Research Topics
| E P RileySummaryAffiliation: San Diego State University Country: USA Publications
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Publications
Fetal alcohol effects: mechanisms and treatmentE P Riley
Center for Behavioral Teratology EPR, JDT, Department of Psychology, San Diego State University, San Diego, California 92120, USA
Alcohol Clin Exp Res 25:110S-116S. 2001..Hungund; and (4) Fetal alcohol exposure alters the wiring of serotonin system at mid-gestation, by F. Zhou, Y. Sari, Charles Goodlett, T. Powrozek, and Ting-Kai Li...- Teratogenic effects of alcohol: a decade of brain imagingEdward P Riley
Center for Behavioral Teratology, San Diego State University, 6363 Alvarado Court 209, San Diego, CA 92120, USA
Am J Med Genet C Semin Med Genet 127:35-41. 2004.... - Neurobehavioral consequences of prenatal alcohol exposure: an international perspectiveEdward P Riley
San Diego, State University, San Diego, California 92120, USA
Alcohol Clin Exp Res 27:362-73. 2003..Mattson, E. P. Riley, A. Matveeva, and G. Marintcheva; and (6) Long-term follow-up of Finnish children exposed to alcohol in utero in various durations, by Marit I. Korkman and I. Autti-Rämö. The discussant was Ting-Kai Li... - Fetal alcohol spectrum disorders: an overviewEdward P Riley
Department of Psychology, Center for Behavioral Teratology, San Diego State University, San Diego, CA 92120, USA
Neuropsychol Rev 21:73-80. 2011..A diagnostic goal is to recognize FAS as a disorder of brain rather than one of physical characteristics... - Prenatal alcohol exposure: advancing knowledge through international collaborationsEdward P Riley
Center for Behavioral Teratology, San Diego State University, California 92120, USA
Alcohol Clin Exp Res 27:118-35. 2003..International collaborations provide a wealth of resources for the study of FAS, and it was hoped that this meeting might better enhance the work ongoing in this area, and provide opportunities for future work... - Fetal alcohol spectrum disorders: an overview with emphasis on changes in brain and behaviorEdward P Riley
Department of Psychology and Center for Behavioral Teratology, 6363 Alvarado Court, 209, San Diego State University, California 92120, USA
Exp Biol Med (Maywood) 230:357-65. 2005..As evidenced by the staggering financial impact these disorders have on society, prevention efforts need to be aimed at high-risk groups, and this issue needs to be made a high priority in terms of public health... - MK-801 can exacerbate or attenuate behavioral alterations associated with neonatal alcohol exposure in the rat, depending on the timing of administrationJ D Thomas
Department of Psychology, Center for Behavioral Teratology, San Diego State University, San Diego, California 92120, USA
Alcohol Clin Exp Res 25:764-73. 2001..In the present study, we altered the timing of MK-801 delivery in relation to the last alcohol dose to determine if its protective effects were specific to the ethanol withdrawal phase... - Neuropsychological comparison of alcohol-exposed children with or without physical features of fetal alcohol syndromeS N Mattson
Department of Psychology, San Diego State University, California 92120, USA
Neuropsychology 12:146-53. 1998..These data suggest that heavy prenatal alcohol exposure is related to a consistent pattern of neuropsychological deficits and the degree of these deficits may be independent of the presence of physical features associated with FAS... - Executive functioning in children with heavy prenatal alcohol exposureS N Mattson
Center for Behavioral Teratology, San Diego State University, California, USA
Alcohol Clin Exp Res 23:1808-15. 1999..Until recently, comprehensive measures of EF have not been available within one test battery. This study used a battery of tests to assess four domains of EF in alcohol-exposed children... - Collaborative initiative on fetal alcohol spectrum disorders: methodology of clinical projectsSarah N Mattson
Center for Behavioral Teratology, San Diego State University, San Diego, CA 92120, USA
Alcohol 44:635-41. 2010..This article describes the methodology being used by the clinical projects that pertain to assessment of children and adolescents. Domains being addressed are dysmorphology, neurobehavior, 3-D facial imaging, and brain imaging... - Neonatal choline supplementation ameliorates the effects of prenatal alcohol exposure on a discrimination learning task in ratsJ D Thomas
Center for Behavioral Teratology, San Diego State University, Suite 209, 6363 Alvarado Ct, San Diego, CA 92120, USA
Neurotoxicol Teratol 22:703-11. 2000..These data suggest that early dietary interventions may reduce the severity of fetal alcohol effects... - Differential vulnerability to motor deficits in second replicate HAS and LAS rats following neonatal alcohol exposureJ D Thomas
Center for Behavioral Teratology, Department of Psychology, San Diego State University, 6363 Alvarado Ct Suite 209, San Diego, CA 92120, USA
Pharmacol Biochem Behav 75:17-24. 2003..They also provide evidence that genetic factors play a role in fetal alcohol effects and suggest that phenotypic markers may indicate individuals at high risk for some fetal alcohol effects... - Parent ratings of behavior in children with heavy prenatal alcohol exposure and IQ-matched controlsS N Mattson
Center for Behavioral Teratology, San Diego State University, California, USA
Alcohol Clin Exp Res 24:226-31. 2000..However, the degree to which these disturbances are related to factors other than alcohol, such as general intellectual functioning or socioeconomic status, is not known... - Implicit and explicit memory functioning in children with heavy prenatal alcohol exposureS N Mattson
Center for Behavioral Teratology, San Diego State University, CA, USA
J Int Neuropsychol Soc 5:462-71. 1999..These results further characterize the memory deficits in children with heavy prenatal alcohol exposure suggesting that in spite of learning and memory deficits, they are able to benefit from priming of verbal information... - Administration of eliprodil during ethanol withdrawal in the neonatal rat attenuates ethanol-induced learning deficitsJ D Thomas
Center for Behavioral Teratology, Department of Psychology, San Diego State University, 6363 Alvarado Ct, Ste 209, San Diego, CA 92120, USA
Psychopharmacology (Berl) 175:189-95. 2004..Eliprodil is a more selective NMDA receptor antagonist that acts at the polyamine modulatory site of NMDA receptors... - Alcohol consumption among low-income pregnant LatinasChristina D Chambers
Department of Pediatrics and Family and Preventive Medicine, University of California, San Diego, La Jolla, CA, USA
Alcohol Clin Exp Res 29:2022-8. 2005..Selective interventions in low-income Latinas are warranted, and should be focused on women of reproductive age who are binge or frequent drinkers and who are at risk of becoming pregnant... - Verbal and nonverbal fluency in children with heavy prenatal alcohol exposureA M Schonfeld
Center for Behavioral Teratology, San Diego State University, California, USA
J Stud Alcohol 62:239-46. 2001.... - Administration of low doses of MK-801 during ethanol withdrawal in the developing rat pup attenuates alcohol's teratogenic effectsJennifer D Thomas
Center for Behavioral Teratology, Department of Psychology, San Diego State University, 6363 Alvarado Court, Suite 209, San Diego, CA 92120, USA
Alcohol Clin Exp Res 26:1307-13. 2002..This study examined the dose dependency of MK-801's ability to mitigate ethanol's teratogenic effects... - Teratogenic effects of alcohol on brain and behaviorS N Mattson
Center for Behavioral Teratology, San Diego State University (SDSU, San Diego, California, USA
Alcohol Res Health 25:185-91. 2001..Functional brain imaging studies also have detected changes in alcohol-exposed children indicative of deficits in information processing and memory tasks... - Social information processing skills in children with histories of heavy prenatal alcohol exposureChristie L McGee
Center for Behavioral Teratology, Department of Psychology, San Diego State University, 6363 Alvarado Ct Suite 200, San Diego, CA 92120, USA
J Abnorm Child Psychol 37:817-30. 2009..Such difficulties may lead to problems in social functioning and warrant early intervention... - Motor response selection in children with fetal alcohol spectrum disordersRoger W Simmons
Motor Control Laboratory, Department of Exercise and Nutritional Sciences, San Diego State University, San Diego, CA 92182, USA
Neurotoxicol Teratol 28:278-85. 2006..It was concluded that FASD adolescents require additional time to process increasing amount of information, but that the time required for motor response selection is not delayed relative to control group performance... - Prenatal alcohol exposure affects frontal-striatal BOLD response during inhibitory controlSusanna L Fryer
Joint Doctoral Program in Clinical Psychology, San Diego State University, University of California, San Diego, California, USA
Alcohol Clin Exp Res 31:1415-24. 2007..This study characterized the neural substrates underlying the disinhibited behavioral profile of individuals with fetal alcohol spectrum disorders (FASD)... - Differences in executive functioning in children with heavy prenatal alcohol exposure or attention-deficit/hyperactivity disorderLinnea Vaurio
Department of Psychology, Center for Behavioral Teratology, San Diego State University, San Diego, California, USA
J Int Neuropsychol Soc 14:119-29. 2008..These results, which indicate that, although EF deficits occurred in both clinical groups, the degree and pattern of deficit differed between the ALC and ADHD groups, may improve differential diagnosis... - Motor response programming and movement time in children with heavy prenatal alcohol exposureRoger W Simmons
San Diego State University, CA 92182, USA
Alcohol 44:371-8. 2010..The observed results indicate children with FAS experience deficits in response programming and movement time production... - Central and peripheral timing variability in children with heavy prenatal alcohol exposureRoger W Simmons
Motor Control Laboratory, School of Exercise and Nutritional Sciences, San Diego State University, San Diego, California 92182, USA
Alcohol Clin Exp Res 33:400-7. 2009.... - Deficits in social problem solving in adolescents with prenatal exposure to alcoholChristie L McGee
Joint Doctoral Program in Clinical Psychology, San Diego State University University of California, San Diego, California, USA
Am J Drug Alcohol Abuse 34:423-31. 2008..Such impairments are likely to have a significant impact on social and academic functioning and reflect their need for critical services otherwise unavailable to them... - Inconsistent report of pre-pregnancy-recognition alcohol use by LatinasSuzanne C Hughes
Center for Behavioral Epidemiology and Community Health, San Diego State University, 9245 Sky Park Court, Suite 230, San Diego, CA 92123, USA
Matern Child Health J 13:857-64. 2009..This study compared pregnant Latinas' report of alcohol use for the 3-month period before pregnancy recognition with two different methods of data collection, in an attempt to identify opportunities for improved screening... - Interhemispheric transfer in children with heavy prenatal alcohol exposureTresa M Roebuck
Center for Bahavioral Teratology, San Diego State University, Caliornia 92120, USA
Alcohol Clin Exp Res 26:1863-71. 2002..Such deficits in interhemispheric transfer are likely to be related to the myriad of other behavioral and cognitive impairments observed in these children... - Fractionated simple and choice reaction time in children with prenatal exposure to alcoholRoger W Simmons
Motor Control Laboratory, Department of Exercise and Nutritional Sciences, San Diego State University, San Diego, California 92182, USA
Alcohol Clin Exp Res 26:1412-9. 2002..Each RT interval was fractionated into premotor and motor components to assess the central processing of stimulus information and peripheral motor unit recruitment, respectively... - Neurodevelopmental follow-up of children of women infected with varicella during pregnancy: a prospective studySarah N Mattson
Center for Behavioral Teratology, Department of Psychology, San Diego State University, 6363 Alvarado Court, Suite 209, San Diego, CA 92120, USA
Pediatr Infect Dis J 22:819-23. 2003..However, the incidence of neurobehavioral deficits in asymptomatic structurally normal children whose mothers had clinically diagnosed varicella-zoster virus infection is unknown... - Children with heavy prenatal alcohol exposure demonstrate deficits on multiple measures of concept formationChristie L McGee
Center for Behavioral Teratology, Department of Psychology, San Diego State University, San Diego, California 92120, USA
Alcohol Clin Exp Res 32:1388-97. 2008..Children with heavy prenatal alcohol exposure have documented impairments in executive functioning (EF). One component of EF, concept formation, has not been well studied in this group... - Classifying children with heavy prenatal alcohol exposure using measures of attentionKara T Lee
Center for Behavioral Teratology, Department of Psychology, San Diego State University, San Diego, California 92120, USA
J Int Neuropsychol Soc 10:271-7. 2004..These data indicate that children with heavy prenatal alcohol exposure can be distinguished from non-exposed controls with a high degree of accuracy using 2 commonly used measures of attention... - Characterization of white matter microstructure in fetal alcohol spectrum disordersSusanna L Fryer
San Diego Joint Doctoral Program in Clinical Psychology, San Diego State University University of California, San Diego, California, USA
Alcohol Clin Exp Res 33:514-21. 2009..Exposure to alcohol during gestation is associated with CNS alterations, cognitive deficits, and behavior problems. This study investigated microstructural aspects of putative white matter abnormalities following prenatal alcohol exposure... - Moral maturity and delinquency after prenatal alcohol exposureAmy M Schonfeld
Center for Behavioral Teratology, San Diego State University, San Diego, California, USA
J Stud Alcohol 66:545-54. 2005..Although delinquent populations and those with intellectual and behavioral deficits exhibit impaired moral judgment and reasoning, this area remains unexplored in alcohol-exposed individuals... - Insulin-like growth factor-I mitigates motor coordination deficits associated with neonatal alcohol exposure in ratsNancy N H McGough
Department of Psychology, San Diego State University, San Diego, CA 92120, USA
Neurotoxicol Teratol 31:40-8. 2009..These data indicate that IGF-I may be a potential treatment for some of ethanol's damaging effects, a finding that has important implications for children of women who drink alcohol during pregnancy... - BOLD response during spatial working memory in youth with heavy prenatal alcohol exposureAndrea D Spadoni
San Diego State University University of California San Diego, CA 92120, USA
Alcohol Clin Exp Res 33:2067-76. 2009..Structural brain abnormalities observed in regions supporting spatial working memory (SWM) may contribute to observed deficits in visuospatial functioning in youth with fetal alcohol spectrum disorders (FASDs)... - Alcohol use in pregnancy: inadequate recommendations for an increasing problemK L Jones
Division of Dysmorphology and Teratology, Department of Pediatrics, University of California, San Diego, La Jolla, CA 92037-0811, USA
BJOG 113:967-8. 2006 - Impaired language performance in young children with heavy prenatal alcohol exposureChristie L McGee
Center for Behavioral Teratology, San Diego State University, Department of Psychology, San Diego, CA 92120, USA
Neurotoxicol Teratol 31:71-5. 2009..However, these deficits are likely to impact the social interactions and behavioral adjustment of children with prenatal alcohol exposure... - Cingulate gyrus morphology in children and adolescents with fetal alcohol spectrum disordersOlivia A Bjorkquist
Center for Behavioral Teratology, Department of Psychology, San Diego State University, San Diego, CA, USA
Psychiatry Res 181:101-7. 2010..The observed volumetric reductions in the cingulate gyrus may contribute to the disruptive and emotionally dysregulated behavioral profile commonly observed in this population... - Brain imaging and fetal alcohol spectrum disordersChristie L McGee
Joint Doctoral Program in Clinical Psychology, San Diego State University, San Diego, CA, USA
Ann Ist Super Sanita 42:46-52. 2006..This review demonstrates that specific areas of the brain may be more vulnerable to prenatal exposure to alcohol... - Alterations in circadian rhythm phase shifting ability in rats following ethanol exposure during the third trimester brain growth spurtHiromi Sakata-Haga
Department of Psychology, Center for Behavioral Teratology, San Diego State University, San Diego, California 92120, USA
Alcohol Clin Exp Res 30:899-907. 2006..Disruptions in circadian regulation may cause abnormal behavioral rhythmicity, such as disrupted sleep and feeding patterns, as seen in individuals prenatally exposed to ethanol... - Comparison of adaptive behavior in children with heavy prenatal alcohol exposure or attention-deficit/hyperactivity disorderNicole Crocker
Department of Psychology, San Diego State University, San Diego, CA, USA
Alcohol Clin Exp Res 33:2015-23. 2009..Therefore, the aim of the current study was to compare adaptive behavior in children with histories of heavy prenatal alcohol exposure (ALC), nonexposed children with ADHD (ADHD), and typically developing controls (CON)... - Neuroimaging and fetal alcohol spectrum disordersAndria L Norman
Center for Behavioral Teratology, Department of Psychology, San Diego State University, San Diego, California, USA
Dev Disabil Res Rev 15:209-17. 2009..Continued neuroimaging studies are needed to further advance understanding of the neuroteratogenic effects of alcohol... - Neuroimaging and fetal alcohol spectrum disordersAndrea D Spadoni
Joint Doctoral Program in Clinical Psychology, San Diego State University University of California, San Diego, CA, USA
Neurosci Biobehav Rev 31:239-45. 2007.... - Timing accuracy and variability in children with prenatal exposure to alcoholTara S Wass
Department of Child and Family Studies, University of Tennessee, Knoxville 37996, USA
Alcohol Clin Exp Res 26:1887-96. 2002..The present study examined performance on two types of timing tasks to determine the extent to which prenatal alcohol exposure affects perception, movement planning, and movement execution during tasks that require temporal processing... - Mapping cerebellar vermal morphology and cognitive correlates in prenatal alcohol exposureEric Kan
Laboratory of Neuro Imaging, Department of Neurology, University of California, Los Angeles, California, USA
Neuroreport 16:1285-90. 2005..These observations expand on previous reports of cerebellar abnormalities in prenatal alcohol exposure, in that they localize the specific pattern of cerebellar vermal dysmorphology... - Evaluation of psychopathological conditions in children with heavy prenatal alcohol exposureSusanna L Fryer
San Diego State University University of California San Diego Joint Doctoral Program in Clinical Psychology, USA
Pediatrics 119:e733-41. 2007.... - Brain metabolic alterations in adolescents and young adults with fetal alcohol spectrum disordersAse Fagerlund
Folkhalsan Research Center, Helsinki, Finland
Alcohol Clin Exp Res 30:2097-104. 2006..This study examined brain metabolism using magnetic resonance spectroscopy (MRS) and searched for regions of specific vulnerability in adolescents and young adults prenatally exposed to alcohol... - Bimanual coordination in alcohol-exposed children: role of the corpus callosumTresa M Roebuck-Spencer
National Rehabilitation Hospital, Washington, DC 20010, USA
J Int Neuropsychol Soc 10:536-48. 2004..However, as task complexity and reliance on interhemispheric interaction increases, children with FASD demonstrate variable and inaccurate performance... - Regional brain shape abnormalities persist into adolescence after heavy prenatal alcohol exposureElizabeth R Sowell
Laboratory of Neuro Imaging, Department of Neurology, University of California Los Angeles, 710 Westwood Plaza, Room 4 238, Los Angeles, CA 90095 1769, USA
Cereb Cortex 12:856-65. 2002.... - Neurophysiologic consequences of neonatal ethanol exposure in the ratCraig J Slawecki
The Scripps Research Institute, Department of Neuropharmacology, CVN 14, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
Alcohol 34:187-96. 2004..This neurobehavioral profile in the rat is consistent with clinical observations of attention deficits and hyperactivity in children exposed to ethanol during prenatal development... - MRI and muscle signal intensities in alcoholics compared with control subjectsMarco Bigliocchi
Department of Radiology, Alcohol Liver Unit, University of Rome La Sapienza, Rome, Italy
Alcohol Clin Exp Res 28:1875-80. 2004..This technique could be included among other diagnostic tools for alcoholic myopathy with further improvements and if the signal alterations can be corroborated by biopsy evidence... - Memory and perseveration on a win-stay, lose-shift task in rats exposed neonatally to alcoholMatthew C Bell
Psychology Department, Santa Clara University, 500 El Camino Real, Santa Clara, California 95053, USA
J Stud Alcohol 67:851-60. 2006..The present study was designed to examine the relationship between perseveration and memory... - Accuracy of the diagnosis of physical features of fetal alcohol syndrome by pediatricians after specialized trainingKenneth Lyons Jones
Department of Pediatrics, Division of Dysmorphology and Teratology, University of California San Diego, La Jolla, California, USA
Pediatrics 118:e1734-8. 2006..After a structured training program for pediatricians, we examined the ability to accurately diagnose fetal alcohol syndrome... - Mapping cortical gray matter asymmetry patterns in adolescents with heavy prenatal alcohol exposureElizabeth R Sowell
Laboratory of Neuro Imaging, Department of Neurology, University of California at Los Angeles, 90095, USA
Neuroimage 17:1807-19. 2002.... - Abnormal cortical thickness and brain-behavior correlation patterns in individuals with heavy prenatal alcohol exposureElizabeth R Sowell
Laboratory of Neuro Imaging, Department of Neurology, University of California, Los Angeles, CA 90095 7334, USA
Cereb Cortex 18:136-44. 2008..Further, the significant interactions show for the first time that brain-behavior relationships are altered as a function of heavy prenatal alcohol exposure... - National Task Force on Fetal Alcohol Syndrome and Fetal Alcohol Effect: defining the national agenda for fetal alcohol syndrome and other prenatal alcohol-related effectsMary Kate Weber
Division of Birth Defects and Developmental Disabilities, National Center on Birth Defects and Developmental Disabilities, USA
MMWR Recomm Rep 51:9-12. 2002..An explanation of how the Task Force recommendations were generated and the Task Forces next steps are also reported...
Research Grants
- Behavioral and MRI Evaluation of Prenatal Alcohol ExposureEdward P Riley; Fiscal Year: 2010..far, and that this multidisciplinary project will expand our understanding of the devastating effects of prenatal alcohol exposure, hopefully informing us sufficiently that we might begin to propose reasonable intervention strategies ..
- BEHAVIORAL EFFECTS OF NEONATAL ALCOHOL EXPOSUREEdward Riley; Fiscal Year: 2007..These studies, if successful, will provide additional support for withdrawal as one mechanism of ethanol's teratogenicity and provide data regarding a possible treatment to mitigate some of the teratogenic effects of alcohol. ..
- Pilot Project Core - CIFASDEdward Riley; Fiscal Year: 2005..In this regard, a project was chosen with a potential of diagnosing FASD early in life, based upon ultrasound imaging of the corpus callos. ..
- A Cross-Cultural Assessment of FASD (U24 Core)Edward Riley; Fiscal Year: 2005..The purpose of this consortium is to provide the answers to much needed questions as it relates to the full spectrum of consequences resulting from prenatal alcohol. ..
- Neurobehavior Core for CIFASD (U24)Edward Riley; Fiscal Year: 2005..6) To interact with the Dysmorphology, Brain Imaging, 3D Facial Imaging, and Informatics Cores to determine the relationships between the various measures. ..
- BEHAVIORAL, EEG, AND MRI EVALUATION OF PRENATAL ALCOHOLEdward Riley; Fiscal Year: 2004..We believe that our approach has been successful thus far, and that this multidisciplinary project will expand our understanding of the devastating effects of prenatal alcohol exposure, perhaps leading to new treatment strategies. ..
- 12th World Congress on Biomedical Alcohol ResearchEdward Riley; Fiscal Year: 2004..Partial coverage of publication costs of the Congress proceedings is also requested. ..
- Alcohol Research in the Science/Practitioner ModelEdward Riley; Fiscal Year: 2007..Their training has provided them with the scientific rigor necessary to be successful academic researchers and the clinical skills to ask applicable and relevant questions regarding alcohol abuse and alcoholism. ..
- BEHAVIORAL EFFECTS OF NEONATAL ALCOHOL EXPOSUREEdward P Riley; Fiscal Year: 2010..abstract_text> ..
- Behavioral and MRI Evaluation of Prenatal Alcohol ExposureEdward Riley; Fiscal Year: 2009..far, and that this multidisciplinary project will expand our understanding of the devastating effects of prenatal alcohol exposure, hopefully informing us sufficiently that we might begin to propose reasonable intervention strategies ..
- Administrative Core of the CIFASD (U24)Edward Riley; Fiscal Year: 2007..In conjunction with the Steering Committees, it will establish annual priorities and deal with issues related to allocation of resources. 5. Administer the Developmental Projects of the CIFASD. ..
- 13th World Congress on Biomedical Alcohol ResearchEdward Riley; Fiscal Year: 2006..Partial coverage of publication costs of the Congress program, abstract book and proceedings is also requested. The 13th World Congress of ISBRA will be held September 10-13, 2006. ..
- BEHAVIORAL EFFECTS OF NEONATAL ALCOHOL EXPOSUREEdward Riley; Fiscal Year: 1999....
- BEHAVIORAL EFFECTS OF NEONATAL ALCOHOL EXPOSUREEdward Riley; Fiscal Year: 1993....
- BEHAVIORAL EFFECTS OF NEONATAL ALCOHOL EXPOSUREEdward Riley; Fiscal Year: 2003..abstract_text> ..