Research Topics
| H M KipenSummaryAffiliation: Rutgers University Country: USA Publications
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Publications
A 37-year-old mechanic with multiple chemical sensitivitiesH M Kipen
Environmental and Occupational Health Sciences Institute and UMDNJ Robert Wood Johnson Medical School, Piscataway, NJ 08854, USA
Environ Health Perspect 108:377-81. 2000..Careful exclusion of organic causes is critical, and this should be followed by a judicious approach to coping with symptoms...
Measurement of inflammation and oxidative stress following drastic changes in air pollution during the Beijing Olympics: a panel study approachHoward Kipen
University of Medicine and Dentistry of New Jersey School of Public Health and Robert Wood Johnson Medical School, Piscataway, New Jersey, USA
Ann N Y Acad Sci 1203:160-7. 2010..This study should lead to a clearer and more precise definition of the role of oxidative and nitrosative stress, as well as other mechanisms, in determining acute morbidity and mortality from air pollution exposure...
Acute decreases in proteasome pathway activity after inhalation of fresh diesel exhaust or secondary organic aerosolHoward M Kipen
Clinical Research and Occupational Medicine Division, Environmental and Occupational Health Sciences Institute, Piscataway, New Jersey 08854, USA
Environ Health Perspect 119:658-63. 2011..The proteasome is an intracellular protein degradation system linked to both of these processes and may help mediate air pollution effects...
Environmental factors in medically unexplained symptoms and related syndromes: the evidence and the challengeHoward M Kipen
Environmental and Occupational Health Sciences Institute Occupational Health Division, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
Environ Health Perspect 110:597-9. 2002..It is time to develop a comprehensive research agenda to sort out nomenclature, epidemiology, and environmental causation for these conditions, moving toward comprehensive and effective public health and clinical approaches...
The role of environmental factors in medically unexplained symptoms and related syndromes: conference summary and recommendationsHoward M Kipen
Environmental and Occupational Health Sciences Institute, University of Medicine and Dentistry Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
Environ Health Perspect 110:591-5. 2002..Recommendations were made for a series of epidemiologic, psychosocial, and experimental research approaches, with acknowledgment that nosology issues are clearly fundamental to advancing understanding of these conditions...
Controlled exposures to volatile organic compounds in sensitive groupsN Fiedler
UMDNJ Robert Wood Johnson Medical School, Environmental and Occupational Health Sciences Institute, Piscataway, New Jersey 08854, USA
Ann N Y Acad Sci 933:24-37. 2001..However, these studies suggest that symptoms are not necessarily accompanied by changes in physiologic arousal. Subject characteristics play a critical role in outcomes...
The vomeronasal organ and chemical sensitivity: a hypothesisGlenn J Greene
Environmental and Occupational Health Sciences Institute, Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
Environ Health Perspect 110:655-61. 2002..Beyond relevance to CS, the demonstration of an active, adult VNO could have significant impact on environmental toxicology...
Pulmonary effects of inhaled limonene ozone reaction products in elderly ratsVasanthi R Sunil
Department of Pharmacology and Toxicology, Rutgers University, Piscataway, NJ 08854, USA
Toxicol Appl Pharmacol 222:211-20. 2007..LOP are pulmonary irritants inducing distinct inflammatory responses in younger and older animals. This may contribute to the differential sensitivity of these populations to pulmonary irritants...
Negative affect and chemical intolerance as risk factors for building-related symptoms: a controlled exposure studyNancy Fiedler
Department of Environmental and Occupational Medicine, UMDNJ Robert Wood Johnson Medical School, EOHSI 170 Frelinghuysen Road, Piscataway, NJ 08854, USA
Psychosom Med 70:254-62. 2008..To assess whether differences in negative affect (NA) and chemical intolerance (CI) affect responses to chemical mixtures and stress in a controlled experimental model...
Lack of association between estimated World Trade Center plume intensity and respiratory symptoms among New York City residents outside of Lower ManhattanRobert J Laumbach
Environmental and Occupational Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, 170 Frelinghuysen Road, Piscataway, NJ 08854, USA
Am J Epidemiol 170:640-9. 2009..9% vs. 16.6%; odds ratio = 1.0, 95% confidence interval: 0.3, 2.8). These results suggest that the plume was not strongly associated with respiratory symptoms outside of Lower Manhattan, within the limitations of this retrospective study...
Pulmonary effects of inhaled diesel exhaust in aged miceVasanthi R Sunil
Department of Pharmacology and Toxicology, Rutgers University, Ernest Mario School of Pharmacy, 160 Frelinghuysen Road, Piscataway, NJ 08854, USA
Toxicol Appl Pharmacol 241:283-93. 2009..Taken together, these results suggest that altered generation of inflammatory mediators and MnSOD may contribute to increased susceptibility of older mice to inhaled DE...
Acute changes in heart rate variability in subjects with diabetes following a highway traffic exposureRobert J Laumbach
Division of Clinical Research and Occupational Medicine, Department of Environmental and Occupational Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway, NJ 08854, USA
J Occup Environ Med 52:324-31. 2010..To pilot a protocol to evaluate acute cardiovascular effects in in-vehicle exposure to traffic air pollutants in people with diabetes...
Acute effects of motor vehicle traffic-related air pollution exposures on measures of oxidative stress in human airwaysRobert J Laumbach
University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, New Jersey, USA
Ann N Y Acad Sci 1203:107-12. 2010..Promising biomarkers include nitric oxide in exhaled breath, and nitrite/nitrate, malondialdehyde, and F2-isoprostanes in exhaled breath condensate...
Nasal effects of a mixture of volatile organic compounds and their ozone oxidation productsRobert J Laumbach
Environmental and Occupational Health Sciences Institute, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
J Occup Environ Med 47:1182-9. 2005....
Military deployment to the Gulf War as a risk factor for psychiatric illness among US troopsNancy Fiedler
Department of Environmental and Occupational Medicine and Dentistry of New Jersey, UMDNJ Robert Wood Johnson Medical School, 170 Frelinghuysen Road, Piscataway, NJ 08854, USA
Br J Psychiatry 188:453-9. 2006..Several studies document an excess of psychiatric symptoms among veterans of the the 1991 Gulf War. However, little is known about the prevalence of psychiatric disorders in those who were deployed to that conflict...
Symptom patterns among Gulf War registry veteransWilliam K Hallman
New Jersey Center for Environmental Hazards Research, East Orange, USA
Am J Public Health 93:624-30. 2003..We identify symptom patterns among veterans who believe they suffer from Gulf War-related illnesses and characterize groups of individuals with similar patterns...
Bioaerosols and sick building syndrome: particles, inflammation, and allergyRobert J Laumbach
Environmental and Occupational Health Sciences Institute, UMDNJ Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
Curr Opin Allergy Clin Immunol 5:135-9. 2005..This review of recent literature will attempt to put into context the roles of allergy and nonallergic mechanisms in sick building syndrome...
A pilot study of telephone-based smoking cessation intervention in asbestos workersOmowunmi Y O Osinubi
Division of Environmental and Occupational Health, University of Medicine and Dentistry of New Jersey School of Public Health, Environmental and Occupational Sciences Institute, 170 Frelinghuysen Road, Piscataway, NJ 08854, USA
J Occup Environ Med 45:569-74. 2003..Incorporating telephone-based smoking cessation treatment into medical screening activities for asbestos workers is feasible and the intervention is effective in increasing quit rates at 6 months...
Right heart pressure increases after acute increases in ambient particulate concentrationDavid Q Rich
School of Public Health, University of Medicine and Dentistry of New Jersey, Piscataway, New Jersey 08854, USA
Environ Health Perspect 116:1167-71. 2008..5 microm (PM(2.5))] as an explanation for previous associations between congestive heart failure (HF) hospital admissions and PM...
Reported exposures, stressors, and life events among Gulf War Registry veteransKendal C Boyd
Department of Human Ecology, Rutgers, The State University of New Jersey, New Brunswick, 08901, USA
J Occup Environ Med 45:1247-56. 2003..Models seeking to explain Gulf War symptoms need to incorporate a range of exposure and psychosocial factors to fully account for important influences...
Why do people report better health by phone than by mail?Noel T Brewer
Department of Health Behavior and Health Education, School of Public Health, University of North Carolina, Chapel Hill, North Carolina 27599, USA
Med Care 42:875-83. 2004..Past research shows that fewer health symptoms are reported by phone than by mail...
Unexplained symptoms after terrorism and war: an expert consensus statementDaniel J Clauw
Department of Medicine, University of Michigan School of Medicine, USA
J Occup Environ Med 45:1040-8. 2003..An international, multidisciplinary, and multiinstitutional consensus project was completed to summarize current knowledge on unexplained symptoms after terrorism and war...
Smaller is not always better: nanotechnology yields nanotoxicologyHoward M Kipen
Am J Physiol Lung Cell Mol Physiol 289:L696-7. 2005
Persistence of symptoms in veterans of the First Gulf War: 5-year follow-upGozde Ozakinci
Bute Medical School, University of St. Andrews, St. Andrews, Fife, Scotland, United Kingdom
Environ Health Perspect 114:1553-7. 2006..CONCLUSIONS: The symptom outbreak following the 1991 Gulf War has not abated over time in registry veterans, suggesting substantial need for better understanding and care for these veterans...
