Tracey Shors

Summary

Affiliation: Rutgers University
Country: USA

Publications

  1. ncbi request reprint The modulation of Pavlovian memory
    T J Shors
    Department of Psychology and Center for Neuroscience, Rutgers University, 152 Frelinghuysen Road, Piscataway, NJ 08903, USA
    Behav Brain Res 110:39-52. 2000
  2. pmc Stressful experience and learning across the lifespan
    Tracey J Shors
    Department of Psychology, Center for Collaborative Neuroscience, Rutgers University, Piscataway, New Jersey 08854, USA
    Annu Rev Psychol 57:55-85. 2006
  3. pmc Significant life events and the shape of memories to come: a hypothesis
    Tracey J Shors
    Department of Psychology, Center for Collaborative Neuroscience, Rutgers University, USA
    Neurobiol Learn Mem 85:103-15. 2006
  4. pmc Memory traces of trace memories: neurogenesis, synaptogenesis and awareness
    Tracey J Shors
    Department of Psychology, Center for Collaborative Neuroscience, Rutgers University, 152 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Trends Neurosci 27:250-6. 2004
  5. pmc Learning during stressful times
    Tracey J Shors
    Department of Psychology, Center for Collaborative Neuroscience, Rutgers University, Piscataway, New Jersey 08854, USA
    Learn Mem 11:137-44. 2004
  6. pmc The opposite effects of stress on dendritic spines in male vs. female rats are NMDA receptor-dependent
    T J Shors
    Department of Psychology, Center for Collaborative Neuroscience, 152 Frelinghuysen Road, Rutgers University, Piscataway, NJ 08854 8020, USA
    Eur J Neurosci 19:145-50. 2004
  7. pmc Can new neurons replace memories lost?
    Tracey J Shors
    Department of Psychology, Rutgers University, Piscataway, NJ 08854, USA
    Sci Aging Knowledge Environ 2003:pe35. 2003
  8. pmc Estrogen-mediated effects on depression and memory formation in females
    Tracey J Shors
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, 152 Frelinghuysen Road, Piscataway, NJ 08854 8020, USA
    J Affect Disord 74:85-96. 2003
  9. ncbi request reprint Neurogenesis in the adult is involved in the formation of trace memories
    T J Shors
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, Piscataway, New Jersey 08854, USA
    Nature 410:372-6. 2001
  10. ncbi request reprint Acute stress persistently enhances estrogen levels in the female rat
    T J Shors
    Department of Psychology and Center for Neuroscience Rutgers University, Piscataway, NJ 08854 8020, USA
    Stress 3:163-71. 1999

Collaborators

Detail Information

Publications46

  1. ncbi request reprint The modulation of Pavlovian memory
    T J Shors
    Department of Psychology and Center for Neuroscience, Rutgers University, 152 Frelinghuysen Road, Piscataway, NJ 08903, USA
    Behav Brain Res 110:39-52. 2000
    ..It is our contention that identifying the hormonal and neuronal processes that modulate associative memory formation will provide insight into the processes of memory formation itself...
  2. pmc Stressful experience and learning across the lifespan
    Tracey J Shors
    Department of Psychology, Center for Collaborative Neuroscience, Rutgers University, Piscataway, New Jersey 08854, USA
    Annu Rev Psychol 57:55-85. 2006
    ....
  3. pmc Significant life events and the shape of memories to come: a hypothesis
    Tracey J Shors
    Department of Psychology, Center for Collaborative Neuroscience, Rutgers University, USA
    Neurobiol Learn Mem 85:103-15. 2006
    ..It is proposed that these modulatory processes allow past experiences to change the shape of memories to come. In this way, memorable life events become less about the past and more about the future...
  4. pmc Memory traces of trace memories: neurogenesis, synaptogenesis and awareness
    Tracey J Shors
    Department of Psychology, Center for Collaborative Neuroscience, Rutgers University, 152 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Trends Neurosci 27:250-6. 2004
    ..More recent findings implicate neurogenesis, synaptogenesis and awareness in the formation of trace memories...
  5. pmc Learning during stressful times
    Tracey J Shors
    Department of Psychology, Center for Collaborative Neuroscience, Rutgers University, Piscataway, New Jersey 08854, USA
    Learn Mem 11:137-44. 2004
    ..An appreciation for its plasticity may provide new avenues for investigating its underlying neuronal mechanisms...
  6. pmc The opposite effects of stress on dendritic spines in male vs. female rats are NMDA receptor-dependent
    T J Shors
    Department of Psychology, Center for Collaborative Neuroscience, 152 Frelinghuysen Road, Rutgers University, Piscataway, NJ 08854 8020, USA
    Eur J Neurosci 19:145-50. 2004
    ..These data suggest that both increases and decreases in spine density can be dependent on NMDA receptor activation...
  7. pmc Can new neurons replace memories lost?
    Tracey J Shors
    Department of Psychology, Rutgers University, Piscataway, NJ 08854, USA
    Sci Aging Knowledge Environ 2003:pe35. 2003
    ....
  8. pmc Estrogen-mediated effects on depression and memory formation in females
    Tracey J Shors
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, 152 Frelinghuysen Road, Piscataway, NJ 08854 8020, USA
    J Affect Disord 74:85-96. 2003
    ....
  9. ncbi request reprint Neurogenesis in the adult is involved in the formation of trace memories
    T J Shors
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, Piscataway, New Jersey 08854, USA
    Nature 410:372-6. 2001
    ..These results indicate that newly generated neurons in the adult are not only affected by the formation of a hippocampal-dependent memory, but also participate in it...
  10. ncbi request reprint Acute stress persistently enhances estrogen levels in the female rat
    T J Shors
    Department of Psychology and Center for Neuroscience Rutgers University, Piscataway, NJ 08854 8020, USA
    Stress 3:163-71. 1999
    ....
  11. ncbi request reprint Acute stress rapidly and persistently enhances memory formation in the male rat
    T J Shors
    Department of Psychology and Center for Neuroscience, Rutgers University, Piscataway, New Jersey 08854 8020, USA
    Neurobiol Learn Mem 75:10-29. 2001
    ..These studies extend the circumstances under which stress is known to enhance associative learning and implicate neural mechanisms of memory enhancement that are rapidly induced and persistently expressed...
  12. ncbi request reprint Sex differences and opposite effects of stress on dendritic spine density in the male versus female hippocampus
    T J Shors
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, Piscataway, New Jersey 08854, USA
    J Neurosci 21:6292-7. 2001
    ..In summary, males and females have different levels of dendritic spine density in the hippocampus under unstressed conditions, and their neuronal anatomy can respond in opposite directions to the same stressful event...
  13. pmc Testosterone in utero and at birth dictates how stressful experience will affect learning in adulthood
    Tracey J Shors
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, Piscataway, NJ 08854 8020, USA
    Proc Natl Acad Sci U S A 99:13955-60. 2002
    ..As with many sexual behaviors, these cognitive responses to stress appear to be masculinized by exposure to testosterone and feminized by its absence during very early development...
  14. pmc Neurogenesis may relate to some but not all types of hippocampal-dependent learning
    Tracey J Shors
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, Piscataway, New Jersey 08854 8020, USA
    Hippocampus 12:578-84. 2002
    ..Nor did MAM treatment affect exploration in the elevated plus maze. These results combined with previous ones suggest that neurogenesis may be associated with the formation of some but not all types of hippocampal-dependent memories...
  15. ncbi request reprint Females do not express learned helplessness like males do
    Christina Dalla
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, Piscataway, NJ 08854, USA
    Neuropsychopharmacology 33:1559-69. 2008
    ..Learned helplessness may not constitute a valid model for depressive behavior in women, at least as reflected by the response of female rats to operant conditioning procedures after stressful experience...
  16. ncbi request reprint Is there a link between adult neurogenesis and learning?
    Benedetta Leuner
    Department of Psychology, Princeton University, Princeton, New Jersey 08544, USA
    Hippocampus 16:216-24. 2006
    ..This review discusses both sides of this issue, considering the effects of learning on the production of new neurons in the dentate gyrus and the question of whether newly born cells participate in learning and memory...
  17. pmc Developmental mercury exposure elicits acute hippocampal cell death, reductions in neurogenesis, and severe learning deficits during puberty
    Anthony Falluel-Morel
    Department of Neuroscience and Cell Biology, UMDNJ Robert Wood Johnson Medical School, Piscataway, New Jersey, USA
    J Neurochem 103:1968-81. 2007
    ..In aggregate, these studies indicate that exposure to one dose of MeHg during the perinatal period acutely induces apoptotic cell death, which results in later deficits in hippocampal structure and function...
  18. pmc Female rats learn trace memories better than male rats and consequently retain a greater proportion of new neurons in their hippocampi
    Christina Dalla
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, Piscataway, NJ 08854, USA
    Proc Natl Acad Sci U S A 106:2927-32. 2009
    ..Thus, sex differences in learning alter the anatomical structure of the hippocampus. As a result, male and female brains continue to differentiate in adulthood...
  19. pmc Neurogenesis, learning and associative strength
    Jaylyn Waddell
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, Piscataway, NJ 08854, USA
    Eur J Neurosci 27:3020-8. 2008
    ..Thus, learning can rescue the majority of cells expressed at the beginning of training, and does so most effectively when acquisition requires many trials...
  20. pmc d-cycloserine reverses the detrimental effects of stress on learning in females and enhances retention in males
    Jaylyn Waddell
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, Piscataway, NJ 08854, USA
    Neurobiol Learn Mem 93:31-6. 2010
    ..Thus, as shown previously, training in the presence of an NMDA receptor agonist enhances associative learning and memory retention. In addition, it can reverse learning deficits that have already been induced...
  21. pmc Neurogenesis and the spacing effect: learning over time enhances memory and the survival of new neurons
    Helene M Sisti
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, Piscataway, New Jersey, USA
    Learn Mem 14:368-75. 2007
    ..They also indicate that learning over an extended period of time induces a more persistent memory, which then relates to the number of cells that reside in the hippocampus...
  22. pmc Distinctive stress effects on learning during puberty
    Georgia E Hodes
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, 152 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Horm Behav 48:163-71. 2005
    ..Together, these data indicate that males and female respond similarly to learning opportunities and stressful experience before and during puberty; it is in adulthood that sex differences and the opposite responses to stress arise...
  23. pmc Sex differences in learning processes of classical and operant conditioning
    Christina Dalla
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, Piscataway, New Jersey 08854, USA
    Physiol Behav 97:229-38. 2009
    ..Finally, we discuss how sex differences in learning continue to alter the brain throughout the lifespan. Thus, sex differences in learning are not only mediated by sex differences in the brain, but also contribute to them...
  24. pmc Males and females respond differently to controllability and antidepressant treatment
    Benedetta Leuner
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, 153 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Biol Psychiatry 56:964-70. 2004
    ..Here, we tested whether these opposite effects in males versus females could be prevented by establishing control over the stressor or by antidepressant treatment...
  25. pmc The neuropeptide VGF produces antidepressant-like behavioral effects and enhances proliferation in the hippocampus
    Smita Thakker-Varia
    Department of Neuroscience and Cell Biology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway, New Jersey 08854 5635, USA
    J Neurosci 27:12156-67. 2007
    ..Thus, VGF may act downstream of BDNF and exert its effects as an antidepressant-like agent by enhancing neurogenesis in the hippocampus...
  26. pmc The basolateral nucleus of the amygdala is necessary to induce the opposing effects of stressful experience on learning in males and females
    Jaylyn Waddell
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, Piscataway, New Jersey 08854, USA
    J Neurosci 28:5290-4. 2008
    ..Thus, the BLA is necessary to induce the long-term effect of stressful experience on conditioning regardless of sex and direction of modulation...
  27. pmc Neurogenesis and learning: acquisition and asymptotic performance predict how many new cells survive in the hippocampus
    Christina Dalla
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, Piscataway, NJ 08854, USA
    Neurobiol Learn Mem 88:143-8. 2007
    ..These data support the idea that learning and not simply training increases the survival of the new cells in the hippocampus...
  28. pmc Neurogenesis and helplessness are mediated by controllability in males but not in females
    Tracey J Shors
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, Piscataway, New Jersey 08854, USA
    Biol Psychiatry 62:487-95. 2007
    ..Here, we tested the hypothesis that uncontrollable but not controllable stress would reduce cell proliferation in the hippocampus of male and female rats and would relate to the expression of helplessness behavior...
  29. doi request reprint From stem cells to grandmother cells: how neurogenesis relates to learning and memory
    Tracey J Shors
    Department of Psychology, Rutgers University, Piscataway, NJ 08854, USA
    Cell Stem Cell 3:253-8. 2008
    ..This commentary considers how learning enhances the survival of neural stem/progenitor cell progeny and what these new neurons might do once they are rescued from death...
  30. pmc The hippocampus is necessary for enhancements and impairments of learning following stress
    Debra A Bangasser
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, 152 Frelinghuysen Road, Piscataway, New Jersey 08854, USA
    Nat Neurosci 10:1401-3. 2007
    ..Thus, the hippocampus is necessary for modifying learning in males and females after acute stressful experience...
  31. pmc Stressful experience has opposite effects on dendritic spines in the hippocampus of cycling versus masculinized females
    Christina Dalla
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, 152 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Neurosci Lett 449:52-6. 2009
    ..Such a process may represent a mechanism for altering learning abilities after an acute traumatic experience...
  32. pmc The bed nucleus of the stria terminalis modulates learning after stress in masculinized but not cycling females
    Debbie A Bangasser
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, Piscataway, New Jersey 08854, USA
    J Neurosci 28:6383-7. 2008
    ..Importantly, together these studies indicate that males and females can engage different brain structures to modulate learning after a stressful experience...
  33. pmc Acute stress impairs trace eye blink conditioning in females without altering the unconditioned response
    Debra A Bangasser
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, Piscataway, NJ, USA
    Neurobiol Learn Mem 82:57-60. 2004
    ..Taken together, these experiments indicate that the stress-induced impairment of conditioning in females is not due to a decreased perception of US strength...
  34. pmc Learning enhances the survival of new neurons beyond the time when the hippocampus is required for memory
    Bendetta Leuner
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, Piscataway, New Jersey 08854, USA
    J Neurosci 24:7477-81. 2004
    ....
  35. pmc Temporal discontiguity is neither necessary nor sufficient for learning-induced effects on adult neurogenesis
    Benedetta Leuner
    Department of Psychology, Princeton University, Princeton, New Jersey 08544, USA
    J Neurosci 26:13437-42. 2006
    ..Together, these results demonstrate that associative learning increases the survival of new neurons in the adult hippocampus, regardless of temporal contiguity...
  36. pmc Associative memory formation increases the observation of dendritic spines in the hippocampus
    Benedetta Leuner
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, Piscataway, New Jersey 08854, USA
    J Neurosci 23:659-65. 2003
    ..These results suggest that the formation and expression of associative memories increase the availability of dendritic spines and the potential for synaptic contact...
  37. pmc Brain-derived neurotrophic factor-induced gene expression reveals novel actions of VGF in hippocampal synaptic plasticity
    Janet Alder
    Department of Neuroscience and Cell Biology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway, New Jersey 08854 5635, USA
    J Neurosci 23:10800-8. 2003
    ..These observations indicate that gene profiling in vitro can reveal new mechanisms of synaptic strengthening associated with learning and memory...
  38. pmc Learning during middle age: a resistance to stress?
    Georgia E Hodes
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, 152 Frelinghuysen Road, Piscataway, NJ 08854, United States
    Neurobiol Aging 28:1783-8. 2007
    ..Together, these data indicate that associative learning in the aging animal is resistant to both the negative and positive consequences of stressful experience...
  39. pmc The bed nucleus of the stria terminalis is critically involved in enhancing associative learning after stressful experience
    Debra A Bangasser
    Department of Psychology, Rutgers University, Piscataway, NJ 08854, USA
    Behav Neurosci 119:1459-66. 2005
    ..These data indicate that stressful experience induces persistent changes in the BNST that are necessary for enhancing learning well after the stressful event has ceased...
  40. pmc New spines, new memories
    Benedetta Leuner
    Department of Psychology, Center for Collaborative Neuroscience, Rutgers University, Piscataway, NJ 08854, USA
    Mol Neurobiol 29:117-30. 2004
    ..With this scheme, learning is not dependent on changes in spine density but rather changes in the presence of dendritic spines provide anatomical support for the processing of novel information used in memory formation...
  41. pmc Trace conditioning and the hippocampus: the importance of contiguity
    Debra A Bangasser
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, Piscataway, New Jersey 08854, USA
    J Neurosci 26:8702-6. 2006
    ..Therefore, the dependence of traditional trace paradigms on the hippocampus can be attributed to the absence of temporal contiguity...
  42. pmc Learning during motherhood: A resistance to stress
    Benedetta Leuner
    Department of Psychology and Center for Collaborative Neuroscience, Rutgers University, 152 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Horm Behav 50:38-51. 2006
    ..Together, these data suggest that the presence of offspring and the nurturing and care-giving activities that they elicit protect females from the adverse effect of stress on processes involved in learning and memory...
  43. pmc Growth hormone is produced within the hippocampus where it responds to age, sex, and stress
    Christine P Donahue
    Department of Neurology, Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 103:6031-6. 2006
    ..These results suggest that GH may be involved in functions ascribed to the hippocampus, such as learning and the response to stressful experience...
  44. pmc Glucocorticoids are necessary for enhancing the acquisition of associative memories after acute stressful experience
    Anna V Beylin
    Department of Psychology and Program in Neuroscience, Princeton University, Princeton, NJ 08544, USA
    Horm Behav 43:124-31. 2003
    ....
  45. pmc Estrogen and learning: strategy over parsimony
    Tracey J Shors
    Learn Mem 12:84-5. 2005

Research Grants11

  1. Effects of Stress on Memory Formation and Plasticity
    Tracey Shors; Fiscal Year: 2002
    ..In addition, they are relevant to post traumatic stress disorder (PTSD), a disease marked by the persistent behavioral and neuronal consequences of stressful experience. ..
  2. Stress and Memory Formation Across the Female Lifespan
    Tracey Shors; Fiscal Year: 2009
    ..abstract_text> ..
  3. Stress and Memory Formation Across the Female Lifespan
    Tracey Shors; Fiscal Year: 2007
    ..abstract_text> ..
  4. Stress and Memory Formation Across the Female Lifespan
    Tracey Shors; Fiscal Year: 2006
    ..abstract_text> ..
  5. Stress and Memory Formation Across the Female Lifespan
    Tracey Shors; Fiscal Year: 2005
    ..abstract_text> ..
  6. Stress and Memory Formation Across the Female Lifespan
    Tracey Shors; Fiscal Year: 2004
    ..abstract_text> ..
  7. Stress and Memory Formation Across the Female Lifespan
    Tracey Shors; Fiscal Year: 2003
    ..abstract_text> ..
  8. Effects of Stress on Memory Formation and Plasticity
    Tracey Shors; Fiscal Year: 2001
    ..In addition, they are relevant to post traumatic stress disorder (PTSD), a disease marked by the persistent behavioral and neuronal consequences of stressful experience. ..
  9. Opposing Effects of Stress on Memory Formation and Plast
    Tracey Shors; Fiscal Year: 2000
    ..In addition, they are relevant to post traumatic stress disorder (PTSD), a disease marked by the persistent behavioral and neuronal consequences of stressful experience. ..
  10. AMYGDALA & SEXUALLY OPPOSED EFFECT OF STRESS ON LEARNING
    Tracey Shors; Fiscal Year: 1999
    ..In addition, they are relevant to post traumatic stress disorder (PTSD), a disease marked by the persistent behavioral and neuronal consequences of stressful experience. ..