Sarah L George

Summary

Affiliation: Saint Louis University
Country: USA

Publications

  1. pmc The GB virus C (GBV-C) NS3 serine protease inhibits HIV-1 replication in a CD4+ T lymphocyte cell line without decreasing HIV receptor expression
    Sarah L George
    Division of Infectious Diseases, Department of Internal Medicine, St Louis University, St Louis, Missouri, United States of America
    PLoS ONE 7:e30653. 2012
  2. ncbi request reprint What you need to know about GB virus C
    Sarah L George
    Division of Infectious Diseases, Saint Louis University School of Medicine, FDT 8N, 3635 Vista Avenue, St Louis, MO 63110, USA
    Curr Gastroenterol Rep 7:54-62. 2005
  3. ncbi request reprint GB virus C replicates in primary T and B lymphocytes
    Sarah L George
    Research Service and Department of Internal Medicine, Saint Louis University Hospital and St Louis Veterans Affairs Medical Center, MO 63110, USA
    J Infect Dis 193:451-4. 2006
  4. pmc Clinical, virologic, histologic, and biochemical outcomes after successful HCV therapy: a 5-year follow-up of 150 patients
    Sarah L George
    Department of Internal Medicine, Division of Gastroenterology, Saint Louis University Liver Center, St Louis, MO, USA
    Hepatology 49:729-38. 2009
  5. ncbi request reprint Hepatitis C virus viremia in HIV-infected individuals with negative HCV antibody tests
    Sarah L George
    Department of Internal Medicine, Iowa City Veterans Administration Medical Center, University of Iowa, College of Medicine, 52242, USA
    J Acquir Immune Defic Syndr 31:154-62. 2002
  6. ncbi request reprint Inhibition of HIV-1 replication by GB virus C infection through increases in RANTES, MIP-1alpha, MIP-1beta, and SDF-1
    Jinhua Xiang
    Research Service and Department of Internal Medicine, Iowa City VA Medical Center and University of Iowa, Iowa City, IA, USA
    Lancet 363:2040-6. 2004
  7. ncbi request reprint Recombinant hepatitis C virus-like particles expressed by baculovirus: utility in cell-binding and antibody detection assays
    Jinhua Xiang
    Department of Internal Medicine, Iowa City Veterans Administration Medical Center, Iowa City, Iowa, USA
    J Med Virol 68:537-43. 2002
  8. ncbi request reprint Clinical isolates of GB virus type C vary in their ability to persist and replicate in peripheral blood mononuclear cell cultures
    Sarah L George
    Departments of Internal Medicine and Research, Iowa City VA Medical Center, University of Iowa, and the Helen C Levitt Center for Viral Pathogenesis, Iowa City, IA 52242, USA
    Virology 316:191-201. 2003
  9. ncbi request reprint Persistent GB virus C infection is associated with decreased HIV-1 disease progression in the Amsterdam Cohort Study
    Sarah L George
    J Infect Dis 191:2156-7; author reply 2158-60. 2005

Detail Information

Publications9

  1. pmc The GB virus C (GBV-C) NS3 serine protease inhibits HIV-1 replication in a CD4+ T lymphocyte cell line without decreasing HIV receptor expression
    Sarah L George
    Division of Infectious Diseases, Department of Internal Medicine, St Louis University, St Louis, Missouri, United States of America
    PLoS ONE 7:e30653. 2012
    ..Two GBV-C proteins, NS5A and E2, have been shown previously to inhibit HIV replication in vitro. We investigated whether the GBV-C NS3 serine protease affects HIV replication...
  2. ncbi request reprint What you need to know about GB virus C
    Sarah L George
    Division of Infectious Diseases, Saint Louis University School of Medicine, FDT 8N, 3635 Vista Avenue, St Louis, MO 63110, USA
    Curr Gastroenterol Rep 7:54-62. 2005
    ..GBV-C E2 protein in serum has also been associated with prolonged survival in HIV infection; recent evidence indicates that GBV-C E2 protein may neutralize HIV infection in vitro...
  3. ncbi request reprint GB virus C replicates in primary T and B lymphocytes
    Sarah L George
    Research Service and Department of Internal Medicine, Saint Louis University Hospital and St Louis Veterans Affairs Medical Center, MO 63110, USA
    J Infect Dis 193:451-4. 2006
    ....
  4. pmc Clinical, virologic, histologic, and biochemical outcomes after successful HCV therapy: a 5-year follow-up of 150 patients
    Sarah L George
    Department of Internal Medicine, Division of Gastroenterology, Saint Louis University Liver Center, St Louis, MO, USA
    Hepatology 49:729-38. 2009
    ..No patient had conclusive evidence of virologic relapse. Three patients had persistently elevated alanine aminotransferase levels; two of these had new liver disease...
  5. ncbi request reprint Hepatitis C virus viremia in HIV-infected individuals with negative HCV antibody tests
    Sarah L George
    Department of Internal Medicine, Iowa City Veterans Administration Medical Center, University of Iowa, College of Medicine, 52242, USA
    J Acquir Immune Defic Syndr 31:154-62. 2002
    ....
  6. ncbi request reprint Inhibition of HIV-1 replication by GB virus C infection through increases in RANTES, MIP-1alpha, MIP-1beta, and SDF-1
    Jinhua Xiang
    Research Service and Department of Internal Medicine, Iowa City VA Medical Center and University of Iowa, Iowa City, IA, USA
    Lancet 363:2040-6. 2004
    ..This study provides insight into the epidemiological association between GBV-C infection and longer survival in HIV-infected individuals...
  7. ncbi request reprint Recombinant hepatitis C virus-like particles expressed by baculovirus: utility in cell-binding and antibody detection assays
    Jinhua Xiang
    Department of Internal Medicine, Iowa City Veterans Administration Medical Center, Iowa City, Iowa, USA
    J Med Virol 68:537-43. 2002
    ..In addition, HCV VLPs seem useful for evaluating HCV-cell interactions...
  8. ncbi request reprint Clinical isolates of GB virus type C vary in their ability to persist and replicate in peripheral blood mononuclear cell cultures
    Sarah L George
    Departments of Internal Medicine and Research, Iowa City VA Medical Center, University of Iowa, and the Helen C Levitt Center for Viral Pathogenesis, Iowa City, IA 52242, USA
    Virology 316:191-201. 2003
    ..Since GBV-C appears to inhibit HIV replication in a coinfection model, these studies should facilitate determination of the mechanism of this interaction...
  9. ncbi request reprint Persistent GB virus C infection is associated with decreased HIV-1 disease progression in the Amsterdam Cohort Study
    Sarah L George
    J Infect Dis 191:2156-7; author reply 2158-60. 2005