Bandaru Reddy

Summary

Affiliation: Rutgers University
Country: USA

Publications

  1. ncbi request reprint Chemoprophylaxis of colon cancer
    Bandaru S Reddy
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    Curr Gastroenterol Rep 7:389-95. 2005
  2. ncbi request reprint Prevention of colon cancer by low doses of celecoxib, a cyclooxygenase inhibitor, administered in diet rich in omega-3 polyunsaturated fatty acids
    Bandaru S Reddy
    Susan Lehman Cullman Laboratory for Cancer Research, Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers State University of New Jersey, Piscataway, New Jersey 08854, USA
    Cancer Res 65:8022-7. 2005
  3. ncbi request reprint Prevention of azoxymethane-induced colon cancer by combination of low doses of atorvastatin, aspirin, and celecoxib in F 344 rats
    Bandaru S Reddy
    Susan Lehman Cullman Laboratory for Cancer Research, Department of Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, USA
    Cancer Res 66:4542-6. 2006
  4. ncbi request reprint Strategies for colon cancer prevention: combination of chemopreventive agents
    Bandaru S Reddy
    Susan Lehman Cullman Laboratory for Cancer Research, USA
    Subcell Biochem 42:213-25. 2007
  5. ncbi request reprint Identification of Nrf2-regulated genes induced by chemopreventive isothiocyanate PEITC by oligonucleotide microarray
    Rong Hu
    Graduate Program in Pharmaceutical Science, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    Life Sci 79:1944-55. 2006
  6. ncbi request reprint Pharmacogenomics of cancer chemopreventive isothiocyanate compound sulforaphane in the intestinal polyps of ApcMin/+ mice
    Tin Oo Khor
    Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    Biopharm Drug Dispos 27:407-20. 2006
  7. pmc Atorvastatin and celecoxib in combination inhibits the progression of androgen-dependent LNCaP xenograft prostate tumors to androgen independence
    Xi Zheng
    Department of Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, 08854, USA
    Cancer Prev Res (Phila) 3:114-24. 2010
  8. ncbi request reprint Combined inhibitory effects of curcumin and phenethyl isothiocyanate on the growth of human PC-3 prostate xenografts in immunodeficient mice
    Tin Oo Khor
    Center for Cancer Prevention Research, Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers The State University of New Jersey, 160 Freilinghuysen Road, Piscataway, NJ 08854, USA
    Cancer Res 66:613-21. 2006
  9. pmc Murine prostate cancer inhibition by dietary phytochemicals--curcumin and phenyethylisothiocyanate
    Avantika Barve
    Graduate Program in Pharmaceutical Sciences, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, USA
    Pharm Res 25:2181-9. 2008
  10. doi request reprint Mixed tocotrienols inhibit prostate carcinogenesis in TRAMP mice
    Avantika Barve
    Rutgers, The State University of New Jersey, 160 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Nutr Cancer 62:789-94. 2010

Research Grants

Collaborators

Detail Information

Publications48

  1. ncbi request reprint Chemoprophylaxis of colon cancer
    Bandaru S Reddy
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    Curr Gastroenterol Rep 7:389-95. 2005
    ....
  2. ncbi request reprint Prevention of colon cancer by low doses of celecoxib, a cyclooxygenase inhibitor, administered in diet rich in omega-3 polyunsaturated fatty acids
    Bandaru S Reddy
    Susan Lehman Cullman Laboratory for Cancer Research, Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers State University of New Jersey, Piscataway, New Jersey 08854, USA
    Cancer Res 65:8022-7. 2005
    ..These studies support the use of low doses of celecoxib in omega-3 PUFA-rich diet as a promising approach for clinical trials...
  3. ncbi request reprint Prevention of azoxymethane-induced colon cancer by combination of low doses of atorvastatin, aspirin, and celecoxib in F 344 rats
    Bandaru S Reddy
    Susan Lehman Cullman Laboratory for Cancer Research, Department of Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, USA
    Cancer Res 66:4542-6. 2006
    ..These observations are of clinical significance because this can pave the way for the use of combinations of these agents in small doses against colon cancer...
  4. ncbi request reprint Strategies for colon cancer prevention: combination of chemopreventive agents
    Bandaru S Reddy
    Susan Lehman Cullman Laboratory for Cancer Research, USA
    Subcell Biochem 42:213-25. 2007
    ....
  5. ncbi request reprint Identification of Nrf2-regulated genes induced by chemopreventive isothiocyanate PEITC by oligonucleotide microarray
    Rong Hu
    Graduate Program in Pharmaceutical Science, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    Life Sci 79:1944-55. 2006
    ....
  6. ncbi request reprint Pharmacogenomics of cancer chemopreventive isothiocyanate compound sulforaphane in the intestinal polyps of ApcMin/+ mice
    Tin Oo Khor
    Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    Biopharm Drug Dispos 27:407-20. 2006
    ....
  7. pmc Atorvastatin and celecoxib in combination inhibits the progression of androgen-dependent LNCaP xenograft prostate tumors to androgen independence
    Xi Zheng
    Department of Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, 08854, USA
    Cancer Prev Res (Phila) 3:114-24. 2010
    ..Our results indicate that administration of a combination of atorvastatin and celecoxib may be an effective strategy for the prevention of prostate cancer progression from androgen dependence to androgen independence...
  8. ncbi request reprint Combined inhibitory effects of curcumin and phenethyl isothiocyanate on the growth of human PC-3 prostate xenografts in immunodeficient mice
    Tin Oo Khor
    Center for Cancer Prevention Research, Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers The State University of New Jersey, 160 Freilinghuysen Road, Piscataway, NJ 08854, USA
    Cancer Res 66:613-21. 2006
    ..Furthermore, we found that combination of PEITC and curcumin could be effective in the cancer-therapeutic treatment of prostate cancers...
  9. pmc Murine prostate cancer inhibition by dietary phytochemicals--curcumin and phenyethylisothiocyanate
    Avantika Barve
    Graduate Program in Pharmaceutical Sciences, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, USA
    Pharm Res 25:2181-9. 2008
    ..Hence, this study was undertaken to examine the potential chemopreventive properties of the two agents against transgenic adenocarcinoma of the mouse prostate...
  10. doi request reprint Mixed tocotrienols inhibit prostate carcinogenesis in TRAMP mice
    Avantika Barve
    Rutgers, The State University of New Jersey, 160 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Nutr Cancer 62:789-94. 2010
    ..Taken together, our results show that by modulating cell cycle regulatory proteins and increasing expression of proapoptotic proteins, mixed tocotrienols suppress prostate tumorigenesis in the TRAMP mice...
  11. ncbi request reprint Cancer chemoprevention of intestinal polyposis in ApcMin/+ mice by sulforaphane, a natural product derived from cruciferous vegetable
    Rong Hu
    Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    Carcinogenesis 27:2038-46. 2006
    ....
  12. doi request reprint Gamma-tocopherol-enriched mixed tocopherol diet inhibits prostate carcinogenesis in TRAMP mice
    Avantika Barve
    Graduate Program in Pharmaceutical Sciences, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ, USA
    Int J Cancer 124:1693-9. 2009
    ..Gamma-T-enriched mixed tocopherols significantly up-regulated the expression of Nrf2 and its related detoxifying and antioxidant enzymes thereby suppressing PIN and tumor development...
  13. ncbi request reprint Gene expression profiles induced by cancer chemopreventive isothiocyanate sulforaphane in the liver of C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice
    Rong Hu
    Graduate Program in Pharmaceutical Science, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, 160 Frelinghuysen, Piscataway, NJ 08854, USA
    Cancer Lett 243:170-92. 2006
    ....
  14. doi request reprint Effects of combination of calcium and aspirin on azoxymethane-induced aberrant crypt foci formation in the colons of mice and rats
    Yingying Liu
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854 8020, USA
    Nutr Cancer 60:660-5. 2008
    ..These results indicate that the combination of calcium and aspirin did not produce a synergistic effect on the ACF formation in AOM-treated mice and rats...
  15. doi request reprint Combination of atorvastatin and celecoxib synergistically induces cell cycle arrest and apoptosis in colon cancer cells
    Hang Xiao
    Susan Lehman Cullman Laboratory for Cancer Research, Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    Int J Cancer 122:2115-24. 2008
    ..The present work suggests the possible therapeutic application of this combination and provides leads for mechanistic and biomarker investigations in clinical trials...
  16. ncbi request reprint Mixed tocopherols inhibit azoxymethane-induced aberrant crypt foci in rats
    Harold L Newmark
    Susan Lehman Cullman Laboratory for Cancer Research, Department of Chemical Biology, Rutgers The State University of New Jersey, 164 Frelinghuysen Road, Piscataway, NJ 08854 8020, USA
    Nutr Cancer 56:82-5. 2006
    ..Mixed tocopherols also reduced tetradecanoyl phorbol acetate-induced ear inflammation in mice when topically applied...
  17. ncbi request reprint Pterostilbene, an active constituent of blueberries, suppresses aberrant crypt foci formation in the azoxymethane-induced colon carcinogenesis model in rats
    Nanjoo Suh
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, USA
    Clin Cancer Res 13:350-5. 2007
    ..Pterostilbene, a naturally occurring stilbene from blueberries, was tested for its preventive activity against colon carcinogenesis...
  18. ncbi request reprint Atorvastatin and celecoxib inhibit prostate PC-3 tumors in immunodeficient mice
    Xi Zheng
    Susan Lehman Cullman Laboratory for Cancer Research, Department of Chemical Biology, The State University of New Jersey, Piscataway, New Jersey 08854, USA
    Clin Cancer Res 13:5480-7. 2007
    ..To investigate the effects and mechanisms of atorvastatin and celecoxib administered individually or in combination on human prostate cancer PC-3 cells cultured in vitro or grown as xenograft tumors in immunodeficient mice...
  19. ncbi request reprint Green tea polyphenols inhibit colorectal aberrant crypt foci (ACF) formation and prevent oncogenic changes in dysplastic ACF in azoxymethane-treated F344 rats
    Hang Xiao
    Susan Lehman Cullman Laboratory for Cancer Research, Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854 8020, USA
    Carcinogenesis 29:113-9. 2008
    ..Taken together, our results strongly suggest the colon cancer-preventive activity of PPE and identified possible molecular markers for future colon cancer prevention studies...
  20. ncbi request reprint Chemoprevention of familial adenomatous polyposis by natural dietary compounds sulforaphane and dibenzoylmethane alone and in combination in ApcMin/+ mouse
    Guoxiang Shen
    Center for Cancer Prevention Research, Department of Pharmaceutics, and Susan Lehman Cullman Laboratory for Cancer Research, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, USA
    Cancer Res 67:9937-44. 2007
    ..In conclusion, our results showed that both SFN and DBM alone as well as their combination are potent natural dietary compounds for chemoprevention of gastrointestinal cancers...
  21. ncbi request reprint Mixed tocopherols inhibit N-methyl-N-nitrosourea-induced mammary tumor growth in rats
    Nanjoo Suh
    Department of Chemical Biology, The State University of New Jersey, Piscataway, NJ 08854, USA
    Nutr Cancer 59:76-81. 2007
    ..The treatment increased the serum levels of gamma- and delta-tocopherols without affecting the body weight. The results of this study suggest that mixed tocopherols may be safe and effective agents for the prevention of breast cancer...
  22. ncbi request reprint Inhibition of EGFR signaling in human prostate cancer PC-3 cells by combination treatment with beta-phenylethyl isothiocyanate and curcumin
    Jung Hwan Kim
    Center for Cancer Prevention Research, Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    Carcinogenesis 27:475-82. 2006
    ....
  23. pmc Anti-inflammatory action of pterostilbene is mediated through the p38 mitogen-activated protein kinase pathway in colon cancer cells
    Shiby Paul
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, 164 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Cancer Prev Res (Phila) 2:650-7. 2009
    ..Our data suggest that the p38 mitogen-activated protein kinase cascade is a key signal transduction pathway for eliciting the anti-inflammatory action of pterostilbene in cultured HT-29 colon cancer cells...
  24. ncbi request reprint Chemoprevention of familial adenomatous polyposis in Apc(Min/+) mice by phenethyl isothiocyanate (PEITC)
    Tin Oo Khor
    Center for Cancer Prevention Research, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    Mol Carcinog 47:321-5. 2008
    ..In conclusion, our results demonstrate that PEITC is a potent natural dietary compound for chemoprevention of gastrointestinal cancers. Its mechanism of actions may include induction of apoptosis and cell cycle arrest...
  25. ncbi request reprint Wheat bran oil and its fractions inhibit human colon cancer cell growth and intestinal tumorigenesis in Apc(min/+) mice
    Shengmin Sang
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers University, 164 Frelinghuysen Road, Piscataway, New Jersey 08854 8020, USA
    J Agric Food Chem 54:9792-7. 2006
    ..The current results demonstrate, for the first time, the intestinal cancer preventive activity of WB oil. The active ingredients, however, remain to be identified...
  26. pmc Increased susceptibility of Nrf2 knockout mice to colitis-associated colorectal cancer
    Tin Oo Khor
    Center for Cancer Prevention Research and Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, 160 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Cancer Prev Res (Phila) 1:187-91. 2008
    ..Our findings show that Nrf2 plays a critical role in protecting against inflammation-associated colorectal cancer...
  27. ncbi request reprint Exisulind in combination with celecoxib modulates epidermal growth factor receptor, cyclooxygenase-2, and cyclin D1 against prostate carcinogenesis: in vivo evidence
    Bhagavathi A Narayanan
    Department of Environmental Medicine, New York University School of Medicine, Tuxedo, New York 10987, USA
    Clin Cancer Res 13:5965-73. 2007
    ..In this study, we determined the combined effect of celecoxib, a COX-2 inhibitor, along with exisulind (sulindac sulfone/Aptosyn) at low doses in prostate cancer...
  28. ncbi request reprint Novel approaches for colon cancer prevention by cyclooxygenase-2 inhibitors
    Bandaru S Reddy
    Nutritional Carcinogenesis and Chemoprevention Program, American Health Foundation, Valhalla, NY 10595, USA
    J Environ Pathol Toxicol Oncol 21:155-64. 2002
    ..Of further importance would be to identify molecular targets that are critical in the growth and survival of the malignant colorectal cell and are modulated by NSAIDs and COX-2 inhibitors...
  29. ncbi request reprint Suppression of N-methyl-N-nitrosourea/testosterone-induced rat prostate cancer growth by celecoxib: effects on cyclooxygenase-2, cell cycle regulation, and apoptosis mechanism(s)
    Bhagavathi A Narayanan
    Division of Nutritional Carcinogenesis, American Health Foundation, Valhalla, New York 10595, USA
    Clin Cancer Res 9:3503-13. 2003
    ..Moreover, we attempted to demonstrate the expression of genes involved in the downstream events related to cyclooxygenase-2 (COX-2) regulation and apoptosis...
  30. ncbi request reprint Lamin B, caspase-3 activity, and apoptosis induction by a combination of HMG-CoA reductase inhibitor and COX-2 inhibitors: a novel approach in developing effective chemopreventive regimens
    Malisetty V Swamy
    Chemoprevention Program, Division of Nutritional Carcinogenesis, American Health Foundation, Valhalla, NY 10595, USA
    Int J Oncol 20:753-9. 2002
    ....
  31. ncbi request reprint Chemopreventive properties of a selective inducible nitric oxide synthase inhibitor in colon carcinogenesis, administered alone or in combination with celecoxib, a selective cyclooxygenase-2 inhibitor
    Chinthalapally V Rao
    Chemoprevention Program, American Health Foundation, Valhalla, New York 10595, USA
    Cancer Res 62:165-70. 2002
    ..These findings support the hypothesis that selective iNOS inhibitors may have chemopreventive properties and that coadministration with a selective COX-2 inhibitor may have additional chemopreventive potential...
  32. ncbi request reprint Down-regulation of PLK3 gene expression by types and amount of dietary fat in rat colon tumors
    Wei Dai
    American Health Foundation, Valhalla, NY 10595, USA
    Int J Oncol 20:121-6. 2002
    ..These observations suggest for the first time that a decreased activity of PLK3 may play a key role in colon tumor development as well as in HFCO-induced colon tumorigenesis...
  33. ncbi request reprint Chemopreventive effect of farnesol and lanosterol on colon carcinogenesis
    Chinthalapally V Rao
    Division of Nutritional Carcinogenesis, American Health Foundation, One Dana Road, Valhalla, NY 10595, USA
    Cancer Detect Prev 26:419-25. 2002
    ..01) levels. That farnesol and lanosterol significantly suppress colonic ACF formation and crypt multiplicity strengthens the hypothesis that these agents possess chemopreventive activity against colon carcinogenesis...
  34. ncbi request reprint Enhancement of development of azoxymethane-induced colonic premalignant lesions in C57BL/KsJ-db/db mice
    Yoshinobu Hirose
    Department of Tumor Pathology, Gifu University School of Medicine, 40 Tsukasa Machi, Gifu 500 8705, Japan
    Carcinogenesis 25:821-5. 2004
    ..The results have important implications for further exploration of the possible underlying events that affect the positive association between colon cancer and chronic diseases (obesity and diabetes)...
  35. ncbi request reprint A combination of docosahexaenoic acid and celecoxib prevents prostate cancer cell growth in vitro and is associated with modulation of nuclear factor-kappaB, and steroid hormone receptors
    Narayanan K Narayanan
    Department of Environmental Medicine, New York University School of Medicine, Tuxedo, NY 10987, USA
    Int J Oncol 26:785-92. 2005
    ..This raises the intriguing prospect that the use of low doses of a COX-2 inhibitor in combination with an n-3 PUFA could be a highly promising strategy for prostate cancer chemoprevention while minimizing undesired side effects...
  36. ncbi request reprint Sphingosine kinase 1 is up-regulated in colon carcinogenesis
    Toshihiko Kawamori
    Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    FASEB J 20:386-8. 2006
    ..These results suggest that the SK1/S1P pathway may play an important role in colon carcinogenesis, in part, by regulating COX-2 expression and PGE2 production...
  37. ncbi request reprint Regression of mouse prostatic intraepithelial neoplasia by nonsteroidal anti-inflammatory drugs in the transgenic adenocarcinoma mouse prostate model
    Bhagavathi A Narayanan
    Cancer Genomics Laboratory, Chemoprevention and Nutritional Carcinogenesis Program, and Statistics and Data Management, Institute for Cancer Prevention, Valhalla, New York 10987, USA
    Clin Cancer Res 10:7727-37. 2004
    ..The toxicity associated with these compounds is raising concerns, and more needs to be known about their mode of action and molecular targets...
  38. ncbi request reprint Low doses of beta-carotene and lutein inhibit AOM-induced rat colonic ACF formation but high doses augment ACF incidence
    Jayadev Raju
    Chemoprevention Program, Institute for Cancer Prevention, American Health Foundation Cancer Center, Valhalla, NY, USA
    Int J Cancer 113:798-802. 2005
    ..Taken together these data indicate that the chemopreventive activity of beta-carotene and lutein against colon carcinogenesis depends on the dose level...
  39. ncbi request reprint Nitric oxide-releasing aspirin and indomethacin are potent inhibitors against colon cancer in azoxymethane-treated rats: effects on molecular targets
    Chinthalapally V Rao
    Department of Medicine, Hem Onc Section, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Mol Cancer Ther 5:1530-8. 2006
    ..These results pave the way for the rational design of human clinical trials...
  40. ncbi request reprint Studies with the azoxymethane-rat preclinical model for assessing colon tumor development and chemoprevention
    Bandaru S Reddy
    Division of Nutritional Carcinogenesis, Institute for Cancer Prevention, Valhalla, New York, NY 10595, USA
    Environ Mol Mutagen 44:26-35. 2004
    ..Of further importance is to identify whether the molecular targets that are critical in the growth and survival of the malignant colorectal cell are modulated by n-3 PUFAs, NSAIDs, or COX-2 and iNOS inhibitors...
  41. ncbi request reprint Chemoprevention of familial adenomatous polyposis by low doses of atorvastatin and celecoxib given individually and in combination to APCMin mice
    Malisetty V Swamy
    Department of Medicine, Hem Onc Section, University of Oklahoma Cancer Institute, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
    Cancer Res 66:7370-7. 2006
    ..These observations show that atorvastatin inhibits intestinal tumorigenesis and that, importantly, when given together with low doses of celecoxib, it significantly increases the chemopreventive efficacy in an APC(min) mice...
  42. ncbi request reprint Methionine restriction inhibits colon carcinogenesis
    Despina Komninou
    Institute of Cancer, Valhalla, NY 10595, USA
    Nutr Cancer 54:202-8. 2006
    ..05). These results show that MR inhibits colonic tumor development in the rat, an effect that occurs primarily during post-initiation phases of carcinogenesis and may be due, in part, to an inhibition of colonic cell proliferation...
  43. ncbi request reprint Modulation of cyclooxygenase-2 activities by the combined action of celecoxib and decosahexaenoic acid: novel strategies for colon cancer prevention and treatment
    Malisetty V Swamy
    Chemoprevention and Nutritional Carcinogenesis Program, Institute for Cancer Prevention, American Health Foundation Cancer Center, Valhalla, NY, USA
    Mol Cancer Ther 3:215-21. 2004
    ..We are currently testing this concept in preclinical models...
  44. ncbi request reprint Adenocarcina of the mouse prostate growth inhibition by celecoxib: downregulation of transcription factors involved in COX-2 inhibition
    Bhagavathi A Narayanan
    Department of Environmental Medicine, New York University School of Medicine, Tuxedo, New York 10987, USA
    Prostate 66:257-65. 2006
    ..In this study, we examined a dose-dependent effect of a cyclooxygenase-2 (COX-2) inhibitor, celecoxib against transgenic adenocarcinoma of the mouse prostate...
  45. ncbi request reprint NSAIDs and chemoprevention
    Chinthalapally V Rao
    Chemoprevention Program, Institute for Cancer Prevention, American Health Foundation Cancer Center, 1 Dana Road, Valhalla, NY 10595, USA
    Curr Cancer Drug Targets 4:29-42. 2004
    ..There is growing optimism for the view that full exploration of the role of NSAIDs in the prevention and treatment of epithelial cancers will serve towards reducing of mortality and morbidity from various cancers...
  46. ncbi request reprint Effects of a combination of docosahexaenoic acid and 1,4-phenylene bis(methylene) selenocyanate on cyclooxygenase 2, inducible nitric oxide synthase and beta-catenin pathways in colon cancer cells
    Bhagavathi A Narayanan
    Chemoprevention and Nutritional Carcinogenesis Program, Institute for Cancer Prevention Valhalla, NY 10595, USA
    Carcinogenesis 25:2443-9. 2004
    ....
  47. ncbi request reprint Omega-3 fatty acids in colorectal cancer prevention
    Bandaru S Reddy
    Division of Nutritional Carcinogenesis, American Health Foundation Cancer Center, Institute for Cancer Prevention, Valhalla, NY 10595, USA
    Int J Cancer 112:1-7. 2004
  48. ncbi request reprint Modulation of inducible nitric oxide synthase and related proinflammatory genes by the omega-3 fatty acid docosahexaenoic acid in human colon cancer cells
    Bhagavathi A Narayanan
    Microarray Unit, Molecular Pathology and Bioinformatics and Division of Nutritional Carcinogenesis, American Health Foundation, Valhalla, New York 10595, USA
    Cancer Res 63:972-9. 2003
    ..In addition, our results indicate the presence of specific gene expression profiles in human colon cancer that can be used as molecular targets for chemopreventive agents...

Research Grants19

  1. TYPES AND AMOUNT OF DIETARY FAT AND COLON CANCER
    Bandaru Reddy; Fiscal Year: 2002
    ..It is hoped that the results generated from the proposed mechanistic study will strengthen the rationale for primary and secondary prevention of colon cancer through dietary modulation. ..
  2. CALORIES/ENERGY EXPENDITURE/FISH OIL--COLON CANCER
    Bandaru Reddy; Fiscal Year: 1990
    ..Colon tumor incidence will be compared among the groups fed ad libitum and calorie-restricted diets and those subjected to exercise...
  3. TYPES OF DIETARY FAT AND COLON CANCER
    Bandaru Reddy; Fiscal Year: 1993
    ..The selected biochemical parameters taken together would suggest the possible mechanism of in vivo tumor promotion or inhibition by types of dietary fat...
  4. COX-2 Inhibitor and N-3PUFA in Colon Cancer Prevention
    Nanjoo Suh; Fiscal Year: 2007
    ..Clear delineation of the synergistic effects in preclinical models will allow the rational design of human clinical trials. ..