    J Clin Psychiatry 59:313-6. 1998
    ..This study examines the effects of disulfiram in alcohol-dependent patients with elevated liver function test results and/or serologic evidence of hepatitis C virus (HCV) infection...
  28. ncbi request reprint An open-label pilot study of risperidone in the treatment of methamphetamine dependence
    Charles W Meredith
    Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA
    J Psychoactive Drugs 39:167-72. 2007
    ..0 (SD = 8.4) to 51.8 (SD = 8.3; t = 2.7, p <.05), and positive symptom distress declined from a mean of 52.8 (SD =8.0) to 41.7 (SD = 8.6; t= 3.0, p <.05). Risperidone was well tolerated and associated with decreased MA use...
  29. ncbi request reprint A comparison of methamphetamine-dependent inpatients childhood attention deficit hyperactivity disorder symptomatology
    Craig Jaffe
    Department of Psychiatry and Behavioral Sciences, University of Washington, 12013 Pinehurst Way NE, Seattle, WA 98125, USA
    J Addict Dis 24:133-52. 2005
    ..All participants demonstrated significant reductions in psychiatric symptoms with abstinence. Methamphetamine-dependent individuals with ADHD symptoms are common and pose a significant treatment challenge...
  30. ncbi request reprint A double-blind, double-dummy, randomized, prospective pilot study of the partial mu opiate agonist, buprenorphine, for acute detoxification from heroin
    Michael R Oreskovich
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, and Veterans Affairs Puget Sound Healthcare System, 1660 South Columbian Way, Seattle, WA 98108, USA
    Drug Alcohol Depend 77:71-9. 2005
    ..There were no discontinuations due to treatment-related adverse events. Both HD and LD regimens are safe and efficacious treatment for opioid detoxification, but HD demonstrated superiority to C on a greater number of measures...
  31. pmc Study results from the Clinical Trials Network's first 10 years: where do they lead?
    Elizabeth A Wells
    School of Social Work, University of Washington, Seattle, WA 98105, USA
    J Subst Abuse Treat 38:S14-30. 2010
    ..The CTN provides a unique opportunity to systematically design trials that incorporate treatment improvements from previous trials and to direct efforts toward innovations most likely to be incorporated into practice...
  32. doi request reprint Associations of housing status with substance abuse treatment and service use outcomes among veterans
    Jonathan R Buchholz
    U S Department of Veterans Affairs VA Puget Sound Health Care System, Seattle, Washington 98108, USA
    Psychiatr Serv 61:698-706. 2010
    ....
  33. ncbi request reprint Divalproex sodium in alcohol withdrawal: a randomized double-blind placebo-controlled clinical trial
    J P Reoux
    Veterans Affairs Puget Sound Health Care System and Department of Psychiatry, University of Washington School of Medicine, Seattle, Washington 98108, USA
    Alcohol Clin Exp Res 25:1324-9. 2001
    ..This study reports on a randomized, double-blind, placebo-controlled trial of divalproex sodium in acute alcohol withdrawal...
  34. ncbi request reprint Single dose of 24 milligrams of buprenorphine for heroin detoxification: an open-label study of five inpatients
    Kathleen Ang-Lee
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington 98195 6560, USA
    J Psychoactive Drugs 38:505-12. 2006
    ..Use of ancillary medications was minimal. This study suggests that a single high dose of buprenorphine can be used safely and effectively for inpatient detoxification...
  35. ncbi request reprint Implications of chronic methamphetamine use: a literature review
    Charles W Meredith
    Department of Psychiatry and Behavioral Sciences, University of Washington, and VA Puget Sound Health Care System S 116 ATC, 1160 S Columbian Way, Seattle, WA 98108, USA
    Harv Rev Psychiatry 13:141-54. 2005
    ..Atypical antipsychotics may have some promise in this regard...