Affiliation: Rutgers University
- Toxicogenomic analyses of genetic susceptibility to mammary gland carcinogenesis in rodents: implications for human breast cancerHelmut Zarbl
Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Rutgers University, Piscataway, NJ 08854, USA
Breast Dis 28:87-105. 2007..In the present review, we explore how the combination of toxicogenomic approaches with rodent models can accelerate the discovery of human breast cancer susceptibility genes...
- The vanishing zero revisited: thresholds in the age of genomicsHelmut Zarbl
Environmental and Occupational Health Sciences Institute, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway, NJ 08854, USA
Chem Biol Interact 184:273-8. 2010..This treatise explores how toxicogenomic responses at low doses may inform risk assessment and risk management by defining thresholds for cellular responses linked to modes or mechanisms of toxicity at the molecular level...
- Comparative genomics of susceptibility to mammary carcinogenesis among inbred rat strains: role of reduced prolactin signaling in resistance of the Copenhagen strainXuefeng Ren
Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Carcinogenesis 29:177-85. 2008..Together, these finding indicated that in the rat, the molecular mechanisms underlying genetic susceptibility to mammary carcinogenesis include de-regulation of Prl signaling...
- MAPPING GENETIC SUPPRESSORS OF EPIGENETIC CARCINOGENESISHelmut Zarbl; Fiscal Year: 2002....
- The FHCRC/UW Toxicogenomics ConsortiumHelmut Zarbl; Fiscal Year: 2006..The latter will be essential for the generation of a public database for data generated by all members of the Consortium. ..