Barrie P BodeSummaryAffiliation: Saint Louis University Country: USA Publications
Research Grants
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Detail Information
Publications
Inducible antisense RNA targeting amino acid transporter ATB0/ASCT2 elicits apoptosis in human hepatoma cellsBryan C Fuchs
Deptartment of Biology, St Louis University, St Louis, MO 63103 2010, USA
Am J Physiol Gastrointest Liver Physiol 286:G467-78. 2004..We conclude that ATB(0)/ASCT2 expression is necessary for SK-Hep cell growth and viability and suggest that it be further explored as a selective target for human hepatocellular carcinoma...
Molecular and functional analysis of glutamine uptake in human hepatoma and liver-derived cellsBarrie P Bode
Surgical Oncology Research Laboratories, Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
Am J Physiol Gastrointest Liver Physiol 283:G1062-73. 2002....
ASCT2 silencing regulates mammalian target-of-rapamycin growth and survival signaling in human hepatoma cellsBryan C Fuchs
Dept of Biology, Saint Louis University, 3507 Laclede Ave, St Louis, MO 63103 2010, USA
Am J Physiol Cell Physiol 293:C55-63. 2007..These results suggest that ASCT2 silencing inhibits mTORC1 signaling to the translational machinery followed by an mTORC2-initiated survival response, establishing a link between amino acid transporter expression and mTOR function...
Amino acid transporters ASCT2 and LAT1 in cancer: partners in crime?Bryan C Fuchs
Department of Biology, Saint Louis University, MW128, 3507 Laclede Avenue, St Louis, MO 63103 2010, USA
Semin Cancer Biol 15:254-66. 2005....
Stressing out over survival: glutamine as an apoptotic modulatorBryan C Fuchs
Department of Biology, Saint Louis University, St. Louis, MO 63103-2010, USA
J Surg Res 131:26-40. 2006..These results have collectively provided testable hypotheses for further in vivo studies into their physiological relevance during GLN "nutritional pharmacology."..
Type I diabetes affects skeletal muscle glutamine uptake in a fiber-specific mannerMarie C Onan
Department of Biology, Saint Louis University, St. Louis, MO 63103-2010, USA
Exp Biol Med (Maywood) 230:606-11. 2005..This represents the first report of differential fiber-specific effects of diabetes on skeletal muscle glutamine transport and the co-expression of distinct System N transporters in skeletal muscle...
Research Grants
- ASCT2 in Human Liver Cancer Cell Growth and SurvivalBARRIE BODE; Fiscal Year: 2005..abstract_text> ..
