Ruth Santacreu

Summary

Country: USA

Publications

  1. ncbi request reprint Sustained high plasma plasminogen activator inhibitor-1 levels are associated with severity and mortality in septic patients
    Leonardo Lorente
    Intensive Care Unit, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain Electronic address
    Thromb Res 134:182-6. 2014
  2. pmc Association between serum tissue inhibitor of matrix metalloproteinase-1 levels and mortality in patients with severe brain trauma injury
    Leonardo Lorente
    Intensive Care Unit, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain
    PLoS ONE 9:e94370. 2014
  3. pmc Association of sepsis-related mortality with early increase of TIMP-1/MMP-9 ratio
    Leonardo Lorente
    Intensive Care Unit, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain
    PLoS ONE 9:e94318. 2014
  4. pmc Severe septic patients with mitochondrial DNA haplogroup JT show higher survival rates: a prospective, multicenter, observational study
    Leonardo Lorente
    Intensive Care Unit, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain
    PLoS ONE 8:e73320. 2013
  5. doi request reprint Chlorhexidine-silver sulfadiazine-impregnated venous catheters save costs
    Leonardo Lorente
    Department of Critical Care, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain Electronic address
    Am J Infect Control 42:321-4. 2014
  6. ncbi request reprint Lesser incidence of accidental catheter removal with femoral versus radial arterial access
    L Lorente
    Department of Intensive Care, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain
    Med Intensiva 37:316-9. 2013
  7. pmc Prognostic value of malondialdehyde serum levels in severe sepsis: a multicenter study
    Leonardo Lorente
    Intensive Care Unit, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain
    PLoS ONE 8:e53741. 2013
  8. ncbi request reprint Ventilator-associated pneumonia with or without toothbrushing: a randomized controlled trial
    L Lorente
    Department of Critical Care, Hospital Universitario de Canarias, Ofra s n La Cuesta, La Laguna, 38320 Santa Cruz de Tenerife, Spain
    Eur J Clin Microbiol Infect Dis 31:2621-9. 2012
  9. doi request reprint Rifampicin-miconazole-impregnated catheters save cost in jugular venous sites with tracheostomy
    L Lorente
    Department of Critical Care, Hospital Universitario de Canarias, Ofra s n La Cuesta, La Laguna, 38320, Santa Cruz de Tenerife, Spain
    Eur J Clin Microbiol Infect Dis 31:1833-6. 2012
  10. pmc Survival and mitochondrial function in septic patients according to mitochondrial DNA haplogroup
    Leonardo Lorente
    Intensive Care Unit, Hospital Universitario de Canarias, La Laguna 38320, Santa Cruz de Tenerife, Spain
    Crit Care 16:R10. 2012

Collaborators

  • Maria Lecuona
  • Jose Blanquer
  • Jose A Paramo
  • Josune Orbe
  • M J Ramos
  • Nerea Varo
  • Nicolás Serrano
  • J Rello
  • Jose R Perez
  • C Garcia
  • J Valles
  • Alberto Dominguez-Rodriguez
  • M Martin
  • J Martinez
  • A Rodriguez
  • M A Rodriguez
  • Stijn I Blot
  • Leonardo Lorente
  • Alejandro Jimenez
  • Maria L Mora
  • L Lorente
  • Jordi Sole-Violan
  • A Jimenez
  • M L Mora
  • César Díaz
  • Lorenzo Labarta
  • Antonio Sierra
  • José Ferreres
  • Juan M Borreguero-León
  • Jose A Rodriguez
  • Juan José Jiménez
  • José Luis Iribarren
  • Jose L Iribarren
  • Juan J Jimenez
  • Juan María Borreguero-León
  • I Roca
  • Esther López-Gallardo
  • Julio Montoya
  • Ruth Iceta
  • Eduardo Ruiz-Pesini
  • Santiago Lubillo
  • José M Ferrer-Agüero
  • Maria C Llimiñana
  • Ramón Galván
  • N Lafuente
  • E Pastor
  • A Sierra
  • S Palmero
  • M T Brouard
  • C Naranjo
  • J J Jimenez
  • Felipe Belmonte
  • J Castedo
  • R Galvan
  • Ysamar Barrios
  • Ibrahim Nassar
  • Maitane Brouard
  • Rosalia Perez
  • Juan J Jimenez Rivera
  • Melitón Santana
  • Rafael Martinez
  • Juan Castedo
  • Oswaldo Gonzalez
  • Judith Cabrera
  • Patricia Lopez
  • Mónica Argüeso
  • Juan J Cáceres
  • Jorge Solera
  • Luis Ramos
  • Lorena Raja
  • Raquel Ortiz
  • Agustín González
  • Pedro Abreu-Gonzalez
  • Armando Morera-Fumero
  • Eduardo Pastor
  • Noelia Lafuente
  • Manuel Sánchez-Palacios
  • Eduardo Gómez-Melini
  • Froilán Méndez
  • Miriram Hernández
  • Nuria Medina
  • María T Brouard
  • J L Iribarren
  • Juan C Medina
  • Manuel Sanchez
  • C Leon
  • Jose M Rodriguez
  • Antonio Milena
  • Jose M Raya
  • Maribel Diaz

Detail Information

Publications52

  1. ncbi request reprint Sustained high plasma plasminogen activator inhibitor-1 levels are associated with severity and mortality in septic patients
    Leonardo Lorente
    Intensive Care Unit, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain Electronic address
    Thromb Res 134:182-6. 2014
    ..However, some questions remain unanswered, such as whether there is an association between plasma PAI-1 levels and sepsis severity and mortality, and inflammation state during the first week...
  2. pmc Association between serum tissue inhibitor of matrix metalloproteinase-1 levels and mortality in patients with severe brain trauma injury
    Leonardo Lorente
    Intensive Care Unit, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain
    PLoS ONE 9:e94370. 2014
    ..Thus, the aim of this study was to determine whether serum TIMP-1 and MMP-9 levels are associated with mortality in patients with severe TBI...
  3. pmc Association of sepsis-related mortality with early increase of TIMP-1/MMP-9 ratio
    Leonardo Lorente
    Intensive Care Unit, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain
    PLoS ONE 9:e94318. 2014
    ....
  4. pmc Severe septic patients with mitochondrial DNA haplogroup JT show higher survival rates: a prospective, multicenter, observational study
    Leonardo Lorente
    Intensive Care Unit, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain
    PLoS ONE 8:e73320. 2013
    ....
  5. doi request reprint Chlorhexidine-silver sulfadiazine-impregnated venous catheters save costs
    Leonardo Lorente
    Department of Critical Care, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain Electronic address
    Am J Infect Control 42:321-4. 2014
    ..However, in these analyses, the CVC-related cost included the increase of hospital stay...
  6. ncbi request reprint Lesser incidence of accidental catheter removal with femoral versus radial arterial access
    L Lorente
    Department of Intensive Care, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain
    Med Intensiva 37:316-9. 2013
    ..Few data are available on accidental arterial catheter removal, and no studies have been found comparing the incidence of ACR between different arterial catheter sites...
  7. pmc Prognostic value of malondialdehyde serum levels in severe sepsis: a multicenter study
    Leonardo Lorente
    Intensive Care Unit, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain
    PLoS ONE 8:e53741. 2013
    ..We wished to determine whether malondialdehyde (MDA) serum levels were associated with severity and 30-day mortality in a large series of patients with sepsis...
  8. ncbi request reprint Ventilator-associated pneumonia with or without toothbrushing: a randomized controlled trial
    L Lorente
    Department of Critical Care, Hospital Universitario de Canarias, Ofra s n La Cuesta, La Laguna, 38320 Santa Cruz de Tenerife, Spain
    Eur J Clin Microbiol Infect Dis 31:2621-9. 2012
    ..87, 95 % confidence interval [CI] = 0.469-1.615; p = 0.75). Adding manual toothbrushing to chlorhexidine oral care does not help to prevent VAP in critical care patients on mechanical ventilation...
  9. doi request reprint Rifampicin-miconazole-impregnated catheters save cost in jugular venous sites with tracheostomy
    L Lorente
    Department of Critical Care, Hospital Universitario de Canarias, Ofra s n La Cuesta, La Laguna, 38320, Santa Cruz de Tenerife, Spain
    Eur J Clin Microbiol Infect Dis 31:1833-6. 2012
    ..The results of our study may contribute to clinical decision-making and selection of those patients who could benefit from the use of antimicrobial-impregnated catheters...
  10. pmc Survival and mitochondrial function in septic patients according to mitochondrial DNA haplogroup
    Leonardo Lorente
    Intensive Care Unit, Hospital Universitario de Canarias, La Laguna 38320, Santa Cruz de Tenerife, Spain
    Crit Care 16:R10. 2012
    ..Given that COX catalytic subunits are encoded by mtDNA, the objective of the present study was to explore whether mtDNA population genetic variation could affect COX activity and quantity and favors sepsis survival...
  11. doi request reprint Lower catheter-related bloodstream infection in arterial than in venous femoral catheter
    L Lorente
    Department of Intensive Care, Hospital Universitario de Canarias, 38320, La Laguna, Tenerife
    Eur J Clin Microbiol Infect Dis 31:487-90. 2012
    ..The novel finding of our study is that the risk of CRBSI was higher in venous than in arterial femoral catheters. Thus, special approaches to prevent CRBSI might play a more important role in venous than in arterial catheters...
  12. pmc Factors associated with excessive bleeding in cardiopulmonary bypass patients: a nested case-control study
    Juan J Jimenez Rivera
    Intensive Care Unit, University Hospital of Canary Islands, La Laguna, Spain
    J Cardiothorac Surg 2:17. 2007
    ..Less than 50% of patients undergoing re-intervention exhibit surgical sources of bleeding. We studied clinical and genetic factors associated with EB...
  13. pmc Tranexamic acid attenuates inflammatory response in cardiopulmonary bypass surgery through blockade of fibrinolysis: a case control study followed by a randomized double-blind controlled trial
    Juan J Jimenez
    Intensive Care Department, Hospital Universitario de Canarias, Ofra s n La Cuesta, La Laguna, 38320, Spain
    Crit Care 11:R117. 2007
    ..Tranexamic acid (TA) reduces fibrinolysis and blood loss after cardiopulmonary bypass (CPB). However, its effects on IR and vasoplegic shock (VS) are not well known and elucidating these effects was the main objective of this study...
  14. doi request reprint Influence of tracheostomy on the incidence of central venous catheter-related bacteremia
    L Lorente
    Intensive Care Unit, Hospital Universitario de Canarias, Ofra s n La Cuesta, La Laguna, 38320 Santa Cruz de Tenerife, Spain
    Eur J Clin Microbiol Infect Dis 28:1141-5. 2009
    ..001). Besides, we found a higher incidence of CRB in patients with tracheostomy using the jugular access compared to subclavian access (21.64 vs. 5.11 per 1,000 catheter-days; OR = 4.23; 95% CI = 1.44-infinite; P = 0.0097)...
  15. pmc Matrix metalloproteinase-9, -10, and tissue inhibitor of matrix metalloproteinases-1 blood levels as biomarkers of severity and mortality in sepsis
    Leonardo Lorente
    Intensive Care Unit, Hospital Universitario de Canarias, Ofra, 38320 Santa Cruz de Tenerife, Spain
    Crit Care 13:R158. 2009
    ..The objective of this study was to determine the predictive value of MMP-9, MMP-10, and TIMP-1 on clinical severity and mortality in a large series of patients with severe sepsis...
  16. doi request reprint Higher arterial catheter-related infection rates in femoral than in dorsalis pedis access
    L Lorente
    Department of Intensive Care, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain
    J Hosp Infect 74:365-9. 2010
    ..6; 95% confidence interval: 1.37-infinite; P=0.01). These results suggest that dorsalis pedis arterial access should be used in preference to femoral arterial access in order to reduce the risk of ACRI...
  17. doi request reprint [Femoral venous catheterization. Does it really need to be avoided?]
    L Lorente
    Unidad de Cuidados Intensivos, Hospital Universitario de Canarias, La Laguna, Tenerife, Espana
    Med Intensiva 33:442-9. 2009
    ..a decrease in the incidence of CVCBSI, but an increase in the rate of mechanical complications as pneumothorax and/or hemothorax? 2) Couldn't antimicrobial-impregnated CVCs be used to prevent CVCBSI when the femoral venous access is used?..
  18. doi request reprint Lower arterial catheter-related infection in brachial than in femoral access
    Leonardo Lorente
    Department of Intensive Care, Hospital Universitario de Canarias, Ofra s n, La Laguna, Santa Cruz de Tenerife, Spain
    Am J Infect Control 38:e40-2. 2010
    ..08 vs 0 per 1000 catheter-days, respectively; odds ratio, 6.18; 95% confidence interval: 1.11-infinite; P = .02). Thus, arterial brachial access should be used in preference to femoral access...
  19. doi request reprint Platelet cytochrome c oxidase activity and quantity in septic patients
    Leonardo Lorente
    Intensive Care Unit, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain
    Crit Care Med 39:1289-94. 2011
    ..The objective was to evaluate the relationship between cytochrome c oxidase activities and quantities and 6-month survival in a larger series of septic patients using a less invasive method (circulating platelets)...
  20. ncbi request reprint Influence of tracheostomy on the incidence of catheter-related bloodstream infection in the catheterization of jugular vein by posterior access
    L Lorente
    Intensive Care Unit, Hospital Universitario de Canarias, Ofra s n La Cuesta, La Laguna, 38320 Santa Cruz de Tenerife, Spain
    Eur J Clin Microbiol Infect Dis 30:1049-51. 2011
    ..24 vs 0 episodes of CRBSI per 1,000 catheter-day; odds ratio = 23.92; 95% CI = 1.86-infinite; p = 0.008). Thus, the presence of tracheostomy is a risk factor of CRBSI on the catheterization of jugular vein by posterior access...
  21. pmc Association between serum soluble CD40 ligand levels and mortality in patients with severe sepsis
    Leonardo Lorente
    Intensive Care Unit, Hospital Universitario de Canarias, Ofra, S N, La Laguna 38320, Santa Cruz de Tenerife, Spain
    Crit Care 15:R97. 2011
    ..Thus, the aim of this study was to determine whether circulating sCD40L levels could be a marker of adverse outcome in a large cohort of patients with severe sepsis...
  22. doi request reprint Lower incidence of catheter-related bloodstream infection in cubital than in femoral artery access
    Leonardo Lorente
    Department of Intensive Care, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain
    Scand J Infect Dis 43:814-7. 2011
    ..However the development of randomized controlled trials is necessary before this conclusion can be definitively established. In addition, it is necessary to consider other potential mechanical complications when decision-making...
  23. doi request reprint Clinical cure of ventilator-associated pneumonia treated with piperacillin/tazobactam administered by continuous or intermittent infusion
    Leonardo Lorente
    Intensive Care Unit, Hospital Universitario de Canarias, Ofra s n, La Cuesta, La Laguna 38320, Tenerife, Spain
    Int J Antimicrob Agents 33:464-8. 2009
    ....
  24. ncbi request reprint The management of acute lower respiratory tract infection
    L Lorente
    Department of Critical Care, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain
    Minerva Med 99:459-81. 2008
    ....
  25. ncbi request reprint Internal jugular venous catheter-related bacteremia according to central and posterior accesses
    Leonardo Lorente
    Hospital Universitario de Canarias, Intensive Care Unit, Ofra s n, La Cuesta, La Laguna, 38320 Santa Cruz de Tenerife, Spain
    Intensive Care Med 33:1071-5. 2007
    ..Although there are many studies about central venous catheter-related infection, we have not found any analysis of the incidence of internal jugular venous catheter-related bacteremia associated with different accesses...
  26. pmc Central venous catheter-related infection in a prospective and observational study of 2,595 catheters
    Leonardo Lorente
    Department of Intensive Care, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain
    Crit Care 9:R631-5. 2005
    ..The objective of this study was to analyze the incidence of catheter-related local infection (CRLI) and catheter-related bloodstream infection (CRBSI) with central venous catheters (CVCs) according to different access sites...
  27. pmc Ventilator-associated pneumonia using a heated humidifier or a heat and moisture exchanger: a randomized controlled trial [ISRCTN88724583]
    Leonardo Lorente
    Intensive Care Unit, Hospital Universitario de Canarias, La Laguna, Tenerife, Spain
    Crit Care 10:R116. 2006
    ..The aim of this study was to determine the incidence of VAP associated with HHs or HMEs...
  28. pmc Arterial catheter-related infection of 2,949 catheters
    Leonardo Lorente
    Department of Intensive Care, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain
    Crit Care 10:R83. 2006
    ..The objective of the present study was to analyze the incidence of catheter-related local infection (CRLI) and catheter-related bloodstream infection (CRBSI) of arterial catheters according to different access sites...
  29. ncbi request reprint Tracheal suction by closed system without daily change versus open system
    Leonardo Lorente
    Department of Critical Care, Hospital Universitario de Canarias, Ofra s n, La Cuesta, La Laguna, 38320, Santa Cruz de Tenerife, Spain
    Intensive Care Med 32:538-44. 2006
    ..However, is it necessary to change the closed system daily?..
  30. ncbi request reprint Meropenem by continuous versus intermittent infusion in ventilator-associated pneumonia due to gram-negative bacilli
    Leonardo Lorente
    Intensive Care Unit, Hospital Universitario de Canarias, Tenerife, Spain
    Ann Pharmacother 40:219-23. 2006
    ..However, limited data exist on the clinical efficacy of meropenem administered by continuous infusion...
  31. pmc Accidental catheter removal in critically ill patients: a prospective and observational study
    Leonardo Lorente
    Staff Intensivist, Department of Intensive Care, Hospital Universitario de Canarias, Tenerife, Spain
    Crit Care 8:R229-33. 2004
    ..The objective of the present study was to analyze the incidence of ACR for all types of catheters in the ICU...
  32. ncbi request reprint Catheter-related infection in critically ill patients
    Leonardo Lorente
    Department of Intensive Care, Hospital Universitario de Canarias, Ofra s n La Cuesta, 38320 La Laguna, Santa Cruz de Tenerife, Spain
    Intensive Care Med 30:1681-4. 2004
    ..To describe the incidence of the catheter-related local infection (CRLI) and catheter-related bloodstream infection (CRBSI) of central venous catheters (CVCs) and arterial catheters (ACs)...
  33. ncbi request reprint Microorganisms responsible for intravascular catheter-related bloodstream infection according to the catheter site
    Leonardo Lorente
    Department of Intensive Care and Research Unit, Hospital Universitario de Canarias, Tenerife, Spain
    Crit Care Med 35:2424-7. 2007
    ..We therefore compared the proportion of IVC-RBSI due to Gram-negative bacteria and yeasts according to catheter site...
  34. ncbi request reprint Influence of an endotracheal tube with polyurethane cuff and subglottic secretion drainage on pneumonia
    Leonardo Lorente
    Department of Critical Care, Hospital Universitario de Canarias, Ofra s n, La Cuesta, La Laguna 38320, Santa Cruz de Tenerife, Spain
    Am J Respir Crit Care Med 176:1079-83. 2007
    ....
  35. doi request reprint The use of rifampicin-miconazole-impregnated catheters reduces the incidence of femoral and jugular catheter-related bacteremia
    Leonardo Lorente
    Department of Critical Care, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain
    Clin Infect Dis 47:1171-5. 2008
    ..In previous studies, we have found a higher incidence of central venous catheter-related bacteremia among patients with femoral and central jugular accesses than among patients with other venous accesses...
  36. doi request reprint Catheter-related bacteremia from femoral and central internal jugular venous access
    L Lorente
    Intensive Care Unit, Hospital Universitario de Canarias, Ofra s n La Cuesta, La Laguna, Santa Cruz de Tenerife, Spain
    Eur J Clin Microbiol Infect Dis 27:867-71. 2008
    ..93; 95% confidence interval: 1.03-3.73; P = 0.04). Central internal jugular venous access could be considered a safer route of venous access than femoral access in minimizing the risk of central venous catheter-related bacteremia...
  37. ncbi request reprint Comparison of clinical cure rates in adults with ventilator-associated pneumonia treated with intravenous ceftazidime administered by continuous or intermittent infusion: a retrospective, nonrandomized, open-label, historical chart review
    Leonardo Lorente
    Intensive Care Unit, Hospital Universitario de Canarias Ofra s n, La Cuesta, La Laguna 38320, Tenerife, Spain
    Clin Ther 29:2433-9. 2007
    ..Beta-lactam antibiotics are reported to exhibit time-dependent bactericidal activity. However, there are limited data on the clinical efficacy of ceftazidime administered by continuous infusion...
  38. ncbi request reprint Evidence on measures for the prevention of ventilator-associated pneumonia
    L Lorente
    Intensive Care Unit, Hospital Universitario de Canarias, C Ofra s n, La Laguna, Tenerife, 38320, Spain
    Eur Respir J 30:1193-207. 2007
    ..The present review article is useful for identifying evidence-based processes that can be modified to improve patients' safety...
  39. doi request reprint Lower associated costs using rifampicin-miconazole‒impregnated catheters compared with standard catheters
    Leonardo Lorente
    Department of Critical Care, Hospital of the University of Canarias, Santa Cruz de Tenerife, Spain
    Am J Infect Control 39:895-7. 2011
    ..001). Our data indicate that the use of rifampicin-miconazole-impregnated catheters can save associated costs...
  40. ncbi request reprint Ventilator-associated pneumonia using a closed versus an open tracheal suction system
    Leonardo Lorente
    Department of Critical Care, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain
    Crit Care Med 33:115-9. 2005
    ..The aim of this study was to analyze the prevalence of ventilator-associated pneumonia (VAP) using a closed-tracheal suction system vs. an open system...
  41. doi request reprint Lower incidence of catheter-related bloodstream infection in subclavian venous access in the presence of tracheostomy than in femoral venous access: prospective observational study
    L Lorente
    Intensive Care Unit Research Unit of the Hospital Universitario de Canarias, Tenerife, Spain
    Clin Microbiol Infect 17:870-2. 2011
    ..In this study, we found lower CRBSI in subclavian venous access in the presence of tracheostomy than in femoral venous access (3.9 vs. 10.1 CRBSI per 1000 catheter-days; odds ratio = 0.39; 95% confidence interval ≤0.001-0.91; p 0.03)...
  42. ncbi request reprint Bacterial filters in respiratory circuits: an unnecessary cost?
    Leonardo Lorente
    Department of Critical Care, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain
    Crit Care Med 31:2126-30. 2003
    ..To evaluate the efficacy of bacterial filters (BF) to decrease pneumonia associated with mechanical ventilation (MV)...
  43. ncbi request reprint Periodically changing ventilator circuits is not necessary to prevent ventilator-associated pneumonia when a heat and moisture exchanger is used
    Leonardo Lorente
    Department of Critical Care, Hospital Universitario de Canarias, La Laguna, Spain
    Infect Control Hosp Epidemiol 25:1077-82. 2004
    ..The Centers for Disease Control and Prevention recommended not changing the circuits periodically...
  44. ncbi request reprint Prolonged intubation rates after coronary artery bypass surgery and ICU risk stratification score
    Nicolás Serrano
    Hospital Universitario de Canarias, Critical Care Department, Universidad de La Laguna, 38320 La Laguna, Tenerife, Spain
    Chest 128:595-601. 2005
    ..To determine prolonged intubation rates among patients undergoing coronary artery bypass graft (CABG) surgery, and to evaluate the ability of the Intensive Care Unit Risk Stratification Score (ICURSS) model to predict these events...
  45. doi request reprint [Pandemic influenza A in the ICU: experience in Spain and Latin America. GETGAG/SEMICYUC/(Spanish Working Group on Severe Pandemic Influenza A/SEMICYUC)]
    A Rodriguez
    Unidad de Cuidados Intensivos, Hospital Joan XXIII, CIBER Enfermedades Respiratorias, IISPV, Tarragona, Espana
    Med Intensiva 34:87-94. 2010
    ..It has spread very rapidly since the first cases were diagnosed in Mexico with the subsequent spread of the virus throughout the Southern Cone and Europe during the summer season...
  46. doi request reprint New issues and controversies in the prevention of ventilator-associated pneumonia
    Leonardo Lorente
    Intensive Care Unit, Hospital Universitario de Canarias, La Laguna, Tenerife, Spain
    Am J Respir Crit Care Med 182:870-6. 2010
    ..More research is necessary to clarify the role of continuous cuff pressure monitoring, removal of biofilm formation in the endotracheal tubes, and routine saline instillation before tracheal suctioning...
  47. doi request reprint Microorganisms responsible for femoral catheter-related bloodstream infection
    Leonardo Lorente
    Crit Care Med 36:657-8. 2008
  48. ncbi request reprint The micro-organism responsible for central venous catheter related bloodstream infection depends on catheter site
    Leonardo Lorente
    Intensive Care Med 32:1449-50. 2006
  49. ncbi request reprint The catheter site influences in the micro-organism responsible of arterial catheter-related infection
    Leonardo Lorente
    Intensive Care Med 32:1919-20. 2006
  50. ncbi request reprint Equivalence of posterior internal jugular and subclavian accesses in the incidence of central venous catheter related bacteremia
    Leonardo Lorente
    Intensive Care Med 33:2230-1. 2007