Affiliation: Saint Louis University
- Reduced-intensity conditioning is effective and safe for transplantation of patients with Shwachman-Diamond syndromeD Bhatla
Department of Hematology Oncology, Cincinnati Children s Hospital and Medical Center, Cincinnati, OH, USA
Bone Marrow Transplant 42:159-65. 2008..All patients are currently alive. These data indicate that HSCT with reduced-intensity conditioning is feasible in patients with SDS and associated with excellent donor cell engraftment and modest morbidity...
- Cytidine deaminase genotype and toxicity of cytosine arabinoside therapy in children with acute myeloid leukemiaDeepika Bhatla
Division of Hematology Oncology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
Br J Haematol 144:388-94. 2009..59 +/- 12% AA and 55 +/- 14% AC; P = 0.40). These data indicate that children with a low activity CDA genotype are at increased risk of TRM with ara-C based therapy for AML...
- MDM2 polymorphism increases susceptibility to childhood acute myeloid leukemia: a report from the Children's Oncology GroupChristine L Phillips
Division of Hematology Oncology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
Pediatr Blood Cancer 55:248-53. 2010..In addition, cells homozygous (G/G) for SNP 309 were found to have 10-fold increase resistance to topoisomerase II inhibitors in vitro...