Daniel E Ryan

Summary

Country: USA

Publications

  1. pmc New tertiary constraints between the RNA components of active yeast spliceosomes: a photo-crosslinking study
    Daniel E Ryan
    Division of Biology 147 75, California Institute of Technology, Pasedena 91125, USA
    RNA 10:1251-65. 2004
  2. pmc The 5' and 3' domains of yeast U6 snRNA: Lsm proteins facilitate binding of Prp24 protein to the U6 telestem region
    Daniel E Ryan
    Division of Biology, California Institute of Technology, Pasadena 91125, USA
    RNA 8:1011-33. 2002
  3. pmc The conserved central domain of yeast U6 snRNA: importance of U2-U6 helix Ia in spliceosome assembly
    Daniel E Ryan
    Division of Biology, California Institute of Technology, Pasadena 91125, USA
    RNA 8:997-1010. 2002
  4. ncbi request reprint Composition and functional characterization of the yeast spliceosomal penta-snRNP
    Scott W Stevens
    California Institute of Technology, Division of Biology 147 75, Pasadena, CA 91125, USA
    Mol Cell 9:31-44. 2002

Collaborators

  • John Abelson
  • Scott W Stevens
  • Helen Y Ge
  • Mary K Young
  • Roger E Moore
  • Terry D Lee

Detail Information

Publications4

  1. pmc New tertiary constraints between the RNA components of active yeast spliceosomes: a photo-crosslinking study
    Daniel E Ryan
    Division of Biology 147 75, California Institute of Technology, Pasedena 91125, USA
    RNA 10:1251-65. 2004
    ..This latter set of crosslinks formed across U2-U6 helix I. Importantly, this set provides new tertiary constraints for developing 3D models of fully assembled yeast spliceosomes, which are poised for the first chemical step of splicing...
  2. pmc The 5' and 3' domains of yeast U6 snRNA: Lsm proteins facilitate binding of Prp24 protein to the U6 telestem region
    Daniel E Ryan
    Division of Biology, California Institute of Technology, Pasadena 91125, USA
    RNA 8:1011-33. 2002
    ..We present a revised secondary structural model of yeast U6 snRNA in free U6 snRNPs...
  3. pmc The conserved central domain of yeast U6 snRNA: importance of U2-U6 helix Ia in spliceosome assembly
    Daniel E Ryan
    Division of Biology, California Institute of Technology, Pasadena 91125, USA
    RNA 8:997-1010. 2002
    ..Base pairing of the U6 3' stem-loop in yeast spliceosomes does not extend as far as to include the U6 sequence of U2-U6 helix Ib, in contrast to the human U6 3' stem-loop structure...
  4. ncbi request reprint Composition and functional characterization of the yeast spliceosomal penta-snRNP
    Scott W Stevens
    California Institute of Technology, Division of Biology 147 75, Pasadena, CA 91125, USA
    Mol Cell 9:31-44. 2002
    ..We propose that the spliceosomal snRNPs associate prior to binding of a pre-mRNA substrate rather than with pre-mRNA via stepwise addition of discrete snRNPs...