Helmut Zarbl

Summary

Affiliation: Rutgers University
Country: USA

Publications

  1. ncbi Toxicogenomic analyses of genetic susceptibility to mammary gland carcinogenesis in rodents: implications for human breast cancer
    Helmut Zarbl
    Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Rutgers University, Piscataway, NJ 08854, USA
    Breast Dis 28:87-105. 2007
  2. ncbi The vanishing zero revisited: thresholds in the age of genomics
    Helmut Zarbl
    Environmental and Occupational Health Sciences Institute, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway, NJ 08854, USA
    Chem Biol Interact 184:273-8. 2010
  3. ncbi Comparative genomics of susceptibility to mammary carcinogenesis among inbred rat strains: role of reduced prolactin signaling in resistance of the Copenhagen strain
    Xuefeng Ren
    Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Carcinogenesis 29:177-85. 2008

Research Grants

  1. MAPPING GENETIC SUPPRESSORS OF EPIGENETIC CARCINOGENESIS
    Helmut Zarbl; Fiscal Year: 2002
  2. The FHCRC/UW Toxicogenomics Consortium
    Helmut Zarbl; Fiscal Year: 2006

Collaborators

  • Xuefeng Ren
  • Andrea S Kim
  • Robert C Sullivan
  • Roger E Bumgarner
  • Andrei M Mikheev
  • Mingzhu Fang
  • Xun Zhang

Detail Information

Publications3

  1. ncbi Toxicogenomic analyses of genetic susceptibility to mammary gland carcinogenesis in rodents: implications for human breast cancer
    Helmut Zarbl
    Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Rutgers University, Piscataway, NJ 08854, USA
    Breast Dis 28:87-105. 2007
    ..In the present review, we explore how the combination of toxicogenomic approaches with rodent models can accelerate the discovery of human breast cancer susceptibility genes...
  2. ncbi The vanishing zero revisited: thresholds in the age of genomics
    Helmut Zarbl
    Environmental and Occupational Health Sciences Institute, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway, NJ 08854, USA
    Chem Biol Interact 184:273-8. 2010
    ..This treatise explores how toxicogenomic responses at low doses may inform risk assessment and risk management by defining thresholds for cellular responses linked to modes or mechanisms of toxicity at the molecular level...
  3. ncbi Comparative genomics of susceptibility to mammary carcinogenesis among inbred rat strains: role of reduced prolactin signaling in resistance of the Copenhagen strain
    Xuefeng Ren
    Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Carcinogenesis 29:177-85. 2008
    ..Together, these finding indicated that in the rat, the molecular mechanisms underlying genetic susceptibility to mammary carcinogenesis include de-regulation of Prl signaling...

Research Grants7

  1. MAPPING GENETIC SUPPRESSORS OF EPIGENETIC CARCINOGENESIS
    Helmut Zarbl; Fiscal Year: 2002
    ....
  2. The FHCRC/UW Toxicogenomics Consortium
    Helmut Zarbl; Fiscal Year: 2006
    ..The latter will be essential for the generation of a public database for data generated by all members of the Consortium. ..