Research Topics
Genomes and Genes | N TavernarakisSummaryAffiliation: Rutgers University Country: USA Publications
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Detail Information
Publications
Gene overexpression reveals alternative mechanisms that induce GCN4 mRNA translationN Tavernarakis
Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology, Heraklion, Crete, Greece
Gene 179:271-7. 1996....
Caenorhabditis elegans degenerins and vertebrate ENaC ion channels contain an extracellular domain related to venom neurotoxinsN Tavernarakis
Department of Molecular Biology and Biochemistry, Nelson Biological Laboratories, Rutgers University, Piscataway, NJ 08855, USA
J Neurogenet 13:257-64. 2000..Since venom neurotoxins bind to sodium channels at high affinity, we suggest that the related domain embedded in DEG/ENaC channels may interact with other regions of the channel or channel complex to modulate channel function...
Degenerins. At the core of the metazoan mechanotransducer?N Tavernarakis
Department of Molecular Biology and Biochemistry, Rutgers, State University of New Jersey, Piscataway, New Jersey 08855, USA
Ann N Y Acad Sci 940:28-41. 2001..Still-to-be-discovered DEG/ENaC proteins may compose the core of the elusive human mechanotransducer...
Necrotic cell death in C. elegans requires the function of calreticulin and regulators of Ca(2+) release from the endoplasmic reticulumK Xu
Department of Molecular Biology and Biochemistry, A232, Nelson Biological Laboratories, Rutgers, The State University of New Jersey, 604 Allison Road, Piscataway, NJ 08855, USA
Neuron 31:957-71. 2001..elegans and suggest that an essential step in the death mechanism is release of ER-based Ca(2+) stores. ER-driven Ca(2+) release has previously been implicated in mammalian necrosis, suggesting necrotic death mechanisms may be conserved...
Acquisition of a potential marker for insect transformation: isolation of a novel alcohol dehydrogenase gene from Bactrocera oleae by functional complementation in yeastP Benos
Institute of Molecular Biology and Biotechnology, FORTH, Heraklion, Crete, Greece
Mol Gen Genet 263:90-5. 2000....
In vivo imaging of neurodegeneration in Caenorhabditis elegans by third harmonic generation microscopyE J Gualda
Institute of Electronic Structure and Laser, Foundation of Research and Technology Hellas, 71110 Heraklion, Crete, Greece
J Microsc 232:270-5. 2008..Thus, the THG image contrast modality comprises a powerful diagnostic tool, providing valuable information and offering new insights into morphological changes and complex developmental processes in live biological specimens...
Imaging Caenorhabditis elegans embryogenesis by third-harmonic generation microscopyG J Tserevelakis
Institute of Electronic Structure and Laser, Foundation of Research and Technology Hellas, P O Box 1385, 71110, Heraklion, Crete, Greece
Micron 41:444-7. 2010..THG image contrast modality proved as a powerful diagnostic tool, providing valuable information and offering new insights into the complex developmental process of C. elegans embryogenesis...
In vivo imaging of cell morphology and cellular processes in Caenorhabditis elegans, using non-linear phenomenaG Filippidis
Institute of Electronic Structure and Laser, Foundation of Research and Technology Hellas, P O Box 1385, 71110 Heraklion, Crete, Greece
Micron 40:876-80. 2009..Moreover, THG imaging technique has been tested as a potential, novel, non-destructive diagnostic tool for monitoring cellular processes in vivo, such as neuronal degeneration...
Transcriptional interference caused by GCN4 overexpression reveals multiple interactions mediating transcriptional activationN Tavernarakis
Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology, Heraklion, Crete, Greece
Mol Gen Genet 247:571-8. 1995..Our results suggest that the AFR1 gene product is involved in the mediation of transcriptional activation...
Molecules that mediate touch transduction in the nematode Caenorhabditis elegansM Driscoll
Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ 08855, USA
Gravit Space Biol Bull 10:33-42. 1997..In the extracelluar matrix, collagen MEC-5 and MEC-9 and MEC-1 may interact with extracellular channel domains. A molecular model for mechanotransduction is discussed...
Mechanotransduction in Caenorhabditis elegans: the role of DEG/ENaC ion channelsN Tavernarakis
Department of Molecular Biology and Biochemistry, Rutgers, The State University of New Jersey, New Brunswick, USA
Cell Biochem Biophys 35:1-18. 2001....
Autophagy is required for necrotic cell death in Caenorhabditis elegansC Samara
Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology, Heraklion, Crete, Greece
Cell Death Differ 15:105-12. 2008..Our findings demonstrate that autophagy contributes to cellular destruction during necrosis. Thus, interfering with the autophagic process may protect neurons against necrotic damage in humans...
unc-8, a DEG/ENaC family member, encodes a subunit of a candidate mechanically gated channel that modulates C. elegans locomotionN Tavernarakis
Department of Molecular Biology and Biochemistry, Rutgers, The State University of New Jersey, Piscataway 08855, USA
Neuron 18:107-19. 1997..del-1, a second DEG/ENaC family member coexpressed with unc-8 in a subset of motor neurons, might also participate in a channel that contributes to nematode proprioception...
Autophagy and cell death in model organismsN Kourtis
Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, Heraklion 71110, Crete, Greece
Cell Death Differ 16:21-30. 2009..In this review, we survey current research in simple organisms, linking autophagy to cell death and discuss the complex interplay between autophagy, cell survival and cell death...
Germ line transformation of the olive fly Bactrocera oleae using a versatile transgenesis markerM Koukidou
Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology, Heraklion, Crete, Greece
Insect Mol Biol 15:95-103. 2006..The self-activating gene construct combined with transposase mRNA present a system with potential for transgenesis of very diverse species...
In vivo imaging of cellular structures in Caenorhabditis elegans by combined TPEF, SHG and THG microscopyE J Gualda
Institute of Electronic Structure and Laser, Foundation of Research and Technology Hellas, 71110, Heraklion, Crete, Greece
J Microsc 229:141-50. 2008....
