Krista L Lentine

..Prospective evaluations of the impact of targeted risk modification efforts in this population including dietary changes, monitored exercise programs, and bariatric surgery are urgently needed...

..We examined the frequency and clinical impact of acute rejection (AR) in contemporary U.S. kidney transplantation...

..Mortality records identify cancer as the leading cause of death among living kidney donors, but information on the burden of cancer outside death records is limited in this population...

..Limited data exist on correlates of psychological outcomes after kidney donation...

..The transplant community must persist in their efforts to accurately assess risk across demographically diverse living kidney donors...

..Data regarding health outcomes among living kidney donors are lacking, especially among nonwhite persons...

..Characterizing relationships of kidney function to healthcare costs in polycystic kidney disease has applications for economic evaluations of standard and emerging therapies...

..Policy makers and providers must work together to ensure that financial disincentives do not lead to wastage of lifesaving organs...

..Little is known about associations of family health history with outcomes after kidney donation...

..Limited data are available on the use of potentially cardioprotective medications among U.S. kidney transplant recipients...

..Variation in kidney transplant access across the United States may motivate relocation of patients with ability to travel to better-supplied areas...

..This study assessed the accuracy of three potential sources of maintenance immunosuppression data...

..Risk of new-onset diabetes after transplant (NODAT) is well characterized for adults but much less understood in pediatric transplant. This study examines the incidence and risk factors of NODAT in pediatric renal transplant patients...

..Retrospective comparison of treatment-related kidney transplant outcomes may be facilitated by multivariable statistical adjustments and case-matching...

..Evaluation for ischemic heart disease (IHD) is a nonstandardized practice before kidney transplantation. We retrospectively studied pretransplant cardiac evaluation (CE) practices in a national sample of renal allograft recipients...

..Innovation in renal transplant management would benefit from identification of early markers that accurately predict long-term graft survival...

..The relationship of body mass index (BMI) with heart failure (HF) risk before and after kidney transplant is not well described...

..To quantify the incremental survival benefit of the pancreas allograft in simultaneous pancreas-kidney (SPK) transplant recipients...

..Hyperuricemia is common in patients with chronic kidney disease (CKD). We assessed the relationship of increased serum uric acid levels with cardiovascular risk across levels of kidney function...

..The cardiac implications of obesity in kidney transplant recipients are not well-described...

..This study examined the risks, predictors, and mortality implications of cerebrovascular disease events after kidney transplantation in a national cohort...

..48; P = 0.0012). Whereas the incidence of NOD is greatest with high Tac dosages, the increased risk versus CsA is sustained with lower Tac dosages. Higher steroid dosages increase the early diabetogenic effect of Tac but not of CsA...

..Clinical practice guidelines for management of chronic kidney disease (CKD) have been developed within the Kidney Disease Outcomes Quality Initiative (K/DOQI). Adherence patterns may identify focus areas for quality improvement...

..The economic ramifications of acute rejection (AR) are not well characterized in a contemporary population of kidney transplant recipients...

..Limited data exist on the safety and efficacy of bariatric surgery (BS) in patients with kidney failure...

..Quantifying the relationship of renal function at 1 year after transplant with subsequent clinical outcomes and healthcare costs may facilitate cost-benefit evaluations among transplant recipients...

..We aim to describe the risk, predictors, and outcomes associated with de novo congestive heart failure (CHF) after kidney transplantation...

..Appropriate risk stratification may identify transplant recipients who are in need of close monitoring for and management of this adverse cardiovascular event...

..Therefore, increasing organ donation should be considered among our most important public health concerns...

..Our expanded methodology can be used by others to assess more accurately the financial implications of renal transplantation to Medicare and individual transplant centers...

..Post-transplant eGFR may be a useful end-point for discriminating benefits of care strategies that differentially affect renal function...

..The purpose of this article was to review these and other issues pertaining to medical insurance coverage and transplantation, particularly for adolescent recipients as they transition to adulthood...

..However, HLA-matched deceased donor recipients received lower dosages of mycophenolate mofetil and manifested a lower risk of developing posttransplant diarrhea...

..The risks of positive FCXM persist beyond the peritransplant period for years after transplant. Damage by memory effector cells may explain the long-term risks associated with positive FCXM...

..In conclusion, high-MELD patients incur significantly higher costs prior to and at the time of LT. Following LT, the MELD score is not a significant predictor of cost or re-admission...

..Risk factors for PTMI include potentially modifiable posttransplantation complications. Because PTMI in turn predicts graft failure and death, reducing the risk for PTMI may improve outcomes after kidney transplantation...

..Biomarkers, such as cardiac troponin, have prognostic value in end-stage renal disease, but require further study to determine clinical applications in directing more expensive and invasive cardiac evaluation...

..We conclude that current practice patterns have not aligned utilization of T&B FC crossmatch with associated benefits. Prospective evaluation of the relationship of crossmatch modality with outcomes is warranted...

..We examined the incidence and predictors of gastroesophageal reflux disease (GERD) and dyspepsia and their associations with graft survival and mortality after transplant...

..Low detection rates of OPTN-indicated corticosteroid use within claims require further examination...

..Few studies have described the performance of billing claims as surrogate measures of clinical events among kidney transplant recipients...

..Using less than five total years of data tended to overestimate the population's long-term survival, accurate prediction of long-term DCGS is possible, but requires attention to the quantity data used in the projection method...

..Data are scarce regarding the incidence and risk factors for complications of new-onset diabetes mellitus (NODM) in renal transplant patients...

..We investigated associations between pre-transplant comorbidities, length of stay (LOS) and Medicare payments for transplant hospitalization...

..To quantify relationships of post-transplant renal function with healthcare costs after kidney transplantation...

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..We assessed the impact of socioeconomic status (SES) and traveling to alternative donation service areas (DSAs) on patient survival...

..This case illustrates that serologic evaluation for ANCAs should not be discounted when immune deposits are present. Prompt diagnosis is warranted...

..We assessed whether current clinical evidence supports the use of statins to improve cardiac and/or renal outcomes after kidney transplantation...

..Proximal or "downhill" esophageal varices are a rare complication of superior vena caval (SVC) obstruction. Few reports describe downhill varices in dialysis patients with catheter-related SVC occlusion...

..Inflammatory markers predict cardiovascular risk and mortality in endstage renal disease. The relationship of chronic infections to inflammation and vascular disease events has not been reported among American dialysis patients...

..To describe practices for preventing venous thromboembolism in critically ill medical patients and to identify associations between prophylactic measures and survival...