L J Willmore

Summary

Affiliation: Saint Louis University
Country: USA

Publications

  1. doi request reprint Posttraumatic epilepsy: hemorrhage, free radicals and the molecular regulation of glutamate
    L J Willmore
    Department of Neurology and Psychiatry, Saint Louis University School of Medicine, 1402 South Grand Blvd, St Louis, MI 63104, USA
    Neurochem Res 34:688-97. 2009
  2. doi request reprint Monitoring and antiepileptic drug safety
    L James Willmore
    Saint Louis University School of Medicine, 1402 South Grand Boulevard C 130, St Louis, MO 63104 1004, USA
    Continuum (Minneap Minn) 19:801-5. 2013
  3. ncbi request reprint Divalproex and epilepsy
    L James Willmore
    Saint Louis University School of Medicine, 1402 South Grand Boulevard M226, St Louis, MO 63104, USA
    Psychopharmacol Bull 37:43-53. 2003
  4. ncbi request reprint Antiepileptic drugs and neuroprotection: current status and future roles
    L James Willmore
    Department of Neurology, Saint Louis University School of Medicine, St Louis, MO, USA
    Epilepsy Behav 7:S25-8. 2005
  5. ncbi request reprint Molecular biology and genetics of epilepsy
    L James Willmore
    Department of Neurology, Saint Louis University School of Medicine, USA
    Acta Med Okayama 56:57-68. 2002
  6. ncbi request reprint Genetics of epilepsy
    L James Willmore
    Department of Neurology, Saint Louis University School of Medicine, St Louis, MO 63104, USA
    J Child Neurol 17:S18-27. 2002
  7. ncbi request reprint Treatment of benign epilepsy syndromes throughout life
    L J Willmore
    Department of Neurology, Saint Louis University School of Medicine, St Louis, Missouri, USA
    Epilepsia 42:6-9. 2001
  8. ncbi request reprint Losigamone. Dr Willmar Schwabe
    L J Willmore
    Department of Neurology, Saint Louis University School of Medicine, MO 63104, USA
    Curr Opin Investig Drugs 2:1763-6. 2001
  9. ncbi request reprint Choice and use of newer anticonvulsant drugs in older patients
    L J Willmore
    Department of Neurology, Saint Louis University School of Medicine, Missouri 63104, USA
    Drugs Aging 17:441-52. 2000
  10. ncbi request reprint Zonisamide overview of the United States experience
    L James Willmore
    Saint Louis University School of Medicine, 1402 South Grand Boulevard M226, St Louis, MO 63104, USA
    Seizure 13:S57-8. 2004

Detail Information

Publications20

  1. doi request reprint Posttraumatic epilepsy: hemorrhage, free radicals and the molecular regulation of glutamate
    L J Willmore
    Department of Neurology and Psychiatry, Saint Louis University School of Medicine, 1402 South Grand Blvd, St Louis, MI 63104, USA
    Neurochem Res 34:688-97. 2009
    ..Administration of antioxidants to animals causes interruption of the sequence of brain injury responses induced by hemorrhage, suggesting that such a strategy needs to be evaluated in patients with traumatic brain injury...
  2. doi request reprint Monitoring and antiepileptic drug safety
    L James Willmore
    Saint Louis University School of Medicine, 1402 South Grand Boulevard C 130, St Louis, MO 63104 1004, USA
    Continuum (Minneap Minn) 19:801-5. 2013
    ..This review provides guidance regarding designing a monitoring strategy for patients requiring chronic treatment with antiepileptic drugs...
  3. ncbi request reprint Divalproex and epilepsy
    L James Willmore
    Saint Louis University School of Medicine, 1402 South Grand Boulevard M226, St Louis, MO 63104, USA
    Psychopharmacol Bull 37:43-53. 2003
    ..Adverse effects include hepatotoxicity that requires informing patients and establishing clinical monitoring plans. Teratogenicity occurs with valproate and requires informing patients and careful monitoring in women during pregnancy...
  4. ncbi request reprint Antiepileptic drugs and neuroprotection: current status and future roles
    L James Willmore
    Department of Neurology, Saint Louis University School of Medicine, St Louis, MO, USA
    Epilepsy Behav 7:S25-8. 2005
    ..The future of neuroprotection may involve established and newer AEDs, as well as other compounds, such as immunophilins, caspase inhibitors, endocannabinoids, and antioxidants...
  5. ncbi request reprint Molecular biology and genetics of epilepsy
    L James Willmore
    Department of Neurology, Saint Louis University School of Medicine, USA
    Acta Med Okayama 56:57-68. 2002
    ..Molecular methodology is beginning to have impact on understanding of the mechanisms of actions of drugs used to treat epilepsy and will have an impact on how future treatments are designed...
  6. ncbi request reprint Genetics of epilepsy
    L James Willmore
    Department of Neurology, Saint Louis University School of Medicine, St Louis, MO 63104, USA
    J Child Neurol 17:S18-27. 2002
    ....
  7. ncbi request reprint Treatment of benign epilepsy syndromes throughout life
    L J Willmore
    Department of Neurology, Saint Louis University School of Medicine, St Louis, Missouri, USA
    Epilepsia 42:6-9. 2001
    ..Treatment decisions require clinical judgment and observations over time. Drug selection is governed more by experience of individual clinicians, because benign syndromes occur infrequently and prospective studies are seldom performed...
  8. ncbi request reprint Losigamone. Dr Willmar Schwabe
    L J Willmore
    Department of Neurology, Saint Louis University School of Medicine, MO 63104, USA
    Curr Opin Investig Drugs 2:1763-6. 2001
    ..Another suggested possible mechanism of action for losigamone is K+ channel activation...
  9. ncbi request reprint Choice and use of newer anticonvulsant drugs in older patients
    L J Willmore
    Department of Neurology, Saint Louis University School of Medicine, Missouri 63104, USA
    Drugs Aging 17:441-52. 2000
    ..Newer anticonvulsant drugs have advantages that may outweigh risks and have therapeutic profiles that may aid in the treatment of this special population of patients...
  10. ncbi request reprint Zonisamide overview of the United States experience
    L James Willmore
    Saint Louis University School of Medicine, 1402 South Grand Boulevard M226, St Louis, MO 63104, USA
    Seizure 13:S57-8. 2004
  11. ncbi request reprint MRI-based high-dimensional hippocampal mapping in mesial temporal lobe epilepsy
    R Edward Hogan
    Department of Neurology, Saint Louis University, 1221 S Grand, 1st Floor, Epilepsy Offices, St Louis, MO 63104, USA
    Brain 127:1731-40. 2004
    ..Contralateral hippocampi show different HDM-LD changes, suggesting that the underlying disease process in the contralateral hippocampi is different from MTS...
  12. ncbi request reprint Oxcarbazepine: double-blind, randomized, placebo-control, monotherapy trial for partial seizures
    S C Schachter
    Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    Neurology 52:732-7. 1999
    ..To evaluate the efficacy and safety of oxcarbazepine in a placebo-control trial...
  13. ncbi request reprint Idiopathic cardiac asystole presenting as an intractable adult onset partial seizure disorder
    V Venkataraman
    Texas Comprehensive Epilepsy Program, Department of Neurology, University of Texas Houston, 77030, USA
    Seizure 10:359-64. 2001
    ..Early video-EEG and ECG monitoring is essential in adults with intractable seizure disorders...
  14. ncbi request reprint Vigabatrin: 2008 update
    L James Willmore
    Department of Neurology and Psychiatry, Saint Louis University School of Medicine, Saint Louis, Missouri 63104, USA
    Epilepsia 50:163-73. 2009
    ....
  15. ncbi request reprint Effect of zonisamide on molecular regulation of glutamate and GABA transporter proteins during epileptogenesis in rats with hippocampal seizures
    Yuto Ueda
    Department of Psychiatry, Miyazaki Medical College, 5200 Kihara, Kiyotake, Miyazaki 889 1692, Japan
    Brain Res Mol Brain Res 116:1-6. 2003
    ..Molecular effects on regulation of transporter proteins may aid in understanding epileptogenesis and inform investigators about future design and development of drugs to treat epilepsy...
  16. ncbi request reprint Effect of levetiracetam on molecular regulation of hippocampal glutamate and GABA transporters in rats with chronic seizures induced by amygdalar FeCl3 injection
    Yuto Ueda
    Section of Psychiatry, Department of Clinical Neuroscience, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889 1692, Japan
    Brain Res 1151:55-61. 2007
    ..These observations together demonstrated the critical molecular mechanism of the anti-epileptic activity of LEV...
  17. ncbi request reprint In vivo EPR estimation of bilateral hippocampal antioxidant ability of rats with epileptogenesis induced by amygdalar FeCl3 microinjection
    Yuto Ueda
    Section of Psychiatry, Department of Clinical Neuroscience, University of Miyazaki, Miyazaki, Japan
    Epilepsia 48:1947-51. 2007
    ....
  18. ncbi request reprint Molecular regulation of glutamate and GABA transporter proteins by clobazam during epileptogenesis in Fe(+++)-induced epileptic rats
    Taku Doi
    Department of Psychiatry, Miyazaki Medical College, 5200 Kihara, Kiyotake, Miyazaki 889 1692, Japan
    Brain Res Mol Brain Res 142:91-6. 2005
    ..In addition to allosteric activation of GABA(A) receptors, this study suggests that CLB might exhibit its antiepileptic action by increasing GLT-1 expression and GAT3 in the hippocampus of rats with chronic seizures...
  19. ncbi request reprint Functional role for redox in the epileptogenesis: molecular regulation of glutamate in the hippocampus of FeCl3-induced limbic epilepsy model
    Yuto Ueda
    Section of Psychiatry, Department of Clinical Neuroscience, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889 1692, Japan
    Exp Brain Res 181:571-7. 2007
    ....
  20. ncbi request reprint Natural antioxidants may prevent posttraumatic epilepsy: a proposal based on experimental animal studies
    Akitane Mori
    Okayama University, Okayama 700 8558, Japan
    Acta Med Okayama 58:111-8. 2004
    ..and Guilingji, have been demonstrated to scavenge ROS and/or RNS and to be prophylactic for the occurrence of epileptic discharge in the iron-injected rat brain...