Research Topics
Genomes and Genes | J WakeleySummaryAffiliation: Rutgers University Country: USA Publications
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Detail Information
Publications
Distinguishing migration from isolation using the variance of pairwise differencesJ Wakeley
Department of Population Genetics, National Institute of Genetics, Mishima, Japan
Theor Popul Biol 49:369-86. 1996..The power and realized significance of the test are investigated using simulations, and an example using mitochondrial DNA illustrates its application...
Estimating ancestral population parametersJ Wakeley
Department of Biological Sciences, Rutgers University, Piscataway, New Jersey 08855 1059, USA
Genetics 145:847-55. 1997..Computer simulations show that current and historical population parameters can be estimated accurately. The methods are applied to DNA data from two species of Drosophila and to some human mitochondrial DNA sequences...
Using the variance of pairwise differences to estimate the recombination rateJ Wakeley
Department of Biological Sciences, Rutgers University, New Jersey, USA
Genet Res 69:45-8. 1997..The variance of the average number of pairwise differences is also derived, and is important in the formulation of the new estimator...
Segregating sites in Wright's island modelJ Wakeley
Department of Biological Sciences, Rutgers, University, New Jersey, USA
Theor Popul Biol 53:166-74. 1998..A new estimator of the population migration rate is proposed and is shown to outperform the widely used pairwise method...
The population genetics of the origin and divergence of the Drosophila simulans complex speciesR M Kliman
Department of Genetics, Rutgers University, Piscataway, New Jersey 08854 8082, USA
Genetics 156:1913-31. 2000..The exception is one gene copy at one locus in D. sechellia, which closely resembled other D. simulans sequences. The overall picture is of two allopatric speciation events that occurred quite near one another in time...
Gene flow and natural selection in the origin of Drosophila pseudoobscura and close relativesR L Wang
Biological Sciences, Rutgers University, Nelson Labs, Piscataway, New Jersey 08855 1059, USA
Genetics 147:1091-106. 1997..This family of models includes some sympatric and parapatric speciation models, as well as models of secondary contact and subsequent reinforcement of sexual isolation...
A coalescent estimator of the population recombination rateJ Hey
Department of Ecology, Evolution and Natural Resources, Nelson Laboratories, Rutgers University, Piscataway, New Jersey 08855 1059, USA
Genetics 145:833-46. 1997..If there exists an independent estimate of the recombination rate (per generation, per base pair), gamma can be used to estimate the effective population size or the neutral mutation rate...
The coalescent in an island model of population subdivision with variation among demesJ Wakeley
Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts 02138, USA
Theor Popul Biol 59:133-44. 2001....
Directional selection and the site-frequency spectrumC D Bustamante
Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts 02138, USA
Genetics 159:1779-88. 2001..We also find that the LRT is not robust to deviations from the assumption of independence among sites...
Recent trends in population genetics: more data! More math! Simple models?J Wakeley
Department of Organismic and Evolutionary Biology, Harvard University, 2102 Biological Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
J Hered 95:397-405. 2004....
Effects of intra-gene fitness interactions on the benefit of sexual recombinationR A Watson
Natural Systems Group, School of Electronics and Computer Science, Southampton University, Southampton, UK
Biochem Soc Trans 34:560-1. 2006....
Expected coalescence times and segregating sites in a model of glacial cyclesF F Jesus
Departamento de Genetica e Evolucao, Instituto de Biologia, UNICAMP, Campinas, SP, Brasil
Genet Mol Res 5:466-74. 2006..This points to the importance of population structure in the history of species subject to climatic fluctuations, and helps explain the long gene genealogies observed in several organisms...
