A D Mooradian

Summary

Affiliation: Saint Louis University
Country: USA

Publications

  1. ncbi Cardiovascular disease in type 2 diabetes mellitus: current management guidelines
    Arshag D Mooradian
    Division of Endocrinology, Department of Internal Medicine, St Louis University School of Medicine, St Louis, MO 63104, USA
    Arch Intern Med 163:33-40. 2003
  2. ncbi Apolipoprotein A-I expression in rats is not altered by troglitazone
    Arshag D Mooradian
    The Division of Endocrinology, Diabetes, and Metabolism, Department of Internal Medicine, St Louis University Medical School, St Louis, MO 63104, USA
    Exp Biol Med (Maywood) 227:1001-5. 2002
  3. ncbi Transcriptional control of apolipoprotein A-I gene expression in diabetes
    Arshag D Mooradian
    Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, Missouri, USA
    Diabetes 53:513-20. 2004
  4. ncbi Towards single-tablet therapy for type 2 diabetes mellitus. Rationale and recent developments
    Arshag D Mooradian
    Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, Missouri, USA
    Treat Endocrinol 3:279-87. 2004
  5. ncbi The role of thiazolidinediones in the treatment of patients with type 2 diabetes mellitus
    Arshag D Mooradian
    Division of Endocrinology, Saint Louis University School of Medicine, St Louis, Missouri 63104, USA
    Treat Endocrinol 1:13-20. 2002
  6. ncbi Statins ameliorate endothelial barrier permeability changes in the cerebral tissue of streptozotocin-induced diabetic rats
    Arshag D Mooradian
    Division of Endocrinology, Diabetes and Metabolism, Saint Louis University Medical School, St Louis, MO 63104, USA
    Diabetes 54:2977-82. 2005
  7. ncbi Obesity: a rational target for managing diabetes mellitus
    A D Mooradian
    Department of Internal Medicine, Saint Louis University School of Medicine, MO 63110, USA
    Growth Horm IGF Res 11:S79-83. 2001
  8. ncbi The effect of select nutrients on serum high-density lipoprotein cholesterol and apolipoprotein A-I levels
    Arshag D Mooradian
    Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, St Louis University School of Medicine, 1402 South Grand Boulevard, St Louis, Missouri 63104, USA
    Endocr Rev 27:2-16. 2006
  9. ncbi Malondialdehyde modification of proteins in vitro is enhanced in the presence of acetaldehyde
    A D Mooradian
    Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, Saint Louis University School of Medicine, St Louis, Missouri 63110, USA
    Nutrition 17:619-22. 2001
  10. ncbi Age-related changes in plasma leptin binding activity in rats: A comparison of a simple acid-ethanol precipitation technique with column chromatography
    A D Mooradian
    Division of Endocrinology, Diabetes, and Metabolism, Department of Internal Medicine, Saint Louis University School of Medicine, St Louis, Missouri 63104, USA
    Proc Soc Exp Biol Med 224:273-7. 2000

Collaborators

Detail Information

Publications67

  1. ncbi Cardiovascular disease in type 2 diabetes mellitus: current management guidelines
    Arshag D Mooradian
    Division of Endocrinology, Department of Internal Medicine, St Louis University School of Medicine, St Louis, MO 63104, USA
    Arch Intern Med 163:33-40. 2003
    ..In this communication, some of these landmark studies are reviewed and some practical guidelines of management are suggested...
  2. ncbi Apolipoprotein A-I expression in rats is not altered by troglitazone
    Arshag D Mooradian
    The Division of Endocrinology, Diabetes, and Metabolism, Department of Internal Medicine, St Louis University Medical School, St Louis, MO 63104, USA
    Exp Biol Med (Maywood) 227:1001-5. 2002
    ..However, peroxisome proliferator activator receptor (PPAR) agonists that have significant PPAR alpha activity in addition to their PPAR gamma effects, may well be able to induce apoA-I expression...
  3. ncbi Transcriptional control of apolipoprotein A-I gene expression in diabetes
    Arshag D Mooradian
    Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, Missouri, USA
    Diabetes 53:513-20. 2004
    ..Identifying the mechanisms that modulate apo A-I gene expression will aid in the new development of therapeutic agents that increase plasma apo A-I and HDL concentrations...
  4. ncbi Towards single-tablet therapy for type 2 diabetes mellitus. Rationale and recent developments
    Arshag D Mooradian
    Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, Missouri, USA
    Treat Endocrinol 3:279-87. 2004
    ..The advantages of combining several agents in one tablet include convenience and enhanced adherence to therapy. The main disadvantage is the loss of administration flexibility...
  5. ncbi The role of thiazolidinediones in the treatment of patients with type 2 diabetes mellitus
    Arshag D Mooradian
    Division of Endocrinology, Saint Louis University School of Medicine, St Louis, Missouri 63104, USA
    Treat Endocrinol 1:13-20. 2002
    ..However, the lack of a long-term safety record, and the cost, would limit the widespread acceptance of this class of agents as first-line therapy...
  6. ncbi Statins ameliorate endothelial barrier permeability changes in the cerebral tissue of streptozotocin-induced diabetic rats
    Arshag D Mooradian
    Division of Endocrinology, Diabetes and Metabolism, Saint Louis University Medical School, St Louis, MO 63104, USA
    Diabetes 54:2977-82. 2005
    ....
  7. ncbi Obesity: a rational target for managing diabetes mellitus
    A D Mooradian
    Department of Internal Medicine, Saint Louis University School of Medicine, MO 63110, USA
    Growth Horm IGF Res 11:S79-83. 2001
    ..Treatment of obesity is an important therapeutic goal in the management of patients with type 2 diabetes mellitus...
  8. ncbi The effect of select nutrients on serum high-density lipoprotein cholesterol and apolipoprotein A-I levels
    Arshag D Mooradian
    Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, St Louis University School of Medicine, 1402 South Grand Boulevard, St Louis, Missouri 63104, USA
    Endocr Rev 27:2-16. 2006
    ..Because there are multiple mechanisms involved in the regulation of serum HDLc levels, changes in gene transcription do not necessarily correlate with clinical observations on serum levels of HDLc...
  9. ncbi Malondialdehyde modification of proteins in vitro is enhanced in the presence of acetaldehyde
    A D Mooradian
    Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, Saint Louis University School of Medicine, St Louis, Missouri 63110, USA
    Nutrition 17:619-22. 2001
    ..These in vitro observations suggest that the putative cardioprotective effects of alcohol or wine cannot be ascribed to AA-mediated reduction in MDA protein formation, a possible biochemical pathway of accelerated atherosclerosis...
  10. ncbi Age-related changes in plasma leptin binding activity in rats: A comparison of a simple acid-ethanol precipitation technique with column chromatography
    A D Mooradian
    Division of Endocrinology, Diabetes, and Metabolism, Department of Internal Medicine, Saint Louis University School of Medicine, St Louis, Missouri 63104, USA
    Proc Soc Exp Biol Med 224:273-7. 2000
    ..It is concluded that aging in rats is associated with relative insensitivity to leptin. This change cannot be attributed to increased plasma binding or to a reduction in the leptin free fraction...
  11. ncbi Ascorbic acid and alpha-tocopherol down-regulate apolipoprotein A-I gene expression in HepG2 and Caco-2 cell lines
    Arshag D Mooradian
    Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, Saint Louis University School of Medicine, St Louis, MO 63104, USA
    Metabolism 55:159-67. 2006
    ..The previously described ARE is not a response element for the ascorbate or alpha-tocopherol...
  12. ncbi Management of the cardinal features of andropause
    Arshag D Mooradian
    Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, Saint Louis University, St Louis, MO 63104, USA
    Am J Ther 13:145-60. 2006
    ..Many with erectile failure, suffer silently regardless of its etiology. In this review, we suggest some practical guidelines for the management of these conditions...
  13. ncbi Low serum high-density lipoprotein cholesterol in obese subjects with normal serum triglycerides: the role of insulin resistance and inflammatory cytokines
    A D Mooradian
    Department of Internal Medicine, Division of Endocrinology, Diabetes and Metabolism, Saint Louis University School of Medicine, Saint Louis, MO 63104, USA
    Diabetes Obes Metab 9:441-3. 2007
    ..The cause of obesity-related low HDLc in the absence of hypertriglyceridemia is not known...
  14. ncbi Age-related changes in rat cerebral occludin and zonula occludens-1 (ZO-1)
    Arshag D Mooradian
    Department of Internal Medicine, Division of Endocrinology, Diabetes and Metabolism, St Louis University School of Medicine, 1402 South Grand Blvd, St Louis, MO 63104, USA
    Mech Ageing Dev 124:143-6. 2003
    ..280+/-0.030 vs. 0.956+/-0.038), P<0.001. It is concluded that aging in rats may alter the molecular anatomy of the BBB by altering the content of select structural proteins of tight junctions...
  15. ncbi Monosaccharide-enriched diets cause hyperleptinemia without hypophagia
    A D Mooradian
    From the Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, Saint Louis University Medical School, St Louis MO 63104, USA
    Nutrition 16:439-41. 2000
    ..We conclude that monosaccharide-enriched diets, probably through hyperinsulinemia or relative or absolute insulin resistance, cause hyperleptinemia, which does not appear to change feeding behavior...
  16. ncbi Statins ameliorate glomerular permeability changes in streptozotocin-induced diabetic rats
    Arshag D Mooradian
    Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, St Louis University School of Medicine, St Louis, Missouri, USA
    Am J Ther 14:41-5. 2007
    ..Statins reduce albumin excretion rate and retard the progression of diabetic nephropathy. Whether statins alter size selectivity of glomerular filtration in diabetic rats is not known...
  17. ncbi Regulation of apoA1 gene expression with acidosis: requirement for a transcriptional repressor
    M J Haas
    Division of Endocrinology, Diabetes, and Metabolism, Department of Internal Medicine, Saint Louis University School of Medicine, St Louis, Missouri 63110, USA
    J Mol Endocrinol 27:43-57. 2001
    ....
  18. ncbi Cyclooxygenase inhibition is associated with downregulation of apolipoprotein AI promoter activity in cultured hepatoma cell line HepG2
    Mohamad H Horani
    Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, St Louis University School of Medicine, St Louis, MO, USA
    Metabolism 53:174-81. 2004
    ..It is concluded that COX inhibition with INDO or ASA downregulates apoAI expression at the transcriptional level. This effect could not be attributed to either arachidonic acid excess or to a deficiency in various prostanoids tested...
  19. ncbi Novel translational repressor (NAT-1) expression is modified by thyroid state and age in brain and liver
    G N Shah
    Department of Internal Medicine, St Louis University Medical School, Missouri 63104, USA
    Eur J Endocrinol 139:649-53. 1998
    ..It is concluded that cerebral tissue in aging rats beyond the developmental stages, like the hepatic tissue, is associated with altered TH responsiveness...
  20. ncbi Statins prevent dextrose-induced endothelial barrier dysfunction, possibly through inhibition of superoxide formation
    Michael J Haas
    Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, Saint Louis University, St Louis, MO 63104, USA
    Diabetes 55:474-9. 2006
    ....
  21. ncbi Serum leptin response to endogenous hyperinsulinemia in aging rats
    A D Mooradian
    Department of Internal Medicine, Division of Endocrinology, Diabetes and Metabolism, Health Sciences Center, Saint Louis University School of Medicine, 1402 South Grand Boulevard, St Louis, MO 63104, USA
    Mech Ageing Dev 115:101-6. 2000
    ..The inability of aging rats to mount hyperleptinemic response to dietary changes may contribute to the age-related increase in adiposity...
  22. ncbi Effect of chromium on apolipoprotein A-I expression in HepG2 cells
    Michael J Haas
    Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, St Louis University School of Medicine, St Louis, Missouri, USA
    Nutrition 19:353-7. 2003
    ..Some but not all clinical trials have associated use of chromium supplements with improved insulin sensitivity and lipid profile including increased high-density lipoprotein cholesterol levels...
  23. ncbi Diabetes-related changes in rat cerebral occludin and zonula occludens-1 (ZO-1) expression
    Joe M Chehade
    Department of Internal Medicine, St Louis University School of Medicine, Missouri 63104, USA
    Neurochem Res 27:249-52. 2002
    ..038 respectively. These differences did not achieve statistical significance. It is concluded that diabetes alters the molecular anatomy of the tight junctions in cerebral tissue by altering the content of select structural proteins...
  24. ncbi Drug therapy of postprandial hyperglycaemia
    A D Mooradian
    Department of Internal Medicine, St Louis University Medical School, Missouri 63104, USA
    Drugs 57:19-29. 1999
    ..With the availability of agents which preferentially reduce postprandial blood glucose excursions, it is now possible to achieve glycaemic goals in a larger proportion of individuals with diabetes mellitus...
  25. ncbi Pubertal changes in serum leptin levels in adolescents with type 1 diabetes mellitus: a controlled longitudinal study
    Susan E Myers
    Department of Pediatrics, Saint Louis University School of Medicine, Saint Louis, MO, USA
    J Pediatr Endocrinol Metab 17:1653-62. 2004
    ..The potential role of leptin in initiation of pubertal development is not easily demonstrable in observational studies...
  26. ncbi Aspirin sensitivity of platelet aggregation in diabetes mellitus
    Stewart G Albert
    Department of Internal Medicine, Division of Endocrinology, Diabetes and Metabolism, Saint Louis University School of Medicine, 1402 South Grand Blvd, St Louis, MO 63104, USA
    Diabetes Res Clin Pract 70:195-9. 2005
    ..Thus, the lack of aspirin protection in diabetes may be due to undefined aspects of platelet function...
  27. ncbi Low-dose recombinant human growth hormone as adjuvant therapy to lifestyle modifications in the management of obesity
    Stewart G Albert
    Division of Endocrinology, Diabetes, and Metabolism, Department of Internal Medicine, St Louis University School of Medicine, St Louis, Missouri 63104, USA
    J Clin Endocrinol Metab 89:695-701. 2004
    ..In conclusion, in obesity, rhGH normalized IGF-I levels, induced loss of BW from BF, and improved lipid profile without untoward effects on insulin sensitivity...
  28. ncbi The effect of glucosamine on Serum HDL cholesterol and apolipoprotein AI levels in people with diabetes
    Stewart G Albert
    Department of Internal Medicine, Division of Endocrinology, Saint Louis University School of Medicine, 1402 South Grand Blvd, St Louis, MO 63104, USA
    Diabetes Care 30:2800-3. 2007
    ..The hypothesis is that the neutraceutical glucosamine, when given in conventional doses (1,500 mg/day) may increase apoAI and HDL cholesterol levels in subjects with diabetes and low HDL cholesterol...
  29. ncbi Induction of the apolipoprotein AI promoter by Sp1 is repressed by saturated fatty acids
    Michael J Haas
    Department of Internal Medicine, St Louis University School of Medicine, MO, USA
    Metabolism 53:1342-8. 2004
    ..3% +/- 1.6%). Stearic acid treatment did not alter Sp1-DNA binding as measured by gel shift analysis. Therefore, saturated fatty acids blunt Sp1 induction of apo AI promoter probably at a step beyond DNA binding...
  30. ncbi The effects of recombinant human growth hormone (rhGH) supplementation on adipokines and C-reactive protein in obese subjects
    Stewart G Albert
    Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, Saint Louis University School of Medicine, 1402 South Grand Blvd, St Louis, MO 63104, USA
    Growth Horm IGF Res 17:19-25. 2007
    ..This study was undertaken to determine whether these rhGH-induced changes occur in obese subjects during rhGH supplementation...
  31. ncbi Narrative review: a rational approach to starting insulin therapy
    Arshag D Mooradian
    St Louis University School of Medicine, St Louis, Missouri, USA
    Ann Intern Med 145:125-34. 2006
    ..The emergence of multiple insulin products has provided new opportunities to achieve diabetes control. However, the number of options has raised concerns about the optimal choices of products...
  32. pmc Cloning and characterization of a complementary DNA for a thyroid hormone-responsive protein in mature rat cerebral tissue
    G N Shah
    Division of Endocrinology, St Louis University Medical School, 1402 South Grand Blvd, St Louis, MO 63104, USA
    Biochem J 327:617-23. 1997
    ..A cDNA clone for a THR gene could provide a useful tool to study the molecular mechanisms of TH effects on cerebral tissue in adult animals...
  33. ncbi Effect of glucosamine on apolipoprotein AI mRNA stabilization and expression in HepG2 cells
    Michael J Haas
    Division of Endocrinology, Diabetes and Metabolism, Saint Louis University School of Medicine, St Louis, MO, USA
    Metabolism 53:766-71. 2004
    ..6 to 16.6 hours. These findings suggest that increases in apoAI gene expression by glucosamine occur primarily through stabilizing apoAI mRNA...
  34. ncbi Drug therapy of diabetes in the elderly
    Ralph Oiknine
    Department of Internal Medicine, St Louis University School of Medicine, 1402 South Grand Boulevard, MO, St Louis 63104, USA
    Biomed Pharmacother 57:231-9. 2003
    ..In this review, the various pharmacologic agents available for the management of diabetes will be reviewed and some pertinent clinical guidelines will be suggested...
  35. ncbi Suppression of hyperglycemia-induced superoxide formation and endothelin-1 gene expression by carvedilol
    Mohamad H Horani
    Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, Saint Louis University School of Medicine, St Louis, Missouri 63104, USA
    Am J Ther 13:2-7. 2006
    ..These findings suggest that CV not only prevents dextrose-induced SO generation in endothelial cells but may also have favorable effects on gene expression and cell survival...
  36. ncbi Inhibition of apolipoprotein AI gene expression by 1, 25-dihydroxyvitamin D3
    Kent Wehmeier
    Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, Saint Louis University School of Medicine, 1402 S Grand Blvd, St Louis, MO 63104, USA
    Biochim Biophys Acta 1737:16-26. 2005
    ..This effect requires the VDR as well as a vitamin D response element in the apo AI promoter...
  37. ncbi Aronow's "Should the NCEP III guidelines be changed in elderly and younger persons at high risk for cardiovascular events?" Commentary
    Arshag D Mooradian
    Division of Endocrinology, Department of Internal Medicine, Saint Louis University, St Louis, Missouri, USA
    J Gerontol A Biol Sci Med Sci 60:598; author reply 602. 2005
  38. ncbi Differential regulation of apolipoprotein A-I gene expression by vitamin D receptor modulators
    Kent R Wehmeier
    Division of Endocrinology, Department of Medicine, University of Florida, 653 1 West 8th Street, 4th Floor LRC, Jacksonville, FL 32209, USA
    Biochim Biophys Acta 1780:264-73. 2008
    ..Gel shift assays showed that none of the treatments resulted in a change in site A binding activity. These results indicate that VDR modulators in hepatocytes and intestinal cells differentially regulate expression of the apo A-I gene...
  39. ncbi Partial characterization of a cerebral thyroid hormone-responsive protein
    Michael J Haas
    Division of Endocrinology, Diabetes and Metabolism, St Louis University School of Medicine, St Louis, Missouri 63104, USA
    Arch Biochem Biophys 399:6-11. 2002
    ..These studies demonstrate that THRP and Abi-2 have distinct tissue distribution and distinct biological properties...
  40. ncbi Antioxidant vitamins and their influence in diabetes mellitus
    Bibi Hasanain
    Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, Saint Louis University School of Medicine, 1402 South Grand Boulevard, Saint Louis, MO 63104, USA
    Curr Diab Rep 2:448-56. 2002
    ..Given the lack of data to substantiate the benefit and safety of ingestion of antioxidant vitamins in excess of the recommended dietary allowance, physicians should avoid the recommendation of vitamin supplementation to their patients...
  41. ncbi Recent trials of antioxidant therapy: what should we be telling our patients?
    Bibi I Hasnain
    Division of Endocrinology, Diabetes, and Metabolism, Department of Internal Medicine, St Louis University School of Medicine, St Louis, MO 63104, USA
    Cleve Clin J Med 71:327-34. 2004
    ..We review important studies of the effects of four antioxidants (vitamins A, C, and E, and beta carotene) and analyze whether the current evidence supports or confirms or rejects the presumed protective role...
  42. ncbi Glucagon-like peptide-1 response to acarbose in elderly type 2 diabetic subjects
    Mary Jeanne Deleon
    Division of Endocrinology, Diabetes and Metabolism, Saint Louis University School of Medicine, 1402 South Grand Boulevard, St Louis, MO 63104, USA
    Diabetes Res Clin Pract 56:101-6. 2002
    ....
  43. doi The incidence of Hashimoto's disease in nodular goitre: the concordance in serological and cytological findings
    J M Chehade
    Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, University of Florida, College of Medicine, Jacksonville, FL 32209, USA
    Int J Clin Pract 64:29-33. 2010
    ..To determine the incidence of Hashimoto's disease in nodular goitre and to ascertain the degree of the concordance between serological and cytological findings...
  44. ncbi Effect of diabetes on the blood brain barrier
    Mohamad H Horani
    Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, MO, 63104, USA
    Curr Pharm Des 9:833-40. 2003
    ..The present communication briefly reviews the Diabetes-related changes in the central nervous system and discusses some of the mechanisms underlying these changes...
  45. ncbi Suppression of apolipoprotein AI gene expression in HepG2 cells by TNF alpha and IL-1beta
    Michael J Haas
    Department of Internal Medicine, School of Medicine, St Louis University, Health Sciences Center, 1402 S Grand Boulevard, St Louis, MO 63104, USA
    Biochim Biophys Acta 1623:120-8. 2003
    ..These studies suggest that inflammatory cytokines down-regulate apoAI expression at least partly through inhibition of binding of the nuclear factors to site A of the apoAI promoter...
  46. ncbi Inhibition of apolipoprotein AI gene expression by tumor necrosis factor alpha: roles for MEK/ERK and JNK signaling
    Ann Beers
    Division of Endocrinology, Diabetes, and Metabolism, Department of Internal Medicine, St Louis University School of Medicine, St Louis, Missouri 63104, USA
    Biochemistry 45:2408-13. 2006
    ..These results suggest that TNF alpha suppresses apoAI promoter activity through both the MEK/ERK and JNK pathways but is not mediated by either p38 MAP kinase activity or NF-kappaB activation...
  47. ncbi Saturated, unsaturated, and trans-fatty acids modulate oxidative burst induced by high dextrose in human umbilical vein endothelial cells
    Mohamad H Horani
    Division of Endocrinology, Diabetes and Metabolism, St Louis University School of Medicine, St Louis, Missouri, USA
    Nutrition 22:123-7. 2006
    ..We determined whether hyperglycemia-induced oxidative burst is augmented in the presence of saturated, unsaturated, and trans-fatty acids (FAs)...
  48. ncbi Thyroid hormone responsive protein (THRP) mediates thyroid hormone-induced cytotoxicity in primary neuronal cultures
    Michael J Haas
    Division of Endocrinology, Diabetes, and Metabolism, Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, MO 63104, USA
    Exp Brain Res 160:424-32. 2005
    ..6 compared with 145+/-16.9, P<0.05). Co-transfection of THRP with wild-type c-Abl did not alter the effect of THRP on cell survival. It is concluded that THRP is an important factor in TH-induced neuronal cell death...
  49. ncbi Microarray analysis of thyroid hormone-induced changes in mRNA expression in the adult rat brain
    Michael J Haas
    Division of Endocrinology, Diabetes and Metabolism, Saint Louis University, 1402 South Grand Blvd, St Louis, MO 63104, USA
    Neurosci Lett 365:14-8. 2004
    ..The present study underscores the paucity of TH responsive genes in adult cerebral tissue...
  50. ncbi Rapid adaptive down regulation of oxidative burst induced by high dextrose in human umbilical vein endothelial cells
    Mohamad H Horani
    Division of Endocrinology, Diabetes and Metabolism, St Louis University School of Medicine, 1402 S Grand Blvd, St Louis, MO 63104, USA
    Diabetes Res Clin Pract 66:7-12. 2004
    ..It is concluded that increased oxidative load in sustained chronic hyperglycemia is probably the result of depletion of antioxidant pool rather than secondary to sustained increase in SO production...
  51. ncbi Effects of dehydroepiandrosterone on rat apolipoprotein AI gene expression in the human hepatoma cell line, HepG2
    Mary Jeanne Deleon
    Division of Endocrinology, Diabetes, and Metabolism, Saint Louis University School of Medicine, St Louis, MO 63104, USA
    Metabolism 51:376-9. 2002
    ..It remains to be established if the transcriptional effects we observed are mediated through an androgen response element...
  52. ncbi Astrocytic and neuronal biochemical markers in the sera of subjects with diabetes mellitus
    Meri R Hovsepyan
    Department of Internal Medicine, Saint Louis University Medical School, Saint Louis, MO 63104, USA
    Neurosci Lett 369:224-7. 2004
    ..These studies suggest that diabetes in humans may be associated with alterations in the BBB integrity that allow the emergence of antibodies against neuronal antigens...
  53. ncbi Effect of growth hormone replacement on BMD in adult-onset growth hormone deficiency
    Peter J Snyder
    Division of Endocrinology, Diabetes and Metabolism, University of Pennsylvania, Philadelphia, PA 19104 6149, USA
    J Bone Miner Res 22:762-70. 2007
    ..To determine if replacement of GH improves BMD in adult-onset GHD, we administered GH in physiologic amounts to men and women with GHD. GH replacement significantly increased spine BMD in the men by 3.8%...
  54. ncbi A critical appraisal of the role of insulin analogues in the management of diabetes mellitus
    Ralph Oiknine
    Division of Endocrinology, Department of Internal Medicine, Diabetes, and Metabolism, St Louis University School of Medicine, St Louis, Missouri 63104, USA
    Drugs 65:325-40. 2005
    ..Although novel insulin analogues are promising 'designer drugs' in our armamentarium to overcome some of the limitations of conventional insulin therapy, cost may be a limiting factor for some patients...
  55. ncbi Familial dyslipidaemias: an overview of genetics, pathophysiology and management
    Sahar B Hachem
    Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, Missouri, USA
    Drugs 66:1949-69. 2006
    ..A bile acid binding agent is an option if the serum TG levels do not exceed 200 mg/dL (5.65 mmol/L), otherwise a fibrate or nicotinic acid should be considered. The decision to treat a particular person has to be individualised...
  56. ncbi Management of obesity in the elderly: special considerations
    Mohamad H Horani
    Division of Endocrinology, Department of Internal Medicine, Diabetes and Metabolism, St Louis University School of Medicine, St Louis, Missouri 63104, USA
    Treat Endocrinol 1:387-98. 2002
    ..Management should emphasize lifestyle modifications, while the use of pharmacologic agents such as sibutramine and orlistat should be reserved for select groups of patients who do not respond to lifestyle modification...
  57. ncbi Antioxidants and diabetes
    Arshag D Mooradian
    Division of Endocrinology, Diabetes, and Metabolism, Department of Internal Medicine, St Louis University School of Medicine, St Louis, MO, USA
    Nestle Nutr Workshop Ser Clin Perform Programme 11:107-22; discussion 122-5. 2006
    ..Future studies should focus on identifying reliable markers of oxidation to incorporate these measurements in the clinical interventional trial...
  58. ncbi 2006-2007 American Diabetes Association Nutrition Recommendations: issues for practice translation
    Judith Wylie-Rosett
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    J Am Diet Assoc 107:1296-304. 2007
  59. doi Obesity-related changes in high-density lipoprotein metabolism
    Arshag D Mooradian
    Department of Medicine, University of Florida College of Medicine, Jacksonville, Florida, USA
    Obesity (Silver Spring) 16:1152-60. 2008
    ..The emergence of glucose intolerance or a genetic predisposition to familial combined hyperlipidemia will further modify the plasma lipid phenotype in obese people (11,12,13,14,15)...
  60. ncbi Severe insulin resistance associated with subcutaneous amyloid deposition
    Stewart G Albert
    Diabetes Res Clin Pract 75:374-6. 2007
    ..These findings may add insight into the role of insulin-degrading enzymes in the etiology of subcutaneous insulin resistance syndromes...
  61. ncbi Nutrition principles and recommendations in diabetes
    Marion J Franz
    Diabetes Care 27:S36-46. 2004
  62. ncbi Evidence-based nutrition principles and recommendations for the treatment and prevention of diabetes and related complications
    Marion J Franz
    Diabetes Care 26:S51-61. 2003
  63. ncbi Insulin induction of apolipoprotein AI, role of Sp1
    Johnny K Lam
    Endocrine Research Group, Department of Medicine, The Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada, T2N 4N1
    Biochemistry 42:2680-90. 2003
    ..In summary, the IRCE alone can mediate the stimulatory effects of insulin, bpv, and PDBu, and Sp1 enhances these responses that may arise from phosphorylation of the protein...
  64. doi Nutrition recommendations and interventions for diabetes: a position statement of the American Diabetes Association
    John P Bantle
    Diabetes Care 31:S61-78. 2008
  65. ncbi Evidence-based nutrition principles and recommendations for the treatment and prevention of diabetes and related complications
    Marion J Franz
    Nutrition Concepts by Franz, Inc, Minneapolis, Minnesota 55439, USA
    Diabetes Care 25:148-98. 2002
  66. ncbi Asymptomatic hyperthyroidism in older adults: is it a distinct clinical and laboratory entity?
    Arshag D Mooradian
    Department of Medicine, University of Florida College of Medicine, Jacksonville, Florida 32209, USA
    Drugs Aging 25:371-80. 2008
    ..Asymptomatic hyperthyroidism may well be a syndrome that is currently under-diagnosed...
  67. ncbi Nutrition recommendations and interventions for diabetes--2006: a position statement of the American Diabetes Association
    John P Bantle
    Diabetes Care 29:2140-57. 2006