Sastry S Isukapalli

Summary

Affiliation: Rutgers University
Country: USA

Publications

  1. pmc Bayesian Analysis of a Lipid-Based Physiologically Based Toxicokinetic Model for a Mixture of PCBs in Rats
    Alan F Sasso
    Environmental and Occupational Health Sciences Institute, UMDNJ RW Johnson Medical School, Rutgers University, 170 Frelinghuysen Road, Piscataway, NJ 08854, USA
    J Toxicol 2012:895391. 2012
  2. pmc Exposure indices for the National Children's Study: application to inhalation exposures in Queens County, NY
    Sastry S Isukapalli
    Environmental and Occupational Health Science Institute, EOHSI, 170 Frelinghuysen Road, Piscataway, New Jersey 08854, USA
    J Expo Sci Environ Epidemiol 23:22-31. 2013
  3. pmc A unified multiscale field/network/agent based modeling framework for human and ecological health risk analysis
    Panos G Georgopoulos
    Environmental and Occupational Health Sciences Institute, a joint institute of UMDNJ RW Johnson Medical School and Rutgers University, Piscataway, NJ 08854, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:6420-3. 2009
  4. pmc Using national and local extant data to characterize environmental exposures in the national children's study: Queens County, New York
    Paul J Lioy
    Environmental and Occupational Health Sciences Institute, University of Medicine and Dentistry, New Jersey Robert Wood Johnson Medical School and Rutgers University, Piscataway, New Jersey, USA
    Environ Health Perspect 117:1494-504. 2009
  5. pmc A generalized physiologically-based toxicokinetic modeling system for chemical mixtures containing metals
    Alan F Sasso
    Environmental and Occupational Health Sciences Institute, a joint institute of UMDNJ Robert Wood Johnson Medical School and Rutgers University, Piscataway, New Jersey, USA
    Theor Biol Med Model 7:17. 2010
  6. pmc Mathematical model of uptake and metabolism of arsenic(III) in human hepatocytes - Incorporation of cellular antioxidant response and threshold-dependent behavior
    Spyros K Stamatelos
    Environmental and Occupational Health Sciences Institute EOHSI, a joint institute of UMDNJ Robert Wood Johnson Medical School and Rutgers University, 170 Frelinghuysen Rd, Piscataway, NJ 08854, USA
    BMC Syst Biol 5:16. 2011
  7. pmc Reconstructing population exposures to environmental chemicals from biomarkers: challenges and opportunities
    Panos G Georgopoulos
    Environmental and Occupational Health Sciences Institute EOHSI, a joint institute of UMDNJ RW Johnson Medical School and Rutgers University, Piscataway, NJ 08854, USA
    J Expo Sci Environ Epidemiol 19:149-71. 2009
  8. pmc Differential gene expression profiling of mouse skin after sulfur mustard exposure: Extended time response and inhibitor effect
    Donald R Gerecke
    Environmental and Occupational Health Sciences Institute EOHSI, a joint institute of UMDNJ RW Johnson Medical School and Rutgers University, 170 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Toxicol Appl Pharmacol 234:156-65. 2009
  9. pmc Studying permethrin exposure in flight attendants using a physiologically based pharmacokinetic model
    Binnian Wei
    Environmental and Occupational Health Sciences Institute, A Joint Institute of Rutgers University and University of Medicine and Dentistry of New Jersey, Piscataway, New Jersey 08854, USA
    J Expo Sci Environ Epidemiol 23:416-27. 2013

Collaborators

Detail Information

Publications9

  1. pmc Bayesian Analysis of a Lipid-Based Physiologically Based Toxicokinetic Model for a Mixture of PCBs in Rats
    Alan F Sasso
    Environmental and Occupational Health Sciences Institute, UMDNJ RW Johnson Medical School, Rutgers University, 170 Frelinghuysen Road, Piscataway, NJ 08854, USA
    J Toxicol 2012:895391. 2012
    ..The linked PBTK/induction model remained on a lipid basis and was capable of modeling PCB concentrations in multiple tissues for all dose levels and dose profiles...
  2. pmc Exposure indices for the National Children's Study: application to inhalation exposures in Queens County, NY
    Sastry S Isukapalli
    Environmental and Occupational Health Science Institute, EOHSI, 170 Frelinghuysen Road, Piscataway, New Jersey 08854, USA
    J Expo Sci Environ Epidemiol 23:22-31. 2013
    ..The results also serve as an example application of the EI for use in other exposure and outcome studies...
  3. pmc A unified multiscale field/network/agent based modeling framework for human and ecological health risk analysis
    Panos G Georgopoulos
    Environmental and Occupational Health Sciences Institute, a joint institute of UMDNJ RW Johnson Medical School and Rutgers University, Piscataway, NJ 08854, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:6420-3. 2009
    ..These examples include problems describing human health risk assessment, ecological risk assessment, and environmentally caused disease...
  4. pmc Using national and local extant data to characterize environmental exposures in the national children's study: Queens County, New York
    Paul J Lioy
    Environmental and Occupational Health Sciences Institute, University of Medicine and Dentistry, New Jersey Robert Wood Johnson Medical School and Rutgers University, Piscataway, New Jersey, USA
    Environ Health Perspect 117:1494-504. 2009
    ..To fill major data gaps, extant data will be required for each study location. The Queens Vanguard Center has examined the extent of those needs and the types of data that are generally and possibly locally available...
  5. pmc A generalized physiologically-based toxicokinetic modeling system for chemical mixtures containing metals
    Alan F Sasso
    Environmental and Occupational Health Sciences Institute, a joint institute of UMDNJ Robert Wood Johnson Medical School and Rutgers University, Piscataway, New Jersey, USA
    Theor Biol Med Model 7:17. 2010
    ..There is a need, therefore, for a consistent modeling framework that would allow the systematic study of cumulative risks from complex mixtures of contaminants...
  6. pmc Mathematical model of uptake and metabolism of arsenic(III) in human hepatocytes - Incorporation of cellular antioxidant response and threshold-dependent behavior
    Spyros K Stamatelos
    Environmental and Occupational Health Sciences Institute EOHSI, a joint institute of UMDNJ Robert Wood Johnson Medical School and Rutgers University, 170 Frelinghuysen Rd, Piscataway, NJ 08854, USA
    BMC Syst Biol 5:16. 2011
    ..Notable features of this model are the incorporation of arsenic-glutathione complex formation and a "switch-like" formulation to describe the antioxidant response of hepatocytes to arsenic exposure...
  7. pmc Reconstructing population exposures to environmental chemicals from biomarkers: challenges and opportunities
    Panos G Georgopoulos
    Environmental and Occupational Health Sciences Institute EOHSI, a joint institute of UMDNJ RW Johnson Medical School and Rutgers University, Piscataway, NJ 08854, USA
    J Expo Sci Environ Epidemiol 19:149-71. 2009
    ....
  8. pmc Differential gene expression profiling of mouse skin after sulfur mustard exposure: Extended time response and inhibitor effect
    Donald R Gerecke
    Environmental and Occupational Health Sciences Institute EOHSI, a joint institute of UMDNJ RW Johnson Medical School and Rutgers University, 170 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Toxicol Appl Pharmacol 234:156-65. 2009
    ..These results can help in understanding the molecular mechanism of SM-induced blistering, as well as to test the efficacy of different inhibitors...
  9. pmc Studying permethrin exposure in flight attendants using a physiologically based pharmacokinetic model
    Binnian Wei
    Environmental and Occupational Health Sciences Institute, A Joint Institute of Rutgers University and University of Medicine and Dentistry of New Jersey, Piscataway, New Jersey 08854, USA
    J Expo Sci Environ Epidemiol 23:416-27. 2013
    ..3%, 5.0% and 89.7% under pre-flight spray scenario, respectively. The PBPK model provides the capability to simulate the toxicokinetic profiles of permethrin, and can be used in the studies on human exposure to permethrin...