Affiliation: Saint Louis University
- Zhao L, Loewenstein P, Green M. Adenovirus E1A TRRAP-targeting domain-mediated enhancement of MYC association with the NuA4 complex activates a panel of MYC target genes enriched for gene expression and ribosome biogenesis. Virology. 2017;512:172-179 pubmed publisher....
- Green M, Panesar N, Loewenstein P. The transcription-repression domain of the adenovirus E1A oncoprotein targets p300 at the promoter. Oncogene. 2008;27:4446-55 pubmed publisher..These findings provide support for the hypothesis that p300 can serve as a scaffold for the E1A repression domain to access specific cellular gene promoters involved in growth regulation. ..
- Zhao L, Loewenstein P, Green M. Ad E1A 243R oncoprotein promotes association of proto-oncogene product MYC with the NuA4/Tip60 complex via the E1A N-terminal repression domain. Virology. 2016;499:178-184 pubmed publisher..Significantly, E1A 243R promotes association of MYC/MAX with the NuA4/Tip60 complex, implicating the importance of the MYC/NuA4 pathway in cellular transformation by both MYC and E1A. ..