MARION GORDON

Summary

Affiliation: Rutgers University
Country: USA

Publications

  1. pmc Activation of adherent vascular neutrophils in the lung during acute endotoxemia
    Vasanthi R Sunil
    Department of Pharmacology and Toxicology, Rutgers University, 160 Frelinghuysen Road, Piscataway, New Jersey 08854 8020, USA
    Respir Res 3:21. 2002
  2. pmc Doxycycline hydrogels as a potential therapy for ocular vesicant injury
    Marion K Gordon
    Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ 08854, USA
    J Ocul Pharmacol Ther 26:407-19. 2010
  3. pmc Collagens
    Marion K Gordon
    Department of Pharmacology and Toxicology, Rutgers University, Piscataway, NJ, USA
    Cell Tissue Res 339:247-57. 2010
  4. pmc Differential gene expression profiling of mouse skin after sulfur mustard exposure: Extended time response and inhibitor effect
    Donald R Gerecke
    Environmental and Occupational Health Sciences Institute EOHSI, a joint institute of UMDNJ RW Johnson Medical School and Rutgers University, 170 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Toxicol Appl Pharmacol 234:156-65. 2009
  5. pmc UVB light regulates expression of antioxidants and inflammatory mediators in human corneal epithelial cells
    Adrienne T Black
    Pharmacology and Toxicology, Rutgers University, 160 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Biochem Pharmacol 81:873-80. 2011
  6. ncbi request reprint Preferential expression of matrix metalloproteinase-9 in mouse skin after sulfur mustard exposure
    Michael P Shakarjian
    Department of Medicine, UMDNJ Robert Wood Johnson Medical School, Piscataway, NJ 08854 5635, USA
    J Appl Toxicol 26:239-46. 2006
  7. ncbi request reprint Expression of FACIT collagens XII and XIV during bleomycin-induced pulmonary fibrosis in mice
    Eleni G Tzortzaki
    Department of Genetics, Rutgers University, Piscataway, New Jersey 08854, USA
    Anat Rec A Discov Mol Cell Evol Biol 275:1073-80. 2003
  8. ncbi request reprint Exaggerated hepatotoxicity of acetaminophen in mice lacking tumor necrosis factor receptor-1. Potential role of inflammatory mediators
    Carol R Gardner
    Environmental and Occupational Health Sciences Institute, Rutgers University and University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, NJ 08854 8020, USA
    Toxicol Appl Pharmacol 192:119-30. 2003
  9. pmc Regulation of TREM expression in hepatic macrophages and endothelial cells during acute endotoxemia
    Li C Chen
    Rutgers University, Piscataway, New Jersey 08854, USA
    Exp Mol Pathol 84:145-55. 2008
  10. ncbi request reprint Extracellular matrix changes in the umbilical arteries of growth-restricted fetuses
    Wendy L Kinzler
    Department of Obstetrics, Gynecology and Reproductive Sciences, Division of Maternal Fetal Medicine, UMDNJ RWJ Medical School, New Brunswick, NJ, USA
    Am J Obstet Gynecol 192:1053-9. 2005

Research Grants

  1. Matrix and Morphogenesis Conference
    MARION GORDON; Fiscal Year: 2002
  2. Expressions of Specialized Collagens in the Cornea
    MARION GORDON; Fiscal Year: 2007
  3. Expression of Specialized Collagens in the Cornea
    MARION GORDON; Fiscal Year: 2005
  4. REGULATION OF FIBRIL ASSOCIATED COLLAGENS IN CORNEA
    MARION GORDON; Fiscal Year: 2000
  5. Expressions of Specialized Collagens in the Cornea
    Marion K Gordon; Fiscal Year: 2010

Collaborators

Detail Information

Publications11

  1. pmc Activation of adherent vascular neutrophils in the lung during acute endotoxemia
    Vasanthi R Sunil
    Department of Pharmacology and Toxicology, Rutgers University, 160 Frelinghuysen Road, Piscataway, New Jersey 08854 8020, USA
    Respir Res 3:21. 2002
    ..In the present study, we analyzed the effects of acute endotoxemia on the response of a unique subpopulation of neutrophils tightly adhered to the lung vasculature...
  2. pmc Doxycycline hydrogels as a potential therapy for ocular vesicant injury
    Marion K Gordon
    Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ 08854, USA
    J Ocul Pharmacol Ther 26:407-19. 2010
    ....
  3. pmc Collagens
    Marion K Gordon
    Department of Pharmacology and Toxicology, Rutgers University, Piscataway, NJ, USA
    Cell Tissue Res 339:247-57. 2010
    ..Proper tissue function depends on correctly assembled molecular aggregates being incorporated into the matrix. This review highlights some of the structural characteristics of collagen types I-XXVIII...
  4. pmc Differential gene expression profiling of mouse skin after sulfur mustard exposure: Extended time response and inhibitor effect
    Donald R Gerecke
    Environmental and Occupational Health Sciences Institute EOHSI, a joint institute of UMDNJ RW Johnson Medical School and Rutgers University, 170 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Toxicol Appl Pharmacol 234:156-65. 2009
    ..These results can help in understanding the molecular mechanism of SM-induced blistering, as well as to test the efficacy of different inhibitors...
  5. pmc UVB light regulates expression of antioxidants and inflammatory mediators in human corneal epithelial cells
    Adrienne T Black
    Pharmacology and Toxicology, Rutgers University, 160 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Biochem Pharmacol 81:873-80. 2011
    ..Alterations in expression of these mediators are likely to be important in regulating inflammation and protecting the cornea from UVB-induced oxidative stress...
  6. ncbi request reprint Preferential expression of matrix metalloproteinase-9 in mouse skin after sulfur mustard exposure
    Michael P Shakarjian
    Department of Medicine, UMDNJ Robert Wood Johnson Medical School, Piscataway, NJ 08854 5635, USA
    J Appl Toxicol 26:239-46. 2006
    ..These observations suggest the differential expression of MMP-2 and -9 during the cutaneous response to SM injury and suggest a role for MMP-9 in SM-induced injury...
  7. ncbi request reprint Expression of FACIT collagens XII and XIV during bleomycin-induced pulmonary fibrosis in mice
    Eleni G Tzortzaki
    Department of Genetics, Rutgers University, Piscataway, New Jersey 08854, USA
    Anat Rec A Discov Mol Cell Evol Biol 275:1073-80. 2003
    ..These data support the hypothesis that fibrosis is a multistep process that involves both collagen accumulation and changes in the molecules that modulate the biomechanical properties of fibrils...
  8. ncbi request reprint Exaggerated hepatotoxicity of acetaminophen in mice lacking tumor necrosis factor receptor-1. Potential role of inflammatory mediators
    Carol R Gardner
    Environmental and Occupational Health Sciences Institute, Rutgers University and University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, NJ 08854 8020, USA
    Toxicol Appl Pharmacol 192:119-30. 2003
    ..In contrast, increases in IL-10 were more rapid and more pronounced. These data demonstrate that signaling through TNFR1 is important in inflammatory mediator production and toxicity induced by acetaminophen...
  9. pmc Regulation of TREM expression in hepatic macrophages and endothelial cells during acute endotoxemia
    Li C Chen
    Rutgers University, Piscataway, New Jersey 08854, USA
    Exp Mol Pathol 84:145-55. 2008
    ..These results suggest that TREM proteins are important in the inflammatory response of hepatic macrophages and endothelial cells to acute endotoxemia...
  10. ncbi request reprint Extracellular matrix changes in the umbilical arteries of growth-restricted fetuses
    Wendy L Kinzler
    Department of Obstetrics, Gynecology and Reproductive Sciences, Division of Maternal Fetal Medicine, UMDNJ RWJ Medical School, New Brunswick, NJ, USA
    Am J Obstet Gynecol 192:1053-9. 2005
    ..This study was undertaken to determine whether the expression of extracellular matrix components (ECM) is altered in the umbilical arteries from preterm fetal growth-restricted (FGR) pregnancies...
  11. ncbi request reprint Active remodeling in idiopathic interstitial pneumonias: evaluation of collagen types XII and XIV
    Eleni G Tzortzaki
    Department of Thoracic Medicine, University General Hospital Medical School, University of Crete, Heraklion 71110, Crete, Greece
    J Histochem Cytochem 54:693-700. 2006
    ..This may suggest a possible distinct role for both collagens in the modulation of the extracellular matrix during the onset of fibrotic process...

Research Grants15

  1. Matrix and Morphogenesis Conference
    MARION GORDON; Fiscal Year: 2002
    ..This meeting provides a unique opportunity for senior and junior scientists to gather and discuss the latest and most advanced results in the field of extracellular matrix and morphogenesis. ..
  2. Expressions of Specialized Collagens in the Cornea
    MARION GORDON; Fiscal Year: 2007
    ..The alterations in fibril architecture resulting from the dominant negative phenotype will be evaluated by transmission electron microscopy. ..
  3. Expression of Specialized Collagens in the Cornea
    MARION GORDON; Fiscal Year: 2005
    ..This will be accomplished by immunofluorescence with specific antibodies and in situ hybridization with cDNA probes. We will also perform cell fractionations to prove collagen XXIII is a transmembrane molecule. ..
  4. REGULATION OF FIBRIL ASSOCIATED COLLAGENS IN CORNEA
    MARION GORDON; Fiscal Year: 2000
    ..We will use a PCR based strategy to obtain a cDNA for the corneal type XII isoform, to elucidate its structure. ..
  5. Expressions of Specialized Collagens in the Cornea
    Marion K Gordon; Fiscal Year: 2010
    ..The alterations in fibril architecture resulting from the dominant negative phenotype will be evaluated by transmission electron microscopy. ..